Lista de obras - David A. Lee - Dominio Público Uruguay

A specific quantitative assay for collagen synthesis by cells seeded in collagen-based biomaterials using sirius red F3B precipitation

artículo científico publicado en 1998

A system for monitoring the response of uniaxial strain on cell seeded collagen gels

artículo científico publicado en 2000

Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles

artículo científico publicado en 2005

An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties.

artículo científico publicado en 2004

Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment.

artículo científico publicado en 2011

Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes

artículo científico publicado en 2005

Autologous chondrocyte implantation. Culture in a TGF-beta-containing medium enhances the re-expression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture.

artículo científico publicado en 2005

Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen

artículo científico publicado en 2016

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

artículo científico publicado en 2015

Both superficial and deep zone articular chondrocyte subpopulations exhibit the Crabtree effect but have different basal oxygen consumption rates.

artículo científico publicado en 2010

Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus.

artículo científico publicado en 2002

Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment.

artículo científico publicado en 2012

Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs

artículo científico publicado en 2009

Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs

artículo científico publicado en 2004

Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion

artículo científico publicado en 2015

Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields.

artículo científico publicado en 2006

Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels.

artículo científico publicado en 2000

Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose

scientific article published on 01 May 2001

Compressive Deformation and Damage of Muscle Cell Subpopulations in a Model System

article

Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose

artículo científico publicado en 1997

Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose

artículo científico publicado en 2000

Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells

artículo científico publicado en 2012

Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels

artículo científico publicado en 2004

Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture.

artículo científico publicado en 2014

Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles.

artículo científico publicado en 2005

Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification

artículo científico publicado en 2017

Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro

artículo científico publicado en 2008

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

artículo científico publicado en 2016

Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs

artículo científico publicado en 2003

Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.

artículo científico publicado en 2008

Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs

artículo científico publicado en 2001

Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study

artículo científico publicado en 2011

Dynamic mechanical compression influences nitric oxide production by articular chondrocytes seeded in agarose

artículo científico publicado en 1998

Dynamic regulation of nuclear architecture and mechanics-a rheostatic role for the nucleus in tailoring cellular mechanosensitivity.

artículo científico publicado en 2017

Effects of ascorbate on myogenesis in micromass culture

artículo científico publicado en 1990

Electrospray deposited fibronectin retains the ability to promote cell adhesion.

artículo científico publicado en 2011

Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques

artículo científico publicado en 2003

Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain.

artículo científico publicado en 2010

GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment

scientific article published on 11 December 2018

Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading.

artículo científico publicado en 2011

Glucose concentration and medium volume influence cell viability and glycosaminoglycan synthesis in chondrocyte-seeded alginate constructs.

artículo científico publicado en 2006

Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage

artículo científico publicado en 2004

Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels

artículo científico publicado en 2003

Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes

artículo científico publicado en 2006

Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes

artículo científico publicado en 2004

Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes.

artículo científico publicado en 2010

Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression.

artículo científico publicado en 1998

Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose

artículo científico publicado en 2005

Mechanical conditioning influences the metabolic response of cell-seeded constructs.

artículo científico publicado en 2003

Mechanical regulation of nuclear structure and function.

artículo científico publicado en 2012

Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells.

artículo científico publicado en 2016

Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes.

artículo científico publicado en 2008

Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach.

artículo científico publicado en 2005

Oxygen tension modulates the effects of TNFα in compressed chondrocytes

artículo científico publicado en 2016

Proteoglycan depletion alone is not sufficient to stimulate proteoglycan synthesis in cultured bovine cartilage explants

artículo científico publicado en 1994

Quantification of chromatin condensation level by image processing

artículo científico publicado en 2013

Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue

artículo científico publicado en 1996

Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration

artículo científico publicado en 2006

Response of chondrocyte subpopulations cultured within unloaded and loaded agarose

artículo científico publicado en 1998

Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells

artículo científico publicado en 2018

Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression

artículo científico publicado en 2008

Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations.

artículo científico publicado en 2012

Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics.

artículo científico publicado en 2014

Stem cell mechanobiology.

artículo científico publicado en 2011

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor

artículo científico publicado en 2018

Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival

scientific article published on 11 December 2018

Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression

artículo científico publicado en 2003

The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin

artículo científico publicado en 2011

The control of cell division in articular chondrocytes

artículo científico publicado en 1993

The development and characterization of an in vitro system to study strain-induced cell deformation in isolated chondrocytes

artículo científico publicado en 1995

The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties.

artículo científico publicado en 2009

The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose

artículo científico publicado en 1998

The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles.

artículo científico publicado en 2005

The influence of swelling and matrix degradation on the microstructural integrity of tendon.

artículo científico publicado en 2006

The mechanics of flexor tendon adhesions

artículo científico publicado en 2011

The metabolism of human mesenchymal stem cells during proliferation and differentiation.

artículo científico publicado en 2011

Time dependence of cyclic tensile strain on collagen production in tendon fascicles

artículo científico publicado en 2007

Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility.

artículo científico publicado en 2016

Lista de obras de David A. Lee

A specific quantitative assay for collagen synthesis by cells seeded in collagen-based biomaterials using sirius red F3B precipitation

A system for monitoring the response of uniaxial strain on cell seeded collagen gels

Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles

An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties.

Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment.

Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes

Autologous chondrocyte implantation. Culture in a TGF-beta-containing medium enhances the re-expression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture.

Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen

Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells

Both superficial and deep zone articular chondrocyte subpopulations exhibit the Crabtree effect but have different basal oxygen consumption rates.

Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus.

Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment.

Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs

Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs

Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion

Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields.

Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels.

Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose

Compressive Deformation and Damage of Muscle Cell Subpopulations in a Model System

Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose

Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose

Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells

Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels

Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture.

Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles.

Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification

Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs

Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.

Dynamic compression inhibits the synthesis of nitric oxide and PGE(2) by IL-1beta-stimulated chondrocytes cultured in agarose constructs

Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study

Dynamic mechanical compression influences nitric oxide production by articular chondrocytes seeded in agarose

Dynamic regulation of nuclear architecture and mechanics-a rheostatic role for the nucleus in tailoring cellular mechanosensitivity.

Effects of ascorbate on myogenesis in micromass culture

Electrospray deposited fibronectin retains the ability to promote cell adhesion.

Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques

Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain.

GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment

Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading.

Glucose concentration and medium volume influence cell viability and glycosaminoglycan synthesis in chondrocyte-seeded alginate constructs.

Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage

Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels

Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes

Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes

Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes.

Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression.

Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose

Mechanical conditioning influences the metabolic response of cell-seeded constructs.

Mechanical regulation of nuclear structure and function.

Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells.

Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes.

Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach.

Oxygen tension modulates the effects of TNFα in compressed chondrocytes

Proteoglycan depletion alone is not sufficient to stimulate proteoglycan synthesis in cultured bovine cartilage explants

Quantification of chromatin condensation level by image processing

Quantification of sulfated glycosaminoglycans in chondrocyte/alginate cultures, by use of 1,9-dimethylmethylene blue

Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration

Response of chondrocyte subpopulations cultured within unloaded and loaded agarose

Retinoic Acid Receptor-β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin-Driven Activation and Durotaxis in Hepatic Stellate Cells

Signal transduction pathways involving p38 MAPK, JNK, NFkappaB and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1beta and dynamic compression

Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations.

Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics.

Stem cell mechanobiology.

Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor

Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival

Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression

The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin

The control of cell division in articular chondrocytes

The development and characterization of an in vitro system to study strain-induced cell deformation in isolated chondrocytes

The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties.

The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose

The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles.

The influence of swelling and matrix degradation on the microstructural integrity of tendon.

The mechanics of flexor tendon adhesions

The metabolism of human mesenchymal stem cells during proliferation and differentiation.

Time dependence of cyclic tensile strain on collagen production in tendon fascicles

Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility.