Lista de obras - Judith Haendeler - Dominio Público Uruguay

A New Kid on the Block

artículo científico publicado en 2008

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).

artículo científico publicado en 2014

Aging—mechanisms, models, and translation ⬇️

artículo científico publicado el 1 de octubre de 2013

Angiotensin II Induces Transactivation of Two Different Populations of the Platelet-derived Growth Factor β Receptor

scientific article published on 01 May 2000

Angiotensin II mediated signal transduction. Important role of tyrosine kinases.

artículo científico publicado en 2000

Angiotensin II-induced upregulation of MAP kinase phosphatase-3 mRNA levels mediates endothelial cell apoptosis

artículo científico publicado en 2002

Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins

artículo científico publicado en 2004

Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.

artículo científico publicado en 2004

CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.

artículo científico publicado en 2018

Caffeine enhances endothelial repair by an AMPK-dependent mechanism

artículo científico publicado en 2008

Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation

artículo científico publicado en 2012

Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis

artículo científico publicado en 2005

Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes

scientific article published on 05 May 2005

Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging

artículo científico

Changes of MMP-1 and collagen type Ialpha1 by UVA, UVB and IRA are differentially regulated by Trx-1.

artículo científico publicado en 2008

Co-expression of p53 and MDM2 in human atherosclerosis: implications for the regulation of cellularity of atherosclerotic lesions

artículo científico publicado en 1998

Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol

artículo científico publicado en 2000

Critical regulators of endothelial cell functions: for a change being alternative.

artículo científico

Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin

artículo científico publicado en 2002

Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

artículo científico publicado en 1999

Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherin

artículo científico publicado en 2005

Do We Age on Sirt1 Expression?

artículo científico publicado en 2007

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells.

artículo científico publicado en 2009

Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent

artículo científico publicado en 2010

Effects of Granulocyte Colony Stimulating Factor on Functional Activities of Endothelial Progenitor Cells in Patients With Chronic Ischemic Heart Disease

artículo científico publicado en 2006

Effects of redox-related congeners of NO on apoptosis and caspase-3 activity

artículo científico publicado en 1997

Endothelial Cells in Health and Disease

article

Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?

scientific article published on 23 February 2012

Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells

artículo científico publicado en 2007

Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism

artículo científico publicado en 2002

GIT1 Mediates Src-dependent Activation of Phospholipase Cγ by Angiotensin II and Epidermal Growth Factor ⬇️

artículo científico publicado el 30 de septiembre de 2003

GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions

artículo científico publicado en 2004

Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt

scientific journal article

Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration

artículo científico publicado en 2008

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death

artículo científico publicado en 2000

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

artículo científico publicado en 2003

High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

scientific article published on 10 June 2019

Highlight: Oxidative Stress and Senescence

artículo científico publicado en 2008

Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

artículo científico publicado en 2003

Hypoxic induction of the hypoxia-inducible factor is mediated via the adaptor protein Shc in endothelial cells

artículo científico publicado en 2002

Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease

artículo científico publicado en 2005

Increased Protein Tyrosine Phosphatase 1B (PTP1B) Activity and Cardiac Insulin Resistance Precede Mitochondrial and Contractile Dysfunction in Pressure-Overloaded Hearts

scientific article published on 21 June 2018

Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells

scientific article published on 23 November 2018

Inhibition of suicidal erythrocyte death by nitric oxide.

artículo científico publicado en 2007

Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression

artículo científico publicado en 2010

Inseparably tied: functional and antioxidative capacity of endothelial progenitor cells

artículo científico publicado en 2006

Interacting with thioredoxin-1--disease or no disease?

artículo científico

Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules.

artículo científico publicado en 2017

Intra- and Interorgan Communication in the Cardiovascular System: A Special View on Redox Regulation

artículo científico publicado en 2017

Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression

artículo científico publicado en 2004

Measurement of endothelium-dependent vasodilation in mice--brief report.

artículo científico publicado en 2014

Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage

artículo científico publicado en 2009

Molecular mechanisms involved in endothelial cell aging: role of telomerase reverse transcriptase.

artículo científico publicado en 2007

Mouse cardiac mitochondria do not separate in subsarcolemmal and interfibrillar subpopulations.

artículo científico publicado en 2017

Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin Vivo

artículo científico publicado en 1999

Nitric oxide and apoptosis

artículo científico publicado en 1999

Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis

artículo científico publicado en 2000

Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles

artículo científico publicado en 2018

Non-canonical Wnt signaling enhances differentiation of human circulating progenitor cells to cardiomyogenic cells

artículo científico publicado en 2005

Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart

artículo científico publicado en 2016

Nuclear Redox-Signaling Is Essential for Apoptosis Inhibition in Endothelial Cells—Important Role for Nuclear Thioredoxin-1

artículo científico publicado en 2007

Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.

artículo científico publicado en 2008

Nuclear redox signaling

artículo científico publicado en 2010

Oxidative Stress–Induced Degradation of Thioredoxin-1 and Apoptosis Is Inhibited by Thioredoxin-1–Actin Interaction in Endothelial Cells

artículo científico publicado en 2011

Oxidativer Stress im Endothel und bei Diabetes Typ 2

artículo científico publicado en 2012

Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.

artículo científico publicado en 2009

Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis ⬇️

artículo científico publicado el 17 de febrero de 2011

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

artículo científico publicado en 2000

Redox balance in the aged endothelium.

artículo científico

Redox modification of cell signaling in the cardiovascular system

artículo científico publicado en 2012

Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

artículo científico publicado en 2002

Regulation of endothelial cell apoptosis in atherothrombosis

artículo científico publicado en 2002

Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation

artículo científico publicado en 2003

Role of Telomerase in the Cardiovascular System

artículo científico publicado en 2016

SIRT1 controls endothelial angiogenic functions during vascular growth

artículo científico publicado en 2007

Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction

artículo científico publicado en 2003

Shear stress inhibits apoptosis of human endothelial cells

artículo científico publicado en 1996

Silver ion-induced suicidal erythrocyte death.

artículo científico publicado en 2009

Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor

artículo científico publicado en 2006

Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.

artículo científico publicado en 2004

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

artículo científico publicado en 1997

TNFalpha and oxLDL reduce protein S-nitrosylation in endothelial cells

artículo científico publicado en 2001

Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction.

artículo científico publicado en 2008

The Anti-Apoptotic Properties of APEX1 in the Endothelium Require the First 20 Amino Acids and Converge on Thioredoxin-1.

artículo científico publicado en 2016

The aryl hydrocarbon receptor promotes aging phenotypes across species.

artículo científico publicado en 2016

The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4.

artículo científico publicado en 2014

The role of junctional adhesion molecule-C (JAM-C) in oxidized LDL-mediated leukocyte recruitment

artículo científico publicado en 2005

The role of near infrared radiation in photoaging of the skin.

artículo científico publicado en 2008

The transcription factor Grainyhead like 3 (GRHL3) affects endothelial cell apoptosis and migration in a NO-dependent manner.

artículo científico publicado en 2011

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

artículo científico publicado en 2002

Thioredoxin: a key regulator of cardiovascular homeostasis

artículo científico publicado en 2003

Two isoforms of Sister-Of-Mammalian Grainyhead have opposing functions in endothelial cells and in vivo

artículo científico publicado en 2013

Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes

artículo científico publicado en 2012

Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax

artículo científico publicado en 1996

Well-known signaling proteins exert new functions in the nucleus and mitochondria.

scientific article published on August 2010

Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation

artículo científico publicado en 2009

c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy

artículo científico publicado en 2010

p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization

artículo científico publicado en 2004

p38 mitogen-activated protein kinase downregulates endothelial progenitor cells

artículo científico publicado en 2005

Lista de obras de Judith Haendeler

A New Kid on the Block

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).

Aging—mechanisms, models, and translation ⬇️

Angiotensin II Induces Transactivation of Two Different Populations of the Platelet-derived Growth Factor β Receptor

Angiotensin II mediated signal transduction. Important role of tyrosine kinases.

Angiotensin II-induced upregulation of MAP kinase phosphatase-3 mRNA levels mediates endothelial cell apoptosis

Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins

Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.

CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.

Caffeine enhances endothelial repair by an AMPK-dependent mechanism

Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation

Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis

Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes

Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging

Changes of MMP-1 and collagen type Ialpha1 by UVA, UVB and IRA are differentially regulated by Trx-1.

Co-expression of p53 and MDM2 in human atherosclerosis: implications for the regulation of cellularity of atherosclerotic lesions

Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol

Critical regulators of endothelial cell functions: for a change being alternative.

Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin

Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherin

Do We Age on Sirt1 Expression?

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells.

Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent

Effects of Granulocyte Colony Stimulating Factor on Functional Activities of Endothelial Progenitor Cells in Patients With Chronic Ischemic Heart Disease

Effects of redox-related congeners of NO on apoptosis and caspase-3 activity

Endothelial Cells in Health and Disease

Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?

Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells

Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism

GIT1 Mediates Src-dependent Activation of Phospholipase Cγ by Angiotensin II and Epidermal Growth Factor ⬇️

GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions

Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt

Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration

Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes

High Concentration of Low-Density Lipoprotein Results in Disturbances in Mitochondrial Transcription and Functionality in Endothelial Cells

Highlight: Oxidative Stress and Senescence

Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

Hypoxic induction of the hypoxia-inducible factor is mediated via the adaptor protein Shc in endothelial cells

Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease

Increased Protein Tyrosine Phosphatase 1B (PTP1B) Activity and Cardiac Insulin Resistance Precede Mitochondrial and Contractile Dysfunction in Pressure-Overloaded Hearts

Induction of a senescent like phenotype and loss of gap junctional intercellular communication by carbon nanoparticle exposure of lung epithelial cells

Inhibition of suicidal erythrocyte death by nitric oxide.

Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression

Inseparably tied: functional and antioxidative capacity of endothelial progenitor cells

Interacting with thioredoxin-1--disease or no disease?

Interventions to slow cardiovascular aging: Dietary restriction, drugs and novel molecules.

Intra- and Interorgan Communication in the Cardiovascular System: A Special View on Redox Regulation

Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression

Measurement of endothelium-dependent vasodilation in mice--brief report.

Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage

Molecular mechanisms involved in endothelial cell aging: role of telomerase reverse transcriptase.

Mouse cardiac mitochondria do not separate in subsarcolemmal and interfibrillar subpopulations.

Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin Vivo

Nitric oxide and apoptosis

Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis

Non-Canonical Activation of the Epidermal Growth Factor Receptor by Carbon Nanoparticles

Non-canonical Wnt signaling enhances differentiation of human circulating progenitor cells to cardiomyogenic cells

Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart

Nuclear Redox-Signaling Is Essential for Apoptosis Inhibition in Endothelial Cells—Important Role for Nuclear Thioredoxin-1

Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.

Nuclear redox signaling

Oxidative Stress–Induced Degradation of Thioredoxin-1 and Apoptosis Is Inhibited by Thioredoxin-1–Actin Interaction in Endothelial Cells

Oxidativer Stress im Endothel und bei Diabetes Typ 2

Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.

Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis ⬇️

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

Redox balance in the aged endothelium.

Redox modification of cell signaling in the cardiovascular system

Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

Regulation of endothelial cell apoptosis in atherothrombosis

Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation

Role of Telomerase in the Cardiovascular System

SIRT1 controls endothelial angiogenic functions during vascular growth

Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction

Shear stress inhibits apoptosis of human endothelial cells

Silver ion-induced suicidal erythrocyte death.

Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor