Lista de obras - Patrick Doherty - Dominio Público Uruguay

A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists

artículo científico publicado en 2005

A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

artículo científico publicado en 2008

A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade

artículo científico publicado en 2004

A novel live cell assay to measure diacylglycerol lipase α activity

artículo científico publicado en 2016

A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord

artículo científico publicado en 2009

Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons

artículo científico publicado en 2010

Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

artículo científico publicado en 2012

An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

artículo científico publicado en 2002

Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta

artículo científico publicado en 2016

BDNF regulates neuronal sensitivity to endocannabinoids

artículo científico publicado en 2009

Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo

artículo científico publicado en 2004

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

artículo científico publicado en 2003

DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.

artículo científico publicado en 2011

Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists

artículo científico publicado en 2001

Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate

artículo científico publicado en 2002

Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription

artículo científico publicado en 2010

Drebrin regulates neuroblast migration in the postnatal mammalian brain

artículo científico publicado en 2015

Endocannabinoid Turnover

artículo científico publicado en 2017

Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain.

artículo científico publicado en 2011

Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain

artículo científico publicado en 2013

Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists

scientific journal article

Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

artículo científico publicado en 2001

In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices

artículo científico publicado en 2013

Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs

artículo científico publicado en 2004

Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice

scientific journal article

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis

artículo científico publicado en 2006

N-cadherin influences migration of oligodendrocytes on astrocyte monolayers

scientific article published on 01 March 2000

Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function.

artículo científico publicado en 2017

Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless

artículo científico publicado en 2004

Nucleofection of rodent neuroblasts to study neuroblast migration in vitro.

artículo científico publicado en 2013

Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters.

artículo científico publicado en 2009

Overcoming the inhibitors of myelin with a novel neurotrophin strategy

artículo científico publicado en 2004

Polysialyltransferase ST8Sia II (STX) polysialylates all of the major isoforms of NCAM and facilitates neurite outgrowth.

artículo científico publicado en 2001

RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development

artículo científico publicado en 2013

Receptors for myelin inhibitors: Structures and therapeutic opportunities

artículo científico publicado en 2009

Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream

artículo científico publicado en 2014

Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools; implications for endocannabinoid signaling

artículo científico publicado en 2016

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons

artículo científico publicado en 2008

Robo1 and Robo2 are homophilic binding molecules that promote axonal growth

artículo científico publicado en 2002

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides

artículo científico publicado en 2013

The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

artículo científico publicado en 2010

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response

artículo científico publicado en 2003

The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.

artículo científico publicado en 2000

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

artículo científico publicado en 2012

The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation

artículo científico publicado en 2008

The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule

artículo científico publicado en 2006

The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility.

artículo científico publicado en 2000

The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function

artículo científico publicado en 2012

The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond

artículo científico publicado en 2014

Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11

artículo científico publicado en 2013

Lista de obras de Patrick Doherty

A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists

A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade

A novel live cell assay to measure diacylglycerol lipase α activity

A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord

Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons

Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta

BDNF regulates neuronal sensitivity to endocannabinoids

Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.

Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists

Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate

Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription

Drebrin regulates neuroblast migration in the postnatal mammalian brain

Endocannabinoid Turnover

Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain.

Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain

Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists

Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices

Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs

Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis

N-cadherin influences migration of oligodendrocytes on astrocyte monolayers

Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function.

Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless

Nucleofection of rodent neuroblasts to study neuroblast migration in vitro.

Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters.

Overcoming the inhibitors of myelin with a novel neurotrophin strategy

Polysialyltransferase ST8Sia II (STX) polysialylates all of the major isoforms of NCAM and facilitates neurite outgrowth.

RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development

Receptors for myelin inhibitors: Structures and therapeutic opportunities

Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream

Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools; implications for endocannabinoid signaling

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons

Robo1 and Robo2 are homophilic binding molecules that promote axonal growth

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides

The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response

The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation

The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule

The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility.

The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function

The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond

Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11