Lista de obras - Willard M Freeman - Dominio Público Uruguay

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior

artículo científico publicado en 2017

2-D DIGE identification of differentially expressed heterogeneous nuclear ribonucleoproteins and transcription factors during neural differentiation of human embryonic stem cells

artículo científico publicado en 2009

A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis

artículo científico publicado en 2008

A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway

artículo científico publicado en 2000

A multistep validation process of biomarkers for preclinical drug development

artículo científico publicado en 2009

A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes

artículo científico publicado en 2007

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

artículo científico publicado en 2016

Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat.

artículo científico publicado en 2008

Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats.

artículo científico publicado en 2004

Analysis of DNA modifications in aging research.

artículo científico publicado en 2018

Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration

artículo científico publicado en 2006

Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access.

artículo científico publicado en 2015

Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation

scientific article published on 18 April 2016

CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging

artículo científico publicado en 2016

Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression.

artículo científico

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

artículo científico publicado en 2011

Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence

artículo científico publicado en 2011

Circulating cytokines as biomarkers of alcohol abuse and alcoholism

artículo científico publicado en 2009

Classification of alcohol abuse by plasma protein biomarkers

artículo científico publicado en 2010

Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization ⬇️

artículo científico publicado el 22 de noviembre de 2010

Cocaine-responsive gene expression changes in rat hippocampus.

artículo científico publicado en 2001

Cognitive performance and age-related changes in the hippocampal proteome.

artículo científico publicado en 2008

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

artículo científico publicado en 2011

Correlating human and animal studies of cocaine abuse and gene expression.

artículo científico publicado en 2008

Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.

artículo científico publicado en 2015

Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina

artículo científico publicado en 2008

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

artículo científico publicado en 2006

Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex

artículo científico publicado en 2022

Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data

artículo científico publicado en 2012

Distinct proteomic profiles of amphetamine self-administration transitional states.

artículo científico publicado en 2005

Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass

artículo científico publicado en 2010

Early-life DNA methylation profiles are indicative of age-related transcriptome changes

scientific article published on 08 October 2019

Effect of cold perfusion and perfluorocarbons on liver graft ischemia in a donation after cardiac death model

artículo científico publicado en 2014

Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury

artículo científico publicado en 2010

FOXO3a elicits a pro-apoptotic transcription program and cellular response to human lung carcinogen nicotine-derived nitrosaminoketone (NNK).

artículo científico publicado en 2010

Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

artículo científico publicado en 2013

Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy

artículo científico publicado en 2017

Gene expression changes following extinction testing in a heroin behavioral incubation model

artículo científico publicado en 2009

Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration

artículo científico publicado en 2010

Gene expression profiles in HPV-immortalized human cervical cells treated with the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

artículo científico publicado en 2008

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

artículo científico publicado en 2020

Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior

artículo científico publicado en 2008

Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory.

artículo científico publicado en 2012

Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline.

artículo científico publicado en 2014

Improved membrane protein solubilization and clean-up for optimum two-dimensional electrophoresis utilizing GLUT-1 as a classic integral membrane protein.

artículo científico publicado en 2009

Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition.

artículo científico publicado en 2013

Individual differences in hyperlipidemia and vitamin E status in response to chronic alcohol self-administration in cynomolgus monkeys

artículo científico publicado en 2010

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

artículo científico

Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity.

artículo científico publicado en 2002

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats

artículo científico publicado en 2014

Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways

artículo científico publicado en 2014

Isolation of Neuronal Synaptic Membranes by Sucrose Gradient Centrifugation

artículo científico publicado en 2017

Manganese-induced cytotoxicity in dopamine-producing cells

artículo científico publicado en 2004

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

scientific article published on 01 February 2019

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy

artículo científico publicado en 2011

Nanoliposomal minocycline for ocular drug delivery

artículo científico publicado en 2012

Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging

artículo científico publicado en 2012

PCR-based apolipoprotein E genotype analysis from archival fixed brain.

artículo científico

Penn State Hershey--center for pediatric cardiovascular research

artículo científico publicado en 2009

Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.

artículo científico publicado en 2008

Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration.

artículo científico publicado en 2011

Plasma proteomics: a noninvasive window on pathology and pediatric cardiac surgery

scientific article published on 01 September 2006

Protein biomarkers of alcohol abuse.

artículo científico publicado en 2012

Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity

artículo científico publicado en 2012

Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.

artículo científico publicado en 2015

Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression

artículo científico publicado en 2002

Revisiting the genomic hypomethylation hypothesis of aging.

artículo científico publicado en 2018

Reward devaluation and heroin escalation is associated with differential expression of CRF signaling genes

artículo científico publicado en 2015

Role of DNA methylation in the dietary restriction mediated cellular memory.

artículo científico publicado en 2017

Sexually divergent DNA methylation patterns with hippocampal aging

artículo científico publicado en 2017

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

artículo científico publicado en 2017

Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues

scientific article published on 10 May 2019

TPH2 in the ventral tegmental area of the male rat brain

artículo científico publicado en 2011

Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies

artículo científico publicado en 2019

Targeted DNA methylation analysis by next-generation sequencing

artículo científico publicado en 2015

The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions.

artículo científico publicado en 2011

The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome.

artículo científico publicado en 2009

The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.

artículo científico publicado en 2012

The maturation of nucleic acid technologies

artículo científico publicado en 1999

The retinal proteome in experimental diabetic retinopathy: up-regulation of crystallins and reversal by systemic and periocular insulin

artículo científico publicado en 2009

The use of neuroproteomics in drug abuse research

artículo científico publicado en 2010

Transcriptomic comparison of the retina in two mouse models of diabetes

artículo científico publicado en 2009

Twenty-five years of quantitative PCR for gene expression analysis.

scientific article published on April 2008

Tyrosinase mRNA is expressed in human substantia nigra

artículo científico publicado en 1997

Use of microarray technologies in toxicology research.

artículo científico publicado en 2003

Lista de obras de Willard M Freeman

17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior

2-D DIGE identification of differentially expressed heterogeneous nuclear ribonucleoproteins and transcription factors during neural differentiation of human embryonic stem cells

A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis

A cocaine analog, 2beta-propanoyl-3beta-(4-tolyl)-tropane (PTT), reduces tyrosine hydroxylase in the mesolimbic dopamine pathway

A multistep validation process of biomarkers for preclinical drug development

A threshold neurotoxic amphetamine exposure inhibits parietal cortex expression of synaptic plasticity-related genes

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat.

Alterations in ionotropic glutamate receptor subunits during binge cocaine self-administration and withdrawal in rats.

Analysis of DNA modifications in aging research.

Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration

Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access.

Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation

CNS-wide Sexually Dimorphic Induction of the Major Histocompatibility Complex 1 Pathway With Aging

Chronic cocaine-mediated changes in non-human primate nucleus accumbens gene expression.

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence

Circulating cytokines as biomarkers of alcohol abuse and alcoholism

Classification of alcohol abuse by plasma protein biomarkers

Clinical application for the preservation of phospho-proteins through in-situ tissue stabilization ⬇️

Cocaine-responsive gene expression changes in rat hippocampus.

Cognitive performance and age-related changes in the hippocampal proteome.

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

Correlating human and animal studies of cocaine abuse and gene expression.

Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.

Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex

Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data

Distinct proteomic profiles of amphetamine self-administration transitional states.

Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass

Early-life DNA methylation profiles are indicative of age-related transcriptome changes

Effect of cold perfusion and perfluorocarbons on liver graft ischemia in a donation after cardiac death model

Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury

FOXO3a elicits a pro-apoptotic transcription program and cellular response to human lung carcinogen nicotine-derived nitrosaminoketone (NNK).

Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy

Gene expression changes following extinction testing in a heroin behavioral incubation model

Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration

Gene expression profiles in HPV-immortalized human cervical cells treated with the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α

Heroin self-administration: II. CNS gene expression following withdrawal and cue-induced drug-seeking behavior

Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory.

Hippocampal subregions exhibit both distinct and shared transcriptomic responses to aging and nonneurodegenerative cognitive decline.

Improved membrane protein solubilization and clean-up for optimum two-dimensional electrophoresis utilizing GLUT-1 as a classic integral membrane protein.

Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition.

Individual differences in hyperlipidemia and vitamin E status in response to chronic alcohol self-administration in cynomolgus monkeys

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia

Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity.

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats

Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways

Isolation of Neuronal Synaptic Membranes by Sucrose Gradient Centrifugation

Manganese-induced cytotoxicity in dopamine-producing cells

Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy

Nanoliposomal minocycline for ocular drug delivery

Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging

PCR-based apolipoprotein E genotype analysis from archival fixed brain.

Penn State Hershey--center for pediatric cardiovascular research

Plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.

Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration.

Plasma proteomics: a noninvasive window on pathology and pediatric cardiac surgery

Protein biomarkers of alcohol abuse.

Quantification of Hepatic UDP glucuronosyltransferase 1A splice variant expression and correlation of UDP glucuronosyltransferase 1A1 variant expression with glucuronidation activity

Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.

Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression

Revisiting the genomic hypomethylation hypothesis of aging.

Reward devaluation and heroin escalation is associated with differential expression of CRF signaling genes

Role of DNA methylation in the dietary restriction mediated cellular memory.

Sexually divergent DNA methylation patterns with hippocampal aging

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues

TPH2 in the ventral tegmental area of the male rat brain

Tamoxifen induction of Cre recombinase does not cause long-lasting or sexually divergent responses in the CNS epigenome or transcriptome: implications for the design of aging studies

Targeted DNA methylation analysis by next-generation sequencing

The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions.

The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome.

The kinetics of cardiopulmonary bypass: a dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass.

The maturation of nucleic acid technologies