Lista de obras - Anders S Kristensen - Dominio Público Uruguay

2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.

artículo científico publicado en 2003

A Heteromeric Snake Toxin and the Molecular Details of Pain Perception ⬇️

artículo científico publicado el 15 de marzo de 2012

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

artículo científico publicado en 2012

Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization

artículo científico publicado en 2014

Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists

artículo científico publicado en 2010

Binding of ArgTX-636 in the NMDA receptor ion channel

artículo científico publicado en 2014

Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

artículo científico publicado en 2015

Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.

artículo científico publicado en 2004

Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

artículo científico publicado en 2011

Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites.

artículo científico publicado en 2014

Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry

scientific article published on 03 October 2019

Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N-

artículo científico publicado en 2002

Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example.

artículo científico publicado en 2010

Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

artículo científico publicado en 2009

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).

artículo científico publicado en 2003

Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

artículo científico publicado en 2009

Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons.

artículo científico publicado en 2013

Evaluation of PhTX-74 as subtype-selective inhibitor of GluA2-containing AMPA receptors.

artículo científico publicado en 2013

From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies.

artículo científico publicado en 2008

Glutamate receptors: variation in structure-function coupling

artículo científico publicado en 2006

Inhibition of AMPA receptors by polyamine toxins is regulated by agonist efficacy and stargazin

artículo científico publicado en 2014

Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

artículo científico publicado en 2012

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

artículo científico publicado en 2007

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

artículo científico publicado en 2009

Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating ⬇️

artículo científico publicado el 24 de abril de 2011

Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor

artículo científico publicado en 2018

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

artículo científico publicado en 2009

Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (Prozac).

artículo científico publicado en 2014

Molecular cloning, expression and characterization of a bovine serotonin transporter

artículo científico publicado en 1999

Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors

artículo científico publicado en 2019

Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter.

artículo científico publicado en 2009

Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

artículo científico publicado en 2004

Neuroscience: an intrusive chaperone

artículo científico publicado en 2005

On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1.

artículo científico publicado en 2004

Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.

artículo científico publicado en 2014

Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters.

artículo científico publicado en 2009

Small molecules from spiders used as chemical probes.

artículo científico publicado en 2011

Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata.

artículo científico publicado en 2010

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

artículo científico publicado en 2001

Structural rearrangement of the intracellular domains during AMPA receptor activation

artículo científico publicado en 2016

Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors

artículo científico publicado en 2014

Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors

artículo científico publicado en 2013

Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the 5-HT transporter

artículo científico

Substrate and Inhibitor-Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry.

artículo científico publicado en 2015

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

artículo científico publicado en 2007

Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

artículo científico publicado en 2009

Targeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein family

artículo científico publicado en 2015

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

artículo científico publicado en 2009

The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.

artículo científico publicado en 2006

Lista de obras de Anders S Kristensen

2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.

A Heteromeric Snake Toxin and the Molecular Details of Pain Perception ⬇️

A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization

Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists

Binding of ArgTX-636 in the NMDA receptor ion channel

Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.

Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

Characterization of intracellular regions in the human serotonin transporter for phosphorylation sites.

Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry

Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N-

Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example.

Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).

Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons.

Evaluation of PhTX-74 as subtype-selective inhibitor of GluA2-containing AMPA receptors.

From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies.

Glutamate receptors: variation in structure-function coupling

Inhibition of AMPA receptors by polyamine toxins is regulated by agonist efficacy and stargazin

Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket

Ionotropic glutamate-like receptor 2 binds D-serine and glycine

Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants.

Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating ⬇️

Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor

Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium

Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (Prozac).

Molecular cloning, expression and characterization of a bovine serotonin transporter

Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors

Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter.

Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

Neuroscience: an intrusive chaperone

On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1.

Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations.

Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters.

Small molecules from spiders used as chemical probes.

Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata.

Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

Structural rearrangement of the intracellular domains during AMPA receptor activation

Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors

Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors

Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the 5-HT transporter

Substrate and Inhibitor-Specific Conformational Changes in the Human Serotonin Transporter Revealed by Voltage-Clamp Fluorometry.

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

Targeting protein-protein interactions with trimeric ligands: high affinity inhibitors of the MAGUK protein family

The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.