Lista de obras - Martin Giera - Dominio Público Uruguay

A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis

artículo científico publicado en 2013

A gas chromatography-mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis

scientific article published on 24 July 2019

A hypomorphic Cbx3 allele causes prenatal growth restriction and perinatal energy homeostasis defects

artículo científico publicado en 2015

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

scientific article published on 17 July 2018

Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in mice

artículo científico publicado en 2016

Adipocyte-derived lipids modulate CD4+ T-cell function

artículo científico publicado en 2013

Adipocytes modulate the phenotype of human macrophages through secreted lipids

artículo científico publicado en 2013

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures

artículo científico publicado en 2010

Amino acid analysis using chromatography-mass spectrometry: An inter platform comparison study

artículo científico publicado en 2015

Analysis of acetylcholinesterase inhibitors: bioanalysis, degradation and metabolism.

artículo científico publicado en 2010

Analysis of biologically-active, endogenous carboxylic acids based on chromatography-mass spectrometry

Analytical pitfalls and challenges in clinical metabolomics.

artículo científico publicado en 2016

Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid

scientific article published on 02 October 2020

Antifungal drug testing by combining minimal inhibitory concentration testing with target identification by gas chromatography-mass spectrometry.

artículo científico publicado en 2017

Automated quantification of metabolites in blood-derived samples by NMR.

artículo científico publicado en 2017

Bioanalytical derivatization: is there still room for development?

artículo científico publicado en 2015

Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes

artículo científico publicado en 2022

Comparison of (bio-)transformation methods for the generation of metabolite-like compound libraries of p38α MAP kinase inhibitors using high-resolution screening.

artículo científico publicado en 2013

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol

artículo científico publicado en 2019

Comprehensive gas chromatography-electron ionisation mass spectrometric analysis of fatty acids and sterols using sequential one-pot silylation: quantification and isotopologue analysis.

artículo científico publicado en 2014

Derivatization of carboxylic acids with 4-APEBA for detection by positive-ion LC-ESI-MS(/MS) applied for the analysis of prostanoids and NSAID in urine

scientific article published on 03 December 2010

Derivatization of the tricarboxylic acid cycle intermediates and analysis by online solid-phase extraction-liquid chromatography-mass spectrometry with positive-ion electrospray ionization

artículo científico publicado en 2011

Detection and Structural Elucidation of Esterified Oxylipids in Human Synovial Fluid by Electrospray Ionization-Fourier Transform Ion-Cyclotron Mass Spectrometry and Liquid Chromatography-Ion Trap-MS3: Detection of Esterified Hydroxylated Docosapenta

artículo científico publicado en 2013

Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays

artículo científico publicado en 2010

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.

artículo científico publicado en 2010

Differential Mobility Separation of Leukotrienes and Protectins

article

Evaluation of different column chemistries for fast urinary metabolic profiling

artículo científico publicado en 2013

F2-Isoprostanes in HDL are bound to neutral lipids and phospholipids

artículo científico publicado en 2016

Fast and easy in vitro screening assay for cholesterol biosynthesis inhibitors in the post-squalene pathway

artículo científico publicado en 2007

Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37

artículo científico publicado en 2022

Fungal sterol C22-desaturase is not an antimycotic target as shown by selective inhibitors and testing on clinical isolates.

artículo científico publicado en 2015

Glutathione Metabolism Contributes to the Induction of Trained Immunity

artículo científico publicado en 2021

Haloperidol disrupts lipid rafts and impairs insulin signaling in SH-SY5Y cells

artículo científico publicado en 2010

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites

artículo científico publicado en 2011

Identification and quantification of drug-albumin adducts in serum samples from a drug exposure study in mice

artículo científico publicado en 2013

Identification of bioactive metabolites using activity metabolomics

artículo científico publicado en 2019

Identification of the Biotransformation Products of 2-Ethylhexyl 4-(N,N-Dimethylamino)benzoate

artículo científico publicado en 2009

Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes.

artículo científico publicado en 2015

Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.

artículo científico publicado en 2009

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration

artículo científico publicado en 2018

Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution

artículo científico publicado en 2019

Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25years of research in chemistry and biology.

artículo científico publicado en 2017

KIMBLE: A versatile visual NMR metabolomics workbench in KNIME

artículo científico publicado en 2018

Krill Oil Treatment Increases Distinct PUFAs and Oxylipins in Adipose Tissue and Liver and Attenuates Obesity-Associated Inflammation via Direct and Indirect Mechanisms

artículo científico publicado en 2021

Lathosterol side chain amides: a new class of human lathosterol oxidase inhibitors

artículo científico publicado en 2007

Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure σ ligands with 2-benzopyran structure

artículo científico publicado en 2017

Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS

artículo científico publicado en 2012

Lipid metabolism of leukocytes in the unstimulated and activated states

artículo científico publicado en 2020

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

artículo científico publicado en 2022

Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice

artículo científico publicado en 2021

Microfractionation revisited: a 1536 well high resolution screening assay.

artículo científico publicado en 2009

Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels

artículo científico publicado en 2011

Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood

artículo científico publicado en 2006

New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase.

artículo científico publicado en 2017

On-line electrochemical reduction of disulfide bonds: improved FTICR-CID and -ETD coverage of oxytocin and hepcidin.

artículo científico publicado en 2013

On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.

artículo científico publicado en 2012

Photohuperzine A-A new photoisomer of huperzine A: structure elucidation, formation kinetics and activity assessment

artículo científico publicado en 2010

Probing the genome-scale metabolic landscape of Bordetella pertussis, the causative agent of whooping cough.

artículo científico

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile.

artículo científico publicado en 2014

Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect?

artículo científico publicado en 2015

Protein digestion optimization for characterization of drug-protein adducts using response surface modeling

artículo científico publicado en 2010

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

artículo científico publicado en 2018

Quantitative NMR analysis of intra- and extracellular metabolism of mammalian cells: A tutorial

artículo científico publicado en 2017

Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview.

artículo científico

Recent advances in liquid-phase separations for clinical metabolomics

artículo científico publicado en 2016

Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons

artículo científico publicado en 2021

Reproducibility of Targeted Lipidome Analyses (Lipidyzer) in Plasma and Erythrocytes over a 6-Week Period

artículo científico publicado en 2020

Scientific workflow managers in metabolomics: an overview

scientific article published on 06 May 2020

Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis

artículo científico publicado en 2009

Stability-indicating study of the anti-Alzheimer's drug galantamine hydrobromide.

artículo científico publicado en 2011

Structural elucidation of biologically active neomycin N-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry

artículo científico publicado en 2010

Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A

scientific article published in Nature Communications

Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.

artículo científico publicado en 2017

The Schistosoma mansoni lipidome: Leads for immunomodulation

artículo científico publicado en 2017

The neuroimmune guidance cue netrin-1 controls resolution programs and promotes liver regeneration.

artículo científico publicado en 2016

The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice

scientific article published in Scientific Reports

The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells

artículo científico publicado en 2016

Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension

scientific article published on 20 February 2020

William Griffiths, Yuqin Wang (Eds.): Lipidomics: current and emerging techniques

artículo científico publicado en 2020

Lista de obras de Martin Giera

A convenient cellular assay for the identification of the molecular target of ergosterol biosynthesis inhibitors and quantification of their effects on total ergosterol biosynthesis

A gas chromatography-mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis

A hypomorphic Cbx3 allele causes prenatal growth restriction and perinatal energy homeostasis defects

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation

Acute phase inflammation is characterized by rapid changes in plasma/peritoneal fluid N-glycosylation in mice

Adipocyte-derived lipids modulate CD4+ T-cell function

Adipocytes modulate the phenotype of human macrophages through secreted lipids

Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures

Amino acid analysis using chromatography-mass spectrometry: An inter platform comparison study

Analysis of acetylcholinesterase inhibitors: bioanalysis, degradation and metabolism.

Analysis of biologically-active, endogenous carboxylic acids based on chromatography-mass spectrometry

Analytical pitfalls and challenges in clinical metabolomics.

Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid

Antifungal drug testing by combining minimal inhibitory concentration testing with target identification by gas chromatography-mass spectrometry.

Automated quantification of metabolites in blood-derived samples by NMR.

Bioanalytical derivatization: is there still room for development?

Bone marrow transplantation induces changes in the gut microbiota that chronically increase the cytokine response pattern of splenocytes

Comparison of (bio-)transformation methods for the generation of metabolite-like compound libraries of p38α MAP kinase inhibitors using high-resolution screening.

Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol

Comprehensive gas chromatography-electron ionisation mass spectrometric analysis of fatty acids and sterols using sequential one-pot silylation: quantification and isotopologue analysis.

Derivatization of carboxylic acids with 4-APEBA for detection by positive-ion LC-ESI-MS(/MS) applied for the analysis of prostanoids and NSAID in urine

Derivatization of the tricarboxylic acid cycle intermediates and analysis by online solid-phase extraction-liquid chromatography-mass spectrometry with positive-ion electrospray ionization

Detection and Structural Elucidation of Esterified Oxylipids in Human Synovial Fluid by Electrospray Ionization-Fourier Transform Ion-Cyclotron Mass Spectrometry and Liquid Chromatography-Ion Trap-MS3: Detection of Esterified Hydroxylated Docosapenta

Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays

Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS.

Differential Mobility Separation of Leukotrienes and Protectins

Evaluation of different column chemistries for fast urinary metabolic profiling

F2-Isoprostanes in HDL are bound to neutral lipids and phospholipids

Fast and easy in vitro screening assay for cholesterol biosynthesis inhibitors in the post-squalene pathway

Fatty acid metabolism in aggressive B-cell lymphoma is inhibited by tetraspanin CD37

Fungal sterol C22-desaturase is not an antimycotic target as shown by selective inhibitors and testing on clinical isolates.

Glutathione Metabolism Contributes to the Induction of Trained Immunity

Haloperidol disrupts lipid rafts and impairs insulin signaling in SH-SY5Y cells

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites

Identification and quantification of drug-albumin adducts in serum samples from a drug exposure study in mice

Identification of bioactive metabolites using activity metabolomics

Identification of the Biotransformation Products of 2-Ethylhexyl 4-(N,N-Dimethylamino)benzoate

Increased PUFA Content and 5-Lipoxygenase Pathway Expression Are Associated with Subcutaneous Adipose Tissue Inflammation in Obese Women with Type 2 Diabetes.

Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes.

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration

Inhibition of Δ24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution

Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25years of research in chemistry and biology.

KIMBLE: A versatile visual NMR metabolomics workbench in KNIME

Krill Oil Treatment Increases Distinct PUFAs and Oxylipins in Adipose Tissue and Liver and Attenuates Obesity-Associated Inflammation via Direct and Indirect Mechanisms

Lathosterol side chain amides: a new class of human lathosterol oxidase inhibitors

Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure σ ligands with 2-benzopyran structure

Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS

Lipid metabolism of leukocytes in the unstimulated and activated states

Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice

Microfractionation revisited: a 1536 well high resolution screening assay.

Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels

Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood

New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase.

On-line electrochemical reduction of disulfide bonds: improved FTICR-CID and -ETD coverage of oxytocin and hepcidin.

On-line electrochemistry-bioaffinity screening with parallel HR-LC-MS for the generation and characterization of modified p38α kinase inhibitors.

Photohuperzine A-A new photoisomer of huperzine A: structure elucidation, formation kinetics and activity assessment

Probing the genome-scale metabolic landscape of Bordetella pertussis, the causative agent of whooping cough.

Prolonged niacin treatment leads to increased adipose tissue PUFA synthesis and anti-inflammatory lipid and oxylipin plasma profile.

Protein costs do not explain evolution of metabolic strategies and regulation of ribosomal content: does protein investment explain an anaerobic bacterial Crabtree effect?

Protein digestion optimization for characterization of drug-protein adducts using response surface modeling

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans

Proteomic identification of Axc, a novel beta-lactamase with carbapenemase activity in a meropenem-resistant clinical isolate of Achromobacter xylosoxidans.

Quantitative NMR analysis of intra- and extracellular metabolism of mammalian cells: A tutorial

Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview.

Recent advances in liquid-phase separations for clinical metabolomics

Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons

Reproducibility of Targeted Lipidome Analyses (Lipidyzer) in Plasma and Erythrocytes over a 6-Week Period

Scientific workflow managers in metabolomics: an overview

Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis

Stability-indicating study of the anti-Alzheimer's drug galantamine hydrobromide.

Structural elucidation of biologically active neomycin N-octyl derivatives in a regioisomeric mixture by means of liquid chromatography/ion trap time-of-flight mass spectrometry

Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A

Targeted lipidomics reveals activation of resolution pathways in knee osteoarthritis in humans.

The Schistosoma mansoni lipidome: Leads for immunomodulation

The neuroimmune guidance cue netrin-1 controls resolution programs and promotes liver regeneration.

The prebiotic inulin modulates gut microbiota but does not ameliorate atherosclerosis in hypercholesterolemic APOE*3-Leiden.CETP mice

The whipworm (Trichuris suis) secretes prostaglandin E2 to suppress proinflammatory properties in human dendritic cells

Trans-right ventricle and transpulmonary metabolite gradients in human pulmonary arterial hypertension