Lista de obras - Monica Borgatti - Dominio Público Uruguay

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

article

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

scientific article published on 05 April 2020

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

artículo científico publicado en 2022

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

artículo científico publicado en 2012

Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin

artículo científico publicado en 2003

Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.

artículo científico

Anti-inflammatory effect of miglustat in bronchial epithelial cells.

artículo científico publicado en 2008

Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis

artículo científico publicado en 2014

Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells

artículo científico publicado en 2011

Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine.

artículo científico publicado en 2006

Apoptosis of human primary osteoclasts treated with molecules targeting nuclear factor-kappaB.

artículo científico publicado en 2009

Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.

artículo científico publicado en 2001

Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

artículo científico publicado en 2011

Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.

artículo científico publicado en 2009

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

artículo científico publicado en 2004

Biosensor Technology and Surface Plasmon Resonance for Real-Time Detection of Genetically Modified Roundup Ready Soybean Gene Sequences

article

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

artículo científico publicado en 2011

Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors

artículo científico publicado en 2002

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells

artículo científico publicado en 2012

Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties.

artículo científico publicado en 2005

Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor

scientific article published on 01 October 2019

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

artículo científico publicado en 2009

Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects

artículo científico publicado el 23 de julio de 2011

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

artículo científico publicado en 2017

Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives.

artículo científico publicado en 2009

Direct detection of point mutations in nonamplified human genomic DNA.

artículo científico publicado en 2011

Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening

artículo científico publicado en 2020

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

artículo científico publicado en 2008

Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release

artículo científico publicado en 2013

Effects of biomaterials for Lab-on-a-chip production on cell growth and expression of differentiated functions of leukemic cell lines.

artículo científico publicado en 2010

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.

artículo científico publicado en 2006

Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin

artículo científico publicado en 2015

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

artículo científico

Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.

artículo científico publicado en 2010

Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.

artículo científico publicado en 2006

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

artículo científico publicado en 2014

Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions.

artículo científico publicado en 2014

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

scientific article published on 11 December 2007

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

artículo científico publicado en 2015

In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa

artículo científico publicado en 2003

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

artículo científico publicado en 2009

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

artículo científico publicado en 2015

Induction by TNF-α of IL-6 and IL-8 in cystic fibrosis bronchial IB3-1 epithelial cells encapsulated in alginate microbeads

artículo científico publicado en 2010

Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis

artículo científico publicado en 2008

Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules.

artículo científico publicado en 2006

Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.

artículo científico publicado en 2007

Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences

artículo científico publicado en 2008

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

artículo científico publicado en 1999

Involvement of miRNA in erythroid differentiation

artículo científico

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

artículo científico publicado en 2011

Levitation and movement of human tumor cells using a printed circuit board device based on software-controlled dielectrophoresis

artículo científico publicado en 2003

Levitation and movement of tripalmitin‐based cationic lipospheres on a dielectrophoresis‐based lab‐on‐a‐chip device

Lysis-on-chip of single target cells following forced interaction with CTLs or NK cells on a dielectrophoresis-based array

artículo científico publicado en 2013

MPB-07 Reduces the Inflammatory Response toPseudomonas aeruginosain Cystic Fibrosis Bronchial Cells

artículo científico publicado en 2006

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

artículo científico publicado en 2011

Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages.

artículo científico publicado en 2006

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water ⬇️

artículo científico publicado el 7 de julio de 2013

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

artículo científico publicado en 2011

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

artículo científico

NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells

artículo científico publicado en 2010

New uracil dimers showing erythroid differentiation inducing activities.

artículo científico publicado en 2009

Non-invasive Prenatal Testing Using Fetal DNA

artículo científico publicado en 2019

Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR.

artículo científico publicado en 2018

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

artículo científico publicado en 2012

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

artículo científico publicado en 2014

Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays

artículo científico publicado en 2017

Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O-isopropylidene-D-mannofuranose.

artículo científico publicado en 2002

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

artículo científico publicado en 2009

Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip

artículo científico publicado en 2013

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

artículo científico publicado en 2013

Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells

artículo científico publicado en 2008

Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.

artículo científico publicado en 2004

Release of sICAM-1 in oocytes and in vitro fertilized human embryos

artículo científico publicado en 2008

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

artículo científico publicado en 2012

Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia

scientific article published on 21 January 2020

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

artículo científico publicado en 2008

Surface plasmon resonance analysis to detect the β+IVSI-110 thalassemia mutation in circulating cell-free fetal DNA.

artículo científico publicado en 2016

Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.

artículo científico publicado en 2005

Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents

artículo científico publicado en 2006

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

artículo científico

The loss of cellular junctions in epithelial lung cells induced by cigarette smoke is attenuated by corilagin

artículo científico publicado en 2015

Tobramycin is a suppressor of premature termination codons

artículo científico publicado en 2013

Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites

artículo científico publicado en 2002

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

artículo científico publicado en 2010

UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

artículo científico publicado en 2018

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

artículo científico publicado en 2014

Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κB dependent biological functions involved in cystic fibrosis.

artículo científico publicado en 2010

Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes.

artículo científico publicado en 2009

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

artículo científico publicado en 2016

gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions

artículo científico publicado en 2010

mTOR and STAT3 Pathway Hyper-Activation is Associated with evated Interleukin-6 Levels in Patients with Shwachman-Diamond Syndrome: Further Evidence of Lymphoid Lineage Impairment

artículo científico publicado en 2020

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

artículo científico

Lista de obras de Monica Borgatti

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction

Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin

Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.

Anti-inflammatory effect of miglustat in bronchial epithelial cells.

Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis

Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells

Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine.

Apoptosis of human primary osteoclasts treated with molecules targeting nuclear factor-kappaB.

Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.

Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines.

Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

Biosensor Technology and Surface Plasmon Resonance for Real-Time Detection of Genetically Modified Roundup Ready Soybean Gene Sequences

C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells

Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties.

Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

Development of a novel furocoumarin derivative inhibiting NF-κB dependent biological functions: design, synthesis and biological effects

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives.

Direct detection of point mutations in nonamplified human genomic DNA.

Discovery of Novel Fetal Hemoglobin Inducers through Small Chemical Library Screening

Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression

Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release

Effects of biomaterials for Lab-on-a-chip production on cell growth and expression of differentiated functions of leukemic cell lines.

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.

Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen.

Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions.

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

Induction by TNF-α of IL-6 and IL-8 in cystic fibrosis bronchial IB3-1 epithelial cells encapsulated in alginate microbeads

Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis

Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules.

Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives.

Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences

Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter.

Involvement of miRNA in erythroid differentiation

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

Levitation and movement of human tumor cells using a printed circuit board device based on software-controlled dielectrophoresis

Levitation and movement of tripalmitin‐based cationic lipospheres on a dielectrophoresis‐based lab‐on‐a‐chip device

Lysis-on-chip of single target cells following forced interaction with CTLs or NK cells on a dielectrophoresis-based array

MPB-07 Reduces the Inflammatory Response toPseudomonas aeruginosain Cystic Fibrosis Bronchial Cells

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages.

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water ⬇️

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites

NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells

New uracil dimers showing erythroid differentiation inducing activities.

Non-invasive Prenatal Testing Using Fetal DNA

Non-invasive fetal sex diagnosis in plasma of early weeks pregnants using droplet digital PCR.

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays

Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O-isopropylidene-D-mannofuranose.

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells

Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.

Release of sICAM-1 in oocytes and in vitro fertilized human embryos

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

Screening Readthrough Compounds to Suppress Nonsense Mutations: Possible Application to β-Thalassemia

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

Surface plasmon resonance analysis to detect the β+IVSI-110 thalassemia mutation in circulating cell-free fetal DNA.

Synthesis and biological activity of alpha-bromoacryloyl lexitropsin conjugates.