Lista de obras - Loretta Lazzarato - Dominio Público Uruguay

(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins

artículo científico publicado en 2009

A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light.

artículo científico publicado en 2017

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

artículo científico publicado en 2016

A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light

artículo científico publicado en 2018

A new class of ibuprofen derivatives with reduced gastrotoxicity

artículo científico publicado en 2001

A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion

artículo científico publicado en 2015

A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages

artículo científico publicado en 2008

A rapid screening for cytochrome P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives

artículo científico publicado en 2012

Aceclofenac–Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations

artículo científico publicado en 2018

Amphiphilic NO-Donor Antioxidants

artículo científico publicado en 2007

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin

artículo científico publicado en 2003

Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors?

artículo científico publicado en 2020

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

artículo científico publicado en 2011

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

scientific article published on 07 November 2019

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

scholarly article by Massimo Bertinaria et al published 26 November 2012 in ChemMedChem

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

scientific article published on 31 March 2022

Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells

scientific article published on 09 January 2019

Design, Synthesis and Characterization of N-oxide-containing Heterocycles with In vivo Sterilizing Antitubercular Activity.

artículo científico publicado en 2017

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

artículo científico publicado en 2012

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.

artículo científico publicado en 2004

Doxorubicin-antioxidant co-drugs

artículo científico publicado en 2013

Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents

artículo científico publicado en 2014

Furoxan Nitric Oxide Donors Disperse Pseudomonas aeruginosa Biofilms, Accelerate Growth, and Repress Pyoverdine Production

artículo científico publicado en 2017

Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis.

artículo científico publicado en 2017

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

artículo científico publicado en 2016

Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells.

artículo científico publicado en 2015

Mechanistic insights into cyclooxygenase irreversible inactivation by aspirin.

artículo científico publicado en 2009

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

artículo científico publicado en 2019

Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonate

article

Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance

artículo científico publicado en 2012

Multitarget drugs: Focus on the NO-donor hybrid drugs

NO release regulated by doxorubicin as the green light-harvesting antenna

scientific article published on 21 May 2020

NO-Donor COX-2 Inhibitors. New Nitrooxy-Substituted 1,5-Diarylimidazoles Endowed with COX-2 Inhibitory and Vasodilator Properties

scientific article published on 03 March 2007

NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties

scientific article published on 01 May 2006

NO-donor melatonin derivatives: synthesis and in vitro pharmacological characterization

artículo científico publicado en 2007

New Nitric Oxide or Hydrogen Sulfide Releasing Aspirins

artículo científico publicado en 2011

New furoxan derivatives for the treatment of ocular hypertension

artículo científico publicado en 2016

Nitric oxide donor doxorubicins accumulate into Doxorubicin-resistant human colon cancer cells inducing cytotoxicity

artículo científico publicado en 2011

Nitrooxyacyl derivatives of salicylic acid: aspirin-like molecules that covalently inactivate cyclooxygenase-1.

artículo científico publicado en 2011

Nitrooxymethyl-substituted analogues of celecoxib: synthesis and pharmacological characterization

artículo científico publicado en 2009

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties

artículo científico publicado en 2008

Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug

artículo científico publicado en 2019

Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates

artículo científico publicado en 2010

Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans

artículo científico publicado en 2011

Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid

artículo científico publicado en 2008

Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors.

artículo científico publicado en 2017

Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4'-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Sel

artículo científico publicado en 2016

Structure-antioxidant activity relationships in a series of NO-donor phenols

artículo científico publicado en 2008

Studies of the potential genotoxic effects of furoxans: the case of CAS 1609 and of the water-soluble analogue of CHF 2363.

artículo científico publicado en 2008

Synthesis and Biological Evaluation of the First Example of NO-Donor Histone Deacetylase Inhibitor

artículo científico publicado en 2013

Synthesis and antimalarial activities of some furoxan sulfones and related furazans.

artículo científico publicado en 2005

Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis.

artículo científico publicado en 2016

Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues

artículo científico publicado en 2012

Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs).

artículo científico publicado en 2010

Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.

artículo científico publicado en 2005

Synthesis of some novel organic nitrates and comparative in vitro study of their vasodilator profile

artículo científico publicado en 2009

Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs

scientific article published on 08 December 2011

Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers

artículo científico publicado en 2006

The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX-2 Endowed with Anti-Aggregatory and Vasodilating Activities

artículo científico publicado en 2005

Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor

artículo científico publicado en 2018

Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid (ASA) Prodrugs

artículo científico publicado en 2013

gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension.

artículo científico publicado en 2017

Lista de obras de Loretta Lazzarato

(Nitrooxyacyloxy)methyl esters of aspirin as novel nitric oxide releasing aspirins

A Nonmetal-Containing Nitric Oxide Donor Activated with Single-Photon Green Light.

A Potent and Selective P-gp Modulator for Altering Multidrug Resistance Due to Pump Overexpression.

A molecular hybrid producing simultaneously singlet oxygen and nitric oxide by single photon excitation with green light

A new class of ibuprofen derivatives with reduced gastrotoxicity

A nitric oxide-donor furoxan moiety improves the efficacy of edaravone against early renal dysfunction and injury evoked by ischemia/reperfusion

A novel hybrid aspirin-NO-releasing compound inhibits TNFalpha release from LPS-activated human monocytes and macrophages

A rapid screening for cytochrome P450 catalysis on new chemical entities: cytochrome P450 BM3 and 1,2,5-oxadiazole derivatives

Aceclofenac–Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations

Amphiphilic NO-Donor Antioxidants

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin

Can We Exploit β-Lactamases Intrinsic Dynamics for Designing More Effective Inhibitors?

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

Combination of PDT and NOPDT with a Tailored BODIPY Derivative

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction

Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells

Design, Synthesis and Characterization of N-oxide-containing Heterocycles with In vivo Sterilizing Antitubercular Activity.

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.

Doxorubicin-antioxidant co-drugs

Furazan and furoxan sulfonamides are strong α-carbonic anhydrase inhibitors and potential antiglaucoma agents

Furoxan Nitric Oxide Donors Disperse Pseudomonas aeruginosa Biofilms, Accelerate Growth, and Repress Pyoverdine Production

Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis.

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells.

Mechanistic insights into cyclooxygenase irreversible inactivation by aspirin.

Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

Michael addition of Grignard reagents to tetraethyl ethenylidenebisphosphonate

Mitochondrial-targeting nitrooxy-doxorubicin: a new approach to overcome drug resistance

Multitarget drugs: Focus on the NO-donor hybrid drugs

NO release regulated by doxorubicin as the green light-harvesting antenna

NO-Donor COX-2 Inhibitors. New Nitrooxy-Substituted 1,5-Diarylimidazoles Endowed with COX-2 Inhibitory and Vasodilator Properties

NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties

NO-donor melatonin derivatives: synthesis and in vitro pharmacological characterization

New Nitric Oxide or Hydrogen Sulfide Releasing Aspirins

New furoxan derivatives for the treatment of ocular hypertension

Nitric oxide donor doxorubicins accumulate into Doxorubicin-resistant human colon cancer cells inducing cytotoxicity

Nitrooxyacyl derivatives of salicylic acid: aspirin-like molecules that covalently inactivate cyclooxygenase-1.

Nitrooxymethyl-substituted analogues of celecoxib: synthesis and pharmacological characterization

Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties

Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug

Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates

Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans

Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid

Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors.

Structure-Activity Relationship Studies on Tetrahydroisoquinoline Derivatives: [4'-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol] (MC70) Conjugated through Flexible Alkyl Chains with Furazan Moieties Gives Rise to Potent and Sel

Structure-antioxidant activity relationships in a series of NO-donor phenols

Studies of the potential genotoxic effects of furoxans: the case of CAS 1609 and of the water-soluble analogue of CHF 2363.

Synthesis and Biological Evaluation of the First Example of NO-Donor Histone Deacetylase Inhibitor

Synthesis and antimalarial activities of some furoxan sulfones and related furazans.

Synthesis and biological activity of furoxan derivatives against Mycobacterium tuberculosis.

Synthesis and preliminary biological profile of new NO-donor tolbutamide analogues

Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs).

Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.

Synthesis of some novel organic nitrates and comparative in vitro study of their vasodilator profile

Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs

Synthesis, chiral HPLC resolution and configuration assignment of 1-phenylglyceryl trinitrate stereomers

The Furoxan System: Design of Selective Nitric Oxide (NO) Donor Inhibitors of COX-2 Endowed with Anti-Aggregatory and Vasodilating Activities

Tuning the Hydrophobicity of a Mitochondria-Targeted NO Photodonor

Water-Soluble Nitric-Oxide-Releasing Acetylsalicylic Acid (ASA) Prodrugs

gem-Dinitroalkyl Benzenes: A Novel Class of IOP-Lowering Agents for the Treatment of Ocular Hypertension.