Lista de obras - Tomasz Fraczyk - Dominio Público Uruguay

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

artículo científico publicado en 2015

Altered mouse leukemia L1210 thymidylate synthase, associated with cell resistance to 5-fluoro-dUrd, is not mutated but rather reflects posttranslational modification

artículo científico publicado en 2006

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

artículo científico

Cu(II)‐Binding N‐Terminal Sequences of Human Proteins

artículo científico publicado en 2021

Design and in vitro Characterization of Tricyclic Benzodiazepine Derivatives as Potent and Selective Anti-leukemic Agents

artículo científico publicado en 2020

Developmental arrest in Caenorhabditis elegans dauer larvae causes high expression of enzymes involved in thymidylate biosynthesis, similar to that found in Trichinella muscle larvae.

artículo científico publicado en 2005

Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules

artículo científico publicado en 2004

Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action of melatonin and N-acetylcysteine

artículo científico publicado en 2004

Effect of enzymatic hydrolysis on surface activity and surface rheology of type I collagen

scientific article published on 19 May 2015

Effect of surfactants on surface activity and rheological properties of type I collagen at air/water interface

artículo científico publicado en 2016

Electron capture dissociation mass spectrometric analysis of lysine-phosphorylated peptides.

artículo científico publicado en 2010

Gly-His-Thr-Asp-Amide, an Insulin-Activating Peptide from the Human Pancreas Is a Strong Cu(II) but a Weak Zn(II) Chelator

scientific article published on 27 November 2018

Human annexins A1, A2, and A8 as potential molecular targets for Ni(II) ions.

artículo científico publicado en 2014

Interplay between Copper, Neprilysin, and N-Truncation of β-Amyloid

scientific article published on 18 May 2018

Mechanism of influence of phosphorylation on serine 124 on a decrease of catalytic activity of human thymidylate synthase

artículo científico publicado en 2010

Melatonin attenuates diabetes-induced oxidative stress in rabbits

artículo científico publicado en 2006

Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme

New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8.

artículo científico publicado en 2016

Ni(ii) ions cleave and inactivate human alpha-1 antitrypsin hydrolytically, implicating nickel exposure as a contributing factor in pathologies related to antitrypsin deficiency

artículo científico publicado en 2015

On the ability of CuAβ1-x peptides to form ternary complexes: Neurotransmitter glutamate is a competitor while not a ternary partner

artículo científico publicado en 2016

Peptide Bond Cleavage by Ni(II) Ions within the Nuclear Localization Signal Sequence

artículo científico publicado en 2020

Peptide bond cleavage in the presence of Ni-containing particles

scientific article published on 12 May 2020

Phosphorylation of basic amino acid residues in proteins: important but easily missed

artículo científico publicado el 27 de mayo de 2011

Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N(4)-hydroxy-dCMP.

artículo científico publicado en 2016

Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits

artículo científico publicado en 2010

Properties of phosphorylated thymidylate synthase

scientific journal article

Revised coordination model and stability constants of Cu(II) complexes of tris buffer

artículo científico publicado en 2013

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate

scientific article published on 27 August 2020

The Palladium(II) Complex of A<i>β</i><sub>4-16</sub> as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids

artículo científico publicado en 2020

The Sub-picomolar Cu2+ Dissociation Constant of Human Serum Albumin

artículo científico publicado en 2019

Thiophosphorylation of free amino acids and enzyme protein by thiophosphoramidate ions

artículo científico publicado en 2009

Thymidylate synthase-catalyzed, tetrahydrofolate-dependent self-inactivation by 5-FdUMP

scientific article published on 11 September 2019

Tyrosine nitration affects thymidylate synthase properties.

artículo científico publicado en 2011

Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose)Polymerase 1 (PARP-1) Nuclear Protein

artículo científico publicado en 2014

cis-Urocanic acid as a potential nickel(II) binding molecule in the human skin

artículo científico publicado en 2014

Lista de obras de Tomasz Fraczyk

A Functional Role for Aβ in Metal Homeostasis? N-Truncation and High-Affinity Copper Binding.

Altered mouse leukemia L1210 thymidylate synthase, associated with cell resistance to 5-fluoro-dUrd, is not mutated but rather reflects posttranslational modification

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

Cu(II)‐Binding N‐Terminal Sequences of Human Proteins

Design and in vitro Characterization of Tricyclic Benzodiazepine Derivatives as Potent and Selective Anti-leukemic Agents

Developmental arrest in Caenorhabditis elegans dauer larvae causes high expression of enzymes involved in thymidylate biosynthesis, similar to that found in Trichinella muscle larvae.

Diabetes-induced changes in glucose synthesis, intracellular glutathione status and hydroxyl free radical generation in rabbit kidney-cortex tubules

Differential effects of vanadium, tungsten and molybdenum on inhibition of glucose formation in renal tubules and hepatocytes of control and diabetic rabbits: beneficial action of melatonin and N-acetylcysteine

Effect of enzymatic hydrolysis on surface activity and surface rheology of type I collagen

Effect of surfactants on surface activity and rheological properties of type I collagen at air/water interface

Electron capture dissociation mass spectrometric analysis of lysine-phosphorylated peptides.

Gly-His-Thr-Asp-Amide, an Insulin-Activating Peptide from the Human Pancreas Is a Strong Cu(II) but a Weak Zn(II) Chelator

Human annexins A1, A2, and A8 as potential molecular targets for Ni(II) ions.

Interplay between Copper, Neprilysin, and N-Truncation of β-Amyloid

Mechanism of influence of phosphorylation on serine 124 on a decrease of catalytic activity of human thymidylate synthase

Melatonin attenuates diabetes-induced oxidative stress in rabbits

Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme

New insights into interactions between the nucleotide-binding domain of CFTR and keratin 8.

Ni(ii) ions cleave and inactivate human alpha-1 antitrypsin hydrolytically, implicating nickel exposure as a contributing factor in pathologies related to antitrypsin deficiency

On the ability of CuAβ1-x peptides to form ternary complexes: Neurotransmitter glutamate is a competitor while not a ternary partner

Peptide Bond Cleavage by Ni(II) Ions within the Nuclear Localization Signal Sequence

Peptide bond cleavage in the presence of Ni-containing particles

Phosphorylation of basic amino acid residues in proteins: important but easily missed

Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N(4)-hydroxy-dCMP.

Phosphorylation of thymidylate synthase from various sources by human protein kinase CK2 and its catalytic subunits

Properties of phosphorylated thymidylate synthase

Revised coordination model and stability constants of Cu(II) complexes of tris buffer

Ternary Cu(II) Complex with GHK Peptide and Cis-Urocanic Acid as a Potential Physiologically Functional Copper Chelate

The Palladium(II) Complex of A<i>β</i><sub>4-16</sub> as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids

The Sub-picomolar Cu2+ Dissociation Constant of Human Serum Albumin

Thiophosphorylation of free amino acids and enzyme protein by thiophosphoramidate ions

Thymidylate synthase-catalyzed, tetrahydrofolate-dependent self-inactivation by 5-FdUMP

Tyrosine nitration affects thymidylate synthase properties.

Unusual Zn(II) Affinities of Zinc Fingers of Poly(ADP-ribose)Polymerase 1 (PARP-1) Nuclear Protein

cis-Urocanic acid as a potential nickel(II) binding molecule in the human skin