Lista de obras - Sebastian Hoffmann - Dominio Público Uruguay

"ToxRTool", a new tool to assess the reliability of toxicological data

artículo científico publicado en 2009

1.2 Aspects of test assessment

artículo científico publicado en 2009

A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals

artículo científico publicado en 2008

A primer on systematic reviews in toxicology.

artículo científico publicado en 2017

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

artículo científico

Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test

artículo científico publicado en 2018

Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics ⬇️

artículo científico publicado el 10 de febrero de 2012

Categorization of chemicals according to their relative human skin sensitizing potency

artículo científico publicado en 2014

ECVAM prevalidation of three cell transformation assays ⬇️

artículo científico publicado el 1 de enero de 2011

ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study ⬇️

artículo científico publicado el 26 de noviembre de 2011

Effects of BPA in snails

artículo científico publicado en 2006

Estimation of acute oral toxicity using the No Observed Adverse Effect Level (NOAEL) from the 28 day repeated dose toxicity studies in rats

artículo científico publicado en 2008

Evidence-Based Toxicology

artículo científico publicado en 2016

Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity

artículo científico publicado en 2019

Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

artículo científico publicado en 2016

Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations

artículo científico publicado en 2016

Instruments for assessing risk of bias and other methodological criteria of animal studies: omission of well-established methods.

artículo científico publicado en 2014

Integrated Testing Strategies (ITS) for safety assessment.

artículo científico publicado en 2014

Integrated Testing Strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology ⬇️

artículo científico publicado el 1 de enero de 2010

LLNA variability: An essential ingredient for a comprehensive assessment of non-animal skin sensitization test methods and strategies

artículo científico publicado en 2015

Mechanistic validation.

artículo científico publicado en 2013

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database

artículo científico publicado en 2018

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches *.

artículo científico publicado en 2018

Prospective multicentre study of the U-SENS test method for skin sensitization testing

artículo científico publicado en 2015

Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

scientific article published on 28 December 2013

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

artículo científico publicado en 2018

Simple clotting test to detect procoagulant abdominal swabs

artículo científico publicado en 2015

State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.

artículo científico publicado en 2017

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

artículo científico publicado en 2015

The Emergence of Systematic Review in Toxicology

artículo científico publicado en 2016

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds ⬇️

artículo científico

The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity

artículo científico publicado en 2019

Toward Good In Vitro Reporting Standards

artículo científico publicado en 2019

Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility.

artículo científico publicado en 2013

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.

artículo científico publicado en 2018

Validation of the CULTEX® Radial Flow System for the assessment of the acute inhalation toxicity of airborne particles

scientific article published on 16 March 2019

Validation study on the Ocular Irritection assay for eye irritation testing

artículo científico

Lista de obras de Sebastian Hoffmann

"ToxRTool", a new tool to assess the reliability of toxicological data

1.2 Aspects of test assessment

A feasibility study developing an integrated testing strategy assessing skin irritation potential of chemicals

A primer on systematic reviews in toxicology.

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

Adaptation of the Systematic Review Framework to the Assessment of Toxicological Test Methods: Challenges and Lessons Learned with the Zebrafish Embryotoxicity Test

Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics ⬇️

Categorization of chemicals according to their relative human skin sensitizing potency

ECVAM prevalidation of three cell transformation assays ⬇️

ECVAM prevalidation study on in vitro cell transformation assays: General outline and conclusions of the study ⬇️

Effects of BPA in snails

Estimation of acute oral toxicity using the No Observed Adverse Effect Level (NOAEL) from the 28 day repeated dose toxicity studies in rats

Evidence-Based Toxicology

Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity

Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations

Instruments for assessing risk of bias and other methodological criteria of animal studies: omission of well-established methods.

Integrated Testing Strategies (ITS) for safety assessment.

Integrated Testing Strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology ⬇️

LLNA variability: An essential ingredient for a comprehensive assessment of non-animal skin sensitization test methods and strategies

Mechanistic validation.

Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database

Non-animal methods to predict skin sensitization (II): an assessment of defined approaches *.

Prospective multicentre study of the U-SENS test method for skin sensitization testing

Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

Simple clotting test to detect procoagulant abdominal swabs

State-of-the-art and new options to assess T cell activation by skin sensitizers: Cosmetics Europe Workshop.

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

The Emergence of Systematic Review in Toxicology

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds ⬇️

The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity

Toward Good In Vitro Reporting Standards

Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility.

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility.

Validation of the CULTEX® Radial Flow System for the assessment of the acute inhalation toxicity of airborne particles

Validation study on the Ocular Irritection assay for eye irritation testing