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Lista de obras de Robert G. Bristow

"Contextual" synthetic lethality and/or loss of heterozygosity: tumor hypoxia and modification of DNA repair.

artículo científico publicado en 2010

4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer

artículo científico publicado en 2013

A Partner in Crime: Tumor-associated Stroma and Metastatic Prostate Cancer

artículo científico publicado en 2017

A Phase 1 Pilot Study of Preoperative Radiation Therapy for Prostate Cancer: Long-Term Toxicity and Oncologic Outcomes

scientific article published on 06 January 2019

A Prostate Cancer "Nimbosus": Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies

artículo científico publicado en 2017

A Randomized Phase III Study of Neoadjuvant Hormonal Therapy in Patients with Localized Prostate Cancer

artículo científico publicado en 2006

A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study.

artículo científico publicado en 2016

A cinematic magnetic resonance imaging study of milk of magnesia laxative and an antiflatulent diet to reduce intrafraction prostate motion

artículo científico publicado en 2009

A phase I trial of pre-operative radiotherapy for prostate cancer: Clinical and translational studies

artículo científico publicado en 2008

A phase II study of localized prostate cancer treated to 75.6Gy with 3D conformal radiotherapy

artículo científico publicado en 2005

A randomized comparison of interfraction and intrafraction prostate motion with and without abdominal compression

artículo científico publicado en 2008

A randomized trial of supine vs. prone positioning in patients undergoing escalated dose conformal radiotherapy for prostate cancer

article

A role for p53 in the response of bystander cells to receipt of medium borne signals from irradiated cells.

artículo científico publicado en 2011

ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells.

artículo científico publicado en 2011

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer

artículo científico publicado en 2011

Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability

artículo científico publicado en 2005

An arranged marriage for precision medicine: hypoxia and genomic assays in localized prostate cancer radiotherapy

artículo científico

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

artículo científico publicado en 2015

Analysis of variants in DNA damage signalling genes in bladder cancer

artículo científico publicado en 2008

Androgen Withdrawal in Patients Reduces Prostate Cancer Hypoxia: Implications for Disease Progression and Radiation Response

artículo científico publicado en 2007

Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers

artículo científico publicado en 2015

Association between germline HOXB13 G84E mutation and risk of prostate cancer

artículo científico publicado en 2012

BAMQL: a query language for extracting reads from BAM files.

artículo científico publicado en 2016

BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenografts.

artículo científico publicado en 2015

Biodosimetry using radiation-induced micronuclei in skin fibroblasts

artículo científico publicado en 2011

Biomarkers for DNA DSB inhibitors and radiotherapy clinical trials

artículo científico publicado en 2008

Biomarkers of clinical trials using molecular inhibitors and radiotherapy: state-of-the-art. Preface

artículo científico publicado en 2008

Biopsy diagnosis of intraductal carcinoma is prognostic in intermediate and high risk prostate cancer patients treated by radiotherapy.

artículo científico

Cell death in irradiated prostate epithelial cells: role of apoptotic and clonogenic cell kill.

artículo científico publicado en 2003

Changes in apparent diffusion coefficient and T2 relaxation during radiotherapy for prostate cancer.

artículo científico publicado en 2012

Characterization of mutant MUTYH proteins associated with familial colorectal cancer.

artículo científico publicado en 2008

Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability.

artículo científico publicado en 2012

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance

artículo científico publicado en 2008

Clinical Application of High-Dose, Image-Guided Intensity-Modulated Radiotherapy in High-Risk Prostate Cancer

artículo científico publicado en 2009

Clonality of localized and metastatic prostate cancer

artículo científico publicado en 2016

Comment on "Tumor response to radiotherapy regulated by endothelial cell apoptosis" (II)

artículo científico publicado en 2003

Comparing oxygen-sensitive MRI (BOLD R2*) with oxygen electrode measurements: a pilot study in men with prostate cancer.

artículo científico publicado en 2009

Comparison between in vitro radiosensitivity and in vivo radioresponse in murine tumor cell lines. II: In vivo radioresponse following fractionated treatment and in vitro/in vivo correlations.

artículo científico publicado en 1990

Comparison of Pre-processing Methods for Infinium HumanMethylation450 BeadChip Array

artículo científico publicado en 2017

Comprehensive Genomic Profiling Aids in Distinguishing Metastatic Recurrence from Second Primary Cancers.

artículo científico publicado en 2017

Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.

artículo científico publicado en 2010

Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression

artículo científico publicado en 2014

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy

article

Correction to Inherently Multimodal Nanoparticle-Driven Tracking and Real-Time Delineation of Orthotopic Prostate Tumors and Micrometastases.

artículo científico publicado en 2013

Correction: Image guided dose escalated prostate radiotherapy: still room to improve

Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations.

artículo científico publicado en 2018

Curative Radiation Therapy at Time of Progression Under Active Surveillance Compared With Up-front Radical Radiation Therapy for Prostate Cancer.

artículo científico publicado en 2017

Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summa

artículo científico publicado en 2013

Cyclic hypoxia does not alter RAD51 expression or PARP inhibitor cell kill in tumor cells.

artículo científico publicado en 2015

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

artículo científico publicado en 2014

DNA repair targeting and radiotherapy: a focus on the therapeutic ratio

artículo científico publicado en 2010

Defective DNA Strand Break Repair after DNA Damage in Prostate Cancer Cells

article

Deriving patient-specific planning target volume for partial bladder image guided radiation therapy

artículo científico publicado en 2013

Detection of genetic instability at HER-2/neu and p53 loci in breast cancer cells sing Comet-FISH

artículo científico publicado en 2005

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

artículo científico publicado en 2018

Discordance between phosphorylation and recruitment of 53BP1 in response to DNA double-strand breaks.

artículo científico publicado en 2012

Divergent mutational processes distinguish hypoxic and normoxic tumours

artículo científico publicado en 2020

Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells

artículo científico publicado en 2004

Dual Action Enhancement of Gold Nanoparticle Radiosensitization by Pentamidine in Triple Negative Breast Cancer

artículo científico publicado en 2016

Education and Training for Radiation Scientists: Radiation Research Program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12–14, 2003

artículo científico publicado en 2003

Effects of Combined Treatment with Ionizing Radiation and the PARP Inhibitor Olaparib in BRCA Mutant and Wild Type Patient-Derived Pancreatic Cancer Xenografts

artículo científico publicado en 2016

Efficacy of combining GMX1777 with radiation therapy for human head and neck carcinoma

artículo científico publicado en 2010

Electron transfer-based combination therapy of cisplatin with tetramethyl-p-phenylenediamine for ovarian, cervical, and lung cancers.

artículo científico publicado en 2012

Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

scholarly article by Colin S Cooper et al published June 2015 in Nature Genetics

Excellent translational research in oncology: A journey towards novel and more effective anti-cancer therapies

artículo científico publicado en 2016

Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents

artículo científico publicado en 2002

First report on the patient database for the identification of the genetic pathways involved in patients over-reacting to radiotherapy: GENEPI-II.

artículo científico publicado en 2010

From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

artículo científico publicado en 2012

Genome-wide germline correlates of the epigenetic landscape of prostate cancer

artículo científico publicado en 2019

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy

artículo científico publicado en 2019

Genomic hallmarks of localized, non-indolent prostate cancer.

artículo científico publicado en 2017

Genomic, pathological, and clinical heterogeneity as drivers of personalized medicine in prostate cancer

artículo científico

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories.

artículo científico publicado en 2017

Germline MutY human homologue mutations and colorectal cancer: a multisite case-control study

artículo científico publicado en 2008

Germline Mutations in the Kallikrein 6 Region and Predisposition for Aggressive Prostate Cancer

artículo científico publicado en 2017

HDAC inhibitor confers radiosensitivity to prostate stem-like cells

artículo científico publicado en 2013

Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma.

artículo científico publicado en 2018

High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone

article

High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer

artículo científico publicado en 2009

Human tissue Kallikreins: Blood levels and response to radiotherapy in intermediate risk prostate cancer

artículo científico publicado en 2017

Hypoxia Marker GLUT-1 (Glucose Transporter 1) is an Independent Prognostic Factor for Survival in Bladder Cancer Patients Treated with Radical Cystectomy

artículo científico publicado en 2016

Hypoxia and Predicting Radiation Response

artículo científico

Hypoxia and cellular localization influence the radiosensitizing effect of gold nanoparticles (AuNPs) in breast cancer cells.

artículo científico publicado en 2014

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

artículo científico publicado en 2008

Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T

artículo científico publicado en 2011

Hypoxia provokes base excision repair changes and a repair-deficient, mutator phenotype in colorectal cancer cells

artículo científico publicado en 2014

Hypoxia, Androgen Deprivation and Systemic Metastases in Prostate Cancer (In Response to “Antivascular Effects of Neoadjuvant Androgen Deprivation for Prostate Cancer: An In Vivo Human Study Using Susceptibility and Relaxitivity Dynamic MRI”: In

artículo científico publicado en 2012

Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.

artículo científico publicado en 2005

IDH mutation status in prostate cancer.

artículo científico publicado en 2011

IMRT and molecular biological approaches in radiotherapy for prostate cancer

artículo científico publicado en 2009

Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation

artículo científico publicado en 2020

Image guided dose escalated prostate radiotherapy: still room to improve

artículo científico publicado en 2009

Imaging radiation biology for optimised radiation therapy

artículo científico publicado en 2009

Imatinib radiosensitizes bladder cancer by targeting homologous recombination.

artículo científico publicado en 2013

Improved outcomes with dose escalation in localized prostate cancer treated with precision image-guided radiotherapy.

artículo científico publicado en 2017

In Vitro and In Vivo Studies of a New Class of Anticancer Molecules for Targeted Radiotherapy of Cancer.

artículo científico publicado en 2016

In reply to Nieder

artículo científico publicado en 2013

In situ DNA repair assays as guides to personalized breast cancer chemotherapeutics: ready for prime time?

artículo científico publicado en 2011

In vivo studies of the PARP inhibitor, AZD-2281, in combination with fractionated radiotherapy: An exploration of the therapeutic ratio

artículo científico publicado en 2015

Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: a good thing?

artículo científico publicado en 2010

Inherently multimodal nanoparticle-driven tracking and real-time delineation of orthotopic prostate tumors and micrometastases

artículo científico publicado en 2013

Inhibition of breast cancer local relapse by targeting p70S6 kinase activity

artículo científico publicado en 2013

Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer

artículo científico publicado en 2012

Intraductal Carcinoma of the Prostate: Anonymous to Ominous.

artículo científico publicado en 2017

Introduction: DNA Repair and Radiotherapy Targeting: An Overview ⬇️

artículo científico publicado el 1 de octubre de 2010

Inverse Relationship Between Biochemical Outcome and Acute Toxicity After Image-Guided Radiotherapy for Prostate Cancer

article

Investigations of antioxidant-mediated protection and mitigation of radiation-induced DNA damage and lipid peroxidation in murine skin

artículo científico publicado en 2013

Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells: modulation of cellular signals regulating cell cycle and survival

artículo científico publicado en 2012

Late residual gamma-H2AX foci in murine skin are dose responsive and predict radiosensitivity in vivo

artículo científico publicado en 2010

Linking the history of radiation biology to the hallmarks of cancer.

artículo científico

Liver Failure After Abdominal Irradiation: Identifying the Right Suspects.

artículo científico publicado en 2014

Long non-coding RNA urothelial carcinoma associated 1 (UCA1) mediates radiation response in prostate cancer.

artículo científico publicado en 2016

Long-term outcome of radiation-based conservation therapy for invasive bladder cancer.

artículo científico publicado en 2007

Long-term outcomes of a phase II trial of moderate hypofractionated image-guided intensity modulated radiotherapy (IG-IMRT) for localized prostate cancer.

artículo científico publicado en 2016

Longitudinal Cytokine Expression during IMRT for Prostate Cancer and Acute Treatment Toxicity

article

Loss of Brca2 and p53 synergistically promotes genomic instability and deregulation of T-cell apoptosis

artículo científico publicado en 2002

Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells.

artículo científico publicado en 2017

MATE2 Expression Is Associated with Cancer Cell Response to Metformin

artículo científico publicado en 2016

MR-guided prostate biopsy for planning of focal salvage after radiation therapy

artículo científico publicado en 2014

MRE11 expression is predictive of cause-specific survival following radical radiotherapy for muscle-invasive bladder cancer

artículo científico publicado en 2010

MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.

artículo científico publicado en 2011

Male BRCA1 and BRCA2 mutation carriers: a pilot study investigating medical characteristics of patients participating in a prostate cancer prevention clinic

scientific article published on 01 October 2005

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017.

artículo científico publicado en 2017

Mechanistic Insights into Molecular Targeting and Combined Modality Therapy for Aggressive, Localized Prostate Cancer

artículo científico publicado en 2016

Microscopic imaging of DNA repair foci in irradiated normal tissues.

artículo científico publicado en 2009

Mitochondrial mutations drive prostate cancer aggression

artículo científico publicado en 2017

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.

artículo científico publicado en 2016

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

artículo científico publicado en 2018

Molecular landmarks of tumor hypoxia across cancer types

scientific article published on 14 January 2019

Molecular markers predicting radiotherapy response: report and recommendations from an International Atomic Energy Agency technical meeting.

artículo científico publicado en 2005

Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV16-E7 and/or activated H-ras

scientific article published on 01 June 1994

Mutator phenotype in Msh2-deficient murine embryonic fibroblasts ⬇️

artículo científico publicado el 1 de septiembre de 1997

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

artículo científico publicado en 2014

NKX3.1 haploinsufficiency is prognostic for prostate cancer relapse following surgery or image-guided radiotherapy

artículo científico publicado en 2011

NanoStringNormCNV: Pre-processing of NanoString CNV data

artículo científico publicado en 2017

Nanoparticle-Enabled Selective Destruction of Prostate Tumor Using MRI-Guided Focal Photothermal Therapy

artículo científico publicado en 2016

Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model

artículo científico publicado en 2017

Neoadjuvant radiotherapy for locally advanced and high-risk prostate cancer

artículo científico publicado en 2010

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer

scientific article published on 23 January 2020

Not all gleason pattern 4 prostate cancers are created equal: A study of latent prostatic carcinomas in a cystoprostatectomy and autopsy series.

artículo científico publicado en 2015

Novel chemical enhancers of heat shock increase thermal radiosensitization through a mitotic catastrophe pathway

artículo científico publicado en 2007

Nutlin-3 radiosensitizes hypoxic prostate cancer cells independent of p53.

artículo científico publicado en 2008

ONECUT2 is a driver of neuroendocrine prostate cancer

artículo científico publicado en 2019

P53-mediated radioresistance does not correlate with metastatic potential in tumorigenic rat embryo cell lines following oncogene transfection.

artículo científico publicado en 1996

PMH 9907: Long-term outcomes of a randomized phase 3 study of short-term bicalutamide hormone therapy and dose-escalated external-beam radiation therapy for localized prostate cancer

artículo científico publicado en 2016

PRIMA-1(met) radiosensitizes prostate cancer cells independent of their MTp53-status.

artículo científico publicado en 2008

PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy

artículo científico publicado en 2011

Pathological predictors for site of local recurrence after radiotherapy for prostate cancer.

artículo científico publicado en 2012

Patient-specific PTV margins in radiotherapy for bladder cancer – A feasibility study using cone beam CT

artículo científico publicado en 2011

Phase 1B study of amuvatinib in combination with five standard cancer therapies in adults with advanced solid tumors

artículo científico publicado en 2014

Phase 2 trial of guideline-based postoperative image guided intensity modulated radiation therapy for prostate cancer: Toxicity, biochemical, and patient-reported health-related quality-of-life outcomes.

artículo científico publicado en 2015

Phase II Trial of Hypofractionated Image-Guided Intensity-Modulated Radiotherapy for Localized Prostate Adenocarcinoma

article

Plasma osteopontin as a biomarker of prostate cancer aggression: relationship to risk category and treatment response.

artículo científico publicado en 2012

Polarographic electrode study of tumor oxygenation in clinically localized prostate cancer.

artículo científico publicado en 2004

Poly(ADP-ribose) polymerase inhibition as a model for synthetic lethality in developing radiation oncology targets.

artículo científico publicado en 2010

Post-operative radiotherapy for recurrent dermoid cysts of the spine: a report of 3 cases

artículo científico publicado en 1997

Practical approaches to proteomic biomarkers within prostate cancer radiotherapy trials

artículo científico publicado en 2008

Pre-radiotherapy identification of individual genomic profile to avoid, by resort to customized radiosensitizers, the risk of radioresistance development in patients with localized prostate cancer: author reply

artículo científico publicado en 2015

Primary esophageal and gastro-esophageal junction cancer xenograft models: clinicopathological features and engraftment

artículo científico publicado en 2013

Prognostic utility of cell cycle progession score in men with prostate cancer after primary external beam radiation therapy. In regard to Freedland et al.

artículo científico publicado en 2014

Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.

artículo científico publicado en 2006

Propensity Score Analysis of Radical Cystectomy Versus Bladder-Sparing Trimodal Therapy in the Setting of a Multidisciplinary Bladder Cancer Clinic

artículo científico publicado en 2017

Prostate cancer screening characteristics in men with BRCA1/2 mutations attending a high-risk prevention clinic

artículo científico publicado en 2014

Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression.

artículo científico publicado en 2015

Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma

artículo científico publicado en 2012

Protein-protein interactions occur between p53 phosphoforms and ATM and 53BP1 at sites of exogenous DNA damage.

artículo científico publicado en 2011

RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation

artículo científico publicado en 2016

RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage.

artículo científico publicado en 2014

Radiation Resistance in Cancer Therapy: meeting summary and research opportunities. Report of an NCI Workshop held September 1-3, 2010

artículo científico publicado en 2011

Radiation Therapy Oncology Group translational research program stem cell symposium: incorporating stem cell hypotheses into clinical trials

artículo científico publicado en 2009

Radiation and new molecular agents part I: targeting ATM-ATR checkpoints, DNA repair, and the proteasome

artículo científico publicado en 2006

Radiosensitivity of cancer-initiating cells and normal stem cells (or what the Heisenberg uncertainly principle has to do with biology)

scientific article published on April 2009

Radiosensitization by gold nanoparticles: Will they ever make it to the clinic?

artículo científico publicado en 2017

Radiotherapy and Marfan syndrome: a report of two cases

artículo científico publicado en 2005

Radiotherapy-induced miR-223 prevents relapse of breast cancer by targeting the EGF pathway.

artículo científico publicado en 2016

Re: Vikram, B., The PSA conundrum. Radiother Oncol, 2004. 71(1): p. 1–2

artículo científico publicado en 2004

Report from the SWOG Radiation Oncology Committee: Research Objectives Workshop 2017

artículo científico publicado en 2018

Reprogramming metabolism with metformin improves tumor oxygenation and radiotherapy response

artículo científico publicado en 2013

Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF ras-transformants-expressing gain of function MTp53

scientific article published on 01 May 2003

Resistance to bleomycin in cancer cell lines is characterized by prolonged doubling time, reduced DNA damage and evasion of G2/M arrest and apoptosis

artículo científico publicado en 2013

Response

Response to “Intraoperative Radiotherapy During Radical Prostatectomy for Locally Advanced Prostate Cancer: Technical and Dosimetric Aspects” (Int J Radiat Oncol Biol Phys 2009; in press)

artículo científico publicado en 2010

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer

artículo científico publicado en 2010

Role of Autophagy as a Survival Mechanism for Hypoxic Cells in Tumors

artículo científico publicado en 2016

Role of Principal Component Analysis in Predicting Toxicity in Prostate Cancer Patients Treated With Hypofractionated Intensity-Modulated Radiation Therapy

article

SeqControl: process control for DNA sequencing

artículo científico publicado en 2014

Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.

artículo científico publicado en 2018

ShatterProof: operational detection and quantification of chromothripsis

artículo científico publicado en 2014

Significant Radiation Enhancement Effects by Gold Nanoparticles in Combination with Cisplatin in Triple Negative Breast Cancer Cells and Tumor Xenografts.

artículo científico publicado en 2017

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

artículo científico publicado en 2021

Spatial genomic heterogeneity within localized, multifocal prostate cancer

artículo científico publicado en 2015

Synergistic action of image-guided radiotherapy and androgen deprivation therapy

artículo científico

Synergistic nanoparticulate drug combination overcomes multidrug resistance, increases efficacy, and reduces cardiotoxicity in a nonimmunocompromised breast tumor model.

artículo científico publicado en 2014

T1/T2 glottic cancer managed by external beam radiotherapy: the influence of pretreatment hemoglobin on local control

artículo científico publicado en 1998

TMPRSS2-ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer.

artículo científico

TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair

artículo científico publicado en 2013

TP53 and Prognosis in mCRPC Survival: Biology or Coincidence?

scientific article published on 04 January 2019

Targeting DNA repair for precision radiotherapy: Balancing the therapeutic ratio.

artículo científico publicado en 2017

Targeting homologous recombination using imatinib results in enhanced tumor cell chemosensitivity and radiosensitivity

artículo científico publicado en 2009

Testosterone in Androgen Receptor Signaling and DNA Repair: Enemy or Frenemy?

artículo científico publicado en 2016

The Evolving Narrative of DNA Repair Gene Defects: Distinguishing Indolent from Lethal Prostate Cancer.

artículo científico publicado en 2017

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

artículo científico publicado en 2010

The Terry Fox Research Institute Canadian Prostate Cancer Biomarker Network: an analysis of a pan-Canadian multi-center cohort for biomarker validation

article

The Utility of Serum CA9 for Prognostication in Prostate Cancer

artículo científico publicado en 2016

The effect of bowel preparation regime on interfraction rectal filling variation during image guided radiotherapy for prostate cancer

artículo científico publicado en 2017

The influence of BRCA2 mutation on localized prostate cancer

artículo científico publicado en 2019

The initiation of a multidisciplinary bladder cancer clinic and the uptake of neoadjuvant chemotherapy: A time-series analysis.

artículo científico publicado en 2016

The p53 protein family and radiation sensitivity: Yes or no?

artículo científico publicado en 2004

The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras.

artículo científico publicado en 1995

The receptor tyrosine kinase inhibitor amuvatinib (MP470) sensitizes tumor cells to radio- and chemo-therapies in part by inhibiting homologous recombination

artículo científico publicado en 2011

The therapeutic ratio is preserved for radiotherapy or cisplatin treatment in BRCA2-mutated prostate cancers

artículo científico publicado en 2011

Thyroid dose distribution in dental radiography

artículo científico publicado en 1989

Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors

artículo científico publicado en 2016

Treatment of radiation proctitis with hyperbaric oxygen

artículo científico publicado en 2005

Tumor Hypoxia Predicts Biochemical Failure following Radiotherapy for Clinically Localized Prostate Cancer

artículo científico publicado en 2012

Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair.

artículo científico publicado en 2010

Tumor hypoxia as a driving force in genetic instability.

artículo científico

Tumor hypoxia as a modifier of DNA strand break and cross-link repair.

artículo científico publicado en 2009

Tumor senescence and radioresistant tumor-initiating cells (TICs): let sleeping dogs lie!

artículo científico publicado en 2010

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

artículo científico publicado en 2014

Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity.

artículo científico publicado en 2017

Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer

artículo científico publicado en 2011

Use of Sequenom sample ID Plus® SNP genotyping in identification of FFPE tumor samples

artículo científico publicado en 2014

Valection: design optimization for validation and verification studies

scholarly article by Christopher I Cooper published in September 2018

WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma

artículo científico publicado en 2014

WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells.

artículo científico publicado en 2008

miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1.

artículo científico publicado en 2013

p53 protein expression or protein function?

scientific article published on 01 July 1996

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