Lista de obras - Brian L Black - Dominio Público Uruguay

A p38 MAPK-MEF2C pathway regulates B-cell proliferation

scientific journal article

A single mutation causes a spectrum of cardiovascular defects: the potential role of genetic modifiers, epigenetic influences, and stochastic events in phenotypic variability

artículo científico publicado en 2005

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation

artículo científico publicado en 2007

An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.

artículo científico

An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo.

artículo científico publicado en 2009

BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development

scientific journal article

Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism

scientific journal article

Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage

scientific article published on 03 December 2018

ChIP-Seq identification of weakly conserved heart enhancers

artículo científico publicado en 2010

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

artículo científico publicado en 2013

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

artículo científico publicado en 2008

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

artículo científico publicado en 2021

Control of ribosomal protein synthesis by the Microprocessor complex

artículo científico publicado en 2021

Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites

artículo científico publicado en 2017

Determinants of myogenic specificity within MyoD are required for noncanonical E box binding

artículo científico publicado en 2007

Development of the endocardium

artículo científico publicado en 2010

Developmental biology: Diversity in the lymphatic vasculature

artículo científico publicado en 2015

Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer

artículo científico publicado en 2010

Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

artículo científico publicado en 2015

FGF-dependent regulation of VEGF receptor 2 expression in mice ⬇️

artículo científico publicado el 1 de julio de 2011

GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

artículo científico publicado en 2008

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

scientific journal article

HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo

artículo científico publicado en 2004

Hand2 function in second heart field progenitors is essential for cardiogenesis.

artículo científico publicado en 2010

Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).

artículo científico publicado en 2008

Identification of novel Fgf enhancers and their role in dental evolution

artículo científico publicado en 2016

Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.

artículo científico publicado en 2009

Large-scale discovery of enhancers from human heart tissue

artículo científico publicado en 2011

MEF2B is a potent transactivator expressed in early myogenic lineages

scientific journal article

Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins

artículo científico publicado en 2009

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

artículo científico publicado en 2004

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells

artículo científico publicado en 2015

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor

scientific journal article

Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2

artículo científico publicado en 1998

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

scientific journal article

Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice.

artículo científico publicado en 2015

N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor

scientific journal article

NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity

artículo científico publicado en 2014

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

artículo científico publicado en 2017

Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium

scientific journal article

Regulation of endothelial and hematopoietic development by the ETS transcription factor Etv2.

artículo científico publicado en 2012

Reptilian heart development and the molecular basis of cardiac chamber evolution

scientific journal article

Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling

scientific journal article

Specification of the mouse cardiac conduction system in the absence of Endothelin signaling

artículo científico publicado en 2014

TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

artículo científico publicado en 2001

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

artículo científico publicado en 2005

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

artículo científico publicado en 2011

The heart's Da Vinci code: a Renaissance at Keystone

artículo científico publicado en 2007

The mouse MRF4 promoter is trans-activated directly and indirectly by muscle-specific transcription factors.

artículo científico publicado en 1995

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

artículo científico publicado en 1998

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

artículo científico publicado en 2005

The transcription factor MEF2C is required for craniofacial development

artículo científico publicado en 2007

Transcription factor pathways and congenital heart disease.

artículo científico

Transcription factor protein interactomes reveal genetic determinants in heart disease

artículo científico publicado en 2022

Transcriptional control of endothelial cell development.

artículo científico publicado en 2009

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

artículo científico publicado en 1998

Transgenic mice that express Cre recombinase under control of a skeletal muscle-specific promoter from mef2c

artículo científico publicado en 2005

Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin

scientific article published on 08 February 2019

Vesicular stomatitis virus matrix protein inhibits host cell-directed transcription of target genes in vivo ⬇️

artículo científico publicado el 1 de julio de 1992

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo

artículo científico publicado en 2003

Lista de obras de Brian L Black

A p38 MAPK-MEF2C pathway regulates B-cell proliferation

A single mutation causes a spectrum of cardiovascular defects: the potential role of genetic modifiers, epigenetic influences, and stochastic events in phenotypic variability

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation

An arterial-specific enhancer of the human endothelin converting enzyme 1 (ECE1) gene is synergistically activated by Sox17, FoxC2, and Etv2.

An endoderm-specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein-binding sites for function in vivo.

BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development

Bmp signaling regulates myocardial differentiation from cardiac progenitors through a MicroRNA-mediated mechanism

Cardiovascular development and survival require Mef2c function in the myocardial but not the endothelial lineage

ChIP-Seq identification of weakly conserved heart enhancers

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors

Comprehensive cell type decomposition of circulating cell-free DNA with CelFiE

Control of ribosomal protein synthesis by the Microprocessor complex

Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites

Determinants of myogenic specificity within MyoD are required for noncanonical E box binding

Development of the endocardium

Developmental biology: Diversity in the lymphatic vasculature

Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer

Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

FGF-dependent regulation of VEGF receptor 2 expression in mice ⬇️

GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element

HRC is a direct transcriptional target of MEF2 during cardiac, skeletal, and arterial smooth muscle development in vivo

Hand2 function in second heart field progenitors is essential for cardiogenesis.

Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2).

Identification of novel Fgf enhancers and their role in dental evolution

Isl1 is a direct transcriptional target of Forkhead transcription factors in second-heart-field-derived mesoderm.

Large-scale discovery of enhancers from human heart tissue

MEF2B is a potent transactivator expressed in early myogenic lineages

Maintenance of blastemal proliferation by functionally diverse epidermis in regenerating zebrafish fins

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor

Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2

Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation

Myocyte enhancer factor 2C function in skeletal muscle is required for normal growth and glucose metabolism in mice.

N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor

NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium

Regulation of endothelial and hematopoietic development by the ETS transcription factor Etv2.

Reptilian heart development and the molecular basis of cardiac chamber evolution

Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling

Specification of the mouse cardiac conduction system in the absence of Endothelin signaling

TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of SOX10

The heart's Da Vinci code: a Renaissance at Keystone

The mouse MRF4 promoter is trans-activated directly and indirectly by muscle-specific transcription factors.

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

The right ventricle, outflow tract, and ventricular septum comprise a restricted expression domain within the secondary/anterior heart field

The transcription factor MEF2C is required for craniofacial development

Transcription factor pathways and congenital heart disease.

Transcription factor protein interactomes reveal genetic determinants in heart disease

Transcriptional control of endothelial cell development.

Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

Transgenic mice that express Cre recombinase under control of a skeletal muscle-specific promoter from mef2c

Venous endothelin modulates responsiveness of cardiac sympathetic axons to arterial semaphorin

Vesicular stomatitis virus matrix protein inhibits host cell-directed transcription of target genes in vivo ⬇️

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo