Lista de obras - Bruno Antonny - Dominio Público Uruguay

A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalF

artículo científico publicado en 2013

A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

artículo científico publicado en 2016

A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP

artículo científico publicado en 2013

A general amphipathic alpha-helical motif for sensing membrane curvature.

artículo científico publicado en 2007

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets.

artículo científico publicado en 2018

A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.

artículo científico publicado en 1998

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

artículo científico publicado en 1996

A novel magnesium-dependent mechanism for the activation of transducin by fluoride

artículo científico publicado en 1990

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

scientific article published in Nature Communications

A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity.

artículo científico publicado en 2004

A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment

artículo científico publicado en 2014

Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols

artículo científico publicado en 1997

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage.

artículo científico publicado en 2018

Amphipathic helices and membrane curvature

artículo científico publicado en 2009

Amphipathic lipid packing sensor motifs: probing bilayer defects with hydrophobic residues

artículo científico publicado en 2013

Arf GTPase regulation through cascade mechanisms and positive feedback loops

artículo científico publicado en 2013

Arf1 and membrane curvature cooperate to recruit Arfaptin2 to liposomes.

artículo científico publicado en 2013

ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions.

artículo científico publicado en 2009

ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif.

artículo científico publicado en 2005

Asymmetric tethering of flat and curved lipid membranes by a golgin.

artículo científico publicado en 2008

Binding site of brefeldin A at the interface between the small G protein ADP-ribosylation factor 1 (ARF1) and the nucleotide-exchange factor Sec7 domain

artículo científico publicado en 2000

Biophysical and pharmacological properties of large conductance Ca(2+)-activated K+ channels in N1E-115 cells

scientific article published on 01 November 1994

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

artículo científico publicado en 1999

Building lipid 'PIPelines' throughout the cell by ORP/Osh proteins

artículo científico publicado en 2014

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

artículo científico publicado en 2013

COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension

artículo científico publicado en 2008

Cargo selection into COPII vesicles is driven by the Sec24p subunit

artículo científico publicado en 2002

Cell biology. Vitamin currency in a lipid exchange market

artículo científico publicado en 2013

Cell biology: Detached membrane bending

artículo científico publicado en 2009

Cell biology: helices sculpt membrane

artículo científico publicado en 2005

Characterization of the aluminum and beryllium fluoride species which activate transducin. Analysis of the binding and dissociation kinetics

artículo científico publicado en 1992

Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature

artículo científico publicado en 2013

Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity.

artículo científico publicado en 2012

Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat

artículo científico publicado en 2008

Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam

artículo científico publicado en 2002

Dual interaction of ADP ribosylation factor 1 with Sec7 domain and with lipid membranes during catalysis of guanine nucleotide exchange

artículo científico publicado en 1999

Dynamics of the COPII coat with GTP and stable analogues

artículo científico publicado en 2001

ER export: public transportation by the COPII coach

artículo científico publicado en 2001

From zero to six double bonds: phospholipid unsaturation and organelle function.

artículo científico

GEF and glucosylation assays on liposome-bound Rac.

artículo científico publicado en 2006

GTP hydrolysis by purified alpha-subunit of transducin and its complex with the cyclic GMP phosphodiesterase inhibitor

artículo científico publicado en 1993

GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants

artículo científico publicado en 1991

GTP-dependent binding of Gi, G(o) and Gs to the gamma-subunit of the effector of Gt

artículo científico publicado en 1994

HELIQUEST: a web server to screen sequences with specific alpha-helical properties.

artículo científico publicado en 2008

Homeoviscous Adaptation and the Regulation of Membrane Lipids

artículo científico publicado en 2016

In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors

artículo científico publicado en 2008

Insights into the mechanisms of sterol transport between organelles

artículo científico publicado en 2013

Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies

artículo científico publicado en 1993

Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids, and influence of the membrane environment

artículo científico publicado en 2014

Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop

artículo científico publicado en 2010

Lipid cell biology. Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins.

artículo científico publicado en 2014

Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature

artículo científico publicado en 2003

Lipid unsaturation and organelle dynamics.

artículo científico publicado en 2016

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

artículo científico publicado en 2014

Liposomes in the study of GDP/GTP cycle of Arf and related small G proteins

artículo científico publicado en 2003

Mechanisms of membrane curvature sensing

artículo científico publicado en 2011

Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone

artículo científico publicado en 2015

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.

artículo científico publicado en 2015

Membrane bending: the power of protein imbalance.

artículo científico publicado en 2013

Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation

artículo científico publicado en 2005

Membrane deformation by protein coats

artículo científico publicado en 2006

Membrane fission by dynamin: what we know and what we need to know

artículo científico publicado en 2016

Modulation of the GTPase activity of transducin. Kinetic studies of reconstituted systems

scientific article published on 01 December 1994

Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor

artículo científico publicado en 2020

N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange

scientific article published on 01 April 1997

Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites

artículo científico publicado en 2021

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

artículo científico publicado en 2011

PIP2: activator ... or terminator of small G proteins?

scientific article published on 01 March 1998

Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

artículo científico publicado en 1996

Real-time assays for the assembly-disassembly cycle of COP coats on liposomes of defined size

artículo científico publicado en 2005

Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno

artículo científico publicado en 1997

SNARE filtering by dynamin

artículo científico publicado en 2004

Self-assembly of minimal COPII cages

artículo científico publicado en 2003

Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP.

artículo científico publicado en 2017

Structure of the Sec7 domain of the Arf exchange factor ARNO

artículo científico publicado en 1998

Targeting surface voids to counter membrane disorders in lipointoxication-related diseases.

artículo científico publicado en 2016

The G protein cascade of visual transduction: kinetics and regulation.

artículo científico publicado en 1993

The Long and Short of Membrane Fission

The Many Faces of Amphipathic Helices.

artículo científico publicado en 2018

The apparent cooperativity of some GPCRs does not necessarily imply dimerization.

scientific article published on 05 March 2009

The counterflow transport of sterols and PI4P.

artículo científico publicado en 2016

The mechanism of aluminum-independent G-protein activation by fluoride and magnesium. 31P NMR spectroscopy and fluorescence kinetic studies.

artículo científico publicado en 1993

The transbilayer distribution of polyunsaturated phospholipids determines their facilitating effect on membrane deformation

scientific article published on 01 February 2020

Two lipid-packing sensor motifs contribute to the sensitivity of ArfGAP1 to membrane curvature.

artículo científico publicado en 2007

[Regulation of vesicular transport by membrane curvature]

scientific article published on 01 May 2009

α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding.

artículo científico publicado en 2011

Lista de obras de Bruno Antonny

A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalF

A filter at the entrance of the Golgi that selects vesicles according to size and bulk lipid composition

A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP

A general amphipathic alpha-helical motif for sensing membrane curvature.

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets.

A glutamic finger in the guanine nucleotide exchange factor ARNO displaces Mg2+ and the beta-phosphate to destabilize GDP on ARF1.

A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains

A novel magnesium-dependent mechanism for the activation of transducin by fluoride

A phosphatidylinositol-4-phosphate powered exchange mechanism to create a lipid gradient between membranes

A phosphatidylserine-binding site in the cytosolic fragment of Clostridium sordellii lethal toxin facilitates glucosylation of membrane-bound Rac and is required for cytotoxicity.

A sub-nanometre view of how membrane curvature and composition modulate lipid packing and protein recruitment

Activation of ADP-ribosylation factor 1 GTPase-activating protein by phosphatidylcholine-derived diacylglycerols

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage.

Amphipathic helices and membrane curvature

Amphipathic lipid packing sensor motifs: probing bilayer defects with hydrophobic residues

Arf GTPase regulation through cascade mechanisms and positive feedback loops

Arf1 and membrane curvature cooperate to recruit Arfaptin2 to liposomes.

ArfGAP1 generates an Arf1 gradient on continuous lipid membranes displaying flat and curved regions.

ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif.

Asymmetric tethering of flat and curved lipid membranes by a golgin.

Binding site of brefeldin A at the interface between the small G protein ADP-ribosylation factor 1 (ARF1) and the nucleotide-exchange factor Sec7 domain

Biophysical and pharmacological properties of large conductance Ca(2+)-activated K+ channels in N1E-115 cells

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

Building lipid 'PIPelines' throughout the cell by ORP/Osh proteins

COPI buds 60-nm lipid droplets from reconstituted water-phospholipid-triacylglyceride interfaces, suggesting a tension clamp function

COPI coat assembly occurs on liquid-disordered domains and the associated membrane deformations are limited by membrane tension

Cargo selection into COPII vesicles is driven by the Sec24p subunit

Cell biology. Vitamin currency in a lipid exchange market

Cell biology: Detached membrane bending

Cell biology: helices sculpt membrane

Characterization of the aluminum and beryllium fluoride species which activate transducin. Analysis of the binding and dissociation kinetics

Conical lipids in flat bilayers induce packing defects similar to that induced by positive curvature

Curvature, lipid packing, and electrostatics of membrane organelles: defining cellular territories in determining specificity.

Discrete determinants in ArfGAP2/3 conferring Golgi localization and regulation by the COPI coat

Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam

Dual interaction of ADP ribosylation factor 1 with Sec7 domain and with lipid membranes during catalysis of guanine nucleotide exchange

Dynamics of the COPII coat with GTP and stable analogues

ER export: public transportation by the COPII coach

From zero to six double bonds: phospholipid unsaturation and organelle function.

GEF and glucosylation assays on liposome-bound Rac.

GTP hydrolysis by purified alpha-subunit of transducin and its complex with the cyclic GMP phosphodiesterase inhibitor

GTP hydrolysis mechanisms in ras p21 and in the ras-GAP complex studied by fluorescence measurements on tryptophan mutants

GTP-dependent binding of Gi, G(o) and Gs to the gamma-subunit of the effector of Gt

HELIQUEST: a web server to screen sequences with specific alpha-helical properties.

Homeoviscous Adaptation and the Regulation of Membrane Lipids

In vitro assays to characterize inhibitors of the activation of small G proteins by their guanine nucleotide exchange factors

Insights into the mechanisms of sterol transport between organelles

Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies

Interaction of the Spo20 membrane-sensor motif with phosphatidic acid and other anionic lipids, and influence of the membrane environment

Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop

Lipid cell biology. Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins.

Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature

Lipid unsaturation and organelle dynamics.

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

Liposomes in the study of GDP/GTP cycle of Arf and related small G proteins

Mechanisms of membrane curvature sensing

Membrane Curvature Sensing by Amphipathic Helices Is Modulated by the Surrounding Protein Backbone

Membrane Protein Structure, Function, and Dynamics: a Perspective from Experiments and Theory.

Membrane bending: the power of protein imbalance.

Membrane curvature and the control of GTP hydrolysis in Arf1 during COPI vesicle formation

Membrane deformation by protein coats

Membrane fission by dynamin: what we know and what we need to know

Modulation of the GTPase activity of transducin. Kinetic studies of reconstituted systems

Molecular and cellular dissection of the oxysterol-binding protein cycle through a fluorescent inhibitor

N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange

Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

PIP2: activator ... or terminator of small G proteins?

Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

Real-time assays for the assembly-disassembly cycle of COP coats on liposomes of defined size

Role of protein-phospholipid interactions in the activation of ARF1 by the guanine nucleotide exchange factor Arno

SNARE filtering by dynamin

Self-assembly of minimal COPII cages

Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP.

Structure of the Sec7 domain of the Arf exchange factor ARNO

Targeting surface voids to counter membrane disorders in lipointoxication-related diseases.

The G protein cascade of visual transduction: kinetics and regulation.

The Long and Short of Membrane Fission

The Many Faces of Amphipathic Helices.