Lista de obras - Damjana Rozman - Dominio Público Uruguay

A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).

artículo científico publicado en 2002

A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols.

artículo científico publicado en 2003

Acrolein consumption induces systemic dyslipidemia and lipoprotein modification

artículo científico publicado en 2010

Acrolein-induced dyslipidemia and acute-phase response are independent of HMG-CoA reductase.

artículo científico publicado en 2011

Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis

artículo científico publicado en 2010

Altered expression of the steroid bioconverting pathway in pAN 7-1 transformants of Cochliobolus lunatus

artículo científico publicado en 1991

Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2.

artículo científico publicado en 2013

An algorithm for rapid computational construction of metabolic networks: a cholesterol biosynthesis example

artículo científico publicado en 2013

CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver

artículo científico publicado en 2008

CYP53A15 of Cochliobolus lunatus, a target for natural antifungal compounds.

artículo científico publicado en 2008

Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents

artículo científico publicado en 1999

Cholesterogenic genes expression in brain and liver of ganglioside-deficient mice.

artículo científico publicado en 2012

Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters ⬇️

artículo científico publicado el 24 de febrero de 2012

Circadian events in human diseases and in cytochrome P450-related drug metabolism and therapy.

artículo científico publicado en 2013

Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland--involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1.

artículo científico publicado en 2011

Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice.

artículo científico publicado en 2011

Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?

artículo científico publicado en 2005

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells.

artículo científico publicado en 2009

Crosstalk between cholesterol homeostasis and drug metabolism

artículo científico publicado en 2008

Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist.

artículo científico publicado en 2012

Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14alpha-demethylase (CYP51) in spermatids

artículo científico publicado en 1999

Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.

artículo científico publicado en 2011

Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor

artículo científico publicado en 2007

Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor

artículo científico publicado en 2013

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling

artículo científico publicado en 2017

Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent

artículo científico publicado en 2008

Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

artículo científico publicado en 2009

Elevated expression of lanosterol 14alpha-demethylase (CYP51) and the synthesis of oocyte meiosis-activating sterols in postmeiotic germ cells of male rats

artículo científico publicado en 1998

Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form.

artículo científico publicado en 2008

Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome

artículo científico publicado en 2006

From Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma: A Systems Understanding

artículo científico publicado en 2014

Functional genomics approaches to studies of the cytochrome p450 superfamily.

artículo científico publicado en 2007

Genomic aspects of NAFLD pathogenesis.

artículo científico

Heterologous transformation of Cochliobolus lunatus

artículo científico publicado en 1991

Inducible cAMP Early Repressor Regulates the Period 1 Gene of the Hepatic and Adrenal Clocks ⬇️

artículo científico publicado el 25 de febrero de 2013

Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis.

artículo científico publicado en 2010

Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.

artículo científico publicado en 2009

Investigation of the CYP2C9 induction profile in human hepatocytes by combining experimental and modelling approaches.

artículo científico publicado en 2009

Isolation of genomic DNA from filamentous fungi with high glucan level

scientific article published on 01 March 1994

Lanosterol 14alpha-demethylase (CYP51) and spermatogenesis

artículo científico publicado en 1998

Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol

artículo científico publicado en 2000

Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis

artículo científico publicado en 2002

Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation

artículo científico publicado en 2003

Large-scale computational models of liver metabolism: How far from the clinics?

artículo científico publicado en 2017

Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways

artículo científico publicado en 2013

Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51) ⬇️

artículo científico publicado el 18 de marzo de 2013

Mammalian cytochromes P450--importance of tissue specificity.

artículo científico publicado en 2006

Molecular Interactions between NAFLD and Xenobiotic Metabolism.

artículo científico publicado en 2013

Molecular cloning and partial characterisation of the mouse Cyp51 cDNA

scientific article published on 01 January 2000

Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome

artículo científico publicado en 2011

New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer

artículo científico publicado en 2004

New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8.

artículo científico publicado en 2001

Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation

artículo científico publicado en 2011

Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).

artículo científico publicado en 2007

Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis

artículo científico publicado en 2012

Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle

artículo científico publicado en 2011

Polymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure.

artículo científico publicado en 2013

Pre-cholesterol precursors in gametogenesis

artículo científico publicado en 2005

Progesterone metabolism by the filamentous fungus Cochliobolus lunatus

artículo científico publicado en 1994

Regulation of hepatic cytochromes p450 by lipids and cholesterol.

artículo científico publicado en 2011

Sex differences in the hepatic cholesterol sensing mechanisms in mice.

artículo científico publicado en 2013

Steroidal triterpenes of cholesterol synthesis.

artículo científico publicado en 2013

Sterols in spermatogenesis and sperm maturation.

artículo científico publicado en 2012

Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes

artículo científico publicado en 1996

TNF-alpha interferes with lipid homeostasis and activates acute and proatherogenic processes

artículo científico publicado en 2007

The Interplay between Circadian System, Cholesterol Synthesis, and Steroidogenesis Affects Various Aspects of Female Reproduction

artículo científico publicado en 2013

The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism.

artículo científico publicado en 2008

The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action

artículo científico publicado en 2011

The impact of a new emotional self-management program on stress, emotions, heart rate variability, DHEA and cortisol

artículo científico publicado en 1998

The interplay of cis-regulatory elements rules circadian rhythms in mouse liver

artículo científico publicado en 2012

The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

artículo científico publicado en 1996

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

artículo científico publicado en 1996

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

artículo científico publicado en 2019

Timing of circadian genes in mammalian tissues.

artículo científico publicado en 2014

Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.

artículo científico publicado en 2009

Transformation of Cochliobolus lunatus with pUT 720 changes the steroid hydroxylating ability of the fungus

artículo científico publicado en 1992

Lista de obras de Damjana Rozman

A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).

A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols.

Acrolein consumption induces systemic dyslipidemia and lipoprotein modification

Acrolein-induced dyslipidemia and acute-phase response are independent of HMG-CoA reductase.

Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis

Altered expression of the steroid bioconverting pathway in pAN 7-1 transformants of Cochliobolus lunatus

Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2.

An algorithm for rapid computational construction of metabolic networks: a cholesterol biosynthesis example

CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver

CYP53A15 of Cochliobolus lunatus, a target for natural antifungal compounds.

Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents

Cholesterogenic genes expression in brain and liver of ganglioside-deficient mice.

Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters ⬇️

Circadian events in human diseases and in cytochrome P450-related drug metabolism and therapy.

Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland--involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1.

Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice.

Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?

Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells.

Crosstalk between cholesterol homeostasis and drug metabolism

Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist.

Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14alpha-demethylase (CYP51) in spermatids

Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.

Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor

Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor

Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling

Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent

Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers

Elevated expression of lanosterol 14alpha-demethylase (CYP51) and the synthesis of oocyte meiosis-activating sterols in postmeiotic germ cells of male rats

Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form.

Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome

From Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma: A Systems Understanding

Functional genomics approaches to studies of the cytochrome p450 superfamily.

Genomic aspects of NAFLD pathogenesis.

Heterologous transformation of Cochliobolus lunatus

Inducible cAMP Early Repressor Regulates the Period 1 Gene of the Hepatic and Adrenal Clocks ⬇️

Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis.

Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.

Investigation of the CYP2C9 induction profile in human hepatocytes by combining experimental and modelling approaches.

Isolation of genomic DNA from filamentous fungi with high glucan level

Lanosterol 14alpha-demethylase (CYP51) and spermatogenesis

Lanosterol 14alpha-demethylase (CYP51), NADPH-cytochrome P450 reductase and squalene synthase in spermatogenesis: late spermatids of the rat express proteins needed to synthesize follicular fluid meiosis activating sterol

Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis

Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation

Large-scale computational models of liver metabolism: How far from the clinics?

Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways

Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51) ⬇️

Mammalian cytochromes P450--importance of tissue specificity.

Molecular Interactions between NAFLD and Xenobiotic Metabolism.

Molecular cloning and partial characterisation of the mouse Cyp51 cDNA

Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome

New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer

New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8.

Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation

Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).

Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis

Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle

Polymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure.

Pre-cholesterol precursors in gametogenesis

Progesterone metabolism by the filamentous fungus Cochliobolus lunatus

Regulation of hepatic cytochromes p450 by lipids and cholesterol.

Sex differences in the hepatic cholesterol sensing mechanisms in mice.

Steroidal triterpenes of cholesterol synthesis.

Sterols in spermatogenesis and sperm maturation.

Structure and mapping of the human lanosterol 14alpha-demethylase gene (CYP51) encoding the cytochrome P450 involved in cholesterol biosynthesis; comparison of exon/intron organization with other mammalian and fungal CYP genes

TNF-alpha interferes with lipid homeostasis and activates acute and proatherogenic processes

The Interplay between Circadian System, Cholesterol Synthesis, and Steroidogenesis Affects Various Aspects of Female Reproduction

The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism.

The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action

The impact of a new emotional self-management program on stress, emotions, heart rate variability, DHEA and cortisol

The interplay of cis-regulatory elements rules circadian rhythms in mouse liver

The three human cytochrome P450 lanosterol 14 alpha-demethylase (CYP51) genes reside on chromosomes 3, 7, and 13: structure of the two retrotransposed pseudogenes, association with a line-1 element, and evolution of the human CYP51 family

The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

Timing of circadian genes in mammalian tissues.

Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.

Transformation of Cochliobolus lunatus with pUT 720 changes the steroid hydroxylating ability of the fungus