Lista de obras - Philippe Pasero - Dominio Público Uruguay

A 'DNA replication' signature of progression and negative outcome in colorectal cancer

artículo científico publicado en 2009

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy

artículo científico publicado en 2014

A journey into the nucleus. Conference on Nuclear Structure and Dynamics

artículo científico publicado en 2008

A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

artículo científico publicado en 1999

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

artículo científico publicado en 2002

An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes

artículo científico publicado en 2006

Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing.

artículo científico publicado en 2012

Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response

artículo científico publicado en 2010

Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses

artículo científico publicado en 2007

Caught in the Act: R-Loops Are Cleaved by Structure-Specific Endonucleases to Generate DSBs

Closing the MCM cycle at replication termination sites

artículo científico publicado en 2014

Cohesin association to replication sites depends on rad50 and promotes fork restart

artículo científico publicado en 2012

Common DNA structural features exhibited by eukaryotic ribosomal gene promoters.

artículo científico publicado en 1996

Cyclin B-cdk1 kinase stimulates ORC- and Cdc6-independent steps of semiconservative plasmid replication in yeast nuclear extracts

artículo científico publicado en 1999

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling

DDK has a primary role in processing stalled replication forks to initiate downstream checkpoint signaling

DDR Inc., one business, two associates

artículo científico publicado en 2018

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

artículo científico publicado en 2013

DNA repair in diffuse large B-cell lymphoma: a molecular portrait

artículo científico publicado en 2014

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

artículo científico publicado en 2013

DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.

artículo científico publicado en 2012

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

artículo científico publicado en 2018

Defining replication origin efficiency using DNA fiber assays

scientific article published on January 2010

Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint

artículo científico publicado en 2009

Does interference between replication and transcription contribute to genomic instability in cancer cells?

artículo científico publicado en 2010

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

artículo científico publicado en 2014

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

artículo científico publicado en 2015

Ethanol exposure increases mutation rate through error-prone polymerases

artículo científico publicado en 2020

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

artículo científico publicado en 2010

Genetic and epigenetic determinants of DNA replication origins, position and activation

artículo científico

Histone H3 lysine 56 acetylation and the response to DNA replication fork damage

artículo científico publicado en 2012

Homologous recombination and Mus81 promote replication completion in response to replication fork blockage

artículo científico publicado en 2020

In Vitro DNA Replication in Yeast Nuclear Extracts

scientific article published on 01 July 1999

In vitro DNA replication assays in yeast extracts

artículo científico publicado en 2002

Interference between DNA replication and transcription as a cause of genomic instability

artículo científico publicado en 2012

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

artículo científico publicado en 2009

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading

artículo científico publicado en 2019

Maintenance of fork integrity at damaged DNA and natural pause sites

artículo científico publicado en 2007

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

artículo científico publicado en 2020

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

artículo científico publicado en 2016

Mitotic remodeling of the replicon and chromosome structure

artículo científico publicado en 2005

Molecular dissection of a specific nuclear domain: the chromatin region of the ribosomal gene cluster in Xenopus laevis

artículo científico publicado en 1992

Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains.

artículo científico

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage

scholarly article by Julien Bacal published in November 2018

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

artículo científico publicado en 2005

Multiple roles of replication forks in S phase checkpoints: sensors, effectors and targets.

artículo científico publicado en 2003

New Topoisomerase I mutations are associated with resistance to camptothecin

artículo científico publicado en 2011

New histone supply regulates replication fork speed and PCNA unloading

artículo científico publicado en 2013

New systems for replicating DNA in vitro ⬇️

artículo científico publicado el 1 de junio de 1998

Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches

artículo científico publicado en 2016

Nucleases Acting at Stalled Forks: How to Reboot the Replication Program with a Few Shortcuts

artículo científico publicado en 2017

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

artículo científico publicado en 2013

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

artículo científico publicado en 2002

ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei

scientific article published on 01 June 1997

Overexpression of the Fork Protection Complex: a strategy to tolerate oncogene-induced replication stress in cancer cells

artículo científico publicado en 2019

Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest

artículo científico publicado en 2016

Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast

artículo científico publicado en 2007

RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

artículo científico publicado en 2016

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

artículo científico publicado en 2017

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells

artículo científico publicado en 2010

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together

artículo científico publicado en 2016

Rescuing stalled or damaged replication forks

artículo científico publicado en 2013

Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA

artículo científico publicado en 2008

SAMHD1 acts at stalled replication forks to prevent interferon induction

artículo científico publicado en 2018

SAMHD1 and the innate immune response to cytosolic DNA during DNA replication

scholarly article by Flavie Coquel et al published February 2019 in Current Opinion in Immunology

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

artículo científico publicado en 2013

Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template.

artículo científico publicado en 1998

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

artículo científico publicado en 2018

Short DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolytica

artículo científico publicado en 1999

Signaling pathways of replication stress in yeast

artículo científico publicado en 2016

Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus

artículo científico publicado en 2002

Sir2 takes affirmative action to ensure equal opportunity in replication origin licensing

artículo científico publicado en 2020

Size variation of rDNA clusters in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

artículo científico publicado en 1993

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

scholarly article

The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites

artículo científico publicado en 2006

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

artículo científico publicado en 2009

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages

artículo científico publicado en 2010

The causes of replication stress and their consequences on genome stability and cell fate.

artículo científico publicado en 2014

The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast

artículo científico publicado en 2014

The replication timing program in the hands of two HDACs

artículo científico publicado en 2014

The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

artículo científico publicado en 2003

Think global, act local--how to regulate S phase from individual replication origins.

artículo científico publicado en 2000

Time to be versatile: regulation of the replication timing program in budding yeast

artículo científico

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

artículo científico publicado en 2020

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

artículo científico publicado en 2009

Transcription and replication: breaking the rules of the road causes genomic instability

artículo científico publicado en 2010

Transcription-Replication Conflicts: Orientation Matters

artículo científico publicado en 2017

USP1 Regulates Cellular Senescence by Controlling Genomic Integrity

artículo científico publicado en 2016

Upregulation of error-prone DNA polymerases beta and kappa slows down fork progression without activating the replication checkpoint

artículo científico publicado en 2007

dNTP pools determine fork progression and origin usage under replication stress

artículo científico publicado en 2012

Lista de obras de Philippe Pasero

A 'DNA replication' signature of progression and negative outcome in colorectal cancer

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy

A journey into the nucleus. Conference on Nuclear Structure and Dynamics

A role for the Cdc7 kinase regulatory subunit Dbf4p in the formation of initiation-competent origins of replication

An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes

Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing.

Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response

Anaphase Onset Before Complete DNA Replication with Intact Checkpoint Responses

Caught in the Act: R-Loops Are Cleaved by Structure-Specific Endonucleases to Generate DSBs

Closing the MCM cycle at replication termination sites

Cohesin association to replication sites depends on rad50 and promotes fork restart

Common DNA structural features exhibited by eukaryotic ribosomal gene promoters.

Cyclin B-cdk1 kinase stimulates ORC- and Cdc6-independent steps of semiconservative plasmid replication in yeast nuclear extracts

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling

DDK has a primary role in processing stalled replication forks to initiate downstream checkpoint signaling

DDR Inc., one business, two associates

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

DNA repair in diffuse large B-cell lymphoma: a molecular portrait

DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients.

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

Defining replication origin efficiency using DNA fiber assays

Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint

Does interference between replication and transcription contribute to genomic instability in cancer cells?

Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

Ethanol exposure increases mutation rate through error-prone polymerases

Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.

Genetic and epigenetic determinants of DNA replication origins, position and activation

Histone H3 lysine 56 acetylation and the response to DNA replication fork damage

Homologous recombination and Mus81 promote replication completion in response to replication fork blockage

In Vitro DNA Replication in Yeast Nuclear Extracts

In vitro DNA replication assays in yeast extracts

Interference between DNA replication and transcription as a cause of genomic instability

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading

Maintenance of fork integrity at damaged DNA and natural pause sites

Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication

Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress

Mitotic remodeling of the replicon and chromosome structure

Molecular dissection of a specific nuclear domain: the chromatin region of the ribosomal gene cluster in Xenopus laevis

Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains.

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

Multiple roles of replication forks in S phase checkpoints: sensors, effectors and targets.

New Topoisomerase I mutations are associated with resistance to camptothecin

New histone supply regulates replication fork speed and PCNA unloading

New systems for replicating DNA in vitro ⬇️

Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches

Nucleases Acting at Stalled Forks: How to Reboot the Replication Program with a Few Shortcuts

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase

ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei

Overexpression of the Fork Protection Complex: a strategy to tolerate oncogene-induced replication stress in cancer cells

Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest

Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast

RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together

Rescuing stalled or damaged replication forks

Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA

SAMHD1 acts at stalled replication forks to prevent interferon induction

SAMHD1 and the innate immune response to cytosolic DNA during DNA replication

SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage.

Semi-conservative replication in yeast nuclear extracts requires Dna2 helicase and supercoiled template.

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

Short DNA fragments without sequence similarity are initiation sites for replication in the chromosome of the yeast Yarrowia lipolytica

Signaling pathways of replication stress in yeast

Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus

Sir2 takes affirmative action to ensure equal opportunity in replication origin licensing

Size variation of rDNA clusters in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

The Cullin Rtt101p Promotes Replication Fork Progression through Damaged DNA and Natural Pause Sites

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages

The causes of replication stress and their consequences on genome stability and cell fate.

The histone deacetylases sir2 and rpd3 act on ribosomal DNA to control the replication program in budding yeast