Lista de obras - Francisco Abad-Santos - Dominio Público Uruguay

A simple assay for the simultaneous determination of human plasma albendazole and albendazole sulfoxide levels by high performance liquid chromatography in tandem mass spectrometry with solid-phase extraction.

artículo científico publicado en 2013

ATA homozigosity in the IL-10gene promoter is a risk factor for schizophrenia in Spanish females: a case control study ⬇️

artículo científico publicado el 9 de junio de 2011

Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells

artículo científico publicado en 2005

An eutomer/distomer ratio near unity does not justify non-enantiospecific assay methods in bioequivalence studies.

artículo científico publicado en 2005

Application of pharmacogenomics and other new technologies to drug development

artículo científico publicado en 2013

Assessment of sex differences in pharmacokinetics and pharmacodynamics of amlodipine in a bioequivalence study

artículo científico publicado en 2005

Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease

artículo científico publicado en 2016

Association between psoriasis and polymorphisms in the TNF, IL12B, and IL23R genes in Spanish patients

artículo científico publicado en 2013

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population ⬇️

artículo científico publicado el 3 de enero de 2012

Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children

artículo científico publicado en 2016

Author's Response to: 'Letter to the Editor in Response to: "Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally"'

scientific article published on 24 December 2019

CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis

artículo científico publicado en 2022

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment

artículo científico publicado en 2013

Comparison of gastric endoscopic lesions and tolerability to ibuprofen and ibuprofen-arginate in healthy subjects

artículo científico publicado en 2005

Consumption of Drugs and Nonpharmacological Therapies in Caregivers of Patients with Alzheimer's Disease: A Case-Control Study in Madrid

artículo científico publicado en 2016

DRD2 Taq1A polymorphism modulates prolactin secretion induced by atypical antipsychotics in healthy volunteers

Digoxin level and clinical manifestations as determinants in the diagnosis of digoxin toxicity

artículo científico publicado en 2000

Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.

artículo científico publicado en 2015

Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects

artículo científico publicado en 2020

Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally

scientific article published on 03 September 2019

Effect of Sex, Use of Pantoprazole and Polymorphisms in SLC22A1, ABCB1, CES1, CYP3A5 and CYP2D6 on the Pharmacokinetics and Safety of Dabigatran

scientific article published on 20 June 2020

Effect of Truncating AUC at 12, 24 and 48 hr When Evaluating the Bioequivalence of Drugs with a Long Half-Life.

artículo científico publicado en 2015

Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

artículo científico publicado en 2020

Effect of gender and CYP2C9 and CYP2C8 polymorphisms on the pharmacokinetics of ibuprofen enantiomers

artículo científico publicado en 2015

Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions

artículo científico publicado en 2004

Effect of polymorphisms on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates

scientific article published on 22 April 2020

Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

artículo científico publicado en 2010

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects

artículo científico publicado en 2018

Effects of dotarizine and flunarizine on chromaffin cell viability and cytosolic Ca2+.

artículo científico publicado en 1999

Epigenetic biomarkers associated with antitumour necrosis factor drug response in moderate-to-severe psoriasis.

artículo científico publicado en 2017

Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.

artículo científico publicado en 2010

Evaluation of Voriconazole CYP2C19 Phenotype-Guided Dose Adjustments by Physiologically Based Pharmacokinetic Modeling

scientific article published on 17 September 2020

Evaluation of sex differences in the pharmacokinetics of ranitidine in humans

artículo científico publicado en 1996

Evaluation of the Relationship Between Pharmacokinetics and the Safety of Aripiprazole and Its Cardiovascular Effects in Healthy Volunteers

artículo científico publicado en 2016

Evaluation of the relationship between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, pantoprazole and rabeprazole.

artículo científico publicado en 2014

Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib

artículo científico publicado en 2013

Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers

artículo científico publicado en 2012

Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers

artículo científico publicado en 2004

Gene polymorphisms that can predict response to anti-TNF therapy in patients with psoriasis and related autoimmune diseases

artículo científico publicado en 2013

Genetic variants of interferon-stimulated genes and IL-28B as host prognostic factors of response to combination treatment for chronic hepatitis C.

artículo científico publicado en 2011

Genetics of psoriasis and pharmacogenetics of biological drugs

artículo científico publicado en 2013

IL17RA gene variants and anti-TNF response among psoriasis patients.

artículo científico publicado en 2016

Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19)

artículo científico publicado en 2020

Improvement and validation of a high-performance liquid chromatography in tandem mass spectrometry method for monitoring of omeprazole in plasma.

artículo científico publicado en 2015

In vitro models for the study of nerve lesions and potential neuroprotective drugs

artículo científico publicado el 1 de diciembre de 1997

Influence of CYP2B6 activity score on the pharmacokinetics and safety of single dose efavirenz in healthy volunteers

scientific article published on 18 October 2019

Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers

artículo científico publicado en 2008

Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers

artículo científico publicado en 2009

Investigation on the Existence of Sex-By-Formulation Interaction in Bioequivalence Trials

artículo científico publicado en 2019

Involvement of CYP2D6 and CYP2B6 on tramadol pharmacokinetics

artículo científico publicado en 2020

Meta-analysis of clarithromycin compared to other antibiotics for the treatment of lower respiratory tract infections

artículo científico publicado en 2003

Meta-analysis of clarithromycin compared with other antimicrobial drugs in the treatment of upper respiratory tract infections

artículo científico publicado en 2003

Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics

artículo científico publicado en 2020

New immune system genetic polymorphisms associated with moderate-to-severe plaque psoriasis: a case-control study

artículo científico publicado en 2015

New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.

artículo científico publicado en 2016

Nimodipine transfer into human breast milk and cerebrospinal fluid

scientific article published on 01 February 1996

Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells

artículo científico publicado en 1999

Paradoxical psoriasiform reactions to anti-TNFα drugs are associated with genetic polymorphisms in patients with psoriasis

artículo científico publicado en 2015

Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers

artículo científico publicado en 2013

Pharmacogenetic relevance of the CYP2C9*3 allele in a tenoxicam bioequivalence study performed on Spaniards.

artículo científico publicado en 2008

Pharmacogenetic studies assessment in clinical research: Four issues, four opinions

artículo científico publicado en 2010

Pharmacogenetics Update on Biologic Therapy in Psoriasis

artículo científico publicado en 2020

Pharmacogenetics and Pharmacogenomics in Moderate-to-Severe Psoriasis

artículo científico publicado en 2017

Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.

artículo científico publicado en 2017

Pharmacogenetics of quetiapine in healthy volunteers: association with pharmacokinetics, pharmacodynamics, and adverse effects

artículo científico publicado en 2015

Pharmacogenetics of topical and systemic treatment of psoriasis.

artículo científico

Pharmacokinetics and pharmacodynamics of a single bolus of propofol 2% in healthy volunteers

artículo científico publicado en 2003

Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

artículo científico publicado en 2015

Polymorphisms in CYP1A2, CYP2C9 and ABCB1 affect agomelatine pharmacokinetics

scientific article published on 21 February 2019

Polymorphisms in CYP2D6 have a greater effect on variability of risperidone pharmacokinetics than gender

article published in 2015

Polymorphisms influencing olanzapine metabolism and adverse effects in healthy subjects

artículo científico publicado en 2013

Regulation of bronchial tone in chronic obstructive pulmonary disease (COPD): role of muscarinic receptors

artículo científico publicado en 2003

Retroperitoneal haematoma in a patient treated with acenocoumarol, phenytoin and paroxetine

artículo científico publicado en 1995

Safety and cardiovascular effects of multiple-dose administration of aripiprazole and olanzapine in a randomised clinical trial

artículo científico publicado en 2020

The comparative hemodynamic effects of intravenous IQB-9302 and bupivacaine in anesthetized rats

artículo científico publicado en 2004

The effect of CYP2D6 variation on antipsychotic-induced hyperprolactinaemia: a systematic review and meta-analysis

artículo científico publicado en 2020

The polymorphism rs763780 in the IL-17F gene is associated with response to biological drugs in patients with psoriasis.

artículo científico publicado en 2015

The relationship between tumour necrosis factor (TNF)-α promoter and IL12B/IL-23R genes polymorphisms and the efficacy of anti-TNF-α therapy in psoriasis: a case-control study

artículo científico publicado en 2013

Toward a clinical practice guide in pharmacogenomics testing for functional polymorphisms of drug-metabolizing enzymes. Gene/drug pairs and barriers perceived in Spain

artículo científico publicado en 2012

Treatment of mild cognitive impairment: value of citicoline

artículo científico publicado en 2002

Ulnar nerve block induced by the new local anesthetic IQB-9302 in healthy volunteers: a comparison with bupivacaine

artículo científico publicado en 2001

Use of Exposure Data to Establish Causality in Drug–Adverse Event Relationships: An Example with Desvenlafaxine

artículo científico publicado en 2024

Use of non-specific intravenous human immunoglobulins in Spanish hospitals; need for a hospital protocol

artículo científico publicado en 2010

Use of pharmacogenetics in bioequivalence studies to reduce sample size: an example with mirtazapine and CYP2D6.

artículo científico publicado en 2012

Utility of Pilot Studies for Predicting Ratios and Intrasubject Variability in High-Variability Drugs.

artículo científico publicado en 2016

Utility of assessing thiopurine S-methyltransferase polymorphisms before azathioprine therapy.

artículo científico publicado en 2012

Validation of a genotyping method for analysis of TPMT polymorphisms.

artículo científico publicado en 2012

[Cost-effectiveness analysis of the eradication of Helicobacter pylori as treatment for duodenal ulcer]

artículo científico publicado en 1998

[Electronic medical record in clinical trials of effectiveness of drugs integrated in clinical practice]

scientific article published on 23 April 2015

[New antiviral agents in chronic viral hepatitis]

artículo científico publicado en 1998

[Regulation and evaluation of clinical trials of cell therapy]

artículo científico publicado en 2010

[Study of genetic polymorphisms in the tumor necrosis factor α promoter region in Spanish patients with psoriasis]

artículo científico publicado en 2011

[The current state of citicholine in cerebral ischemia]

scientific article published on 01 April 2000

Lista de obras de Francisco Abad-Santos

A simple assay for the simultaneous determination of human plasma albendazole and albendazole sulfoxide levels by high performance liquid chromatography in tandem mass spectrometry with solid-phase extraction.

ATA homozigosity in the IL-10gene promoter is a risk factor for schizophrenia in Spanish females: a case control study ⬇️

Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells

An eutomer/distomer ratio near unity does not justify non-enantiospecific assay methods in bioequivalence studies.

Application of pharmacogenomics and other new technologies to drug development

Assessment of sex differences in pharmacokinetics and pharmacodynamics of amlodipine in a bioequivalence study

Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease

Association between psoriasis and polymorphisms in the TNF, IL12B, and IL23R genes in Spanish patients

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population ⬇️

Attention deficit hyperactivity disorder: genetic association study in a cohort of Spanish children

Author's Response to: 'Letter to the Editor in Response to: "Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally"'

CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis

CYP2D6 poor metabolizer status might be associated with better response to risperidone treatment

Comparison of gastric endoscopic lesions and tolerability to ibuprofen and ibuprofen-arginate in healthy subjects

Consumption of Drugs and Nonpharmacological Therapies in Caregivers of Patients with Alzheimer's Disease: A Case-Control Study in Madrid

DRD2 Taq1A polymorphism modulates prolactin secretion induced by atypical antipsychotics in healthy volunteers

Digoxin level and clinical manifestations as determinants in the diagnosis of digoxin toxicity

Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.

Effect of Cytochrome P450 and ABCB1 Polymorphisms on Imatinib Pharmacokinetics After Single-Dose Administration to Healthy Subjects

Effect of Polymorphisms in CYP2C9 and CYP2C19 on the Disposition, Safety and Metabolism of Progesterone Administrated Orally or Vaginally

Effect of Sex, Use of Pantoprazole and Polymorphisms in SLC22A1, ABCB1, CES1, CYP3A5 and CYP2D6 on the Pharmacokinetics and Safety of Dabigatran

Effect of Truncating AUC at 12, 24 and 48 hr When Evaluating the Bioequivalence of Drugs with a Long Half-Life.

Effect of food on the pharmacokinetics of omeprazole, pantoprazole and rabeprazole

Effect of gender and CYP2C9 and CYP2C8 polymorphisms on the pharmacokinetics of ibuprofen enantiomers

Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions

Effect of polymorphisms on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates

Effects of CYP2D6 genotype on the pharmacokinetics, pharmacodynamics, and safety of risperidone in healthy volunteers

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects

Effects of dotarizine and flunarizine on chromaffin cell viability and cytosolic Ca2+.

Epigenetic biomarkers associated with antitumour necrosis factor drug response in moderate-to-severe psoriasis.

Evaluating a newly developed pharmacogenetic array: screening in a Spanish population.

Evaluation of Voriconazole CYP2C19 Phenotype-Guided Dose Adjustments by Physiologically Based Pharmacokinetic Modeling

Evaluation of sex differences in the pharmacokinetics of ranitidine in humans

Evaluation of the Relationship Between Pharmacokinetics and the Safety of Aripiprazole and Its Cardiovascular Effects in Healthy Volunteers

Evaluation of the relationship between polymorphisms in CYP2C19 and the pharmacokinetics of omeprazole, pantoprazole and rabeprazole.

Evaluation of the relationship between polymorphisms in CYP2C8 and CYP2C9 and the pharmacokinetics of celecoxib

Evaluation of the relationship between sex, polymorphisms in CYP2C8 and CYP2C9, and pharmacokinetics of angiotensin receptor blockers

Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers

Gene polymorphisms that can predict response to anti-TNF therapy in patients with psoriasis and related autoimmune diseases

Genetic variants of interferon-stimulated genes and IL-28B as host prognostic factors of response to combination treatment for chronic hepatitis C.

Genetics of psoriasis and pharmacogenetics of biological drugs

IL17RA gene variants and anti-TNF response among psoriasis patients.

Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19)

Improvement and validation of a high-performance liquid chromatography in tandem mass spectrometry method for monitoring of omeprazole in plasma.

In vitro models for the study of nerve lesions and potential neuroprotective drugs

Influence of CYP2B6 activity score on the pharmacokinetics and safety of single dose efavirenz in healthy volunteers

Influence of CYP2C8 and CYP2C9 polymorphisms on pharmacokinetic and pharmacodynamic parameters of racemic and enantiomeric forms of ibuprofen in healthy volunteers

Influence of sex and CYP2D6 genotype on mirtazapine disposition, evaluated in Spanish healthy volunteers

Investigation on the Existence of Sex-By-Formulation Interaction in Bioequivalence Trials

Involvement of CYP2D6 and CYP2B6 on tramadol pharmacokinetics

Meta-analysis of clarithromycin compared to other antibiotics for the treatment of lower respiratory tract infections

Meta-analysis of clarithromycin compared with other antimicrobial drugs in the treatment of upper respiratory tract infections

Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics

New immune system genetic polymorphisms associated with moderate-to-severe plaque psoriasis: a case-control study

New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.

Nimodipine transfer into human breast milk and cerebrospinal fluid

Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells

Paradoxical psoriasiform reactions to anti-TNFα drugs are associated with genetic polymorphisms in patients with psoriasis

Pharmacodynamic genetic variants related to antipsychotic adverse reactions in healthy volunteers

Pharmacogenetic relevance of the CYP2C9*3 allele in a tenoxicam bioequivalence study performed on Spaniards.

Pharmacogenetic studies assessment in clinical research: Four issues, four opinions

Pharmacogenetics Update on Biologic Therapy in Psoriasis

Pharmacogenetics and Pharmacogenomics in Moderate-to-Severe Psoriasis

Pharmacogenetics of methylphenidate in childhood attention-deficit/hyperactivity disorder: long-term effects.

Pharmacogenetics of quetiapine in healthy volunteers: association with pharmacokinetics, pharmacodynamics, and adverse effects

Pharmacogenetics of topical and systemic treatment of psoriasis.

Pharmacokinetics and pharmacodynamics of a single bolus of propofol 2% in healthy volunteers

Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

Polymorphisms in CYP1A2, CYP2C9 and ABCB1 affect agomelatine pharmacokinetics

Polymorphisms in CYP2D6 have a greater effect on variability of risperidone pharmacokinetics than gender

Polymorphisms influencing olanzapine metabolism and adverse effects in healthy subjects

Regulation of bronchial tone in chronic obstructive pulmonary disease (COPD): role of muscarinic receptors

Retroperitoneal haematoma in a patient treated with acenocoumarol, phenytoin and paroxetine

Safety and cardiovascular effects of multiple-dose administration of aripiprazole and olanzapine in a randomised clinical trial

The comparative hemodynamic effects of intravenous IQB-9302 and bupivacaine in anesthetized rats

The effect of CYP2D6 variation on antipsychotic-induced hyperprolactinaemia: a systematic review and meta-analysis

The polymorphism rs763780 in the IL-17F gene is associated with response to biological drugs in patients with psoriasis.

The relationship between tumour necrosis factor (TNF)-α promoter and IL12B/IL-23R genes polymorphisms and the efficacy of anti-TNF-α therapy in psoriasis: a case-control study