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Lista de obras de Folkert W Asselbergs

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

artículo científico publicado en 2015

A Simple and Computationally Efficient Approach to Multifactor Dimensionality Reduction Analysis of Gene-Gene Interactions for Quantitative Traits

artículo científico publicado en 2013

A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass

artículo científico publicado en 2019

A gene-centric study of common carotid artery remodelling

artículo científico publicado en 2012

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

artículo científico publicado en 2016

A genomic exploration identifies mechanisms that may explain adverse cardiovascular effects of COX-2 inhibitors

artículo científico publicado en 2017

A mutation update for the FLNC gene in myopathies and cardiomyopathies

scientific article published on 29 February 2020

A role for CETP TaqIB polymorphism in determining susceptibility to atrial fibrillation: a nested case control study

artículo científico publicado en 2006

A systematic analysis of genetic dilated cardiomyopathy reveals numerous ubiquitously expressed and muscle-specific genes

artículo científico publicado en 2015

A systematic comparison of cardiovascular magnetic resonance and high resolution histological fibrosis quantification in a chronic porcine infarct model

artículo científico publicado en 2017

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

artículo científico publicado en 2014

Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition

artículo científico publicado en 2008

Acute intermittent porphyria as a cause of respiratory failure: case report

artículo científico publicado en 2009

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

artículo científico publicado en 2017

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

artículo científico publicado en 2016

An Independent Filter for Gene Set Testing Based on Spectral Enrichment

artículo científico publicado en 2015

An agenda-setting paper on data sharing platforms: euCanSHare workshop

artículo científico publicado en 2021

Angiotensin converting enzyme inhibition in cardiovascular risk populations: a practical approach to identify the patient who will benefit most

artículo científico publicado en 2007

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

artículo científico publicado en 2022

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

artículo científico publicado en 2014

Antineutrophil cytoplasmatic antibodies in patients with premature atherosclerosis: prevalence and association with risk factors

artículo científico publicado en 2002

Assessing the prognostic value of coronary endothelial function in patients referred for a first coronary angiogram

artículo científico publicado en 2004

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

artículo científico publicado en 2014

Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies

artículo científico publicado en 2011

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

artículo científico publicado en 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

artículo científico publicado en 2020

Association of renal function with cardiac calcifications in older adults: the cardiovascular health study

scientific article published on 07 October 2008

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

BIO FOr CARE: biomarkers of hypertrophic cardiomyopathy development and progression in carriers of Dutch founder truncating MYBPC3 variants-design and status

artículo científico publicado en 2021

Big Data in Cardiovascular Disease

artículo científico

Bioinformatics challenges for genome-wide association studies

artículo científico publicado en 2010

Biomarkers of Coronary Artery Disease Differ Between Asians and Caucasians in the General Population

artículo científico

C-reactive protein and microalbuminuria are associated with atrial fibrillation

artículo científico publicado en 2005

C-reactive protein and microalbuminuria differ in their associations with various domains of vascular disease

artículo científico publicado en 2004

CYP2C19 genotype-guided antiplatelet therapy in ST-segment elevation myocardial infarction patients-Rationale and design of the Patient Outcome after primary PCI (POPular) Genetics study

artículo científico publicado en 2014

Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction

artículo científico publicado en 2017

Cardiovascular disease risk factors in Ghana during the rural-to-urban transition: A cross-sectional study

artículo científico publicado en 2016

Cardiovascular genetics: technological advancements and applicability for dilated cardiomyopathy

artículo científico

Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems

artículo científico publicado en 2010

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis

artículo científico publicado en 2014

Cell Therapy, a Novel Remedy for Dilated Cardiomyopathy? A Systematic Review ⬇️

artículo científico publicado el 1 de julio de 2013

Change in prescription pattern as a potential marker for adverse drug reactions of angiotensin converting enzyme inhibitors

artículo científico publicado en 2015

Characteristic adaptations of the extracellular matrix in dilated cardiomyopathy

artículo científico publicado en 2016

Cholesteryl Ester Transfer Protein Polymorphisms, Statin Use, and Their Impact on Cholesterol Levels and Cardiovascular Events

scientific article published on 30 September 2013

Clinical impact of vasomotor function assessment and the role of ACE-inhibitors and statins

artículo científico publicado en 2005

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

artículo científico publicado en 2016

Cohort profile of BIOMArCS: the BIOMarker study to identify the Acute risk of a Coronary Syndrome-a prospective multicentre biomarker study conducted in the Netherlands

artículo científico publicado en 2016

Common Variants Associated With <i>OSMR</i> Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

artículo científico publicado en 2021

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

artículo científico publicado en 2009

Common variants associated with blood lipid levels do not affect carotid plaque composition

artículo científico publicado en 2015

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Comparing clinical performance of current implantable cardioverter-defibrillator implantation recommendations in arrhythmogenic right ventricular cardiomyopathy

artículo científico publicado en 2022

Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies

artículo científico publicado en 2015

Continuation of angiotensin converting enzyme inhibitor therapy, in spite of occurrence of angioedema

artículo científico publicado en 2015

Coronary vasomotor response is related to the angiographic extent of coronary sclerosis in patients with stable angina pectoris

artículo científico publicado en 2004

Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy

artículo científico publicado en 2015

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Correlates of endothelial function and their relationship with inflammation in patients with familial hypercholesterolaemia

artículo científico publicado en 2003

Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: A pharmacoeconomic analysis linked to the prevention of renal and vascular endstage disease (PREVEND) study and the prevention of r

article

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

artículo científico publicado en 2016

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Determinants of angiotensin-converting enzyme inhibitor (ACEI) intolerance and angioedema in the UK Clinical Practice Research Datalink

artículo científico publicado en 2016

Determination of vessel size: a putative framework to assess clinical outcome

artículo científico publicado en 2004

Differences between familial and sporadic dilated cardiomyopathy: ESC EORP Cardiomyopathy & Myocarditis registry

artículo científico publicado en 2020

Directional dominance on stature and cognition in diverse human populations

artículo científico publicado en 2015

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

artículo científico publicado en 2017

Discovery of novel heart rate-associated loci using the Exome Chip

artículo científico publicado en 2017

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

artículo científico publicado en 2020

Distinct fibrosis pattern in desmosomal and phospholamban mutation carriers in hereditary cardiomyopathies.

artículo científico publicado en 2017

Dominant missense mutations in ABCC9 cause Cantú syndrome.

artículo científico publicado en 2012

Dosing algorithms for vitamin K antagonists across VKORC1 and CYP2C9 genotypes

artículo científico publicado en 2017

ENerGetIcs in hypertrophic cardiomyopathy: traNslation between MRI, PET and cardiac myofilament function (ENGINE study).

artículo científico publicado en 2013

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Early health technology assessments in pharmacogenomics: a case example in cardiovascular drugs.

artículo científico publicado en 2017

Effect of Metformin on Metabolites and Relation With Myocardial Infarct Size and Left Ventricular Ejection Fraction After Myocardial Infarction

artículo científico

Effect of Monocyte-to-Lymphocyte Ratio on Heart Failure Characteristics and Hospitalizations in a Coronary Angiography Cohort

artículo científico publicado en 2017

Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria

artículo científico publicado en 2008

Effect of statins on atrial fibrillation: collaborative meta-analysis of published and unpublished evidence from randomised controlled trials

scientific article published on 16 March 2011

Effect of withdrawal of pravastatin therapy on C-reactive protein and low-density lipoprotein cholesterol

artículo científico publicado en 2007

Effects of C-Reactive Protein and Cholesterol on Responsiveness In Vitro of the Internal Thoracic Artery to Angiotensin II in Patients Having Coronary Artery Bypass Grafting

artículo científico publicado en 2006

Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria

artículo científico publicado en 2004

Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria

artículo científico publicado en 2005

Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease

artículo científico publicado en 2007

Epistatic effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels.

artículo científico publicado en 2007

Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population.

artículo científico publicado en 2011

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Ethnicity Modifies Associations between Cardiovascular Risk Factors and Disease Severity in Parallel Dutch and Singapore Coronary Cohorts

artículo científico publicado en 2015

Exome Array Analysis of Susceptibility to Pneumococcal Meningitis

artículo científico publicado en 2016

Exome-Wide Association Analysis of Coronary Artery Disease in the Kingdom of Saudi Arabia Population

artículo científico publicado en 2016

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Extending the use of GWAS data by combining data from different genetic platforms.

artículo científico publicado en 2017

Extensive Association of Common Disease Variants with Regulatory Sequence.

artículo científico publicado en 2016

FTO genotype is associated with phenotypic variability of body mass index

artículo científico publicado en 2012

Family history and polygenic risk of cardiovascular disease: Independent factors associated with secondary cardiovascular events in patients undergoing carotid endarterectomy

artículo científico publicado en 2020

Fatty acid oxidation flux predicts the clinical severity of VLCAD deficiency

artículo científico publicado en 2015

Framingham score and microalbuminuria: combined future targets for primary prevention?

artículo científico publicado en 2004

Functional characteristics of coronary vasomotor function following intramyocardial gene therapy with naked DNA encoding for vascular endothelial growth factor165.

artículo científico publicado en 2005

Gender differences in health-related quality of life in patients undergoing coronary angiography

artículo científico publicado en 2015

Gender gap in acute coronary heart disease: Myth or reality? ⬇️

artículo científico publicado el 26 de febrero de 2012

Gender-specific correlations of plasminogen activator inhibitor-1 and tissue plasminogen activator levels with cardiovascular disease-related traits

artículo científico publicado en 2006

Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype

artículo científico publicado en 2017

Gene ontology analysis of pairwise genetic associations in two genome-wide studies of sporadic ALS

artículo científico publicado en 2012

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

artículo científico publicado en 2014

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations

artículo científico publicado en 2012

Gene-gene interactions betweenHNF4AandKCNJ11in predicting Type 2 diabetes in women

article

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

artículo científico publicado en 2020

Genetic Effects on the Correlation Structure of CVD Risk Factors: Exome-Wide Data From a Ghanaian Population

artículo científico publicado en 2017

Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience

article

Genetic analysis of emerging risk factors in coronary artery disease.

artículo científico publicado en 2016

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic architecture of tissue-type plasminogen activator and plasminogen activator inhibitor-1.

artículo científico publicado en 2008

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

artículo científico publicado en 2014

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

artículo científico publicado en 2012

Genetic evidence of assortative mating in humans

scholarly article

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

artículo científico publicado en 2017

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

artículo científico publicado en 2015

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis

artículo científico publicado en 2014

Genetic variation within the Y chromosome is not associated with histological characteristics of the atherosclerotic carotid artery or aneurysmal wall

artículo científico publicado en 2017

Genetics and tailored therapy in cardiovascular disease ⬇️

artículo científico publicado el 1 de enero de 2012

Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population

artículo científico publicado en 2015

Genetics of coronary artery disease: genome-wide association studies and beyond

artículo científico publicado en 2012

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank

artículo científico publicado en 2020

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

artículo científico publicado en 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association studies identify genetic loci for low von Willebrand factor levels

artículo científico publicado en 2016

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

artículo científico publicado en 2012

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

artículo científico publicado en 2014

Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

artículo científico publicado en 2020

Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.

artículo científico publicado en 2013

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

scientific article published in Nature Communications

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

artículo científico publicado en 2017

Genotype-guided coumarin dosing: where are we now and where do we need to go next?

artículo científico publicado en 2015

Genotype-specific pathogenic effects in human dilated cardiomyopathy.

artículo científico publicado en 2017

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

artículo científico publicado en 2014

Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk

artículo científico publicado en 2016

Health-related quality of life and outcome in atherosclerosis - Does sex matter?

artículo científico publicado en 2016

Hematological Parameters Improve Prediction of Mortality and Secondary Adverse Events in Coronary Angiography Patients: A Longitudinal Cohort Study

artículo científico publicado en 2015

Hematological Parameters Outperform Plasma Markers in Predicting Long-Term Mortality After Coronary Angiography

artículo científico publicado en 2017

High On-Treatment Platelet Reactivity in Peripheral Arterial Disease: A Pilot Study to Find the Optimal Test and Cut Off Values.

artículo científico publicado en 2016

High prevalence of microalbuminuria in chronic heart failure patients

artículo científico publicado en 2005

High resolution systematic digital histological quantification of cardiac fibrosis and adipose tissue in phospholamban p.Arg14del mutation associated cardiomyopathy

artículo científico publicado en 2014

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

artículo científico publicado en 2016

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

artículo científico publicado en 2015

Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts

artículo científico publicado en 2016

Impact of Selection Bias on Estimation of Subsequent Event Risk

artículo científico publicado en 2017

Impact of carotid atherosclerosis loci on cardiovascular events

artículo científico publicado en 2015

Impact of statins in microalbuminuric subjects with the metabolic syndrome: a substudy of the PREVEND Intervention Trial

artículo científico publicado en 2005

Incremental value of a genetic risk score for the prediction of new vascular events in patients with clinically manifest vascular disease

artículo científico publicado en 2015

Influence of APOE-2 genotype on the relation between adiposity and plasma lipid levels in patients with vascular disease

scientific article published on 20 June 2014

Inter-Ethnic Differences in Quantified Coronary Artery Disease Severity and All-Cause Mortality among Dutch and Singaporean Percutaneous Coronary Intervention Patients

artículo científico publicado en 2015

Interaction between dietary fat intake and the cholesterol ester transfer protein TaqIB polymorphism in relation to HDL-cholesterol concentrations among US diabetic men.

artículo científico publicado en 2007

Interatrial Block Predicts Life‐Threatening Arrhythmias in Dilated Cardiomyopathy

artículo científico publicado en 2022

Interleukin-6 receptor pathways in abdominal aortic aneurysm

scientific article published on 30 October 2012

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

artículo científico publicado en 2012

Intronic Polymorphisms in the CDKN2B-AS1 Gene Are Strongly Associated with the Risk of Myocardial Infarction and Coronary Artery Disease in the Saudi Population.

artículo científico publicado en 2016

Investigation of KIF6 Trp719Arg gene polymorphism in a case-control study of coronary artery disease and non-fatal myocardial infarction in the Eastern Province of Saudi Arabia

artículo científico publicado en 2016

LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease

artículo científico publicado en 2013

Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci

artículo científico publicado en 2012

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

artículo científico publicado en 2023

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

artículo científico publicado en 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

artículo científico publicado en 2012

Letter Regarding Article by Arnlov et al, "Low-Grade Albuminuria and Incidence of Cardiovascular Disease Events in Nonhypertensive and Nondiabetic Individuals"

scientific article published on 01 March 2006

Letters to the Editor

scientific article published on 14 November 2005

Life-long tailoring of management for patients with hypertrophic cardiomyopathy : Awareness and decision-making in changing scenarios.

artículo científico publicado en 2016

Loci influencing blood pressure identified using a cardiovascular gene-centric array

artículo científico publicado en 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array

artículo científico publicado en 2013

Long-term cardiovascular health in adult cancer survivors

artículo científico publicado en 2017

Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT).

artículo científico publicado en 2011

Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects

artículo científico publicado en 2006

Long-term outcome in men and women after CABG; results from the IMAGINE trial

artículo científico publicado en 2015

Loss of Y Chromosome in Blood Is Associated With Major Cardiovascular Events During Follow-Up in Men After Carotid Endarterectomy

artículo científico publicado en 2017

Low-Density Lipoprotein Cholesterol Target Attainment in Patients With Established Cardiovascular Disease: Analysis of Routine Care Data

scientific article published on 02 April 2020

Lower Platelet Reactivity Is Associated with Presentation of Unstable Coronary Artery Disease

artículo científico publicado en 2016

Male-female differences in the genetic regulation of t-PA and PAI-1 levels in a Ghanaian population

artículo científico publicado en 2008

Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

artículo científico publicado en 2021

Measuring and targeting aldosterone and renin in atherosclerosis-a review of clinical data

artículo científico publicado en 2011

Mendelian randomization of blood lipids for coronary heart disease

artículo científico publicado en 2014

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

artículo científico publicado en 2010

Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors

artículo científico publicado en 2016

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

artículo científico publicado en 2019

Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease

artículo científico publicado en 2020

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

scientific article published on 28 September 2020

Mild renal dysfunction is associated with electrocardiographic left ventricular hypertrophy

artículo científico publicado en 2005

Monitoring initial response to Angiotensin-converting enzyme inhibitor-based regimens: an individual patient data meta-analysis from randomized, placebo-controlled trials

artículo científico publicado en 2010

Monocyte gene expression in childhood obesity is associated with obesity and complexity of atherosclerosis in adults

artículo científico publicado en 2017

Multi-omics integration identifies key upstream regulators of pathomechanisms in hypertrophic cardiomyopathy due to truncating MYBPC3 mutations

artículo científico publicado en 2021

Myeloperoxidase polymorphism related to cardiovascular events in coronary artery disease

artículo científico publicado en 2004

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

artículo científico publicado en 2018

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

artículo científico publicado en 2017

Next-generation sequencing of a large gene panel in patients initially diagnosed with idiopathic ventricular fibrillation

artículo científico publicado en 2017

Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels

artículo científico publicado en 2014

Omecamtiv mecarbil: a promising new drug in systolic heart failure

artículo científico publicado en 2011

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

artículo científico publicado en 2016

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

Pharmacogenetics of ACE inhibitor-induced angioedema and cough: a systematic review and meta-analysis

artículo científico

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phospholamban immunostaining is a highly sensitive and specific method for diagnosing phospholamban p.Arg14del cardiomyopathy.

artículo científico publicado en 2017

Plasminogen Activator Inhibitor-1 and Diagnosis of the Metabolic Syndrome in a West African Population.

artículo científico publicado en 2016

Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis

artículo científico publicado en 2014

Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis

scientific article published on 23 April 2020

Prediction of ventricular arrhythmia in phospholamban p.Arg14del mutation carriers-reaching the frontiers of individual risk prediction

artículo científico publicado en 2021

Prevalence and risk of cardiovascular risk factors and events in offspring of patients at high vascular risk and effect of location of parental vascular disease

artículo científico publicado en 2015

Production of Recombinant Proteins in Chinese Hamster Ovary Cells Using A Protein-Free Cell Culture Medium ⬇️

artículo científico publicado el 1 de abril de 1995

Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people ⬇️

artículo científico publicado en 2016

Progress in genetic association studies of plasma lipids.

artículo científico publicado en 2013

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

artículo científico publicado en 2021

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Quantitative Approach to Fragmented QRS in Arrhythmogenic Cardiomyopathy: From Disease towards Asymptomatic Carriers of Pathogenic Variants

artículo científico publicado en 2020

Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events

artículo científico publicado en 2015

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Relation of electrocardiographic abnormalities to levels of serum C-reactive protein

artículo científico publicado en 2003

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

artículo científico publicado en 2017

Relationship between classic vascular risk factors and cumulative recurrent cardiovascular event burden in patients with clinically manifest vascular disease: results from the UCC-SMART prospective cohort study

artículo científico publicado en 2021

Reproductive factors in relation to heart failure in women: A systematic review

artículo científico publicado en 2017

Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records

scientific article published on 07 January 2019

Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with [...]

artículo científico publicado en 2013

Routinely analyzed leukocyte characteristics improve prediction of mortality after coronary angiography

artículo científico publicado en 2015

Rs964184 (APOA5-A4-C3-A1) is related to elevated plasma triglyceride levels, but not to an increased risk for vascular events in patients with clinically manifest vascular disease

artículo científico publicado en 2014

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms

artículo científico publicado en 2009

Serially measured circulating microRNAs and adverse clinical outcomes in patients with acute heart failure

artículo científico publicado en 2017

Seventy-five genetic loci influencing the human red blood cell

artículo científico publicado en 2012

Severity of stable coronary artery disease and its biomarkers differ between men and women undergoing angiography

artículo científico publicado en 2015

Sex matters to the heart: A special issue dedicated to the impact of sex related differences of cardiovascular diseases

artículo científico publicado en 2015

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

artículo científico publicado en 2009

Simultaneous pulmonary, cerebral and coronary emboli

artículo científico publicado en 2011

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

artículo científico publicado en 2019

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

artículo científico publicado en 2017

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease

artículo científico publicado en 2016

The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels

artículo científico publicado en 2011

The COAG and EU-PACT trials: what is the clinical benefit of pharmacogenetic-guided coumarin dosing during therapy initiation?

artículo científico publicado en 2014

The Cardiomyopathy Registry of the EURObservational Research Programme of the European Society of Cardiology: baseline data and contemporary management of adult patients with cardiomyopathies

artículo científico publicado en 2018

The ENCODE project and perspectives on pathways

artículo científico publicado en 2014

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Translational Landscape of the Human Heart

scientific article published on 30 May 2019

The effect of statins on urinary albumin excretion and glomerular filtration rate: results from both a randomized clinical trial and an observational cohort study

artículo científico publicado en 2006

The effects of polymorphisms in genes from the renin–angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels are dependent on environmental context

article

The ethnicity-specific association of biomarkers with the angiographic severity of coronary artery disease

artículo científico publicado en 2016

The gender-specific role of polymorphisms from the fibrinolytic, renin-angiotensin, and bradykinin systems in determining plasma t-PA and PAI-1 levels

artículo científico publicado en 2006

The impact of susceptibility loci for coronary artery disease on other vascular domains and recurrence risk

artículo científico publicado en 2013

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

artículo científico publicado en 2012

The power of genetic diversity in genome-wide association studies of lipids

The relation between the presence of cardiovascular disease and vascular risk factors in offspring and the occurrence of new vascular events in their parents already at high vascular risk

artículo científico publicado en 2015

The temporal pattern of immune and inflammatory proteins prior to a recurrent coronary event in post-acute coronary syndrome patients

artículo científico publicado en 2018

The tip of the iceberg: challenges of accessing hospital electronic health record data for biological data mining

artículo científico publicado en 2016

Thirty years of heart transplantation at the University Medical Centre Utrecht

artículo científico publicado en 2017

Thrombospondin-4 Ala387Pro polymorphism is not associated with vascular function and risk of coronary heart disease in US men and women

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

artículo científico publicado en 2015

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

artículo científico publicado en 2016

Translation of oncogenic virus RNA in Xenopus laevis oocytes ⬇️

artículo científico publicado el 26 de febrero de 1976

Truncating Titin ( TTN) Variants in Chemotherapy-Induced Cardiomyopathy

artículo científico publicado en 2017

Uniform data collection in routine clinical practice in cardiovascular patients for optimal care, quality control and research: The Utrecht Cardiovascular Cohort

artículo científico publicado en 2017

Variants in ALOX5, ALOX5AP and LTA4H are not associated with atherosclerotic plaque phenotypes: the Athero-Express Genomics Study

artículo científico publicado en 2015

Vascular endothelial growth factor: the link between cardiovascular risk factors and microalbuminuria?

artículo científico publicado en 2004

Women Undergoing Coronary Angiography for Myocardial Infarction or Who Present With Multivessel Disease Have a Poorer Prognosis Than Men.

artículo científico

Worsening renal function and prognosis in heart failure: systematic review and meta-analysis.

artículo científico publicado en 2007

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