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Lista de obras de Spiros C Denaxas

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service

scientific article published on 20 May 2019

A novel framework for assessing metadata quality in epidemiological and public health research settings

artículo científico publicado en 2016

A novel metadata management model to capture consent for record linkage in longitudinal research studies.

artículo científico publicado en 2017

A population-based study of 92 clinically recognized risk factors for heart failure: co-occurrence, prognosis and preventive potential

artículo científico publicado en 2022

A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems

artículo científico publicado en 2020

A semi-supervised approach for rapidly creating clinical biomarker phenotypes in the UK Biobank using different primary care EHR and clinical terminology systems.

artículo científico publicado en 2020

Accuracy of Patient Self-Report of Stroke: A Systematic Review from the UK Biobank Stroke Outcomes Group

artículo científico publicado en 2015

Allergic disease, corticosteroid use, and risk of Hodgkin lymphoma: A United Kingdom nationwide case-control study

artículo científico publicado en 2019

An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. ⬇️

artículo científico publicado en 2018

Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records

scientific article published on 01 December 2019

Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study

artículo científico publicado en 2014

Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records.

artículo científico publicado en 2017

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England

artículo científico publicado en 2022

Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank

scientific article published on 21 June 2019

Avoidable flaws in observational analyses: an application to statins and cancer

artículo científico publicado en 2019

Big biomedical data and cardiovascular disease research: opportunities and challenges.

artículo científico publicado en 2015

Big data from electronic health records for early and late translational cardiovascular research: challenges and potential.

artículo científico publicado en 2017

Bleeding in cardiac patients prescribed antithrombotic drugs: electronic health record phenotyping algorithms, incidence, trends and prognosis

scientific article published on 20 November 2019

Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

artículo científico publicado en 2014

Causes of death among homeless people: a population-based cross-sectional study of linked hospitalisation and mortality data in England

article

Clarithromycin and endoscopic sinus surgery for adults with chronic rhinosinusitis with and without nasal polyps: study protocol for the MACRO randomised controlled trial.

artículo científico publicado en 2019

Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study ⬇️

artículo científico publicado en 2018

Comparing and Contrasting A Priori and A Posteriori Generalizability Assessment of Clinical Trials on Type 2 Diabetes Mellitus.

artículo científico publicado en 2017

Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study

artículo científico publicado en 2013

Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database

Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER)

artículo científico publicado en 2012

Data-driven identification of ageing-related diseases from electronic health records

artículo científico publicado en 2021

Defining Disease Phenotypes in Primary Care Electronic Health Records by a Machine Learning Approach: A Case Study in Identifying Rheumatoid Arthritis

artículo científico publicado en 2016

Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation

artículo científico publicado en 2014

Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men. ⬇️

artículo científico publicado en 2016

Desiderata for the development of next-generation electronic health record phenotype libraries

artículo científico publicado en 2021

Discussion of "Combining Health Data Uses to Ignite Health System Learning".

artículo científico publicado en 2015

Engaging with the clinical data transparency initiative: a view from the National Institute for Cardiovascular Outcomes Research (NICOR).

artículo científico publicado en 2012

Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study

artículo científico publicado en 2020

Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients ⬇️

artículo científico publicado en 2017

Evaluation of Semantic Web Technologies for Storing Computable Definitions of Electronic Health Records Phenotyping Algorithms.

artículo científico publicado en 2017

Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort

artículo científico publicado en 2022

Expert panel process to optimise the design of a randomised controlled trial in chronic rhinosinusitis (the MACRO programme)

scientific article published on 23 April 2019

Extracting diagnoses and investigation results from unstructured text in electronic health records by semi-supervised machine learning

artículo científico publicado en 2012

Feasibility and impact of a computerised clinical decision support system on investigation and initial management of new onset chest pain: a mixed methods study

artículo científico publicado en 2015

Feasibility study of hospital antimicrobial stewardship analytics using electronic health records

artículo científico publicado en 2021

Flipping the odds of drug development success through human genomics

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1937360 people in England: lifetime risks and implications for risk prediction.

artículo científico publicado en 2014

Hospital bed capacity and usage across secondary healthcare providers in England during the first wave of the COVID-19 pandemic: a descriptive analysis

artículo científico publicado en 2021

How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People ⬇️

artículo científico publicado en 2015

Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records

article

Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study

artículo científico publicado en 2021

Impact of baseline cases of cough and fever on UK COVID-19 diagnostic testing rates: estimates from the Bug Watch community cohort study

artículo científico publicado en 2020

Improving the odds of drug development success through human genomics: modelling study

scientific article published on 11 December 2019

Influenza infection and risk of acute myocardial infarction in England and Wales: a CALIBER self-controlled case series study

artículo científico publicado en 2012

Integrating Bio-ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes

artículo científico

Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource

artículo científico publicado en 2021

Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study

artículo científico publicado en 2016

Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease

artículo científico publicado en 2018

Metformin use and cardiovascular outcomes after acute myocardial infarction in patients with type 2 diabetes: a cohort study

scientific article published on 09 December 2019

Methods for Enhancing the Reproducibility of Observational Research Using Electronic Health Records: Preliminary Findings from the CALIBER Resource

Methods for enhancing the reproducibility of biomedical research findings using electronic health records

artículo científico publicado en 2017

Natural language processing for disease phenotyping in UK primary care records for research: a pilot study in myocardial infarction and death

artículo científico

Net clinical benefit of warfarin in individuals with atrial fibrillation across stroke risk and across primary and secondary care.

artículo científico publicado en 2016

Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study

artículo científico publicado en 2017

On the Accuracy and Scalability of Probabilistic Data Linkage Over the Brazilian 114 Million Cohort.

artículo científico publicado en 2018

Outcomes of specialist discharge coordination and intermediate care schemes for patients who are homeless: analysis protocol for a population-based historical cohort

artículo científico publicado en 2017

Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors ⬇️

artículo científico publicado en 2017

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Phenotyping UK Electronic Health Records from 15 Million Individuals for Precision Medicine: The CALIBER Resource

artículo científico publicado en 2019

Prognosis of undiagnosed chest pain: linked electronic health record cohort study

artículo científico publicado en 2017

Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people ⬇️

artículo científico publicado en 2016

Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients.

artículo científico publicado en 2013

Prolonged dual antiplatelet therapy in stable coronary disease: comparative observational study of benefits and harms in unselected versus trial populations ⬇️

artículo científico publicado en 2016

Reply

Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records

scientific article published on 07 January 2019

Risk of mortality and cardiovascular events following macrolide prescription in chronic rhinosinusitis patients: a cohort study using linked primary care electronic health records

scientific article published on 01 August 2019

Scoring and summarising gene product clusters using the Gene Ontology.

artículo científico

Serotonin reuptake inhibitors and mortality in epilepsy: A linked primary-care cohort study

artículo científico publicado en 2017

Socioeconomic deprivation and regional variation in Hodgkin's lymphoma incidence in the UK: a population-based cohort study of 10 million individuals

artículo científico publicado en 2019

Socioeconomic deprivation and the incidence of 12 cardiovascular diseases in 1.9 million women and men: implications for risk prediction and prevention.

artículo científico publicado en 2014

Subtypes of atrial fibrillation with concomitant valvular heart disease derived from electronic health records: phenotypes, population prevalence, trends and prognosis

artículo científico publicado en 2019

The relationship between sleep duration, cognition and dementia: a Mendelian randomization study

scientific article published on 01 June 2019

The tip of the iceberg: challenges of accessing hospital electronic health record data for biological data mining

artículo científico publicado en 2016

Time spent at blood pressure target and the risk of death and cardiovascular diseases ⬇️

artículo científico publicado en 2018

Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people

artículo científico publicado en 2015

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people

artículo científico publicado en 2014

Type and timing of heralding in ST-elevation and non-ST-elevation myocardial infarction: an analysis of prospectively collected electronic healthcare records linked to the national registry of acute coronary syndromes

artículo científico publicado en 2013

UK phenomics platform for developing and validating EHR phenotypes: CALIBER

UK phenomics platform for developing and validating electronic health record phenotypes: CALIBER

artículo científico publicado en 2019

Use of electronic health records to ascertain, validate and phenotype acute myocardial infarction: A systematic review and recommendations

artículo científico

Using big data from health records from four countries to evaluate chronic disease outcomes: a study in 114 364 survivors of myocardial infarction. ⬇️

artículo científico publicado en 2016

Using nationwide ‘big data’ from linked electronic health records to help improve outcomes in cardiovascular diseases: 33 studies using methods from epidemiology, informatics, economics and social science in the ClinicAl disease research using LInke

White cell count in the normal range and short-term and long-term mortality: international comparisons of electronic health record cohorts in England and New Zealand

artículo científico publicado en 2017

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