Lista de obras - Angel Cedazo-Minguez - Dominio Público Uruguay

24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis

artículo científico publicado en 2019

27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons

artículo científico publicado en 2019

27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.

artículo científico publicado en 2017

27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

artículo científico publicado en 2014

5-HT1B and other related serotonergic proteins are altered in APPswe mutation.

artículo científico publicado en 2015

A new metabolomic workflow for early detection of Alzheimer's disease

artículo científico publicado en 2013

Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro

artículo científico publicado en 2008

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain

artículo científico publicado en 2008

Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ Productions.

artículo científico publicado en 2016

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

artículo científico publicado en 2014

Analysis of chiral amino acids in cerebrospinal fluid samples linked to different stages of Alzheimer disease.

artículo científico publicado en 2011

Androgen induction of prostate cancer cell invasion is mediated by ezrin.

artículo científico publicado en 2006

Anthocyanins protect from complex I inhibition and APPswe mutation through modulation of the mitochondrial fission/fusion pathways

artículo científico publicado en 2016

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.

artículo científico publicado en 2007

Apolipoprotein E and beta A4-amyloid: signals and effects.

artículo científico publicado en 2001

Apolipoprotein E and β‐amyloid (1–42) regulation of glycogen synthase kinase‐3β ⬇️

artículo científico publicado el 1 de diciembre de 2003

Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study

artículo científico publicado en 2008

Apolipoprotein E isoform-specific disruption of phosphoinositide hydrolysis: protection by estrogen and glutathione

artículo científico publicado en 2001

Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.

scientific article published on 30 December 2016

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

artículo científico publicado en 2001

Association of Platelet Serotonin Levels in Alzheimer's Disease with Clinical and Cerebrospinal Fluid Markers

artículo científico publicado en 2016

Autoantibodies Toward the Angiotensin 2 Type 1 Receptor: A Novel Autoantibody in Alzheimer's Disease

artículo científico publicado en 2015

Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects

artículo científico publicado en 2009

Can LDL cholesterol be too low? Possible risks of extremely low levels

artículo científico publicado en 2017

Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

artículo científico publicado en 2001

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes

artículo científico publicado en 2006

Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.

artículo científico publicado en 2014

Cholinergic hypofunction impairs memory acquisition possibly through hippocampal Arc and BDNF downregulation

artículo científico publicado en 2010

Chronic airway-induced allergy in mice modifies gene expression in the brain toward insulin resistance and inflammatory responses.

artículo científico publicado en 2013

Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice.

artículo científico publicado en 2012

Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases

scientific article published on 08 March 2019

Current and emerging avenues for Alzheimer's disease drug targets

scientific article published on 29 August 2019

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

artículo científico publicado en 2010

Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease

artículo científico publicado en 2014

Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

artículo científico publicado en 2015

Defeating Alzheimer's disease and other dementias: a priority for European science and society

artículo científico publicado en 2016

Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms

artículo científico publicado en 2012

Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts

scientific article published on 01 June 2001

Estrogen protects against amyloid-β toxicity by estrogen receptor α-mediated inhibition of Daxx translocation.

artículo científico publicado en 2011

Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers

artículo científico publicado en 2018

Ezrin mediates c-Myc actions in prostate cancer cell invasion.

artículo científico publicado en 2009

Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction

artículo científico publicado en 2003

Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs

artículo científico publicado en 2012

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease

artículo científico publicado en 2010

High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.

artículo científico publicado en 2005

Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain

artículo científico publicado en 2009

Insufficient resolution response in the hippocampus of a senescence-accelerated mouse model--SAMP8.

artículo científico publicado en 2014

Insulin deprivation decreases insulin degrading enzyme levels in primary cultured cortical neurons and in the cerebral cortex of rats with streptozotocin-induced diabetes

artículo científico publicado en 2018

Insulin levels are decreased in the cerebrospinal fluid of women with prodomal Alzheimer's disease.

artículo científico publicado en 2010

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.

artículo científico publicado en 2012

Intracellular localization of amyloid-β peptide in SH-SY5Y neuroblastoma cells.

artículo científico publicado en 2013

Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease.

artículo científico publicado en 2005

Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?

artículo científico publicado en 2013

Lack of insulin results in reduced seladin-1 expression in primary cultured neurons and in cerebral cortex of STZ-induced diabetic rats.

artículo científico publicado en 2016

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition

artículo científico publicado en 2019

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation

scientific article published on 15 February 2019

Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells

artículo científico publicado en 2011

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

artículo científico publicado en 2009

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.

artículo científico publicado en 2016

Nicergoline stimulates protein kinase C mediated alpha-secretase processing of the amyloid precursor protein in cultured human neuroblastoma SH-SY5Y cells

artículo científico publicado en 1999

Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?

artículo científico publicado en 2014

Oxysterols and neurodegenerative diseases.

artículo científico publicado en 2009

Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling.

artículo científico publicado en 2009

Parkin-mediated ubiquitination regulates phospholipase C-gamma1.

artículo científico publicado en 2008

Pathways to Alzheimer's disease

artículo científico

Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease

artículo científico publicado en 2016

Plasma cholesterol and risk for late-onset Alzheimer’s disease ⬇️

artículo científico publicado el 1 de abril de 2011

Presenilin dependence of phospholipase C and protein kinase C signaling.

artículo científico publicado en 2007

Presenilin regulates extracellular regulated kinase (Erk) activity by a protein kinase C alpha dependent mechanism

artículo científico publicado en 2008

Presenilin-mediated signal transduction

artículo científico publicado en 2007

Prospective analysis of carotid arterial wall structure in pediatric renal transplants with ambulatory normotension and in treated hypertensive recipients

artículo científico publicado en 2008

Protein kinase C and amyloid precursor protein processing in skin fibroblasts from sporadic and familial Alzheimer's disease cases

artículo científico publicado en 1999

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts

artículo científico publicado en 2018

Regulation of apolipoprotein E secretion in rat primary hippocampal astrocyte cultures

artículo científico publicado en 2001

Resistance training does not have an effect on cognition or related serum biomarkers in nonagenarians: a randomized controlled trial.

artículo científico publicado en 2014

Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism

artículo científico publicado en 2011

Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse

artículo científico publicado en 2014

Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?

artículo científico publicado en 2014

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

artículo científico publicado en 2016

Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons.

artículo científico publicado en 2017

The composition of polypharmacy: A register-based study of Swedes aged 75 years and older.

artículo científico publicado en 2018

The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations

artículo científico publicado en 2002

Thioredoxin-80 protects against amyloid-beta pathology through autophagic-lysosomal pathway regulation

artículo científico publicado en 2019

Thioredoxin‐80 is a product of alpha‐secretase cleavage that inhibits amyloid‐beta aggregation and is decreased in Alzheimer's disease brain ⬇️

artículo científico publicado el 30 de agosto de 2012

Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics

artículo científico publicado en 2012

Toward common mechanisms for risk factors in Alzheimer's syndrome

artículo científico publicado en 2017

Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease

artículo científico publicado en 2011

Vitamin D in relation to cognitive impairment, cerebrospinal fluid biomarkers, and brain volumes

artículo científico publicado en 2014

side-chain-oxidized oxysterols upregulate ACE2 and Mas receptor in rat primary neurons

artículo científico publicado en 2012

Lista de obras de Angel Cedazo-Minguez

24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis

27-Hydroxycholesterol Induces Aberrant Morphology and Synaptic Dysfunction in Hippocampal Neurons

27-Hydroxycholesterol impairs neuronal glucose uptake through an IRAP/GLUT4 system dysregulation.

27-hydroxycholesterol mediates negative effects of dietary cholesterol on cognition in mice

5-HT1B and other related serotonergic proteins are altered in APPswe mutation.

A new metabolomic workflow for early detection of Alzheimer's disease

Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain

Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ Productions.

Alterations in brain leptin signalling in spite of unchanged CSF leptin levels in Alzheimer's disease

Analysis of chiral amino acids in cerebrospinal fluid samples linked to different stages of Alzheimer disease.

Androgen induction of prostate cancer cell invasion is mediated by ezrin.

Anthocyanins protect from complex I inhibition and APPswe mutation through modulation of the mitochondrial fission/fusion pathways

Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities.

Apolipoprotein E and beta A4-amyloid: signals and effects.

Apolipoprotein E and β‐amyloid (1–42) regulation of glycogen synthase kinase‐3β ⬇️

Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study

Apolipoprotein E isoform-specific disruption of phosphoinositide hydrolysis: protection by estrogen and glutathione

Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

Association of Platelet Serotonin Levels in Alzheimer's Disease with Clinical and Cerebrospinal Fluid Markers

Autoantibodies Toward the Angiotensin 2 Type 1 Receptor: A Novel Autoantibody in Alzheimer's Disease

Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects

Can LDL cholesterol be too low? Possible risks of extremely low levels

Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes

Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.

Cholinergic hypofunction impairs memory acquisition possibly through hippocampal Arc and BDNF downregulation

Chronic airway-induced allergy in mice modifies gene expression in the brain toward insulin resistance and inflammatory responses.

Combination of apolipoprotein E4 and high carbohydrate diet reduces hippocampal BDNF and arc levels and impairs memory in young mice.

Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases

Current and emerging avenues for Alzheimer's disease drug targets

DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

Decreased cerebrospinal fluid levels of L-carnitine in non-apolipoprotein E4 carriers at early stages of Alzheimer's disease

Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

Defeating Alzheimer's disease and other dementias: a priority for European science and society

Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms

Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts

Estrogen protects against amyloid-β toxicity by estrogen receptor α-mediated inhibition of Daxx translocation.

Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers

Ezrin mediates c-Myc actions in prostate cancer cell invasion.

Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction

Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs

HPA axis dysregulation associated to apolipoprotein E4 genotype in Alzheimer's disease

High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.

Impaired long term memory consolidation in transgenic mice overexpressing the human soluble form of IL-1ra in the brain

Insufficient resolution response in the hippocampus of a senescence-accelerated mouse model--SAMP8.

Insulin deprivation decreases insulin degrading enzyme levels in primary cultured cortical neurons and in the cerebral cortex of rats with streptozotocin-induced diabetes

Insulin levels are decreased in the cerebrospinal fluid of women with prodomal Alzheimer's disease.

Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system.

Intracellular localization of amyloid-β peptide in SH-SY5Y neuroblastoma cells.

Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease.

Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?

Lack of insulin results in reduced seladin-1 expression in primary cultured neurons and in cerebral cortex of STZ-induced diabetic rats.

Lithium treatment reverses irradiation-induced changes in rodent neural progenitors and rescues cognition

Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation

Macroautophagy-generated increase of lysosomal amyloid β-protein mediates oxidant-induced apoptosis of cultured neuroblastoma cells

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk.

Nicergoline stimulates protein kinase C mediated alpha-secretase processing of the amyloid precursor protein in cultured human neuroblastoma SH-SY5Y cells

Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?

Oxysterols and neurodegenerative diseases.

Parkin deficiency disrupts calcium homeostasis by modulating phospholipase C signalling.

Parkin-mediated ubiquitination regulates phospholipase C-gamma1.

Pathways to Alzheimer's disease

Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease

Plasma cholesterol and risk for late-onset Alzheimer’s disease ⬇️

Presenilin dependence of phospholipase C and protein kinase C signaling.

Presenilin regulates extracellular regulated kinase (Erk) activity by a protein kinase C alpha dependent mechanism

Presenilin-mediated signal transduction

Prospective analysis of carotid arterial wall structure in pediatric renal transplants with ambulatory normotension and in treated hypertensive recipients

Protein kinase C and amyloid precursor protein processing in skin fibroblasts from sporadic and familial Alzheimer's disease cases

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts

Regulation of apolipoprotein E secretion in rat primary hippocampal astrocyte cultures

Resistance training does not have an effect on cognition or related serum biomarkers in nonagenarians: a randomized controlled trial.

Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism

Sildenafil Decreases BACE1 and Cathepsin B Levels and Reduces APP Amyloidogenic Processing in the SAMP8 Mouse

Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?

Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.