Lista de obras - Jeroen E Guikema - Dominio Público Uruguay

A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi.

artículo científico publicado en 2013

A novel chronic lymphocytic leukemia subset expressing mutated IGHV3-7-encoded rheumatoid factor B-cell receptors that are functionally proficient

artículo científico publicado en 2012

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

artículo científico publicado en 2020

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

artículo científico publicado en 2007

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

artículo científico publicado en 2014

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.

artículo científico publicado en 2016

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells

artículo científico publicado en 2011

Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair

artículo científico publicado en 2007

Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.

artículo científico publicado en 2011

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

artículo científico publicado en 2014

Autologous stem cell transplantation in multiple myeloma after VAD and EDAP courses: a high incidence of oligoclonal serum Igs post transplantation

scientific article published on 01 April 2000

B-Lymphoblastic Lymphomas Evolving from Follicular Lymphomas Co-Express Surrogate Light Chains and Mutated Gamma Heavy Chains.

artículo científico publicado en 2016

CD27 is heterogeneously expressed in multiple myeloma: low CD27 expression in patients with high-risk disease

artículo científico publicado en 2003

CD27-triggering on primary plasma cell leukaemia cells has anti-apoptotic effects involving mitogen activated protein kinases.

artículo científico publicado en 2004

Chronic lymphocytic leukemia development is accelerated in mice with deficiency of the pro-apoptotic regulator NOXA.

artículo científico publicado en 2016

Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model.

artículo científico publicado en 2013

Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination.

artículo científico publicado en 2005

Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing

artículo científico publicado en 2017

Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group

artículo científico publicado en 2000

De novo gene mutations in normal human memory B cells

article

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay.

artículo científico publicado en 2017

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

artículo científico publicado en 2017

Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype

artículo científico publicado en 2003

H2AX is not affected in mantle cell lymphoma with 11q23 deletion

artículo científico publicado en 2006

Heterogeneity in the multiple myeloma tumor clone.

artículo científico publicado en 2004

Identification of a novel stereotypic IGHV4-59/IGHJ5-encoded B-cell receptor subset expressed by various B-cell lymphomas with high affinity rheumatoid factor activity.

artículo científico publicado en 2016

In vitro induction of antibody secretion of primary B-cell chronic lymphocytic leukaemia cells

scientific article published on 10 September 2014

MYC in diffuse large B-cell lymphoma: always the bad guy?

scientific article published on 18 June 2015

Mechanism and regulation of class switch recombination

artículo científico publicado en 2008

Mobilized human CD34+ hematopoietic stem cells enhance tumor growth in a nonobese diabetic/severe combined immunodeficient mouse model of human non-Hodgkin's lymphoma

scientific article published on 01 October 2001

Multiple myeloma related cells in patients undergoing autologous peripheral blood stem cell transplantation

artículo científico publicado en 1999

Myeloma clonotypic B cells are hampered in their ability to undergo B-cell differentiation in vitro

artículo científico publicado en 2002

NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity

artículo científico publicado en 2015

Quantitative RT-PCR analysis of activation-induced cytidine deaminase expression in tissue samples from mantle cell lymphoma and B-cell chronic lymphocytic leukemia patients

artículo científico publicado en 2005

Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.

artículo científico publicado en 2008

Stereotypic rheumatoid factors that are frequently expressed in mucosa-associated lymphoid tissue-type lymphomas are rare in the labial salivary glands of patients with Sjögren's syndrome.

artículo científico publicado en 2015

Structure and consequences of IGH switch breakpoints in Burkitt lymphoma.

artículo científico publicado en 2008

The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.

artículo científico publicado en 2017

The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling

artículo científico publicado en 2016

The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors

artículo científico publicado en 2019

The role of Apex2 in class-switch recombination of immunoglobulin genes

article

ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.

artículo científico publicado en 2017

Lista de obras de Jeroen E Guikema

A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi.

A novel chronic lymphocytic leukemia subset expressing mutated IGHV3-7-encoded rheumatoid factor B-cell receptors that are functionally proficient

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins.

Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells

Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair

Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.

Apurinic/apyrimidinic endonuclease 2 regulates the expansion of germinal centers by protecting against activation-induced cytidine deaminase-independent DNA damage in B cells.

Autologous stem cell transplantation in multiple myeloma after VAD and EDAP courses: a high incidence of oligoclonal serum Igs post transplantation

B-Lymphoblastic Lymphomas Evolving from Follicular Lymphomas Co-Express Surrogate Light Chains and Mutated Gamma Heavy Chains.

CD27 is heterogeneously expressed in multiple myeloma: low CD27 expression in patients with high-risk disease

CD27-triggering on primary plasma cell leukaemia cells has anti-apoptotic effects involving mitogen activated protein kinases.

Chronic lymphocytic leukemia development is accelerated in mice with deficiency of the pro-apoptotic regulator NOXA.

Chronic lymphocytic leukemia disease progression is accelerated by APRIL-TACI interaction in the TCL1 transgenic mouse model.

Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination.

Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing

Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group

De novo gene mutations in normal human memory B cells

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay.

Exploiting the pro-apoptotic function of NOXA as a therapeutic modality in cancer.

Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype

H2AX is not affected in mantle cell lymphoma with 11q23 deletion

Heterogeneity in the multiple myeloma tumor clone.

Identification of a novel stereotypic IGHV4-59/IGHJ5-encoded B-cell receptor subset expressed by various B-cell lymphomas with high affinity rheumatoid factor activity.

In vitro induction of antibody secretion of primary B-cell chronic lymphocytic leukaemia cells

MYC in diffuse large B-cell lymphoma: always the bad guy?

Mechanism and regulation of class switch recombination

Mobilized human CD34+ hematopoietic stem cells enhance tumor growth in a nonobese diabetic/severe combined immunodeficient mouse model of human non-Hodgkin's lymphoma

Multiple myeloma related cells in patients undergoing autologous peripheral blood stem cell transplantation

Myeloma clonotypic B cells are hampered in their ability to undergo B-cell differentiation in vitro

NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity

Quantitative RT-PCR analysis of activation-induced cytidine deaminase expression in tissue samples from mantle cell lymphoma and B-cell chronic lymphocytic leukemia patients

Reassessment of the role of Mut S homolog 5 in Ig class switch recombination shows lack of involvement in cis- and trans-switching.

Stereotypic rheumatoid factors that are frequently expressed in mucosa-associated lymphoid tissue-type lymphomas are rare in the labial salivary glands of patients with Sjögren's syndrome.

Structure and consequences of IGH switch breakpoints in Burkitt lymphoma.

The Complex Interplay between DNA Injury and Repair in Enzymatically Induced Mutagenesis and DNA Damage in B Lymphocytes.

The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling

The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors

The role of Apex2 in class-switch recombination of immunoglobulin genes

ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.