Lista de obras - Colin J Suckling - Dominio Público Uruguay

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

artículo científico publicado el 12 de diciembre de 2009

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

scientific article published on 01 June 2000

6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases

artículo científico publicado en 2008

A Powerful Palladium-Catalyzed Multicomponent Process for the Preparation of Oxazolines and Benzoxazoles

artículo científico publicado en 2011

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

scientific article published on 22 September 2009

A divergent synthesis of minor groove binders with tail group variation

artículo científico publicado en 2008

A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11.

artículo científico publicado en 2005

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

scientific article published on 12 March 2009

A prototype solid phase synthesis of pteridines and related heterocyclic compounds

artículo científico publicado en 2003

Amide isosteres in structure-activity studies of antibacterial minor groove binders

artículo científico publicado en 2011

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

artículo científico publicado en 2016

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

artículo científico publicado en 2007

Asymmetric Rhodium-Catalysed Addition of Arylboronic Acids to Acyclic Unsaturated Esters Containing a Basic γ-Amino Group

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives

artículo científico publicado en 2016

Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase

artículo científico publicado en 2014

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

artículo científico publicado en 2015

DNA binding of a short lexitropsin

artículo científico publicado en 2004

DNA sequence recognition by an isopropyl substituted thiazole polyamide

artículo científico publicado en 2004

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

artículo científico publicado en 2013

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

artículo científico publicado en 2004

Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

artículo científico publicado en 2009

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus

artículo científico publicado en 2015

From Multiply Active Natural Product To Candidate Drug? Antibacterial (And Other) Minor Groove Binders for DNA ⬇️

artículo científico publicado el 1 de mayo de 2012

In Silico Footprinting of Ligands Binding to the Minor Groove of DNA

artículo científico publicado en 2005

In situ detection of pterins by SERS.

artículo científico publicado en 2009

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

artículo científico publicado en 2007

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

artículo científico publicado en 2011

Mechanistic Exploration of the Palladium-catalyzed Process for the Synthesis of Benzoxazoles and Benzothiazoles

artículo científico publicado en 2013

Minor groove binders 1998 – 2004

Minor groove binders as anti-infective agents.

artículo científico publicado en 2013

On the Specificity of Reactions Catalysed by the Antibody H11

article

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

artículo científico publicado en 2015

Ranking ligand affinity for the DNA minor groove by experiment and simulation

artículo científico publicado en 2010

Recognition of the DNA minor groove by thiazotropsin analogues

artículo científico publicado en 2014

Selective anti-malarial minor groove binders

artículo científico publicado en 2016

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

artículo científico publicado en 2004

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

artículo científico publicado en 2014

Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening

artículo científico publicado en 2016

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

artículo científico publicado en 2014

Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases

artículo científico publicado en 2010

Syntheses of highly functionalised 6-substituted pteridines

artículo científico publicado en 2003

Synthesis and antimicrobial activity of some netropsin analogues

artículo científico publicado en 2004

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties

artículo científico publicado en 2010

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits

artículo científico publicado en 2015

The amazingly patient tutor: students' interactions with an online carbohydrate chemistry course

The diversity‐oriented synthesis of pteridines—achievements and potential for development ⬇️

artículo científico publicado el 26 de febrero de 2013

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

artículo científico publicado en 2013

Lista de obras de Colin J Suckling

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases

A Powerful Palladium-Catalyzed Multicomponent Process for the Preparation of Oxazolines and Benzoxazoles

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

A divergent synthesis of minor groove binders with tail group variation

A modelling study of a non-concerted hydrolytic cycloaddition reaction by the catalytic antibody H11.

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

A prototype solid phase synthesis of pteridines and related heterocyclic compounds

Amide isosteres in structure-activity studies of antibacterial minor groove binders

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

Asymmetric Rhodium-Catalysed Addition of Arylboronic Acids to Acyclic Unsaturated Esters Containing a Basic γ-Amino Group

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives

Communication between the Zinc and Tetrahydrobiopterin Binding Sites in Nitric Oxide Synthase

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

DNA binding of a short lexitropsin

DNA sequence recognition by an isopropyl substituted thiazole polyamide

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus

From Multiply Active Natural Product To Candidate Drug? Antibacterial (And Other) Minor Groove Binders for DNA ⬇️

In Silico Footprinting of Ligands Binding to the Minor Groove of DNA

In situ detection of pterins by SERS.

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

Mechanistic Exploration of the Palladium-catalyzed Process for the Synthesis of Benzoxazoles and Benzothiazoles

Minor groove binders 1998 – 2004

Minor groove binders as anti-infective agents.

On the Specificity of Reactions Catalysed by the Antibody H11

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

Ranking ligand affinity for the DNA minor groove by experiment and simulation

Recognition of the DNA minor groove by thiazotropsin analogues

Selective anti-malarial minor groove binders

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases

Syntheses of highly functionalised 6-substituted pteridines

Synthesis and antimicrobial activity of some netropsin analogues

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits

The amazingly patient tutor: students' interactions with an online carbohydrate chemistry course

The diversity‐oriented synthesis of pteridines—achievements and potential for development ⬇️

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles