Lista de obras - Abedawn I. Khalaf - Dominio Público Uruguay

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

artículo científico publicado el 12 de diciembre de 2009

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

scientific article published on 01 June 2000

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

scientific article published on 22 September 2009

A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry

artículo científico publicado en 2017

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

scientific article published on 12 March 2009

Amide isosteres in structure-activity studies of antibacterial minor groove binders

artículo científico publicado en 2011

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

artículo científico publicado en 2016

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

artículo científico publicado en 2007

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

artículo científico publicado en 2015

DNA Minor Groove Binders-Inspired by Nature.

artículo científico publicado en 2016

DNA binding of a short lexitropsin

artículo científico publicado en 2004

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B)

artículo científico publicado en 2006

DNA sequence recognition by an isopropyl substituted thiazole polyamide

artículo científico publicado en 2004

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

artículo científico publicado en 2013

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

artículo científico publicado en 2004

Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.

artículo científico publicado en 2017

Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders.

artículo científico publicado en 2017

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

artículo científico publicado en 2007

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

artículo científico publicado en 2019

On the Specificity of Reactions Catalysed by the Antibody H11

article

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

artículo científico publicado en 2015

Ranking ligand affinity for the DNA minor groove by experiment and simulation

artículo científico publicado en 2010

Recognition of the DNA minor groove by thiazotropsin analogues

artículo científico publicado en 2014

Selective anti-malarial minor groove binders

artículo científico publicado en 2016

Selective in vitro anti-cancer activity of non-alkylating minor groove binders

scientific article published on 18 July 2019

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

artículo científico publicado en 2004

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

artículo científico publicado en 2014

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

artículo científico publicado en 2014

Synthesis and antimicrobial activity of some netropsin analogues

artículo científico publicado en 2004

Synthesis of novel DNA binding agents: indole-containing analogues of bis-netropsin

Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis

artículo científico publicado en 2018

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

artículo científico publicado en 2013

Lista de obras de Abedawn I. Khalaf

2,2,2-Trifluoro-N-(isoquinolin-5-ylmethyl)acetamide ⬇️

3-Acetoxycyclohex-4-ene-1,2-dicarboxylic anhydride

A detailed binding free energy study of 2 : 1 ligand–DNA complex formation by experiment and simulation

A method for the analysis of sugars in biological systems using reductive amination in combination with hydrophilic interaction chromatography and high resolution mass spectrometry

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

Amide isosteres in structure-activity studies of antibacterial minor groove binders

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Antimicrobial lexitropsins containing amide, amidine, and alkene linking groups

Crystal structure of N,N-dimethyl-2-[(4-methyl-benz-yl)sulfon-yl]ethanamine

DNA Minor Groove Binders-Inspired by Nature.

DNA binding of a short lexitropsin

DNA sequence recognition by an imidazole-containing isopropyl-substituted thiazole polyamide (thiazotropsin B)

DNA sequence recognition by an isopropyl substituted thiazole polyamide

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity

Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.

Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders.

M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compounds

Novel Minor Groove Binders Cure Animal African Trypanosomiasis in an in Vivo Mouse Model

On the Specificity of Reactions Catalysed by the Antibody H11

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

Ranking ligand affinity for the DNA minor groove by experiment and simulation

Recognition of the DNA minor groove by thiazotropsin analogues

Selective anti-malarial minor groove binders

Selective in vitro anti-cancer activity of non-alkylating minor groove binders

Short lexitropsin that recognizes the DNA minor groove at 5'-ACTAGT-3': understanding the role of isopropyl-thiazole

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1

Synthesis and antimicrobial activity of some netropsin analogues

Synthesis of novel DNA binding agents: indole-containing analogues of bis-netropsin

Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis

Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor groove

Unexpected Dealkylation During Nucleophilic Substitution: Synthesis of 2-N,N-Dialkylamino Benzoxazoles and Benzothiazoles