Lista de obras - Rainer Heuchel - Dominio Público Uruguay

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

artículo científico publicado en 2013

A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.

artículo científico publicado en 2004

A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin

artículo científico publicado en 2008

Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis

artículo científico publicado en 2014

An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta

scientific article published on 01 January 2007

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice

artículo científico publicado en 2010

Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension

artículo científico publicado en 2013

Deletion of exon I of SMAD7 in mice results in altered B cell responses.

artículo científico publicado en 2006

Desmoplasia and chemoresistance in pancreatic cancer

artículo científico publicado en 2014

Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.

artículo científico publicado en 2013

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice

artículo científico publicado en 2008

Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice

artículo científico publicado en 2008

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

artículo científico publicado en 2000

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

artículo científico publicado en 1998

Endoscopic papillectomy and KRAS expression in the treatment of adenoma in the major duodenal papilla.

artículo científico publicado en 2015

Expression and function of the gene encoding the voltage-dependent calcium channel beta3-subunit in the mouse placenta

artículo científico publicado en 2006

Fluorescence labeled microbubbles for multimodal imaging.

artículo científico publicado en 2015

Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

artículo científico publicado en 2011

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

artículo científico publicado en 1997

Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.

artículo científico publicado en 2013

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene

artículo científico publicado en 2011

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy

artículo científico publicado en 2011

Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development

artículo científico publicado en 2017

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

artículo científico publicado en 1999

Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro.

artículo científico publicado en 2007

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

artículo científico publicado en 2006

Platelet-derived growth factor receptor-beta, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma

artículo científico publicado en 2007

Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound.

artículo científico publicado en 2014

Smad7 regulates terminal maturation of chondrocytes in the growth plate

artículo científico publicado en 2013

Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner

artículo científico publicado en 2010

The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains

artículo científico publicado en 2003

The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

artículo científico publicado en 2010

Therapy with Cell Encapsulation for Substitution of Organ Function and Tumor Treatment

Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation

scientific article published on 01 January 2003

Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma

artículo científico publicado en 2015

Lista de obras de Rainer Heuchel

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing

A gain of function mutation in the activation loop of platelet-derived growth factor beta-receptor deregulates its kinase activity.

A gain-of-function mutation in the PDGFR-beta alters the kinetics of injury response in liver and skin

Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis

An activating mutation in the PDGF receptor-beta causes abnormal morphology in the mouse placenta

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice

Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension

Deletion of exon I of SMAD7 in mice results in altered B cell responses.

Desmoplasia and chemoresistance in pancreatic cancer

Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.

Disruption of the Smad7 gene enhances CCI4-dependent liver damage and fibrogenesis in mice

Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice

Efficient TGF-beta induction of the Smad7 gene requires cooperation between AP-1, Sp1, and Smad proteins on the mouse Smad7 promoter

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

Endoscopic papillectomy and KRAS expression in the treatment of adenoma in the major duodenal papilla.

Expression and function of the gene encoding the voltage-dependent calcium channel beta3-subunit in the mouse placenta

Fluorescence labeled microbubbles for multimodal imaging.

Hypoxic pulmonary hypertension in mice with constitutively active platelet-derived growth factor receptor-β.

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.

Multiple phenotypes in adult mice following inactivation of the Coxsackievirus and Adenovirus Receptor (Car) gene

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy

Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development

Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro.

Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation

Platelet-derived growth factor receptor-beta, carrying the activating mutation D849N, accelerates the establishment of B16 melanoma

Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound.

Smad7 regulates terminal maturation of chondrocytes in the growth plate

Smad7 regulates the adult neural stem/progenitor cell pool in a transforming growth factor beta- and bone morphogenetic protein-independent manner

The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains

The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

Therapy with Cell Encapsulation for Substitution of Organ Function and Tumor Treatment

Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation

Variant Profiling of Candidate Genes in Pancreatic Ductal Adenocarcinoma