Lista de obras - John D. Imig - Dominio Público Uruguay

12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels

artículo científico publicado en 2003

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications

artículo científico publicado en 2014

20-HETE or EETs: which arachidonic acid metabolite regulates proximal tubule transporters and contributes to pressure natriuresis?

artículo científico publicado en 2004

20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension

artículo científico publicado en 2010

ACE Inhibition and Bradykinin-Mediated Renal Vascular Responses: EDHF Involvement.

artículo científico publicado en 2004

Adaptations of the renal microcirculation to hypertension.

artículo científico publicado en 2002

Adenosine2A receptors and epoxyeicosatrienoic acids: a recipe for salt and blood pressure regulation

artículo científico publicado en 2009

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

artículo científico publicado en 2009

Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.

artículo científico publicado en 2008

Afferent arteriolar reactivity to angiotensin II is enhanced during the early phase of angiotensin II hypertension.

artículo científico publicado en 2000

Age-related alterations in NOS and oxidative stress in mesenteric arteries from male and female rats

artículo científico publicado en 2004

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

artículo científico publicado en 2001

Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor

artículo científico publicado en 2002

Angiotensin II hypertension is attenuated in interleukin-6 knockout mice

artículo científico publicado en 2005

Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.

artículo científico publicado en 2013

Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.

artículo científico publicado en 2013

Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.

artículo científico publicado en 2013

Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.

artículo científico publicado en 2007

Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat

scientific article published on 01 August 2014

Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats

artículo científico publicado en 2014

Calcium Mobilization Contributes to Pressure-Mediated Afferent Arteriolar Vasoconstriction ⬇️

artículo científico publicado el 1 de enero de 1998

Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells

artículo científico publicado en 2005

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.

artículo científico publicado en 2012

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

artículo científico publicado en 2006

Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension

artículo científico publicado en 2015

Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.

artículo científico publicado en 2007

Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.

artículo científico publicado en 2010

Correction to 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications

scholarly article published in Journal of Medicinal Chemistry

Cytochrome P450 eicosanoids and cerebral vascular function ⬇️

artículo científico publicado el 1 de marzo de 2011

Cytochrome P450 epoxygenases provide a novel mechanism for penile erection

artículo científico publicado en 2006

Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats

artículo científico publicado en 2004

Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.

artículo científico publicado en 2002

Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.

artículo científico publicado en 2011

Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions

artículo científico publicado en 2010

Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.

artículo científico publicado en 2014

Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension

artículo científico publicado en 2003

ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin

artículo científico publicado en 2005

Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat

artículo científico publicado en 2000

Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats

artículo científico publicado en 2007

Eicosanoids and renal damage in cardiometabolic syndrome.

artículo científico publicado en 2008

Eicosanoids and renal vascular function in diseases.

artículo científico publicado en 2006

Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats

artículo científico publicado en 2015

Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation

artículo científico publicado en 2004

Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet

artículo científico publicado en 2007

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

artículo científico publicado en 2010

Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes

artículo científico publicado en 2005

Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid

artículo científico publicado en 2001

Epigenetic Soluble Epoxide Hydrolase Regulation Causes Endothelial Dysfunction

artículo científico publicado en 2018

Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases

artículo científico publicado en 2005

Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury

artículo científico publicado en 2014

Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.

artículo científico publicado en 2014

Epoxyeicosatrienoic acids, 20-hydroxyeicosatetraenoic acid, and renal microvascular function

artículo científico publicado en 2013

Epoxyeicosatrienoic acids, hypertension, and kidney injury

artículo científico publicado en 2015

Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin

artículo científico publicado en 2001

Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.

artículo científico publicado en 2013

Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.

artículo científico publicado en 2011

Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.

artículo científico publicado en 2014

IL6 suppression provides renal protection independent of blood pressure in a murine model of salt-sensitive hypertension

scientific article published on 15 June 2007

Immune and inflammatory role in renal disease.

artículo científico publicado en 2013

Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension

artículo científico publicado en 2005

Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats

scientific article published on 28 March 2006

Increased blood pressure in mice lacking cytochrome P450 2J5

scientific journal article

Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.

artículo científico publicado en 2009

Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE

artículo científico publicado en 2006

Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.

artículo científico publicado en 2012

Inhibition of soluble epoxide hydrolase improves the impaired pressure–natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats ⬇️

artículo científico publicado el 1 de agosto de 2011

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats

artículo científico publicado en 2014

Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation.

artículo científico publicado en 2014

Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.

artículo científico publicado en 2010

L-type calcium channels in the renal microcirculatory response to endothelin

artículo científico publicado en 2004

Normalization of the ovarian cancer microenvironment by SPARC.

artículo científico publicado en 2007

Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats

artículo científico publicado en 2007

Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.

artículo científico publicado en 2013

Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension.

artículo científico publicado en 2009

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

artículo científico publicado en 2010

Obesity, insulin resistance, and renal function.

artículo científico publicado en 2007

Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.

artículo científico publicado en 2013

Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.

artículo científico publicado en 2015

P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid

artículo científico publicado en 2004

PPAR-alpha activator fenofibrate increases renal CYP-derived eicosanoid synthesis and improves endothelial dilator function in obese Zucker rats

artículo científico publicado en 2006

Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade

scientific journal article

Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy.

artículo científico publicado en 2014

Postglomerular vasoconstriction to angiotensin II and norepinephrine depends on intracellular calcium release

artículo científico publicado en 2000

Protein phosphatase 2A and Ca2+-activated K+ channels contribute to 11,12-epoxyeicosatrienoic acid analog mediated mesenteric arterial relaxation

artículo científico publicado en 2006

Renal AT1 receptor protein expression during the early stage of diabetes mellitus.

artículo científico publicado en 2002

Renal autoregulation in P2X1 knockout mice.

artículo científico publicado en 2004

Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension

artículo científico publicado en 2011

Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor

artículo científico publicado en 1998

Reply to "Letter to the editor: 'Concern regarding quantification of urinary nephrin by commercially available ELISA'"

scientific article published on 01 August 2015

Rofecoxib decreases renal injury in obese Zucker rats

artículo científico publicado en 2004

Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats

artículo científico publicado en 2011

Roles of the cytochrome P450 arachidonic acid monooxygenases in the control of systemic blood pressure and experimental hypertension.

artículo científico publicado en 2007

Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases

scientific article published on 04 August 2003

Simvastatin and tempol protect against endothelial dysfunction and renal injury in a model of obesity and hypertension.

artículo científico publicado en 2009

Soluble epoxide hydrolase contamination of specific catalase preparations inhibits epoxyeicosatrienoic acid vasodilation of rat renal arterioles.

artículo científico publicado en 2011

Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance ⬇️

artículo científico publicado el 12 de mayo de 2011

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

scientific journal article

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.

artículo científico publicado en 2009

Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels

artículo científico publicado en 2006

TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats

artículo científico publicado en 2007

Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome.

artículo científico publicado en 2011

The Bradykinin B2 receptor is required for full expression of renal COX-2 and renin.

artículo científico publicado en 2003

The Cyp2c44 epoxygenase regulates epithelial sodium channel activity and the blood pressure responses to increased dietary salt.

scientific article published on 24 December 2013

The Roles of Intrarenal 20-Hydroxyeicosatetraenoic and Epoxyeicosatrienoic Acids in the Regulation of Renal Function in Hypertensive Ren-2 Transgenic Rats

artículo científico publicado en 2007

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet

artículo científico publicado en 2013

Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension

artículo científico publicado en 2006

Tumour necrosis factor-α contributes to improved cardiac ischaemic tolerance in rats adapted to chronic continuous hypoxia

artículo científico publicado en 2015

Lista de obras de John D. Imig

12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels

14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications

20-HETE or EETs: which arachidonic acid metabolite regulates proximal tubule transporters and contributes to pressure natriuresis?

20-hydroxyeicosatetraenoic acid and angiotensin: a positive feedback system to cause hypertension

ACE Inhibition and Bradykinin-Mediated Renal Vascular Responses: EDHF Involvement.

Adaptations of the renal microcirculation to hypertension.

Adenosine2A receptors and epoxyeicosatrienoic acids: a recipe for salt and blood pressure regulation

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.

Afferent arteriolar reactivity to angiotensin II is enhanced during the early phase of angiotensin II hypertension.

Age-related alterations in NOS and oxidative stress in mesenteric arteries from male and female rats

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor

Angiotensin II hypertension is attenuated in interleukin-6 knockout mice

Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension.

Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.

Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME.

Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.

Azilsartan decreases renal and cardiovascular injury in the spontaneously hypertensive obese rat

Azilsartan improves glycemic status and reduces kidney damage in zucker diabetic fatty rats

Calcium Mobilization Contributes to Pressure-Mediated Afferent Arteriolar Vasoconstriction ⬇️

Calcium and chloride channel activation by angiotensin II-AT1 receptors in preglomerular vascular smooth muscle cells

Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.

Cardiovascular therapeutic aspects of soluble epoxide hydrolase inhibitors.

Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension

Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.

Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats.

Correction to 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) Surrogates: Carboxylate Modifications

Cytochrome P450 eicosanoids and cerebral vascular function ⬇️

Cytochrome P450 epoxygenases provide a novel mechanism for penile erection

Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats

Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension.

Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.

Development of epoxyeicosatrienoic acid analogs with in vivo anti-hypertensive actions

Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats.

Downregulation of renal CYP-derived eicosanoid synthesis in rats with diet-induced hypertension

ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin

Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat

Effects of chronic cytochrome P-450 inhibition on the course of hypertension and end-organ damage in Ren-2 transgenic rats

Eicosanoids and renal damage in cardiometabolic syndrome.

Eicosanoids and renal vascular function in diseases.

Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats

Elevated arterial pressure impairs autoregulation independently of AT(1) receptor activation

Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet

Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.

Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes

Enhanced renal microvascular reactivity to angiotensin II in hypertension is ameliorated by the sulfonimide analog of 11,12-epoxyeicosatrienoic acid

Epigenetic Soluble Epoxide Hydrolase Regulation Causes Endothelial Dysfunction

Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases

Epoxyeicosatrienoic acid analog attenuates angiotensin II hypertension and kidney injury

Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition.

Epoxyeicosatrienoic acids, 20-hydroxyeicosatetraenoic acid, and renal microvascular function

Epoxyeicosatrienoic acids, hypertension, and kidney injury

Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin

Fructose stimulates Na/H exchange activity and sensitizes the proximal tubule to angiotensin II.

Glomerular expression of kidney injury molecule-1 and podocytopenia in diabetic glomerulopathy.

Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy.

IL6 suppression provides renal protection independent of blood pressure in a murine model of salt-sensitive hypertension

Immune and inflammatory role in renal disease.

Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension

Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats

Increased blood pressure in mice lacking cytochrome P450 2J5

Increased renal proximal convoluted tubule transport contributes to hypertension in Cyp4a14 knockout mice.

Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE

Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension.

Inhibition of soluble epoxide hydrolase improves the impaired pressure–natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats ⬇️

Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats

Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation.

Intrarenal cytochrome P-450 metabolites of arachidonic acid in the regulation of the nonclipped kidney function in two-kidney, one-clip Goldblatt hypertensive rats.

L-type calcium channels in the renal microcirculatory response to endothelin

Normalization of the ovarian cancer microenvironment by SPARC.

Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats

Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.

Obesity induced renal oxidative stress contributes to renal injury in salt-sensitive hypertension.

Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

Obesity, insulin resistance, and renal function.

Orally active epoxyeicosatrienoic acid analog attenuates kidney injury in hypertensive Dahl salt-sensitive rat.

Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats.

P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid