Lista de obras - David M Sansom - Dominio Público Uruguay

1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept

artículo científico publicado en 2015

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

artículo científico publicado en 2009

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

artículo científico publicado en 2016

A role for RANTES in T lymphocyte proliferation

artículo científico publicado en 1996

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

artículo científico publicado en 2015

A transendocytosis perspective on the CD28/CTLA-4 pathway

artículo científico

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3

artículo científico publicado en 2008

Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95

artículo científico publicado en 1998

Activation of phosphatidylinositol 3-kinase following Fas engagement is not required for Fas-mediated apoptosis in Jurkat T cells

artículo científico publicado en 1997

Activation of the PI3K effector protein kinase B following ligation of CD28 or Fas

artículo científico publicado en 1997

Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-trisphosphate formation in T lymphocytes

artículo científico publicado en 1995

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

artículo científico publicado en 2014

Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses

artículo científico publicado en 2012

B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro.

artículo científico publicado en 1993

B7/CD28 but not LFA-3/CD2 interactions can provide 'third-party' co-stimulation for human T-cell activation

artículo científico publicado en 1993

CD28 costimulation: Walking the immunological tightrope ⬇️

artículo científico publicado el 1 de enero de 2013

CD28, CTLA-4 and their ligands: who does what and to whom?

artículo científico publicado en 2000

CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells

artículo científico publicado en 2004

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement

artículo científico publicado en 2014

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

artículo científico publicado en 2019

CTLA-4: a moving target in immunotherapy.

artículo científico publicado en 2017

CTLA4 gene polymorphism and autoimmunity

artículo científico publicado en 2005

Characterization of CTLA4 Trafficking and Implications for Its Function

article published in 2018

Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity.

artículo científico publicado en 1993

Comparison of the intracellular trafficking itinerary of ctla-4 orthologues

artículo científico publicado en 2013

Confusing signals: recent progress in CTLA-4 biology

artículo científico

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation

artículo científico publicado en 2012

Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

artículo científico publicado en 2017

Costimulation of human CD4+ T lymphocytes with B7 and lymphocyte function-associated antigen-3 results in distinct cell activation profiles.

artículo científico publicado en 1994

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

artículo científico publicado en 2009

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

artículo científico publicado en 2012

Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human cd4+ tcr2+ cultured T cell clones

artículo científico publicado en 1996

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint

artículo científico publicado en 2017

Differential expression of the costimulatory molecules B7.1 (CD80) and B7.2 (CD86) in rheumatoid synovial tissue

artículo científico publicado en 1996

Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis

artículo científico publicado en 1998

Effects of antigen presentation on superantigen-induced apoptosis mediated by Fas/Fas ligand interactions in human T cells

artículo científico publicado en 1996

Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.

artículo científico publicado en 1997

Exocytosis of CTLA-4 is dependent on phospholipase D and ADP ribosylation factor-1 and stimulated during activation of regulatory T cells

artículo científico publicado en 2005

Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue ⬇️

artículo científico publicado el 1 de marzo de 2011

Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: Effects of glucocorticoids

artículo científico publicado en 1995

Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease

artículo científico publicado en 2007

Follicular helper T cell signature in type 1 diabetes

artículo científico publicado en 2014

Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals

artículo científico publicado en 2017

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

artículo científico publicado en 2020

HLA DQ POLYMORPHISM IN RHEUMATOID ARTHRITIS

scientific article published on 01 January 1988

HLA DQα and DQβ restriction fragment length polymorphisms associated with Felty's syndrome and DR4-positive rheumatoid arthritis

scientific article published on 01 August 1987

HLA-DO-related restriction fragment length polymorphisms in rheumatoid arthritis: evidence for a link with disease expression

scientific article published on 01 October 1989

HLA-DP in rheumatoid arthritis

artículo científico publicado en 1988

Hematopoietic stem cell transplantation for CTLA4 deficiency

article

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

scientific article published on 15 July 2019

Human gamma delta T cells are resistant to induction of anergy but not to induction of cell death in vitro

artículo científico publicado en 1995

Human naive and memory T-helper cells display distinct adhesion properties to ICAM-1, LFA-3 and B7 molecules

artículo científico publicado en 1993

Human vascular endothelial cells process and present autoantigen to human T cell lines.

artículo científico publicado en 1995

IL-2-independent activation and proliferation in human T cells induced by CD28.

artículo científico publicado en 1999

IMMUNOLOGY. Moving CTLA-4 from the trash to recycling.

artículo científico publicado en 2015

Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition

artículo científico publicado en 2004

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

artículo científico publicado en 2017

Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.

artículo científico publicado en 2017

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

artículo científico publicado en 1995

Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells

artículo científico publicado en 2002

Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86.

artículo científico publicado en 2006

Lack of activation induced cell death in human T blasts despite CD95L up-regulation: protection from apoptosis by MEK signalling

artículo científico publicado en 1999

Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

artículo científico publicado en 1997

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis

artículo científico publicado en 2014

Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

artículo científico publicado en 2002

Measuring CTLA-4-Dependent Suppressive Function in Regulatory T Cells

scientific article published on 01 January 2019

Monocyte-regulated IFN-gamma production in human T cells involves CD2 signaling

artículo científico publicado en 1993

Mutually exclusive binding of peptide and invariant chain to major histocompatibility complex class II antigens.

artículo científico publicado en 1994

New vector for transfer of yeast artificial chromosomes to mammalian cells

artículo científico publicado en 1993

Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset.

artículo científico publicado en 2004

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects

artículo científico publicado en 2018

Phorbol esters modulate the coupling of the T cell costimulatory molecule CD28 to phosphatidylinositol 3-kinase

artículo científico publicado en 1997

Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80

artículo científico publicado en 1998

Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

scientific article published on 02 October 2019

Regulation of CTLA-4 recycling by LRBA and Rab11

artículo científico publicado en 2021

Regulatory T cells and COPD

artículo científico publicado en 2013

Requirements for Stimulation or Anergy Induction in Alloreactive Human T Cell Clones ⬇️

artículo científico publicado el 1 de octubre de 1994

Restriction fragment length polymorphism in Felty's syndrome

artículo científico publicado en 1986

Strong primary selection for the Dw4 subtype of DR4 accounts for the HLA-DQw7 association with Felty's syndrome

artículo científico publicado en 1991

Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity

artículo científico publicado en 2018

Superantigen activation of CD4+ and CD8+T cells from HIV-infected subjects: role of costimulatory molecules and antigen-presenting cells (APC)

artículo científico publicado en 1998

The LFA-3 adhesion pathway is differently utilized by superantigen-activated human CD4+ T-cell subsets

artículo científico publicado en 1992

The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses ⬇️

artículo científico publicado el 25 de noviembre de 2011

The human ICAM2 gene maps to 17q23–25 ⬇️

artículo científico publicado el 1 de octubre de 1991

The origin of HLA-DR“Br”: Exon 2 nucleotide sequence implicates possible gene conversion of DR1 by DR4-Dw10, DR5, or DRw6-Dw18

article

The phosphoinositide 3-kinase inhibitor wortmannin inhibits CD28-mediated T cell co-stimulation

artículo científico publicado en 1995

The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

artículo científico publicado en 2006

The role of endogenous peptides in the direct pathway of alloreactivity to human MHC class II molecules expressed on CHO cells.

artículo científico publicado en 1996

Thymus transplantation for complete DiGeorge syndrome: European experience.

artículo científico publicado en 2017

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

artículo científico publicado en 2011

Understanding the CD28/CTLA-4 (CD152) pathway and its implications for costimulatory blockade

artículo científico publicado en 2014

Vedolizumab as a successful treatment of CTLA-4-associated autoimmune enterocolitis

artículo científico publicado en 2016

Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function

artículo científico publicado en 2015

Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) ⬇️

artículo científico publicado en 2015

What's the difference between CD80 and CD86?

artículo científico publicado en 2003

Lista de obras de David M Sansom

1,25(OH)2D3 Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept

1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.

A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

A role for RANTES in T lymphocyte proliferation

A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells

A transendocytosis perspective on the CD28/CTLA-4 pathway

Acquisition of suppressive function by activated human CD4+ CD25- T cells is associated with the expression of CTLA-4 not FoxP3

Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95

Activation of phosphatidylinositol 3-kinase following Fas engagement is not required for Fas-mediated apoptosis in Jurkat T cells

Activation of the PI3K effector protein kinase B following ligation of CD28 or Fas

Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-trisphosphate formation in T lymphocytes

Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses

B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro.

B7/CD28 but not LFA-3/CD2 interactions can provide 'third-party' co-stimulation for human T-cell activation

CD28 costimulation: Walking the immunological tightrope ⬇️

CD28, CTLA-4 and their ligands: who does what and to whom?

CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement

CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells

CTLA-4: a moving target in immunotherapy.

CTLA4 gene polymorphism and autoimmunity

Characterization of CTLA4 Trafficking and Implications for Its Function

Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity.

Comparison of the intracellular trafficking itinerary of ctla-4 orthologues

Confusing signals: recent progress in CTLA-4 biology

Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation

Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding

Costimulation of human CD4+ T lymphocytes with B7 and lymphocyte function-associated antigen-3 results in distinct cell activation profiles.

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human cd4+ tcr2+ cultured T cell clones

Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint

Differential expression of the costimulatory molecules B7.1 (CD80) and B7.2 (CD86) in rheumatoid synovial tissue

Down-regulation of CD28 via Fas (CD95): influence of CD28 on T-cell apoptosis

Effects of antigen presentation on superantigen-induced apoptosis mediated by Fas/Fas ligand interactions in human T cells

Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.

Exocytosis of CTLA-4 is dependent on phospholipase D and ADP ribosylation factor-1 and stimulated during activation of regulatory T cells

Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue ⬇️

Expression and secretion of parathyroid hormone-related protein by human bone-derived cells in vitro: Effects of glucocorticoids

Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease

Follicular helper T cell signature in type 1 diabetes

Genetic variation at the CD28 locus and its impact on expansion of pro-inflammatory CD28 negative T cells in healthy individuals

Genomic profiling of T-cell activation suggests increased sensitivity of memory T cells to CD28 costimulation

HLA DQ POLYMORPHISM IN RHEUMATOID ARTHRITIS

HLA DQα and DQβ restriction fragment length polymorphisms associated with Felty's syndrome and DR4-positive rheumatoid arthritis

HLA-DO-related restriction fragment length polymorphisms in rheumatoid arthritis: evidence for a link with disease expression

HLA-DP in rheumatoid arthritis

Hematopoietic stem cell transplantation for CTLA4 deficiency

Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

Human gamma delta T cells are resistant to induction of anergy but not to induction of cell death in vitro

Human naive and memory T-helper cells display distinct adhesion properties to ICAM-1, LFA-3 and B7 molecules

Human vascular endothelial cells process and present autoantigen to human T cell lines.

IL-2-independent activation and proliferation in human T cells induced by CD28.

IMMUNOLOGY. Moving CTLA-4 from the trash to recycling.

Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells

Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86.

Lack of activation induced cell death in human T blasts despite CD95L up-regulation: protection from apoptosis by MEK signalling

Lack of costimulation by both sphingomyelinase and C2 ceramide in resting human T cells

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis

Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

Measuring CTLA-4-Dependent Suppressive Function in Regulatory T Cells

Monocyte-regulated IFN-gamma production in human T cells involves CD2 signaling

Mutually exclusive binding of peptide and invariant chain to major histocompatibility complex class II antigens.

New vector for transfer of yeast artificial chromosomes to mammalian cells

Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset.

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects

Phorbol esters modulate the coupling of the T cell costimulatory molecule CD28 to phosphatidylinositol 3-kinase

Positive and negative regulation of human T cell activation mediated by the CTLA-4/CD28 ligand CD80

Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

Regulation of CTLA-4 recycling by LRBA and Rab11

Regulatory T cells and COPD

Requirements for Stimulation or Anergy Induction in Alloreactive Human T Cell Clones ⬇️

Restriction fragment length polymorphism in Felty's syndrome