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Lista de obras de Joaquim Roca

A GyrB-GyrA fusion protein expressed in yeast cells is able to remove DNA supercoils but cannot substitute eukaryotic topoisomerase II.

artículo científico publicado en 2002

Asymmetric removal of supercoils suggests how topoisomerase II simplifies DNA topology

scientific article published on 01 January 2004

Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils

artículo científico publicado en 2014

Cloning, functional analysis and post-transcriptional regulation of a type II DNA topoisomerase from Leishmania infantum. A new potential target for anti-parasite drugs.

artículo científico publicado en 2003

Condensin minimizes topoisomerase II-mediated entanglements of DNA in vivo

artículo científico publicado en 2020

DNA Topology and Global Architecture of Point Centromeres

artículo científico publicado en 2015

DNA knots occur in intracellular chromatin.

artículo científico publicado en 2017

DNA knots reveal a chiral organization of DNA in phage capsids

artículo científico publicado en 2005

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

artículo científico publicado en 1994

Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach

artículo científico publicado en 2021

Electrophoretic Analysis of the DNA Supercoiling Activity of DNA Gyrase

artículo científico publicado en 2018

Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility

artículo científico publicado en 2009

Failure to relax negative supercoiling of DNA is a primary cause of mitotic hyper-recombination in topoisomerase-deficient yeast cells

artículo científico publicado en 2002

Fractal dimension and localization of DNA knots

scientific article published on 29 January 2007

Genome urbanization: clusters of topologically co-regulated genes delineate functional compartments in the genome of Saccharomyces cerevisiae

artículo científico publicado en 2017

Human gut metatranscriptome changes induced by a fermented milk product are associated with improved tolerance to a flatulogenic diet

artículo científico publicado en 2022

In silico, in vitro and in vivo imageries of type II topoisomerases: Comment on "Disentangling DNA molecules" by Alexander Vologodskii

artículo científico publicado en 2016

Intracellular nucleosomes constrain a DNA linking number difference of -1.26 that reconciles the Lk paradox

scientific article published in Nature Communications

Positional dependence of transcriptional inhibition by DNA torsional stress in yeast chromosomes

artículo científico publicado en 2010

Production of highly knotted DNA by means of cosmid circularization inside phage capsids

artículo científico publicado en 2007

Quantitative disclosure of DNA knot chirality by high-resolution 2D-gel electrophoresis

artículo científico publicado en 2019

Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach

artículo científico publicado en 2006

Structure and Chromosomal Organization of Yeast Genes Regulated by Topoisomerase II.

artículo científico publicado en 2018

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

scientific article published on 01 November 1992

The mechanisms of DNA topoisomerases

artículo científico publicado en 1995

The path of the DNA along the dimer interface of topoisomerase II.

artículo científico publicado en 2004

The torsional state of DNA within the chromosome

artículo científico publicado el 13 de mayo de 2011

Topoisomerase II is required for the production of long Pol II gene transcripts in yeast

artículo científico publicado en 2012

Topoisomerase II minimizes DNA entanglements by proofreading DNA topology after DNA strand passage

artículo científico publicado en 2013

Topoisomerase II regulates yeast genes with singular chromatin architectures

artículo científico publicado en 2013

Topoisomerase II, not topoisomerase I, is the proficient relaxase of nucleosomal DNA.

artículo científico publicado en 2006

Topoisomerase II: a fitted mechanism for the chromatin landscape.

artículo científico publicado en 2008

Transcriptional inhibition by DNA torsional stress.

artículo científico publicado en 2011

Transcriptional supercoiling boosts topoisomerase II-mediated knotting of intracellular DNA

scientific article published on 01 July 2019