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Lista de obras de Anna Karlsson

1,2,3-Triazole-[2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D- ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"-oxathiole 2",2"-dioxide) (TSAO) analogues: synthesis and anti-HIV-1 activity

artículo científico publicado en 1994

2 cloning and expression of mouse deoxycytidine kinase. Pure recombinant mouse and human enzymes show differences in substrate specificity

artículo científico publicado en 1994

2',3'-Dideoxycytidine phosphorylation by recombinant mouse and human deoxycytidine kinase

scientific article published on 01 January 1994

2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase

artículo científico publicado en 2001

3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase

artículo científico publicado en 2010

5-Fluoro-2'-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells

artículo científico publicado en 2004

5‘-Phosphoramidates and 5‘-Diphosphates of 2‘-O-Allyl-β-d-arabinofuranosyl- uracil, -cytosine, and -adenine: Inhibition of Ribonucleotide Reductase

artículo científico publicado en 1999

A monocyte-specific peptide from herpes simplex virus type 2 glycoprotein G activates the NADPH-oxidase but not chemotaxis through a G-protein-coupled receptor distinct from the members of the formyl peptide receptor family

artículo científico publicado en 2007

A proinflammatory peptide from herpes simplex virus type 2 glycoprotein G affects neutrophil, monocyte, and NK cell functions

artículo científico publicado en 2005

A prospective study of 115 initially asymptomatic HIV infected gay men in Stockholm, Sweden

artículo científico publicado en 1991

A simple skin blister technique for the study of in vivo transmigration of human leukocytes

artículo científico

Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells

artículo científico publicado en 2007

Activation of human neutrophils by mycobacterial phenolic glycolipids

artículo científico publicado en 1999

Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1.

artículo científico publicado en 2002

Active site mutants of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

artículo científico publicado en 2003

Activity of various thiocarboxanilide derivatives against wild-type and several mutant human immunodeficiency virus type 1 strains.

artículo científico publicado en 1995

Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA.

artículo científico publicado en 2009

Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

artículo científico publicado en 2002

Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface

artículo científico

Alterations of mitochondrial DNA in CEM cells selected for resistance toward ddC toxicity

artículo científico publicado en 2006

Altered deoxyribonucleotide pools in T-lymphoblastoid cells expressing the multisubstrate nucleoside kinase of Drosophila melanogaster

artículo científico publicado en 2005

An eleven year follow-up of delayed-type hypersensitivity testing for the identification of HIV-1 infected patients at increased risk of developing AIDS

artículo científico publicado en 1996

Assembly and activation of the neutrophil NADPH oxidase in granule membranes

artículo científico publicado en 2002

Biological phenotypes of HIV-1 in pathogenesis and transmission

artículo científico publicado en 1994

Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea

artículo científico publicado en 2001

Bystander effects of nucleoside analogs phosphorylated in the cytosol or mitochondria

artículo científico publicado en 2001

CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor

artículo científico publicado en 2014

Capacitative Ca2+ influx and activation of the neutrophil respiratory burst. Different regulation of plasma membrane- and granule-localized NADPH-oxidase.

artículo científico publicado en 2002

Certain human Gp120-HIV antibodies react with anti-CD4 antibodies

scientific article published on 01 January 1988

Challenging the opinion that SAPHO syndrome is associated with low intracellular ROS production in neutrophils

artículo científico publicado en 2015

Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

artículo científico publicado en 2006

Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events

artículo científico publicado en 2007

Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1

artículo científico publicado en 1997

ChemInform Abstract: Design, Synthesis and Enzymatic Activity of Highly Selective Human Mitochondrial Thymidine Kinase Inhibitors

Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster

artículo científico publicado en 1999

Cloning and expression of human deoxyguanosine kinase cDNA

artículo científico publicado en 1996

Cloning of mouse mitochondrial thymidine kinase 2 cDNA

scientific journal article

Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2

artículo científico publicado en 1997

Collection of in vivo transmigrated neutrophils from human skin

artículo científico

Comparison of sample preparation methods for the high-performance liquid chromatographic analysis of cell culture extracts for triphosphate ribonucleosides and deoxyribonucleosides.

artículo científico publicado en 1987

Concomitant combination therapy for HIV infection preferable over sequential therapy with 3TC and non-nucleoside reverse transcriptase inhibitors

artículo científico publicado en 1996

Conserved gene structure and transcription factor sites in the human and mouse deoxycytidine kinase genes

artículo científico publicado en 2000

Cord blood neutrophils display a galectin-3 responsive phenotype accentuated by vaginal delivery

artículo científico publicado en 2013

Coupling between Catalysis and Oligomeric Structure in Nucleoside Diphosphate Kinase

artículo científico publicado en 1998

Cultured rat and purified human Pneumocystis carinii stimulate intra- but not extracellular free radical production in human neutrophils

artículo científico publicado en 1998

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

artículo científico publicado en 2004

Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy

artículo científico publicado en 2003

Decreased thymidine kinase levels in peripheral blood cells from HIV-seropositive individuals: implications for zidovudine metabolism

artículo científico publicado en 1995

Depletion of mitochondrial DNA by down-regulation of deoxyguanosine kinase expression in non-proliferating HeLa cells

artículo científico publicado en 2007

Desensitization of formyl peptide receptors is abolished in calcium ionophore-primed neutrophils: an association of the ligand-receptor complex to the cytoskeleton is not required for a rapid termination of the NADPH-oxidase response

scientific article published on 01 March 1998

Desensitization of the fMLP-induced NADPH-oxidase response in human neutrophils is lacking in okadaic acid-treated cells

scientific article published on 01 June 1997

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides

artículo científico publicado en 2011

Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.

artículo científico publicado en 2001

Detection of glycoprotein receptors on blotting membranes by binding of live bacteria and amplification by growth

artículo científico publicado en 1995

Differences in kinetic properties of pure recombinant human and mouse deoxycytidine kinase

artículo científico publicado en 1995

Different glycosphingolipid composition in human neutrophil subcellular compartments

artículo científico publicado en 2001

Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: effect on the production of reactive oxygen species during phagocytosis.

artículo científico publicado en 1995

Differential incorporation of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosylguanine into nuclear and mitochondrial DNA.

artículo científico publicado en 2000

Differential intracellular compartmentalization of herpetic thymidine kinases (TKs) in TK gene-transfected tumor cells: molecular characterization of the nuclear localization signal of herpes simplex virus type 1 TK.

artículo científico publicado en 1998

Divergent effects on phagocytosis by macrophage-derived oxygen radicals

artículo científico publicado en 2009

Dual effect of interleukin 4 on HIV-1 expression: Implications for viral phenotypic switch and disease progression ⬇️

artículo científico publicado el 21 de julio de 1998

Dual mechanisms of 9-beta-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells

artículo científico publicado en 2001

Effects of 9-beta-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells

artículo científico publicado en 2003

Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis

artículo científico publicado en 1993

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

artículo científico publicado en 2017

Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors

artículo científico publicado en 2013

Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation

artículo científico publicado en 2006

Enhanced cytotoxicity of nucleoside analogs by overexpression of mitochondrial deoxyguanosine kinase in cancer cell lines

artículo científico publicado en 1998

Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants

artículo científico publicado en 2006

Escherichia coli-induced activation of neutrophil NADPH-oxidase: lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites

artículo científico publicado en 1995

Evidence of an intact N-terminal translocation sequence of human mitochondrial adenylate kinase 4

artículo científico publicado en 2010

Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV.

artículo científico publicado en 2001

From uncertainty to gradually managing and awaiting recovery of a periodic condition- a qualitative study of parents´ experiences of PFAPA syndrome

Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils ⬇️

artículo científico publicado el 1 de mayo de 1998

Galectin-3 enhances monocyte-derived macrophage efferocytosis of apoptotic granulocytes in asthma

Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils

artículo científico publicado en 2008

Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function

artículo científico publicado en 2018

Galectins as inflammatory mediators

artículo científico publicado en 2004

Gene expression deregulation in postnatal skeletal muscle of TK2 deficient mice reveals a lower pool of proliferating myogenic progenitor cells

artículo científico publicado en 2013

Group Specific Component and Susceptibility to HIV Infection and Progression to AIDS ⬇️

artículo científico publicado el 1 de enero de 1988

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

artículo científico publicado en 1993

Hematopoiesis in the thymidine kinase 2 deficient mouse model of mitochondrial DNA depletion syndrome

artículo científico publicado en 2010

Highly favorable antiviral activity and resistance profile of the novel thiocarboxanilide pentenyloxy ether derivatives UC-781 and UC-82 as inhibitors of human immunodeficiency virus type 1 replication

artículo científico publicado en 1996

Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses

artículo científico publicado en 2011

Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria

artículo científico publicado en 2008

Human deoxycytidine kinase is located in the cell nucleus

artículo científico publicado en 1997

Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants

artículo científico publicado en 1994

Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.

artículo científico publicado en 1993

Human immunodeficiency virus type 1-specific [2',5'-bis-O-(tert- butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1",2"- oxathiole-2",2"-dioxide)-purine analogues show a resistance spectrum that is different from that of the human imm

artículo científico publicado en 1993

Human mitochondrial pyrophosphatase: cDNA cloning and analysis of the gene in patients with mtDNA depletion syndromes.

artículo científico publicado en 2005

Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity

artículo científico publicado en 2009

Hydroxyurea increases the phosphorylation of 3'-fluorothymidine and 3'-azidothymidine in CEM cells

artículo científico publicado en 1989

Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils

artículo científico publicado en 1999

Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein

artículo científico publicado en 1999

Identification of genes associated to 2',2'-difluorodeoxycytidine resistance in HeLa cells with a lentiviral short-hairpin RNA library

artículo científico publicado en 2011

Identification of the lysosomal membrane glycoprotein Lamp-1 as a receptor for type-1-fimbriated (mannose-specific) Escherichia coli.

artículo científico publicado en 1996

Identification of two active functional domains of human adenylate kinase 5.

artículo científico publicado en 2009

Immunostimulatory DNA induces degranulation and NADPH-oxidase activation in human neutrophils while concomitantly inhibiting chemotaxis and phagocytosis

artículo científico publicado en 2002

Immunostimulatory oligodeoxynucleotides induce dolphin neutrophil NADPH-oxidase activation in a CpG-independent but phosphorothioate backbone-dependent manner

artículo científico publicado en 2005

Improving the selectivity of acyclic nucleoside analogues as inhibitors of human mitochondrial thymidine kinase: replacement of a triphenylmethoxy moiety with substituted amines and carboxamides

artículo científico publicado en 2003

Incorporation of nucleoside analogs into nuclear or mitochondrial DNA is determined by the intracellular phosphorylation site

artículo científico publicado en 2000

Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome

artículo científico publicado en 2013

Increased mitochondrial DNA copy-number in CEM cells resistant to delayed toxicity of 2',3'-dideoxycytidine

artículo científico

Influence of acyclovir and bucyclovir on nucleotide pools in cells infected with herpes simplex virus type 1.

artículo científico publicado en 1986

Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose

artículo científico publicado en 2018

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells

artículo científico publicado en 2015

Inhibition of phospholipase A(2) abrogates intracellular processing of NADPH-oxidase derived reactive oxygen species in human neutrophils.

artículo científico publicado en 2012

Interleukin-8-derived peptide has antibacterial activity

artículo científico publicado en 2005

Interplay of HIV-1 phenotype and neutralizing antibody response in pathogenesis of AIDS

article

Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?

artículo científico publicado en 2010

Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication.

artículo científico publicado en 1998

Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway

artículo científico publicado en 2012

Investigation of the substrate recognition of Drosophila melanogaster nucleoside kinase by site directed mutagenesis

artículo científico publicado en 2004

Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate

artículo científico publicado en 2002

Is trichloroacetic acid an insufficient sample quencher of redox reactions?

artículo científico publicado en 2012

Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus.

artículo científico publicado en 1993

Lack of correlation between NADPH-oxidase priming and elevated alkaline phosphatase activity in cord blood neutrophils

artículo científico publicado en 1995

Late-onset respiratory failure due to TK2 mutations causing multiple mtDNA deletions.

artículo científico publicado en 2013

Ligand recognition and activation of formyl peptide receptors in neutrophils

artículo científico publicado en 2005

Lipid raft proteome of the human neutrophil azurophil granule

artículo científico publicado en 2007

Lipid-mediated protein delivery of suicide nucleoside kinases

artículo científico publicado en 2003

Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe

artículo científico publicado en 2001

Lipopolysaccharide-induced granule mobilization and priming of the neutrophil response to Helicobacter pylori peptide Hp(2-20), which activates formyl peptide receptor-like 1.

artículo científico publicado en 2002

Localization of the human deoxyguanosine kinase gene (DGUOK) to chromosome 2p13

artículo científico publicado en 1996

Long term expression of Drosophila melanogaster nucleoside kinase in thymidine kinase 2-deficient mice with no lethal effects caused by nucleotide pool imbalances

artículo científico publicado en 2014

Loss of thymidine kinase 2 alters neuronal bioenergetics and leads to neurodegeneration.

artículo científico publicado en 2010

MPO deficiency confers impaired processing of neutrophil reactive oxygen species in a patient with severe CRMO.

artículo científico publicado en 2015

Mammalian 5'(3')-deoxyribonucleotidase, cDNA cloning, and overexpression of the enzyme in Escherichia coli and mammalian cells

artículo científico publicado en 2000

Marked inhibitory activity of non-nucleoside reverse transcriptase inhibitors against human immunodeficiency virus type 1 when combined with (-)2',3'-dideoxy-3'-thiacytidine

artículo científico publicado en 1996

Measurement of respiratory burst products generated by professional phagocytes

artículo científico publicado en 2007

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes

artículo científico publicado en 2014

Mechanism of anti-HIV action of masked alaninyl d4T-MP derivatives

artículo científico publicado en 1996

Mitochondrial expression of the Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

artículo científico publicado en 2007

Mutational tuning of galectin-3 specificity and biological function

artículo científico publicado en 2010

N1-Substituted Thymine Derivatives as Mitochondrial Thymidine Kinase (TK-2) Inhibitors

scientific article published on 01 December 2006

NADPH-oxidase activation in murine neutrophils via formyl peptide receptors

artículo científico publicado en 2003

Nelarabine: a new purine analog in the treatment of hematologic malignancies.

artículo científico publicado en 2006

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species

artículo científico publicado en 2015

Neutrophil alkaline phosphatase activity increase in bacterial infections is not associated with a general increase in secretory vesicle membrane components.

artículo científico publicado en 1995

Neutrophil secretion induced by an intracellular Ca2+ rise and followed by whole-cell patch-clamp recordings occurs without any selective mobilization of different granule populations

artículo científico publicado en 2006

Neutrophil secretory vesicles are the intracellular reservoir for GPI-80, a protein with adhesion-regulating potential

artículo científico publicado en 2001

Neutrophils from patients with SAPHO syndrome show no signs of aberrant NADPH oxidase-dependent production of intracellular reactive oxygen species

artículo científico publicado en 2016

New ultrasensitive 32P-postlabelling method for the analysis of 3,N4-etheno-2'-deoxycytidine in human urine

artículo científico publicado en 2006

Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe

artículo científico publicado en 2004

Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase

artículo científico publicado en 2003

Novel ribofuranosylnucleoside lead compounds for potent and selective inhibitors of mitochondrial thymidine kinase-2

artículo científico publicado en 2000

Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity

artículo científico publicado en 2007

Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol

artículo científico publicado en 2001

Nucleoside diphosphate kinase. Investigation of the intersubunit contacts by site-directed mutagenesis and crystallography

artículo científico publicado en 1996

Nucleotide affinity for a stable phosphorylated intermediate of nucleoside diphosphate kinase

artículo científico publicado en 2002

On the road to discovery in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome ⬇️

artículo científico publicado el 2 de agosto de 2011

Oral candida albicans in HIV infection

artículo científico publicado en 1987

P02-025 - Homozygous Q705K sequence variant in NLRP3.

artículo científico publicado en 2013

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism

artículo científico publicado en 2015

PW03-003 – Altered neutrophil function in PFAPA.

artículo científico publicado en 2013

Pediatric chronic non-bacterial osteomyelitis in Goteborg, Sweden

artículo científico publicado en 2015

Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4

artículo científico publicado en 2002

Phagocyte interactions with Mycobacterium tuberculosis--Simultaneous analysis of phagocytosis, phagosome maturation and intracellular replication by imaging flow cytometry

artículo científico publicado en 2015

Phagocytosis following translocation of the neutrophil b-cytochrome from the specific granule to the plasma membrane is associated with an increased leakage of reactive oxygen species

artículo científico publicado en 1992

Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway

artículo científico publicado en 2017

Phosphorylation of 9-beta-D-arabinofuranosylguanine monophosphate by Drosophila melanogaster guanylate kinase

artículo científico publicado en 2005

Phosphorylation of anticancer nucleoside analogs by human mitochondrial deoxyguanosine kinase

artículo científico publicado en 1998

Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme

artículo científico publicado en 1999

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

artículo científico publicado en 2000

Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases

scientific journal article

Potent antitumoral effects of targeted promoter-driven oncolytic adenovirus armed with Dm-dNK for breast cancer in vitro and in vivo

artículo científico publicado en 2012

Priming of human neutrophils by mycobacterial lipoarabinomannans: role of granule mobilisation

artículo científico publicado en 2001

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

scientific journal article

Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori

artículo científico publicado en 2001

Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

artículo científico publicado en 1994

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry

artículo científico publicado en 2015

Reactivation of desensitized formyl peptide receptors by platelet activating factor: a novel receptor cross talk mechanism regulating neutrophil superoxide anion production

artículo científico publicado en 2013

Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium

artículo científico publicado en 2003

Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications

artículo científico

Reduced levels of mitochondrial DNA increases the toxicity of 9-beta-D-arabinofuranosylguanine (araG).

artículo científico publicado en 2008

Regulation of interleukin-4 signaling by extracellular reduction of intramolecular disulfides

artículo científico publicado en 2009

Regulation of neutrophil apoptosis differs after in vivo transmigration to skin chambers and synovial fluid: a role for inflammasome-dependent interleukin-1β release.

artículo científico publicado en 2013

Replicative capacity of human immunodeficiency virus from patients with varying severity of HIV infection

artículo científico publicado en 1986

Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720

artículo científico publicado en 1994

Respiratory burst in human neutrophils

artículo científico publicado en 1999

Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools.

artículo científico publicado en 1994

Retained sensitivity to cytotoxic pyrimidine nucleoside analogs in thymidine kinase 2 deficient human fibroblasts

artículo científico publicado en 2010

Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.

artículo científico publicado en 2000

Retrovirus-mediated Drosophila melanogaster multisubstrate deoxyribonucleoside kinase gene therapy of gastric cancer cells in vitro and in vivo.

artículo científico publicado en 2010

Reverse transcriptase fidelity and HIV-1 variation

artículo científico publicado en 1997

Review of autoinflammatory diseases, with a special focus on periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome

artículo científico publicado en 2016

Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes

artículo científico publicado en 1996

Sensitivity of (138 Glu-->Lys) mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to HIV-1-specific RT inhibitors

artículo científico publicado en 1994

Sensitivity to inhibition by beta-chemokines correlates with biological phenotypes of primary HIV-1 isolates

artículo científico publicado en 1996

Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1.

artículo científico publicado en 2007

Severe chronic non-bacterial osteomyelitis associated with MPO deficiency

artículo científico publicado en 2014

Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design

artículo científico publicado en 2006

Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases

scientific journal article

Substrate specificity of feline and canine herpesvirus thymidine kinase

artículo científico publicado en 2008

Substrate specificity of mitochondrial 2'-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine

artículo científico publicado en 1993

Substrate specificity of three viral thymidine kinases (TK): vaccinia virus TK, feline herpesvirus TK, and canine herpesvirus TK.

artículo científico publicado en 2006

Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives)

artículo científico publicado en 1995

Surface-related triggering of the neutrophil respiratory burst. Characterization of the response induced by IgG adsorbed to hydrophilic and hydrophobic glass surfaces

scientific article published on 01 July 1997

Synthesis and Comparative Molecular Field Analysis (CoMFA) of Symmetric and Nonsymmetric Cyclic Sulfamide HIV-1 Protease Inhibitors

article

Synthesis and comparative molecular field analysis (CoMFA) of symmetric and nonsymmetric cyclic sulfamide HIV-1 protease inhibitors

artículo científico publicado en 2001

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes

artículo científico publicado en 2004

Synthesis, Cytostatic Activity and Inhibition of Ribonucleotide Reductase by 5′-Phosphoramidates and 5′-Diphosphates, of 2′-O-Allyl-arabinofuranosyl Nucleosides

scientific article published on 01 April 1999

Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors

artículo científico publicado en 2010

TSAO Derivatives: Highly Specific Inhibitors of Human Immunodeficiency Virus Type-1 (HIV-1) Replication

article

Tanshinone IIA enhances bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in nuclei and mitochondria

artículo científico publicado en 2015

The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition

artículo científico publicado en 2016

The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal

artículo científico publicado en 2003

The HIV replication inhibitor 3'-fluoro-3'-deoxythymidine blocks sialylation of N-linked oligosaccharides

artículo científico publicado en 1992

The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase

artículo científico publicado en 2016

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the a

artículo científico publicado en 2008

The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes

artículo científico publicado en 2011

The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture

artículo científico publicado en 2006

The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase

artículo científico publicado en 2013

The human neutrophil subsets defined by the presence or absence of OLFM4 both transmigrate into tissue in vivo and give rise to distinct NETs in vitro

artículo científico publicado en 2013

The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase

artículo científico publicado en 2000

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop

artículo científico publicado en 2013

The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils

artículo científico publicado en 1995

The many isoforms of human adenylate kinases

artículo científico publicado en 2014

The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8.

artículo científico publicado en 2004

The mitochondrial carrier SLC25A10 regulates cancer cell growth

artículo científico publicado en 2015

The multifunctional deoxynucleoside kinase of insect cells is a target for the development of new insecticides

artículo científico publicado en 2000

The multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster as a therapeutic suicide gene of breast cancer cells

artículo científico publicado en 2011

The phagocyte chemiluminescence paradox: luminol can act as an inhibitor of neutrophil NADPH-oxidase activity

artículo científico publicado en 1999

The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.

artículo científico publicado en 2004

The presence of stomatin in detergent-insoluble domains of neutrophil granule membranes

artículo científico publicado en 2002

The subcellular location of nucleoside analog phosphorylation is a determinant of synergistic effects of hydroxyurea.

artículo científico publicado en 2000

The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor

artículo científico publicado en 2000

The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2

artículo científico publicado en 2001

The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide

artículo científico publicado en 2004

Thioredoxin-1 and protein disulfide isomerase catalyze the reduction of similar disulfides in HIV gp120.

artículo científico publicado en 2012

Thymidine kinase 2 deficiency-induced mtDNA depletion in mouse liver leads to defect β-oxidation

artículo científico publicado en 2013

Toward an Inclusive, Congruent, and Precise Definition of Autoinflammatory Diseases

artículo científico publicado en 2017

Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency

artículo científico publicado en 2013

Treatment of human immunodeficiency virus type 1 (HIV-1)-infected cells with combinations of HIV-1-specific inhibitors results in a different resistance pattern than does treatment with single-drug therapy.

artículo científico publicado en 1993

Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion

artículo científico publicado en 2010

Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis

artículo científico publicado en 2005

[Familial Mediterranean fever – an important disease in a globalised world].

artículo científico publicado en 2016

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