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Lista de obras de Seiji Watanabe

A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis

artículo científico publicado en 2018

ALS-linked TDP-43M337V knock-in mice exhibit splicing deregulation without neurodegeneration

scientific article published on 20 January 2020

Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43

artículo científico publicado en 2020

Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with the neuroprotective functions of microglia and T cells

artículo científico publicado en 2015

Chimeric ZHHH neuroglobin acts as a cell membrane-penetrating inducer of neurite outgrowth.

artículo científico publicado en 2017

Crucial roles of Glu60 in human neuroglobin as a guanine nucleotide dissociation inhibitor and neuroprotective agent

artículo científico publicado en 2013

Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity

artículo científico publicado en 2014

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life

artículo científico publicado en 2014

Functional characterization of fish neuroglobin: zebrafish neuroglobin is highly expressed in amacrine cells after optic nerve injury and can translocate into ZF4 cells.

artículo científico publicado en 2013

Human neuroglobin functions as an oxidative stress-responsive sensor for neuroprotection

artículo científico publicado en 2012

Identification of residues critical for the cell-membrane-penetrating activity of zebrafish neuroglobin

artículo científico publicado en 2010

Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis

artículo científico publicado en 2017

Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes.

artículo científico publicado en 2018

Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice

artículo científico publicado en 2018

Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model

article

Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway

scientific article published on 25 July 2019

Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS

artículo científico publicado en 2016

Module M1 of zebrafish neuroglobin acts as a structural and functional protein building block for a cell-membrane-penetrating activity

artículo científico publicado en 2011

Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.

artículo científico publicado en 2016

Neuroprotective function of human neuroglobin is correlated with its guanine nucleotide dissociation inhibitor activity

artículo científico publicado en 2008

SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system

artículo científico publicado en 2014

Species-specific functional evolution of neuroglobin

artículo científico publicado el 1 de abril de 2011

TDP-43 accelerates age-dependent degeneration of interneurons

artículo científico publicado en 2017

Zebrafish neuroglobin is a cell-membrane-penetrating globin.

artículo científico publicado en 2008

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