Lista de obras - Dongsheng Duan - Dominio Público Uruguay

100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy.

artículo científico publicado en 2016

A New Kid on the Playground of CRISPR DMD Therapy.

artículo científico publicado en 2017

A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation

artículo científico publicado en 2000

A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs.

artículo científico publicado en 2008

AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in >21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy cardiomyopathy.

artículo científico publicado en 2012

AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart.

artículo científico publicado en 2015

AAV-microdystrophin therapy improves cardiac performance in aged female mdx mice.

artículo científico publicado en 2011

Adeno-associated virus serotype-9 mediated retinal outer plexiform layer transduction is mainly through the photoreceptors

artículo científico publicado en 2010

Adeno-associated virus serotype-9 microdystrophin gene therapy ameliorates electrocardiographic abnormalities in mdx mice.

artículo científico publicado en 2008

Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

artículo científico publicado en 2005

Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress

artículo científico publicado en 2004

Adenovirus-mediated gene transfer to adult mouse cardiomyocytes is selectively influenced by culture medium

artículo científico publicado en 2003

Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs ⬇️

artículo científico publicado en 2011

An improved method for studying mouse diaphragm function

artículo científico publicado en 2019

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

artículo científico publicado en 2015

Automatic quantification of microscopic heart damage in a mouse model of Duchenne muscular dystrophy using optical polarization tractography.

artículo científico publicado en 2018

C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice

artículo científico publicado en 2006

CRISPR-Cas9 cleavage efficiency correlates strongly with target-sgRNA folding stability: from physical mechanism to off-target assessment

artículo científico publicado en 2017

Cardiac expression of a mini-dystrophin that normalizes skeletal muscle force only partially restores heart function in aged Mdx mice.

artículo científico publicado en 2008

Catalase overexpression does not impair extensor digitorum longus muscle function in normal mice.

artículo científico publicado en 2007

Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy.

artículo científico publicado en 2006

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot

artículo científico publicado en 2014

Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy

artículo científico publicado en 2015

Design of trans-splicing adeno-associated viral vectors for Duchenne muscular dystrophy gene therapy

artículo científico publicado en 2008

Double strand interaction is the predominant pathway for intermolecular recombination of adeno-associated viral genomes

scientific article published on 01 August 2003

Duchenne muscular dystrophy gene therapy in the canine model.

artículo científico publicado en 2015

Dystrophin Gene Replacement and Gene Repair Therapy for Duchenne Muscular Dystrophy in 2016: An Interview

artículo científico publicado en 2016

Dystrophin contains multiple independent membrane-binding domains.

artículo científico publicado en 2016

Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy

artículo científico publicado en 2012

Dystrophin knockdown mice suggest that early, transient dystrophin expression might be enough to prevent later pathology

artículo científico publicado en 2008

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.

artículo científico publicado en 2009

Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al.

artículo científico publicado en 2015

Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.

artículo científico publicado en 2009

Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors

scientific article published on 01 June 2007

Efficient whole-body transduction with trans-splicing adeno-associated viral vectors

artículo científico publicado en 2007

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

artículo científico publicado en 2000

Enhancement of muscle gene delivery with pseudotyped adeno-associated virus type 5 correlates with myoblast differentiation.

artículo científico publicado en 2001

Evaluation of muscle function of the extensor digitorum longus muscle ex vivo and tibialis anterior muscle in situ in mice.

artículo científico publicado en 2013

Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison

artículo científico publicado en 2001

Expanding adeno-associated viral vector capacity: a tale of two vectors.

scientific article published on January 2007

Full-length dystrophin reconstitution with adeno-associated viral vectors

artículo científico publicado en 2014

Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle.

artículo científico publicado en 2012

Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy.

artículo científico publicado en 2010

Gene delivery to the heart: an updated review on vectors and methods

scientific article published on 01 October 2011

Genomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotype

scientific article published on 22 April 2016

Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction

artículo científico publicado en 2010

Heart structural remodeling in a mouse model of Duchenne cardiomyopathy revealed using optical polarization tractography [Invited].

artículo científico publicado en 2017

High resolution imaging of the fibrous microstructure in bovine common carotid artery using optical polarization tractography

artículo científico publicado en 2015

Histology validation of mapping depth-resolved cardiac fiber orientation in fresh mouse heart using optical polarization tractography

artículo científico publicado en 2014

Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs

artículo científico publicado en 2012

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

artículo científico publicado en 2015

Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo.

artículo científico publicado en 2000

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.

artículo científico publicado en 2011

Mapping 3D fiber orientation in tissue using dual-angle optical polarization tractography

artículo científico publicado en 2016

Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice

artículo científico publicado en 2010

Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy

artículo científico publicado en 2013

Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart.

artículo científico publicado en 2003

Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy

artículo científico publicado en 2002

Monitoring Murine Skeletal Muscle Function for Muscle Gene Therapy ⬇️

artículo científico publicado el 1 de enero de 2011

Nanotherapy for Duchenne muscular dystrophy

artículo científico publicado en 2017

Night Activity Reduction is a Signature Physiological Biomarker for Duchenne Muscular Dystrophy Dogs

artículo científico publicado en 2015

Nitric oxide-dependent attenuation of noradrenaline-induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy

scientific article published on 20 September 2018

Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin-null mice

artículo científico publicado en 2010

Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography

artículo científico publicado en 2017

Nondestructive imaging of fiber structure in articular cartilage using optical polarization tractography

artículo científico publicado en 2016

Optical polarization tractography revealed significant fiber disarray in skeletal muscles of a mouse model for Duchenne muscular dystrophy

artículo científico publicado en 2015

Partial restoration of cardiac function with ΔPDZ nNOS in aged mdx model of Duchenne cardiomyopathy

artículo científico publicado en 2014

Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy

artículo científico publicado en 2015

Perspectives on best practices for gene therapy programs

artículo científico publicado en 2015

Phenotyping cardiac gene therapy in mice

artículo científico publicado en 2011

Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia.

artículo científico publicado en 1998

Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression

artículo científico publicado en 2007

Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy

artículo científico publicado en 2015

Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring

artículo científico publicado en 2013

Recombinant AAV-mediated gene delivery using dual vector heterodimerization.

artículo científico publicado en 2002

Recombinant adeno-associated viral vector production and purification.

artículo científico publicado en 2012

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

artículo científico publicado en 2017

Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus.

artículo científico publicado en 2015

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.

artículo científico publicado en 2010

Standard Operating Procedures (SOPs) for Evaluating the Heart in Preclinical Studies of Duchenne Muscular Dystrophy

artículo científico publicado en 2015

Structural analysis of adeno-associated virus transduction circular intermediates.

artículo científico publicado en 1999

Sub-physiological sarcoglycan expression contributes to compensatory muscle protection in mdx mice

artículo científico publicado en 2009

Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors.

artículo científico publicado en 2006

Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration

artículo científico publicado en 2007

Systemic delivery of adeno-associated viral vectors

artículo científico publicado en 2016

Systemic gene transfer reveals distinctive muscle transduction profile of tyrosine mutant AAV-1, -6, and -9 in neonatal dogs.

artículo científico publicado en 2014

The FVB Background Does Not Dramatically Alter the Dystrophic Phenotype of Mdx Mice

artículo científico publicado en 2015

The evolution of heart gene delivery vectors

artículo científico publicado en 2011

The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice

artículo científico publicado en 2011

Truncated dystrophins reduce muscle stiffness in the extensor digitorum longus muscle of mdx mice.

artículo científico publicado en 2012

Two independent molecular pathways for recombinant adeno-associated virus genome conversion occur after UV-C and E4orf6 augmentation of transduction

artículo científico publicado en 1999

Unified energetics analysis unravels SpCas9 cleavage activity for optimal gRNA design

artículo científico publicado en 2019

Uniform low-level dystrophin expression in the heart partially preserved cardiac function in an aged mouse model of Duchenne cardiomyopathy

artículo científico publicado en 2016

Whole Body Skeletal Muscle Transduction in Neonatal Dogs with AAV-9 ⬇️

artículo científico publicado el 1 de enero de 2011

Lista de obras de Dongsheng Duan

100-fold but not 50-fold dystrophin overexpression aggravates electrocardiographic defects in the mdx model of Duchenne muscular dystrophy.

A New Kid on the Playground of CRISPR DMD Therapy.

A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation

A single intravenous injection of adeno-associated virus serotype-9 leads to whole body skeletal muscle transduction in dogs.

AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in >21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy cardiomyopathy.

AAV-8 is more efficient than AAV-9 in transducing neonatal dog heart.

AAV-microdystrophin therapy improves cardiac performance in aged female mdx mice.

Adeno-associated virus serotype-9 mediated retinal outer plexiform layer transduction is mainly through the photoreceptors

Adeno-associated virus serotype-9 microdystrophin gene therapy ameliorates electrocardiographic abnormalities in mdx mice.

Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury.

Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress

Adenovirus-mediated gene transfer to adult mouse cardiomyocytes is selectively influenced by culture medium

Age-matched comparison reveals early electrocardiography and echocardiography changes in dystrophin-deficient dogs ⬇️

An improved method for studying mouse diaphragm function

Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

Automatic quantification of microscopic heart damage in a mouse model of Duchenne muscular dystrophy using optical polarization tractography.

C-terminal-truncated microdystrophin recruits dystrobrevin and syntrophin to the dystrophin-associated glycoprotein complex and reduces muscular dystrophy in symptomatic utrophin/dystrophin double-knockout mice

CRISPR-Cas9 cleavage efficiency correlates strongly with target-sgRNA folding stability: from physical mechanism to off-target assessment

Cardiac expression of a mini-dystrophin that normalizes skeletal muscle force only partially restores heart function in aged Mdx mice.

Catalase overexpression does not impair extensor digitorum longus muscle function in normal mice.

Challenges and opportunities in dystrophin-deficient cardiomyopathy gene therapy.

Characterization of 65 epitope-specific dystrophin monoclonal antibodies in canine and murine models of duchenne muscular dystrophy by immunostaining and western blot

Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy

Design of trans-splicing adeno-associated viral vectors for Duchenne muscular dystrophy gene therapy

Double strand interaction is the predominant pathway for intermolecular recombination of adeno-associated viral genomes

Duchenne muscular dystrophy gene therapy in the canine model.

Dystrophin Gene Replacement and Gene Repair Therapy for Duchenne Muscular Dystrophy in 2016: An Interview

Dystrophin contains multiple independent membrane-binding domains.

Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy

Dystrophin knockdown mice suggest that early, transient dystrophin expression might be enough to prevent later pathology

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy.

Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al.

Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.

Efficient Whole-body Transduction with Trans-splicing Adeno-associated Viral Vectors

Efficient whole-body transduction with trans-splicing adeno-associated viral vectors

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

Enhancement of muscle gene delivery with pseudotyped adeno-associated virus type 5 correlates with myoblast differentiation.

Evaluation of muscle function of the extensor digitorum longus muscle ex vivo and tibialis anterior muscle in situ in mice.

Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison

Expanding adeno-associated viral vector capacity: a tale of two vectors.

Full-length dystrophin reconstitution with adeno-associated viral vectors

Gender differences in contractile and passive properties of mdx extensor digitorum longus muscle.

Gender influences cardiac function in the mdx model of Duchenne cardiomyopathy.

Gene delivery to the heart: an updated review on vectors and methods

Genomic removal of a therapeutic mini-dystrophin gene from adult mice elicits a Duchenne muscular dystrophy-like phenotype

Genotyping mdx, mdx3cv, and mdx4cv mice by primer competition polymerase chain reaction

Heart structural remodeling in a mouse model of Duchenne cardiomyopathy revealed using optical polarization tractography [Invited].

High resolution imaging of the fibrous microstructure in bovine common carotid artery using optical polarization tractography

Histology validation of mapping depth-resolved cardiac fiber orientation in fresh mouse heart using optical polarization tractography

Humoral immunity to AAV-6, 8, and 9 in normal and dystrophic dogs

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Incorporation of adeno-associated virus in a calcium phosphate coprecipitate improves gene transfer to airway epithelia in vitro and in vivo.

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.

Mapping 3D fiber orientation in tissue using dual-angle optical polarization tractography

Marginal level dystrophin expression improves clinical outcome in a strain of dystrophin/utrophin double knockout mice

Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy

Microdystrophin gene therapy of cardiomyopathy restores dystrophin-glycoprotein complex and improves sarcolemma integrity in the mdx mouse heart.

Modular flexibility of dystrophin: implications for gene therapy of Duchenne muscular dystrophy

Monitoring Murine Skeletal Muscle Function for Muscle Gene Therapy ⬇️

Nanotherapy for Duchenne muscular dystrophy

Night Activity Reduction is a Signature Physiological Biomarker for Duchenne Muscular Dystrophy Dogs

Nitric oxide-dependent attenuation of noradrenaline-induced vasoconstriction is impaired in the canine model of Duchenne muscular dystrophy

Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin-null mice

Non-invasive evaluation of muscle disease in the canine model of Duchenne muscular dystrophy by electrical impedance myography

Nondestructive imaging of fiber structure in articular cartilage using optical polarization tractography

Optical polarization tractography revealed significant fiber disarray in skeletal muscles of a mouse model for Duchenne muscular dystrophy

Partial restoration of cardiac function with ΔPDZ nNOS in aged mdx model of Duchenne cardiomyopathy

Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy

Perspectives on best practices for gene therapy programs

Phenotyping cardiac gene therapy in mice

Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia.

Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression

Prospect of gene therapy for cardiomyopathy in hereditary muscular dystrophy

Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring

Recombinant AAV-mediated gene delivery using dual vector heterodimerization.

Recombinant adeno-associated viral vector production and purification.

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice

Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus.

Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin.