Lista de obras - Salvatore Valitutti - Dominio Público Uruguay

A biased competition theory of cytotoxic T lymphocyte interaction with tumor nodules

artículo científico publicado en 2015

A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.

artículo científico publicado en 2016

A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells

artículo científico publicado en 2013

Activation of the ancestral polarity regulator protein kinase C zeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs

scientific article published on 02 August 2010

Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation

artículo científico publicado en 1997

Alterations in thymocyte subpopulations in Down's syndrome (trisomy 21).

artículo científico publicado en 1988

An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse.

artículo científico publicado en 2013

Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics.

artículo científico publicado en 2006

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

artículo científico publicado en 2002

CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment

scientific article published on 16 February 2007

CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse.

artículo científico publicado en 2007

CD4+ T cells downregulate Bcl-2 in germinal centers

artículo científico publicado en 2005

Cell-cell cooperation at the T helper cell/mast cell immunological synapse

artículo científico publicado en 2009

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes

artículo científico publicado en 2015

Cognate interactions between mast cells and helper T lymphocytes

artículo científico publicado en 2010

Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses.

artículo científico publicado en 2006

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

artículo científico publicado en 1997

Different activation signals induce distinct mast cell degranulation strategies

artículo científico publicado en 2016

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

artículo científico publicado en 1996

Direct monitoring of basophil degranulation by using avidin-based probes

artículo científico publicado en 2017

Distinct signaling properties identify functionally different CD4 epitopes.

artículo científico publicado en 1995

Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study

artículo científico publicado en 2011

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

artículo científico publicado en 2008

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

artículo científico publicado en 2000

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

artículo científico publicado en 2000

Frequency encoding of T-cell receptor engagement dynamics in calcium time series.

artículo científico publicado en 2004

HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes.

artículo científico publicado en 1998

Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype

artículo científico publicado en 2013

Human regulatory T cells inhibit polarization of T helper cells toward antigen-presenting cells via a TGF-beta-dependent mechanism

artículo científico publicado en 2008

Hydroxychloroquine as a novel therapeutic approach in mast cell activation diseases

artículo científico publicado en 2018

IL-33 fine tunes mast cell degranulation and chemokine production at the single-cell level

artículo científico publicado en 2016

Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes

artículo científico publicado en 2022

Immunological synapse: center of attention again

artículo científico publicado en 2008

Immunological synapses are versatile structures enabling selective T cell polarization.

artículo científico publicado en 2005

Impaired functional responses in follicular lymphoma CD8+TIM-3+ T lymphocytes following TCR engagement.

artículo científico publicado en 2016

Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing.

artículo científico publicado en 2015

Kinetics and extent of protein tyrosine kinase activation in individual T cells upon antigenic stimulation

artículo científico publicado en 1999

Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels

artículo científico publicado en 2013

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold

artículo científico publicado en 2003

Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence.

artículo científico publicado en 2015

Measurement of calcium mobilization responses in killer cell/target conjugates by FACS analysis

artículo científico publicado en 2000

Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse

artículo científico publicado en 2016

Multiparametric analysis of CD8 T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy

scientific article published on 07 February 2019

New insights to the functional role of the T cell-antigen presenting cell immunological synapse

artículo científico publicado en 2002

New roles and controls of mast cells.

artículo científico publicado en 2017

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

artículo científico publicado en 1995

Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.

artículo científico publicado en 1999

Plasticity of immunological synapses.

artículo científico publicado en 2010

Platelet-activating factor (PAF) receptor antagonists inhibit mitogen-induced human peripheral blood T-cell proliferation

scientific article published on 01 October 1987

Reciprocal polarization of T and B cells at the immunological synapse

artículo científico publicado en 2011

Reply: To PMID 23518141.

artículo científico publicado en 2013

Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility.

artículo científico publicado en 1993

Sequential adjustment of cytotoxic T lymphocyte densities improves efficacy in controlling tumor growth

scientific article published on 23 August 2019

Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates

scientific article published on 01 September 1996

Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes

artículo científico publicado en 2011

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

artículo científico publicado en 2020

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

artículo científico publicado en 1995

T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse

scientific article published on 20 November 2004

T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC

artículo científico publicado en 2009

TCR dynamics on the surface of living T cells

artículo científico publicado en 2001

The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy

artículo científico publicado en 2012

The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse.

artículo científico publicado en 2018

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

artículo científico publicado en 2011

The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets.

artículo científico publicado en 2010

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

artículo científico publicado en 2003

The diversity of immunological synapses.

artículo científico publicado en 2003

The space and time frames of T cell activation at the immunological synapse ⬇️

artículo científico publicado el 14 de octubre de 2010

Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells

artículo científico publicado en 2019

Tuning of T cell clone size and activation threshold by control of CD25 expression through mitogen-activated protein kinase pathways

artículo científico publicado en 2002

Wiskott-Aldrich syndrome protein controls antigen-presenting cell-driven CD4+ T-cell motility by regulating adhesion to intercellular adhesion molecule-1

artículo científico publicado en 2012

Lista de obras de Salvatore Valitutti

A biased competition theory of cytotoxic T lymphocyte interaction with tumor nodules

A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.

A single peptide-major histocompatibility complex ligand triggers digital cytokine secretion in CD4(+) T cells

Activation of the ancestral polarity regulator protein kinase C zeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs

Agonist-induced T cell receptor down-regulation: molecular requirements and dissociation from T cell activation

Alterations in thymocyte subpopulations in Down's syndrome (trisomy 21).

An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse.

Analysis of peptide/MHC-induced TCR downregulation: deciphering the triggering kinetics.

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

CD160-activating NK cell effector functions depend on the phosphatidylinositol 3-kinase recruitment

CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse.

CD4+ T cells downregulate Bcl-2 in germinal centers

Cell-cell cooperation at the T helper cell/mast cell immunological synapse

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8(+) T Lymphocytes

Cognate interactions between mast cells and helper T lymphocytes

Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses.

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

Different activation signals induce distinct mast cell degranulation strategies

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

Direct monitoring of basophil degranulation by using avidin-based probes

Distinct signaling properties identify functionally different CD4 epitopes.

Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study

Effects of intracellular calcium and actin cytoskeleton on TCR mobility measured by fluorescence recovery

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

Frequency encoding of T-cell receptor engagement dynamics in calcium time series.

HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta T lymphocytes.

Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype

Human regulatory T cells inhibit polarization of T helper cells toward antigen-presenting cells via a TGF-beta-dependent mechanism

Hydroxychloroquine as a novel therapeutic approach in mast cell activation diseases

IL-33 fine tunes mast cell degranulation and chemokine production at the single-cell level

Identification of distinct cytotoxic granules as the origin of supramolecular attack particles in T lymphocytes

Immunological synapse: center of attention again

Immunological synapses are versatile structures enabling selective T cell polarization.

Impaired functional responses in follicular lymphoma CD8+TIM-3+ T lymphocytes following TCR engagement.

Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing.

Kinetics and extent of protein tyrosine kinase activation in individual T cells upon antigenic stimulation

Lymphatic endothelium forms integrin-engaging 3D structures during DC transit across inflamed lymphatic vessels

Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold

Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence.

Measurement of calcium mobilization responses in killer cell/target conjugates by FACS analysis

Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse

Multiparametric analysis of CD8 T cell compartment phenotype in chronic lymphocytic leukemia reveals a signature associated with progression toward therapy

New insights to the functional role of the T cell-antigen presenting cell immunological synapse

New roles and controls of mast cells.

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.

Plasticity of immunological synapses.

Platelet-activating factor (PAF) receptor antagonists inhibit mitogen-induced human peripheral blood T-cell proliferation

Reciprocal polarization of T and B cells at the immunological synapse

Reply: To PMID 23518141.

Role of cAMP in regulating cytotoxic T lymphocyte adhesion and motility.

Sequential adjustment of cytotoxic T lymphocyte densities improves efficacy in controlling tumor growth

Signal extinction and T cell repolarization in T helper cell-antigen-presenting cell conjugates

Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes

Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

T-cell activation is accompanied by an ubiquitination process occurring at the immunological synapse

T-cell antagonism by short half-life pMHC ligands can be mediated by an efficient trapping of T-cell polarization toward the APC

TCR dynamics on the surface of living T cells

The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy

The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse.

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets.

The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation

The diversity of immunological synapses.

The space and time frames of T cell activation at the immunological synapse ⬇️

Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells

Tuning of T cell clone size and activation threshold by control of CD25 expression through mitogen-activated protein kinase pathways

Wiskott-Aldrich syndrome protein controls antigen-presenting cell-driven CD4+ T-cell motility by regulating adhesion to intercellular adhesion molecule-1