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Lista de obras de Ophir D Klein

A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

scientific article published in 2023

A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage

scientific article published on 02 September 2019

Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation

artículo científico publicado en 2013

Acute fatal presentation of ornithine transcarbamylase deficiency in a previously healthy male.

scientific article published on 07 May 2008

An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

artículo científico publicado en 2017

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery

artículo científico publicado en 2018

Assessment of endometrial volume by three-dimensional ultrasound prior to embryo transfer: clues to endometrial receptivity

scientific article published on 01 November 1999

Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration

artículo científico publicado en 2019

BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor

artículo científico publicado en 2012

BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor.

artículo científico publicado en 2013

Brachydactylic multiple delta phalanges plus syndrome

scientific article published on 01 September 2005

Case report: Y;6 translocation with deletion of 6p.

artículo científico publicado en 2005

Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid.

artículo científico publicado en 2017

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.

artículo científico publicado en 2018

Characterization of X-linked hypohidrotic ectodermal dysplasia (XL-HED) hair and sweat gland phenotypes using phototrichogram analysis and live confocal imaging.

artículo científico publicado en 2013

Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms.

artículo científico publicado en 2012

Continuously growing rodent molars result from a predictable quantitative evolutionary change over 50 million years

artículo científico publicado en 2015

Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia.

artículo científico publicado en 2013

Craniofacial and dental development in Costello syndrome.

artículo científico publicado en 2014

Craniofacial morphometric analysis of individuals with X-linked hypohidrotic ectodermal dysplasia.

artículo científico publicado en 2014

Crosstalk between miR-34a and Notch Signaling Promotes Differentiation in Apical Papilla Stem Cells (SCAPs).

artículo científico publicado en 2014

Current trends in stem cell therapy for improvement of bone quality.

artículo científico publicado en 2013

DLX4 is associated with orofacial clefting and abnormal jaw development.

artículo científico publicado en 2015

Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth

scientific article published on 23 September 2020

Dental findings in 14q terminal deletion syndrome.

artículo científico publicado en 2014

Dental, Oral, and Craniofacial Regenerative Medicine: Transforming Biotechnologies for Innovating Patient Care

artículo científico publicado en 2018

Developing physician-scientists in the fields of neonatology and pediatric critical care medicine: an effort to formulate a departmental policy

artículo científico publicado en 2013

Developmental disorders of the dentition: an update

scientific article published on 04 October 2013

Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar

artículo científico publicado en 2019

Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis

artículo científico publicado en 2016

EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells.

artículo científico publicado en 2017

EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids

scientific article published in 2023

Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors

scientific journal article

Engineering synthetic morphogen systems that can program multicellular patterning

scientific article published on 01 October 2020

Expression of FGFs during early mouse tongue development

artículo científico publicado en 2015

Expression of microRNAs in the stem cell niche of the adult mouse incisor.

artículo científico publicado en 2011

FGF signaling refines Wnt gradients to regulate the patterning of taste papillae.

artículo científico publicado en 2017

FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size.

artículo científico publicado en 2011

FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells.

artículo científico publicado en 2018

Fibroblast growth factor signaling in mammalian tooth development

artículo científico

From molecules to mastication: the development and evolution of teeth

artículo científico publicado en 2013

Further supporting evidence for theSATB2-associated syndrome found through whole exome sequencing

scientific article published on 01 May 2015

Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology

artículo científico publicado en 2016

Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape.

artículo científico publicado en 2016

Genomic variants of ATF3 in patients with hypospadias.

artículo científico publicado en 2008

Genotype-phenotype analysis of the branchio-oculo-facial syndrome

artículo científico publicado en 2011

Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor

artículo científico publicado en 2010

Human Facial Shape and Size Heritability and Genetic Correlations

artículo científico publicado en 2016

Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome

artículo científico publicado en 2016

Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice

artículo científico publicado en 2015

Identification of novel Fgf enhancers and their role in dental evolution

artículo científico publicado en 2016

If a stem cell dies in the crypt, and no one is around to see it….

artículo científico publicado en 2013

In vitro generation of human pluripotent stem cell derived lung organoids

artículo científico publicado en 2015

In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development.

scientific article published on 07 December 2016

Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium.

artículo científico publicado en 2014

Inductive ability of human developing and differentiated dental mesenchyme

artículo científico publicado en 2013

Inflation-collapse dynamics drive patterning and morphogenesis in intestinal organoids

artículo científico publicado en 2021

Inhibition of Notch Signaling During Mouse Incisor Renewal Leads to Enamel Defects

artículo científico publicado en 2015

Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

artículo científico publicado en 2010

Injectable bone tissue engineering using expanded mesenchymal stem cells

artículo científico publicado en 2013

Interstitial deletion of chromosome 12q: genotype-phenotype correlation of two patients utilizing array comparative genomic hybridization

artículo científico publicado en 2005

Interstitial deletions of chromosome 6q: genotype-phenotype correlation utilizing array CGH.

artículo científico publicado en 2007

Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif

artículo científico publicado en 2017

Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor

artículo científico publicado en 2017

Isolation and culture of dental epithelial stem cells from the adult mouse incisor.

artículo científico publicado en 2014

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

artículo científico publicado en 2018

Lgr5+ telocytes are a signaling source at the intestinal villus tip

scientific article published on 22 April 2020

Lineage tracing of epithelial cells in developing teeth reveals two strategies for building signaling centers

artículo científico publicado en 2017

Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis

artículo científico publicado en 2015

Modulation of Fgf3 dosage in mouse and men mirrors evolution of mammalian dentition

artículo científico publicado en 2009

Molecular and cellular mechanisms of tooth development, homeostasis and repair

artículo científico publicado en 2020

Mutational analysis of the catalytic residues lysine 230 and tyrosine 160 in the NADP(+)-dependent isocitrate dehydrogenase from Escherichia coli

scientific article published on 01 January 1995

Mutations of CXorf6 are associated with a range of severities of hypospadias

artículo científico publicado en 2008

Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells.

artículo científico publicado en 2014

On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells

artículo científico publicado en 2014

Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis.

artículo científico publicado en 2015

Oral epithelial stem cells in tissue maintenance and disease: the first steps in a long journey.

artículo científico publicado en 2013

PERP regulates enamel formation via effects on cell-cell adhesion and gene expression

scientific journal article

Phenotypic and evolutionary implications of modulating the ERK-MAPK cascade using the dentition as a model

artículo científico publicado en 2015

Prenatal β-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors.

artículo científico publicado en 2016

Prominin-1 controls stem cell activation by orchestrating ciliary dynamics

artículo científico publicado en 2018

Publisher Correction: FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells

scientific article published in Nature Communications

Ras Signaling Regulates Stem Cells and Amelogenesis in the Mouse Incisor

artículo científico publicado en 2017

Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling

artículo científico publicado en 2011

Replaying evolutionary transitions from the dental fossil record

artículo científico publicado en 2014

Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis

artículo científico publicado en 2017

Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation.

artículo científico publicado en 1998

SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis

artículo científico publicado en 2018

SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling.

artículo científico publicado en 2016

Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor

artículo científico publicado en 2014

Shh expression in a rudimentary tooth offers new insights into development of the mouse incisor

artículo científico publicado en 2011

Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors.

artículo científico publicado en 2010

Sonic Hedgehog Signaling Is Required for Cyp26 Expression during Embryonic Development. ⬇️

artículo científico publicado en 2019

Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.

artículo científico publicado en 2016

Sox2 marks epithelial competence to generate teeth in mammals and reptiles

artículo científico publicado en 2013

Spontaneous emergence of overgrown molar teeth in a colony of Prairie voles (Microtus ochrogaster)

artículo científico publicado en 2015

Sprouty genes regulate proliferation and survival of human embryonic stem cells

artículo científico publicado en 2013

Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling

artículo científico publicado en 2016

Spry1 and spry2 are essential for development of the temporomandibular joint

artículo científico publicado en 2012

Stem Cell and Biomaterials Research in Dental Tissue Engineering and Regeneration ⬇️

artículo científico publicado el 1 de julio de 2012

Structural models of the bovine papillomavirus E5 protein

artículo científico publicado en 1998

The FaceBase Consortium: a comprehensive program to facilitate craniofacial research

artículo científico publicado en 2011

The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape.

artículo científico publicado en 2017

The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.

artículo científico publicado en 2013

The WNT10A gene in ectodermal dysplasias and selective tooth agenesis.

artículo científico publicado en 2014

The dynamics of supernumerary tooth development are differentially regulated by Sprouty genes.

artículo científico publicado en 2013

Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo

artículo científico publicado en 2015

Unraveling the molecular mechanisms that lead to supernumerary teeth in mice and men: current concepts and novel approaches

artículo científico publicado en 2007

microRNA miR-34a regulates cytodifferentiation and targets multi-signaling pathways in human dental papilla cells

artículo científico publicado en 2012

αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development

artículo científico publicado en 2016

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