Lista de obras - Massimo Locati - Dominio Público Uruguay

2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

artículo científico publicado en 2005

A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression

artículo científico publicado en 2001

ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity

artículo científico publicado en 2018

Aberrant CXCR4 Signaling at Crossroad of WHIM Syndrome and Waldenstrom's Macroglobulinemia

artículo científico publicado en 2020

Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14.

artículo científico publicado en 2009

Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages.

artículo científico publicado en 2007

Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls

artículo científico publicado en 2008

An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15.

artículo científico publicado en 2015

Anti-phospholipid antibody mediated fetal loss: still an open question from a pathogenic point of view

artículo científico publicado en 2010

Anti-phospholipid induced murine fetal loss: novel protective effect of a peptide targeting the β2 glycoprotein I phospholipid-binding site. Implications for human fetal loss.

artículo científico publicado en 2011

Atypical chemokine receptors: from silence to sound.

artículo científico

Chemoattractant receptors and leukocyte recruitment: more than cell migration.

artículo científico publicado en 2009

Chemokine decoy receptors: new players in reproductive immunology

scientific article published on January 2008

Chemokine receptors intracellular trafficking.

scientific article published on 06 May 2010

Chemokines and Cancer: A Fatal Attraction ⬇️

artículo científico publicado el 12 de abril de 2011

Chemokines and chemokine receptors: an overview.

scientific article published on January 2009

Chemokines as pharmacological targets

artículo científico publicado en 2008

Chemokines in immunopathology: From dark sides to clinical translation

Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors

artículo científico publicado en 2004

Chemokines: a superfamily of chemotactic cytokines.

artículo científico publicado en 1996

Control of murine Ly6Chigh monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6

artículo científico publicado en 2012

Convergent pathways of macrophage polarization: The role of B cells

artículo científico publicado en 2010

Correction: Convergent pathways of macrophage polarization: The role of B cells

D6 as a Decoy and Scavenger Receptor for Inflammatory CC Chemokines in the Skin

Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2

artículo científico publicado en 2007

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

artículo científico publicado en 2006

Differential regulation of iron homeostasis during human macrophage polarized activation

artículo científico publicado en 2010

Dissecting trafficking and signaling of atypical chemokine receptors.

artículo científico publicado en 2013

ERK-Dependent Downregulation of the Atypical Chemokine Receptor D6 Drives Tumor Aggressiveness in Kaposi Sarcoma

artículo científico publicado en 2014

Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway

scientific article published on 24 April 2019

Encapsulated mesenchymal stem cells for in vivo immunomodulation

artículo científico publicado en 2012

Epicardial fat thickness: relationship with plasma visfatin and plasminogen activator inhibitor-1 levels in visceral obesity.

artículo científico

Expression of chemokines and chemokine receptors in human colon cancer

artículo científico publicado en 2009

Expression of the atypical chemokine receptor D6 in human alveolar macrophages in COPD.

artículo científico publicado en 2013

Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.

artículo científico publicado en 2011

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.

artículo científico publicado en 2003

Flow cytometry applications for the analysis of chemokine receptor expression and function

artículo científico publicado en 2014

Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells

artículo científico publicado en 2004

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

artículo científico publicado en 2013

HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

artículo científico publicado en 1997

Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness.

artículo científico publicado en 2005

Housekeeping by chemokine scavenging

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes

artículo científico publicado en 2012

IL-8 induces a specific transcriptional profile in human neutrophils: synergism with LPS for IL-1 production

article

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease

artículo científico publicado en 2013

Impact of the anti-inflammatory agent bindarit on the chemokinome: selective inhibition of the monocyte chemotactic proteins

artículo científico publicado en 2008

Increased inflammation in mice deficient for the chemokine decoy receptor D6.

artículo científico publicado en 2005

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

artículo científico publicado en 2009

Inhibition of Monocyte Chemotaxis to C-C Chemokines by Antisense Oligonucleotide for Cytosolic Phospholipase A

artículo científico publicado en 1996

Interleukin 10 increases CCR5 expression and HIV infection in human monocytes

artículo científico publicado en 1998

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors

artículo científico publicado en 2013

Interplay of inflammation, immunity, and organ-specific adiposity with cardiovascular risk.

artículo científico publicado en 2014

Iron levels in polarized macrophages: regulation of immunity and autoimmunity.

artículo científico

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype ⬇️

artículo científico publicado el 21 de abril de 2011

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

scholarly article by Peter J. Murray et al published August 2014 in Immunity

Macrophage activation and polarization

artículo científico publicado en 2008

Macrophage activation and polarization as an adaptive component of innate immunity

artículo científico publicado en 2013

Macrophage activation and polarization: nomenclature and experimental guidelines

artículo científico publicado en 2014

Macrophage diversity and polarization in atherosclerosis: a question of balance

artículo científico publicado en 2009

Macrophage plasticity and polarization in tissue repair and remodelling

artículo científico publicado en 2012

Macrophage polarization comes of age.

artículo científico publicado en 2005

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

artículo científico publicado en 2002

Macrophages have a grip on the gut

artículo científico publicado en 2014

MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes

artículo científico publicado en 2015

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

artículo científico publicado en 2013

Never Underestimate the Power of a Neutrophil

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM

scientific article published on 03 April 2020

New nomenclature for atypical chemokine receptors

artículo científico publicado en 2014

New vistas on macrophage differentiation and activation

artículo científico publicado en 2007

Non-signaling chemokine receptors: mechanism of action and role in vivo.

artículo científico publicado en 2008

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

scholarly article

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia

artículo científico publicado en 2011

Orchestration of macrophage polarization

Phenotypic activation and pharmacological outcomes of spontaneously differentiated human monocyte-derived macrophages

artículo científico publicado en 2014

Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.

artículo científico publicado en 2010

Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways.

artículo científico publicado en 2015

Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.

artículo científico publicado en 2007

Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.

artículo científico publicado en 2012

Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence

artículo científico publicado en 2009

Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation

artículo científico publicado en 2008

Regulatory pathways in inflammation

artículo científico publicado en 2007

Review: Structure-function and biological properties of the atypical chemokine receptor D6.

artículo científico

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology

artículo científico publicado en 2011

Role of the chemokine decoy receptor D6 in balancing inflammation, immune activation, and antimicrobial resistance in Mycobacterium tuberculosis infection

artículo científico publicado en 2008

Role of the chemokine scavenger receptor D6 in balancing inflammation and immune activation

artículo científico publicado en 2009

Selective induction of phospholipase D1 in pathogen-activated human monocytes

artículo científico publicado en 2001

Selective modulation of protein kinase A I and II reveals distinct roles in thyroid cell gene expression and growth.

artículo científico publicado en 2006

Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages.

artículo científico publicado en 2012

Shaping and tuning of the chemokine system by regulation of receptor expression and signaling: dendritic cells as a paradigm.

artículo científico publicado en 2000

Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines

artículo científico publicado en 2005

Synergism Between Platelet Activating Factor and C-C Chemokines for Arachidonate Release in Human Monocytes

scientific article published on 01 March 1994

Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effects

artículo científico publicado en 2009

Synergy-inducing chemokines enhance CCR2 ligand activities on monocytes

artículo científico publicado en 2009

Systemic and cellular consequences of macrophage control of iron metabolism ⬇️

artículo científico publicado el 30 de enero de 2013

Targeting Chemokines in Cancer

Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief

artículo científico publicado en 2014

Targeting tumour-associated macrophages

artículo científico publicado en 2007

The Atypical Chemokine Receptor 2 Limits Progressive Fibrosis after Acute Ischemic Kidney Injury

artículo científico publicado en 2018

The Chemokine Decoy Receptor D6 Prevents Excessive Inflammation and Adverse Ventricular Remodeling After Myocardial Infarction

artículo científico publicado en 2012

The Italian Society of Immunology: past, present and future.

artículo científico publicado en 2010

The Yin Yang of Cancer Related Inflammation

article

The biochemistry and biology of the atypical chemokine receptors.

artículo científico

The chemoattractant decoy receptor D6 as a negative regulator of inflammatory responses

article

The chemokine system in cancer biology and therapy

scientific article published on 08 December 2009

The chemokine system: tuning and shaping by regulation of receptor expression and coupling in polarized responses.

artículo científico publicado en 2002

The lymphatic system controls intestinal inflammation and inflammation-associated colon cancer through the chemokine decoy receptor D6

artículo científico publicado en 2009

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis

scientific article published on 01 July 2019

The scavenging chemokine receptor ACKR2 has a significant impact on acute mortality rate and early lesion development after traumatic brain injury

artículo científico publicado en 2017

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

artículo científico publicado en 2009

Tumor-associated macrophages as a paradigm of macrophage plasticity, diversity, and polarization: lessons and open questions

artículo científico publicado en 2013

Tuning inflammation and immunity by chemokine sequestration: decoys and more

artículo científico publicado en 2006

Tuning of innate immunity and polarized responses by decoy receptors

artículo científico publicado en 2003

Understanding fibrosis pathogenesis via modeling macrophage-fibroblast interplay in immune-metabolic context

artículo científico publicado en 2022

beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6.

artículo científico publicado en 2004

β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6

artículo científico publicado en 2013

Lista de obras de Massimo Locati

2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.

A membrane-proximal basic domain and cysteine cluster in the C-terminal tail of CCR5 constitute a bipartite motif critical for cell surface expression

ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity

Aberrant CXCR4 Signaling at Crossroad of WHIM Syndrome and Waldenstrom's Macroglobulinemia

Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14.

Adenosine A2a receptor-mediated, normoxic induction of HIF-1 through PKC and PI-3K-dependent pathways in macrophages.

Allosteric inhibitors of chemoattractant receptors: opportunities and pitfalls

An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15.

Anti-phospholipid antibody mediated fetal loss: still an open question from a pathogenic point of view

Anti-phospholipid induced murine fetal loss: novel protective effect of a peptide targeting the β2 glycoprotein I phospholipid-binding site. Implications for human fetal loss.

Atypical chemokine receptors: from silence to sound.

Chemoattractant receptors and leukocyte recruitment: more than cell migration.

Chemokine decoy receptors: new players in reproductive immunology

Chemokine receptors intracellular trafficking.

Chemokines and Cancer: A Fatal Attraction ⬇️

Chemokines and chemokine receptors: an overview.

Chemokines as pharmacological targets

Chemokines in immunopathology: From dark sides to clinical translation

Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors

Chemokines: a superfamily of chemotactic cytokines.

Control of murine Ly6Chigh monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6

Convergent pathways of macrophage polarization: The role of B cells

Correction: Convergent pathways of macrophage polarization: The role of B cells

D6 as a Decoy and Scavenger Receptor for Inflammatory CC Chemokines in the Skin

Design of Noncompetitive Interleukin-8 Inhibitors Acting on CXCR1 and CXCR2

Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).

Differential regulation of iron homeostasis during human macrophage polarized activation

Dissecting trafficking and signaling of atypical chemokine receptors.

ERK-Dependent Downregulation of the Atypical Chemokine Receptor D6 Drives Tumor Aggressiveness in Kaposi Sarcoma

Effect of donepezil on the expression and responsiveness to LPS of CHRNA7 and CHRFAM7A in macrophages: A possible link to the cholinergic anti-inflammatory pathway

Encapsulated mesenchymal stem cells for in vivo immunomodulation

Epicardial fat thickness: relationship with plasma visfatin and plasminogen activator inhibitor-1 levels in visceral obesity.

Expression of chemokines and chemokine receptors in human colon cancer

Expression of the atypical chemokine receptor D6 in human alveolar macrophages in COPD.

Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.

Flow cytometry applications for the analysis of chemokine receptor expression and function

Gene expression profile activated by the chemokine CCL5/RANTES in human neuronal cells

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

HIV-1 coreceptor activity of CCR5 and its inhibition by chemokines: independence from G protein signaling and importance of coreceptor downmodulation.

Hepatocyte growth factor enhances CXCR4 expression favoring breast cancer cell invasiveness.

Housekeeping by chemokine scavenging

IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes

IL-8 induces a specific transcriptional profile in human neutrophils: synergism with LPS for IL-1 production

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease

Impact of the anti-inflammatory agent bindarit on the chemokinome: selective inhibition of the monocyte chemotactic proteins

Increased inflammation in mice deficient for the chemokine decoy receptor D6.

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

Inhibition of Monocyte Chemotaxis to C-C Chemokines by Antisense Oligonucleotide for Cytosolic Phospholipase A

Interleukin 10 increases CCR5 expression and HIV infection in human monocytes

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors

Interplay of inflammation, immunity, and organ-specific adiposity with cardiovascular risk.

Iron levels in polarized macrophages: regulation of immunity and autoimmunity.

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype ⬇️

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Macrophage activation and polarization

Macrophage activation and polarization as an adaptive component of innate immunity

Macrophage activation and polarization: nomenclature and experimental guidelines

Macrophage diversity and polarization in atherosclerosis: a question of balance

Macrophage plasticity and polarization in tissue repair and remodelling

Macrophage polarization comes of age.

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

Macrophages have a grip on the gut

MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes

Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b

Never Underestimate the Power of a Neutrophil

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM

New nomenclature for atypical chemokine receptors

New vistas on macrophage differentiation and activation

Non-signaling chemokine receptors: mechanism of action and role in vivo.

Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury.

Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia

Orchestration of macrophage polarization

Phenotypic activation and pharmacological outcomes of spontaneously differentiated human monocyte-derived macrophages

Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice.

Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways.

Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.

Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.

Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence