Lista de obras - Judy Hirst - Dominio Público Uruguay

A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase

artículo científico publicado en 2015

A scalable, GFP-based pipeline for membrane protein overexpression screening and purification

artículo científico publicado en 2005

A spectrophotometric coupled enzyme assay to measure the activity of succinate dehydrogenase

artículo científico publicado en 2013

A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex I

scientific article published on 12 June 2011

ATR-FTIR Redox Difference Spectroscopy ofYarrowia lipolyticaand Bovine Complex I†

scientific article published on 01 May 2006

An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis

artículo científico publicado en 2007

Analysis of the subunit composition of complex I from bovine heart mitochondria

artículo científico publicado en 2003

Antisymmetric exchange in [2Fe-2S]1+ clusters: EPR of the Rieske protein from Thermus thermophilus at pH 14.

artículo científico publicado en 2004

Architecture of mammalian respiratory complex I.

artículo científico publicado en 2014

Atomically defined mechanism for proton transfer to a buried redox centre in a protein

artículo científico publicado en 2000

Bovine complex I is a complex of 45 different subunits.

artículo científico publicado en 2006

Breaking and re-forming the disulfide bond at the high-potential, respiratory-type Rieske [2Fe-2S] center of thermus thermophilus: characterization of the sulfhydryl state by protein-film voltammetry

artículo científico publicado en 2002

Characterization of clinically identified mutations in NDUFV1, the flavin-binding subunit of respiratory complex I, using a yeast model system

artículo científico publicado en 2015

Comment on "Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry"

artículo científico publicado en 2019

Complete Thermodynamic Characterization of Reduction and Protonation of thebc1-type Rieske [2Fe-2S] Center ofThermus thermophilus

artículo científico publicado en 2001

Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex.

artículo científico publicado en 2021

Correction to “Reversible Interconversion of CO2 and Formate by a Molybdenum-Containing Formate Dehydrogenase”

artículo científico publicado en 2015

Correlating kinetic and structural data on ubiquinone binding and reduction by respiratory complex I.

artículo científico publicado en 2017

Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy

artículo científico publicado en 2022

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states ⬇️

artículo científico publicado en 2018

Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I

artículo científico publicado en 2022

Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.

artículo científico publicado en 2002

Deleting the IF1-like ζ subunit from Paracoccus denitrificans ATP synthase is not sufficient to activate ATP hydrolysis

artículo científico publicado en 2018

Detection and interpretation of redox potential optima in the catalytic activity of enzymes

artículo científico publicado en 2002

Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron-electron resonance

artículo científico publicado en 2010

Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy

artículo científico publicado en 2005

Effects of biguanides on oxidative phosphorylation

article published in 2014

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

artículo científico publicado en 2014

Electrocatalytic Voltammetry of Succinate Dehydrogenase: Direct Quantification of the Catalytic Properties of a Complex Electron-Transport Enzyme

artículo científico publicado en 1996

Elucidating the mechanisms of coupled electron transfer and catalytic reactions by protein film voltammetry

artículo científico publicado en 2006

Energy conversion, redox catalysis and generation of reactive oxygen species by respiratory complex I

artículo científico publicado en 2016

Erratum: Atomically defined mechanism for proton transfer to a buried redox centre in a protein

scientific article published in Nature

Exploring interactions between the 49 kDa and ND1 subunits in mitochondrial NADH-ubiquinone oxidoreductase (complex I) by photoaffinity labeling

artículo científico publicado en 2011

Fast voltammetric studies of the kinetics and energetics of coupled electron-transfer reactions in proteins

artículo científico publicado en 2000

Fast-scan cyclic voltammetry of protein films on pyrolytic graphite edge electrodes: characteristics of electron exchange

artículo científico publicado en 1998

Formation and characterization of an all-ferrous Rieske cluster and stabilization of the [2Fe-2S]0 core by protonation

scholarly article

Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects

artículo científico publicado en 2017

GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)

artículo científico publicado en 2001

Global Observation of Hydrogen/Deuterium Isotope Effects on Bidirectional Catalytic Electron Transport in an Enzyme: Direct Measurement by Protein-Film Voltammetry

artículo científico publicado en 1997

High-resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: analysis and comparison

artículo científico publicado en 2003

Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells

scientific article published on 27 May 2020

Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

artículo científico publicado en 2007

Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria

artículo científico publicado en 2006

Interpreting the Catalytic Voltammetry of Electroactive Enzymes Adsorbed on Electrodes

Interpreting the catalytic voltammetry of an adsorbed enzyme by considering substrate mass transfer, enzyme turnover, and interfacial electron transport

artículo científico publicado en 2006

Investigating the function of [2Fe-2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential

artículo científico publicado en 2013

Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides

artículo científico publicado en 2013

Investigation of the mechanism of proton translocation by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria: does the enzyme operate by a Q-cycle mechanism?

artículo científico publicado en 2006

Kinetic evidence against partitioning of the ubiquinone pool and the catalytic relevance of respiratory-chain supercomplexes.

artículo científico publicado en 2014

Kinetics and Mechanism of Redox-Coupled, Long-Range Proton Transfer in an Iron−Sulfur Protein. Investigation by Fast-Scan Protein-Film Voltammetry

scientific article published in 1998

Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I

artículo científico publicado en 2003

Mechanistic Study of Photoelectrochemical Reactions: Phototransient Experiments

article

Mitochondrial Complex I ⬇️

artículo científico publicado el 18 de marzo de 2013

Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling

scholarly article by Justin G Fedor published in September 2018

Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation

artículo científico publicado en 2020

Modelling electrode reactions using the strongly implicit procedure

Modulation of heme redox potential in the cytochrome c6 family

artículo científico publicado en 2007

Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase

artículo científico publicado en 2016

Mössbauer spectroscopy on respiratory complex I: the iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized

artículo científico publicado en 2011

Off-pathway, oxygen-dependent thiamine radical in the Krebs cycle.

artículo científico publicado en 2008

Open questions: respiratory chain supercomplexes-why are they there and what do they do?

artículo científico publicado en 2018

Oxidation-State-Dependent Binding Properties of the Active Site in a Mo-Containing Formate Dehydrogenase.

artículo científico publicado en 2017

Photoelectrochemical reduction of meta-halonitrobenzenes and related species

Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria

artículo científico publicado en 2008

Reaction of complex metalloproteins studied by protein-film voltammetry

Reactions of the flavin mononucleotide in complex I: a combined mechanism describes NADH oxidation coupled to the reduction of APAD+, ferricyanide, or molecular oxygen

artículo científico publicado en 2009

Redox properties of the [2Fe-2S] center in the 24 kDa (NQO2) subunit of NADH:ubiquinone oxidoreductase (complex I).

artículo científico publicado en 2002

Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species

artículo científico publicado en 2009

Reduction of the iron-sulfur clusters in mitochondrial NADH:ubiquinone oxidoreductase (complex I) by EuII-DTPA, a very low potential reductant

artículo científico publicado en 2008

Reduction potentials of Rieske clusters: importance of the coupling between oxidation state and histidine protonation state

artículo científico publicado en 2003

Reevaluating the relationship between EPR spectra and enzyme structure for the iron sulfur clusters in NADH:quinone oxidoreductase

artículo científico publicado en 2007

Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure

artículo científico publicado en 2001

Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 2. Effects on heme coordination and function

artículo científico publicado en 2001

Respiratory Complex I in Bos taurus and Paracoccus denitrificans Pumps Four Protons across the Membrane for Every NADH Oxidized.

artículo científico publicado en 2017

Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes

artículo científico publicado en 2011

Reversible and Selective Interconversion of Hydrogen and Carbon Dioxide into Formate by a Semiartificial Formate Hydrogenlyase Mimic

artículo científico publicado en 2019

Reversible glutathionylation of complex I increases mitochondrial superoxide formation

artículo científico publicado en 2003

Reversible interconversion of CO2 and formate by a molybdenum-containing formate dehydrogenase

artículo científico publicado en 2014

Reversible interconversion of carbon dioxide and formate by an electroactive enzyme

artículo científico publicado en 2008

Reversible, electrochemical interconversion of NADH and NAD+ by the catalytic (Ilambda) subcomplex of mitochondrial NADH:ubiquinone oxidoreductase (complex I).

artículo científico publicado en 2003

Roles of the disulfide bond and adjacent residues in determining the reduction potentials and stabilities of respiratory-type Rieske clusters

artículo científico publicado en 2005

Small-volume potentiometric titrations: EPR investigations of Fe-S cluster N2 in mitochondrial complex I.

artículo científico publicado en 2016

Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides

artículo científico publicado en 2023

Structure of inhibitor-bound mammalian complex I

artículo científico publicado en 2020

Structure of mammalian respiratory complex I

artículo científico publicado en 2016

Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments

artículo científico publicado en 2015

Structure of the Deactive State of Mammalian Respiratory Complex I.

artículo científico publicado en 2018

Structure of the deactive state of mammalian respiratory complex I

Subunit NDUFV3 is present in two distinct isoforms in mammalian complex I.

artículo científico publicado en 2016

Superoxide is produced by the reduced flavin in mitochondrial complex I: a single, unified mechanism that applies during both forward and reverse electron transfer

artículo científico publicado en 2011

The Enigma of the Respiratory Chain Supercomplex

artículo científico publicado en 2017

The Inhibition of Mitochondrial Complex I (NADH:Ubiquinone Oxidoreductase) by Zn2+

artículo científico publicado en 2006

The deactive form of respiratory complex I from mammalian mitochondria is a Na+/H+ antiporter

artículo científico publicado en 2012

The dichotomy of complex I: a sodium ion pump or a proton pump

artículo científico publicado en 2003

The flavoprotein subcomplex of complex I (NADH:ubiquinone oxidoreductase) from bovine heart mitochondria: insights into the mechanisms of NADH oxidation and NAD+ reduction from protein film voltammetry

artículo científico publicado en 2007

The mechanism of catalysis by type-II NADH:quinone oxidoreductases.

artículo científico publicado en 2017

The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria

artículo científico publicado en 2006

The mitochondrial-encoded subunits of respiratory complex I (NADH:ubiquinone oxidoreductase): identifying residues important in mechanism and disease

artículo científico publicado en 2011

The nuclear encoded subunits of complex I from bovine heart mitochondria

artículo científico publicado en 2003

The post-translational modifications of the nuclear encoded subunits of complex I from bovine heart mitochondria.

artículo científico publicado en 2005

The production of reactive oxygen species by complex I.

artículo científico publicado en 2008

The respiratory complexes I from the mitochondria of two Pichia species

artículo científico publicado en 2009

The subunit composition of mitochondrial NADH:ubiquinone oxidoreductase (complex I) from Pichia pastoris

artículo científico publicado en 2010

Towards the molecular mechanism of respiratory complex I.

artículo científico publicado en 2009

Transhydrogenation reactions catalyzed by mitochondrial NADH-ubiquinone oxidoreductase (Complex I).

artículo científico publicado en 2007

Truncation of subunit ND2 disrupts the threefold symmetry of the antiporter-like subunits in complex I from higher metazoans

artículo científico publicado en 2010

Unusual oxidative chemistry of N(omega)-hydroxyarginine and N-hydroxyguanidine catalyzed at an engineered cavity in a heme peroxidase

artículo científico publicado en 2000

Using Hyperfine Electron Paramagnetic Resonance Spectroscopy to Define the Proton-Coupled Electron Transfer Reaction at Fe-S Cluster N2 in Respiratory Complex I.

artículo científico publicado en 2017

Very Rapid, Cooperative Two-Electron/Two-Proton Redox Reactions of [3Fe−4S] Clusters: Detection and Analysis by Protein-Film Voltammetry

artículo científico publicado en 1998

Voltammetric studies of bidirectional catalytic electron transport in Escherichia coli succinate dehydrogenase: comparison with the enzyme from beef heart mitochondria

artículo científico publicado en 1999

Lista de obras de Judy Hirst

A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase

A scalable, GFP-based pipeline for membrane protein overexpression screening and purification

A spectrophotometric coupled enzyme assay to measure the activity of succinate dehydrogenase

A ternary mechanism for NADH oxidation by positively charged electron acceptors, catalyzed at the flavin site in respiratory complex I

ATR-FTIR Redox Difference Spectroscopy ofYarrowia lipolyticaand Bovine Complex I†

An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis

Analysis of the subunit composition of complex I from bovine heart mitochondria

Antisymmetric exchange in [2Fe-2S]1+ clusters: EPR of the Rieske protein from Thermus thermophilus at pH 14.

Architecture of mammalian respiratory complex I.

Atomically defined mechanism for proton transfer to a buried redox centre in a protein

Bovine complex I is a complex of 45 different subunits.

Breaking and re-forming the disulfide bond at the high-potential, respiratory-type Rieske [2Fe-2S] center of thermus thermophilus: characterization of the sulfhydryl state by protein-film voltammetry

Characterization of clinically identified mutations in NDUFV1, the flavin-binding subunit of respiratory complex I, using a yeast model system

Comment on "Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry"

Complete Thermodynamic Characterization of Reduction and Protonation of thebc1-type Rieske [2Fe-2S] Center ofThermus thermophilus

Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex.

Correction to “Reversible Interconversion of CO2 and Formate by a Molybdenum-Containing Formate Dehydrogenase”

Correlating kinetic and structural data on ubiquinone binding and reduction by respiratory complex I.

Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy

Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states ⬇️

Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I

Definition of the nuclear encoded protein composition of bovine heart mitochondrial complex I. Identification of two new subunits.

Deleting the IF1-like ζ subunit from Paracoccus denitrificans ATP synthase is not sufficient to activate ATP hydrolysis

Detection and interpretation of redox potential optima in the catalytic activity of enzymes

Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron-electron resonance

Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy

Effects of biguanides on oxidative phosphorylation

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria

Electrocatalytic Voltammetry of Succinate Dehydrogenase: Direct Quantification of the Catalytic Properties of a Complex Electron-Transport Enzyme

Elucidating the mechanisms of coupled electron transfer and catalytic reactions by protein film voltammetry

Energy conversion, redox catalysis and generation of reactive oxygen species by respiratory complex I

Erratum: Atomically defined mechanism for proton transfer to a buried redox centre in a protein

Exploring interactions between the 49 kDa and ND1 subunits in mitochondrial NADH-ubiquinone oxidoreductase (complex I) by photoaffinity labeling

Fast voltammetric studies of the kinetics and energetics of coupled electron-transfer reactions in proteins

Fast-scan cyclic voltammetry of protein films on pyrolytic graphite edge electrodes: characteristics of electron exchange

Formation and characterization of an all-ferrous Rieske cluster and stabilization of the [2Fe-2S]0 core by protonation

Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects

GRIM-19, a cell death regulatory gene product, is a subunit of bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I)

Global Observation of Hydrogen/Deuterium Isotope Effects on Bidirectional Catalytic Electron Transport in an Enzyme: Direct Measurement by Protein-Film Voltammetry

High-resolution structure of the soluble, respiratory-type Rieske protein from Thermus thermophilus: analysis and comparison

Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells

Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases

Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria

Interpreting the Catalytic Voltammetry of Electroactive Enzymes Adsorbed on Electrodes

Interpreting the catalytic voltammetry of an adsorbed enzyme by considering substrate mass transfer, enzyme turnover, and interfacial electron transport

Investigating the function of [2Fe-2S] cluster N1a, the off-pathway cluster in complex I, by manipulating its reduction potential

Investigation of NADH binding, hydride transfer, and NAD(+) dissociation during NADH oxidation by mitochondrial complex I using modified nicotinamide nucleotides

Investigation of the mechanism of proton translocation by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria: does the enzyme operate by a Q-cycle mechanism?

Kinetic evidence against partitioning of the ubiquinone pool and the catalytic relevance of respiratory-chain supercomplexes.

Kinetics and Mechanism of Redox-Coupled, Long-Range Proton Transfer in an Iron−Sulfur Protein. Investigation by Fast-Scan Protein-Film Voltammetry

Mechanisms of redox-coupled proton transfer in proteins: role of the proximal proline in reactions of the [3Fe-4S] cluster in Azotobacter vinelandii ferredoxin I

Mechanistic Study of Photoelectrochemical Reactions: Phototransient Experiments

Mitochondrial Complex I ⬇️

Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling

Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation

Modelling electrode reactions using the strongly implicit procedure

Modulation of heme redox potential in the cytochrome c6 family

Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase

Mössbauer spectroscopy on respiratory complex I: the iron-sulfur cluster ensemble in the NADH-reduced enzyme is partially oxidized

Off-pathway, oxygen-dependent thiamine radical in the Krebs cycle.

Open questions: respiratory chain supercomplexes-why are they there and what do they do?

Oxidation-State-Dependent Binding Properties of the Active Site in a Mo-Containing Formate Dehydrogenase.

Photoelectrochemical reduction of meta-halonitrobenzenes and related species

Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria

Reaction of complex metalloproteins studied by protein-film voltammetry

Reactions of the flavin mononucleotide in complex I: a combined mechanism describes NADH oxidation coupled to the reduction of APAD+, ferricyanide, or molecular oxygen

Redox properties of the [2Fe-2S] center in the 24 kDa (NQO2) subunit of NADH:ubiquinone oxidoreductase (complex I).

Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species

Reduction of the iron-sulfur clusters in mitochondrial NADH:ubiquinone oxidoreductase (complex I) by EuII-DTPA, a very low potential reductant

Reduction potentials of Rieske clusters: importance of the coupling between oxidation state and histidine protonation state

Reevaluating the relationship between EPR spectra and enzyme structure for the iron sulfur clusters in NADH:quinone oxidoreductase

Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 1. Effects on structure

Replacement of the axial histidine ligand with imidazole in cytochrome c peroxidase. 2. Effects on heme coordination and function

Respiratory Complex I in Bos taurus and Paracoccus denitrificans Pumps Four Protons across the Membrane for Every NADH Oxidized.

Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes

Reversible and Selective Interconversion of Hydrogen and Carbon Dioxide into Formate by a Semiartificial Formate Hydrogenlyase Mimic

Reversible glutathionylation of complex I increases mitochondrial superoxide formation

Reversible interconversion of CO2 and formate by a molybdenum-containing formate dehydrogenase

Reversible interconversion of carbon dioxide and formate by an electroactive enzyme