Lista de obras - Johan P Turkenburg - Dominio Público Uruguay

A covalent succinylcysteine-like intermediate in the enzyme-catalyzed transformation of maleate to fumarate by maleate isomerase

artículo científico publicado en 2010

A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor

artículo científico publicado en 2012

Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules

artículo científico publicado en 2004

Activity, stability and 3-D structure of the Cu(ii) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens ⬇️

artículo científico publicado en 2016

Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool

artículo científico publicado en 2014

B-DNA at atomic resolution reveals extended hydration patterns

artículo científico publicado en 1999

Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

artículo científico publicado en 2016

CCP4i2: the new graphical user interface to the CCP4 program suite.

artículo científico publicado en 2018

Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold

artículo científico publicado en 2002

Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12

artículo científico publicado en 2007

Characterization of a novel pectate lyase, Pel10A, from Pseudomonas cellulosa

artículo científico publicado en 2001

Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules

artículo científico publicado en 2010

Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants

artículo científico publicado en 2004

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

artículo científico publicado en 2017

Convergent evolution sheds light on the anti-beta -elimination mechanism common to family 1 and 10 polysaccharide lyases

artículo científico publicado en 2002

Crystal and Solution Studies Reveal That the Transcriptional Regulator AcnR of Corynebacterium glutamicum Is Regulated by Citrate-Mg2+ Binding to a Non-canonical Pocket

artículo científico publicado en 2013

Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein

artículo científico publicado en 2008

Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4

artículo científico publicado en 1994

Crystal structure of the putative peptide-binding protein AppA from Clostridium difficile

artículo científico publicado en 2019

Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations

artículo científico publicado en 2011

Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains

artículo científico publicado en 2008

Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile

artículo científico publicado en 2020

Crystallization and preliminary crystallographic investigation of a low-pH native insulin monomer with flexible behaviour.

artículo científico publicado en 2001

Degradation of Phytate by the 6-Phytase from Hafnia alvei: A Combined Structural and Solution Study

artículo científico publicado en 2013

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

artículo científico publicado en 2008

Evidence for Steric Regulation of Fibrinogen Binding to Staphylococcus aureus Fibronectin-binding Protein A (FnBPA)

artículo científico publicado en 2014

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

artículo científico publicado en 2009

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring

artículo científico publicado en 2009

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

artículo científico publicado en 2006

Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.

artículo científico publicado en 2014

I222 crystal form of despentapeptide (B26-B30) insulin provides new insights into the properties of monomeric insulin

artículo científico publicado en 2006

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

artículo científico publicado en 2010

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

artículo científico publicado en 2014

Insights into the Structural Determinants of Cohesin—Dockerin Specificity Revealed by the Crystal Structure of the Type II Cohesin from Clostridium thermocellum SdbA

artículo científico publicado en 2005

Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA

artículo científico publicado en 2002

Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM4- siderophore analogues of varied linker length

artículo científico publicado en 2017

Modern developments in molecular replacement.

artículo científico publicado en 1996

Molecular recognition in insulin assembly.

artículo científico publicado en 1993

Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution

artículo científico publicado en 2003

Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

artículo científico publicado en 2011

Purification, crystallization and preliminary X-ray diffraction analysis of the Trichoderma reesei hydrophobin HFBI.

artículo científico publicado en 2004

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

artículo científico publicado en 2016

Refinement of Haemophilus influenzae diaminopimelic acid epimerase (DapF) at 1.75 A resolution suggests a mechanism for stereocontrol during catalysis

artículo científico publicado en 2004

Staphylococcal biofilm-forming protein has a contiguous rod-like structure

artículo científico publicado en 2012

Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

artículo científico publicado en 2013

Structural analysis of a chimeric bacterial alpha-amylase. High-resolution analysis of native and ligand complexes

artículo científico publicado en 2000

Structural and Functional Analysis of the Tandem -Zipper Interaction of a Streptococcal Protein with Human Fibronectin

artículo científico publicado en 2011

Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance

scientific article published on 03 October 2019

Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans

artículo científico publicado en 2015

Structural and functional insights into asymmetric enzymatic dehydration of alkenols.

artículo científico publicado en 2017

Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum

artículo científico publicado en 2006

Structural origins of the functional divergence of human insulin-like growth factor-I and insulin

artículo científico publicado en 2002

Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase

artículo científico publicado en 2000

Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate

artículo científico publicado en 2013

Structure and activity of the Streptococcus pyogenes family GH1 6-phospho-β-glucosidase SPy1599

artículo científico publicado en 2013

Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases.

artículo científico publicado en 2006

Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae ⬇️

artículo científico publicado en 2018

Structure and interactions of theBacillus subtilissporulation inhibitor of DNA replication, SirA, with domain I of DnaA

artículo científico publicado en 2014

Structure of a Cys25-->Ser mutant of human cathepsin S

artículo científico publicado en 2002

Structure of a GH51 α-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi

scientific article published on 16 October 2020

Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix

artículo científico publicado en 2005

Structure of a pullulanase from Bacillus acidopullulyticus

artículo científico publicado en 2009

Structure of the GH76 α-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron

artículo científico publicado en 2015

Structure of the virulence-associated protein VapD from the intracellular pathogenRhodococcus equi

artículo científico publicado en 2014

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline

artículo científico publicado en 2015

Structures of a γ-aminobutyrate (GABA) transaminase from thes-triazine-degrading organismArthrobacter aurescensTC1 in complex with PLP and with its external aldimine PLP–GABA adduct

artículo científico publicado en 2012

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

artículo científico publicado en 2018

Structures of the Apo and FAD-bound forms of 2-hydroxybiphenyl 3-monooxygenase (HbpA) locate activity hotspots identified by using directed evolution

artículo científico publicado en 2015

Structures of two truncated phage-tail hyaluronate lyases fromStreptococcus pyogenesserotype M1

artículo científico publicado en 2009

Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A.

artículo científico publicado en 2005

The 1.5-Å Structure of XplA-heme, an Unusual Cytochrome P450 Heme Domain That Catalyzes Reductive Biotransformation of Royal Demolition Explosive

artículo científico publicado en 2009

The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily

artículo científico publicado en 2003

The Copper Active Site of CBM33 Polysaccharide Oxygenases ⬇️

artículo científico publicado en 2013

The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: structure and biochemistry of the Clostridium thermocellum X6b domain

artículo científico publicado en 2000

The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold

artículo científico publicado en 2004

The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration

artículo científico publicado en 2009

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity

artículo científico publicado en 2007

The mechanisms by which family 10 glycoside hydrolases bind decorated substrates

artículo científico publicado en 2004

The structural characterization of a prophage-encoded extracellular DNase from Streptococcus pyogenes

artículo científico publicado en 2012

The structure of a family GH25 lysozyme fromAspergillus fumigatus

artículo científico publicado en 2010

The structure of monoamine oxidase from Aspergillus niger provides a molecular context for improvements in activity obtained by directed evolution

artículo científico publicado en 2008

Thermodynamic and structural investigation of the specific SDS binding ofhumicola insolenscutinase

artículo científico publicado en 2014

Three-dimensional structure of aStreptomyces sviceusGNAT acetyltransferase with similarity to the C-terminal domain of the human GH84O-GlcNAcase

artículo científico publicado en 2014

Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases

artículo científico publicado en 2016

Tying down the arm in Bacillus dUTPase: structure and mechanism

artículo científico publicado en 2013

Water Networks Can Determine the Affinity of Ligand Binding to Proteins

scientific article published on 26 September 2019

dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors.

artículo científico publicado en 2005

Lista de obras de Johan P Turkenburg

A covalent succinylcysteine-like intermediate in the enzyme-catalyzed transformation of maleate to fumarate by maleate isomerase

A flavoprotein monooxygenase that catalyses a Baeyer-Villiger reaction and thioether oxidation using NADH as the nicotinamide cofactor

Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules

Activity, stability and 3-D structure of the Cu(ii) form of a chitin-active lytic polysaccharide monooxygenase from Bacillus amyloliquefaciens ⬇️

Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: a powerful quality-control tool

B-DNA at atomic resolution reveals extended hydration patterns

Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

CCP4i2: the new graphical user interface to the CCP4 program suite.

Cellvibrio japonicus alpha-L-arabinanase 43A has a novel five-blade beta-propeller fold

Characterization and three-dimensional structures of two distinct bacterial xyloglucanases from families GH5 and GH12

Characterization of a novel pectate lyase, Pel10A, from Pseudomonas cellulosa

Circular Permutation Provides an Evolutionary Link between Two Families of Calcium-dependent Carbohydrate Binding Modules

Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

Convergent evolution sheds light on the anti-beta -elimination mechanism common to family 1 and 10 polysaccharide lyases

Crystal and Solution Studies Reveal That the Transcriptional Regulator AcnR of Corynebacterium glutamicum Is Regulated by Citrate-Mg2+ Binding to a Non-canonical Pocket

Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured protein

Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4

Crystal structure of the putative peptide-binding protein AppA from Clostridium difficile

Crystal structures of a family 8 polysaccharide lyase reveal open and highly occluded substrate-binding cleft conformations

Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains

Crystal structures of the GH18 domain of the bifunctional peroxiredoxin-chitinase CotE from Clostridium difficile

Crystallization and preliminary crystallographic investigation of a low-pH native insulin monomer with flexible behaviour.

Degradation of Phytate by the 6-Phytase from Hafnia alvei: A Combined Structural and Solution Study

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

Evidence for Steric Regulation of Fibrinogen Binding to Staphylococcus aureus Fibronectin-binding Protein A (FnBPA)

Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline.

Human insulin analogues modified at the B26 site reveal a hormone conformation that is undetected in the receptor complex.

I222 crystal form of despentapeptide (B26-B30) insulin provides new insights into the properties of monomeric insulin

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues

Insight into the Structural and Biological Relevance of the T/R Transition of the N-Terminus of the B-Chain in Human Insulin

Insights into the Structural Determinants of Cohesin—Dockerin Specificity Revealed by the Crystal Structure of the Type II Cohesin from Clostridium thermocellum SdbA

Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA

Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM4- siderophore analogues of varied linker length

Modern developments in molecular replacement.

Molecular recognition in insulin assembly.

Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution

Non-equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface

Purification, crystallization and preliminary X-ray diffraction analysis of the Trichoderma reesei hydrophobin HFBI.

Rational steering of insulin binding specificity by intra-chain chemical crosslinking

Refinement of Haemophilus influenzae diaminopimelic acid epimerase (DapF) at 1.75 A resolution suggests a mechanism for stereocontrol during catalysis

Staphylococcal biofilm-forming protein has a contiguous rod-like structure

Structural Integrity of the B24 Site in Human Insulin Is Important for Hormone Functionality

Structural analysis of a chimeric bacterial alpha-amylase. High-resolution analysis of native and ligand complexes

Structural and Functional Analysis of the Tandem -Zipper Interaction of a Streptococcal Protein with Human Fibronectin

Structural and Functional Characterization of Three Novel Fungal Amylases with Enhanced Stability and pH Tolerance

Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans

Structural and functional insights into asymmetric enzymatic dehydration of alkenols.

Structural insight into the ligand specificity of a thermostable family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum

Structural origins of the functional divergence of human insulin-like growth factor-I and insulin

Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase

Structure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrate

Structure and activity of the Streptococcus pyogenes family GH1 6-phospho-β-glucosidase SPy1599

Structure and activity of two metal ion-dependent acetylxylan esterases involved in plant cell wall degradation reveals a close similarity to peptidoglycan deacetylases.

Structure and function of a glycoside hydrolase family 8 endoxylanase from Teredinibacter turnerae ⬇️

Structure and interactions of theBacillus subtilissporulation inhibitor of DNA replication, SirA, with domain I of DnaA

Structure of a Cys25-->Ser mutant of human cathepsin S

Structure of a GH51 α-L-arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi

Structure of a group A streptococcal phage-encoded virulence factor reveals a catalytically active triple-stranded beta-helix

Structure of a pullulanase from Bacillus acidopullulyticus

Structure of the GH76 α-mannanase homolog, BT2949, from the gut symbiont Bacteroides thetaiotaomicron

Structure of the virulence-associated protein VapD from the intracellular pathogenRhodococcus equi

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline

Structures of a γ-aminobutyrate (GABA) transaminase from thes-triazine-degrading organismArthrobacter aurescensTC1 in complex with PLP and with its external aldimine PLP–GABA adduct

Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones

Structures of the Apo and FAD-bound forms of 2-hydroxybiphenyl 3-monooxygenase (HbpA) locate activity hotspots identified by using directed evolution

Structures of two truncated phage-tail hyaluronate lyases fromStreptococcus pyogenesserotype M1

Tailored catalysts for plant cell-wall degradation: redesigning the exo/endo preference of Cellvibrio japonicus arabinanase 43A.

The 1.5-Å Structure of XplA-heme, an Unusual Cytochrome P450 Heme Domain That Catalyzes Reductive Biotransformation of Royal Demolition Explosive

The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily

The Copper Active Site of CBM33 Polysaccharide Oxygenases ⬇️

The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: structure and biochemistry of the Clostridium thermocellum X6b domain

The crystal structure of Trypanosoma cruzi dUTPase reveals a novel dUTP/dUDP binding fold

The crystal structure of a family GH25 lysozyme from Bacillus anthracis implies a neighboring-group catalytic mechanism with retention of anomeric configuration

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity

The mechanisms by which family 10 glycoside hydrolases bind decorated substrates

The structural characterization of a prophage-encoded extracellular DNase from Streptococcus pyogenes