Lista de obras - Dmitry B Veprintsev - Dominio Público Uruguay

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

artículo científico publicado en 2008

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

artículo científico publicado en 2017

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

artículo científico publicado en 2002

A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins

scientific article published on 01 October 2019

AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.

artículo científico publicado en 2013

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

artículo científico publicado en 2011

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

artículo científico publicado en 2008

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid

artículo científico publicado en 2012

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

artículo científico publicado en 2016

Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis

artículo científico publicado en 2012

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

artículo científico publicado en 2005

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

artículo científico publicado en 2004

Binding of natively unfolded HIF-1alpha ODD domain to p53

scientific journal article

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

artículo científico publicado en 2002

Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.

artículo científico publicado en 2018

Comparative binding of p53 to its promoter and DNA recognition elements

artículo científico publicado en 2005

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

artículo científico publicado en 2004

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

artículo científico publicado en 2009

Cooperative binding of tetrameric p53 to DNA.

artículo científico publicado en 2004

Cooperative thermal transitions of bovine and human apo-α-lactalbumins: evidence for a new intermediate state

article

Core domain interactions in full-length p53 in solution

artículo científico publicado en 2006

Correction: Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis.

artículo científico publicado en 2013

Corrigendum to “The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger” [J. Mol. Biol. 407 (2011) 149–170].

artículo científico publicado en 2012

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

artículo científico publicado en 2004

Crystal structure of the ENT domain of human EMSY.

artículo científico publicado en 2005

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

artículo científico publicado en 2014

Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter

artículo científico publicado en 2010

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

scientific article published on 19 March 2019

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

artículo científico publicado en 2016

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

artículo científico publicado en 2006

Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.

artículo científico publicado en 2008

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

artículo científico publicado en 2006

Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA

artículo científico publicado en 2010

End binding proteins are obligatory dimers

artículo científico publicado en 2013

Features critical for membrane binding revealed by DivIVA crystal structure

artículo científico publicado en 2010

Fine tuning the N-terminus of a calcium binding protein: alpha-lactalbumin

artículo científico publicado en 1999

Fine tuning the N‐terminus of a calcium binding protein: α‐lactalbumin

scholarly article by Dmitry B. Veprintsev published in October 1999

High-throughput Site-directed Scanning Mutagenesis Using a Two-fragment PCR Approach

publication published on 05 January 2020

High-throughput mutagenesis using a two-fragment PCR approach

artículo científico publicado en 2017

Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

artículo científico publicado en 2014

Human full-length Securin is a natively unfolded protein

artículo científico publicado en 2005

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

artículo científico publicado en 2007

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

artículo científico publicado en 2013

Insights into the Basal Activity and Activation Mechanism of the β1 Adrenergic Receptor Using Native Mass Spectrometry

artículo científico publicado en 2018

Interactions of alpha-lactalbumins with lipid vesicles studied by tryptophan fluorescence.

artículo científico publicado en 1996

Kinetic Instability of p53 Core Domain Mutants

artículo científico publicado en 2003

Large-scale production and protein engineering of G protein-coupled receptors for structural studies

artículo científico publicado en 2015

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

artículo científico publicado en 2020

Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography

artículo científico publicado en 2001

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.

artículo científico publicado en 2012

Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists

artículo científico publicado en 2024

Modulation of binding of DNA to the C-terminal domain of p53 by acetylation

artículo científico publicado en 2005

Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers

artículo científico publicado en 2009

Molecular basis for modulation of the p53 target selectivity by KLF4.

artículo científico publicado en 2012

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.

artículo científico publicado en 2010

Mutating aspartate in the calcium-binding site of alpha-lactalbumin: effects on the protein stability and cation binding

artículo científico publicado en 2001

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

artículo científico publicado en 2018

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

artículo científico publicado en 2009

Pb2+ and Hg2+ binding to alpha-lactalbumin

artículo científico publicado en 1996

Probing Gαi1 protein activation at single-amino acid resolution.

artículo científico publicado en 2015

Production and purification of human Hsp90β in Escherichia coli

artículo científico publicado en 2017

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

artículo científico publicado en 2005

Recognition of DNA by p53 Core Domain and Location of Intermolecular Contacts of Cooperative Binding

artículo científico publicado en 2002

Regulation of DNA binding of p53 by its C-terminal domain

artículo científico publicado en 2004

Sequence determinants of a microtubule tip localization signal (MtLS).

artículo científico publicado en 2012

Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins

artículo científico publicado en 2012

Stability of p53 homologs

artículo científico publicado en 2012

Stabilization of G protein-coupled receptors by point mutations

artículo científico publicado en 2015

Structural and mutational analysis of the cell division protein FtsQ

artículo científico publicado en 2008

Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus

artículo científico publicado en 2003

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

artículo científico publicado en 2009

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

artículo científico publicado en 2007

Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

artículo científico publicado en 2004

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

artículo científico publicado en 2007

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

artículo científico publicado en 2008

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

artículo científico publicado en 2014

Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase

artículo científico publicado en 2004

Structures of SAS-6 suggest its organization in centrioles

artículo científico publicado en 2011

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

artículo científico publicado en 2005

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

artículo científico publicado en 2011

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

artículo científico publicado en 2008

The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger

artículo científico publicado en 2011

The central region of HDM2 provides a second binding site for p53.

artículo científico publicado en 2006

The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site

artículo científico publicado en 2008

The structure and interactions of the proline-rich domain of ASPP2

artículo científico publicado en 2008

The structure of the AXH domain of spinocerebellar ataxin-1

artículo científico publicado en 2004

Universal allosteric mechanism for Gα activation by GPCRs

artículo científico publicado en 2015

Zinc binding in bovine alpha-lactalbumin: sequence homology may not be a predictor of subtle functional features

scientific article published on 01 July 2000

Zinc binding in bovine α‐lactalbumin: Sequence homology may not be a predictor of subtle functional features

scholarly article by Serge E. Permyakov published in July 2000

pH-induced transition and Zn2+ -binding properties of bovine prolactin 1

artículo científico publicado en 1997

Lista de obras de Dmitry B Veprintsev

14-3-3 activation of DNA binding of p53 by enhancing its association into tetramers

A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins

AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid

Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor

Bin2 is a membrane sculpting N-BAR protein that influences leucocyte podosomes, motility and phagocytosis

Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

Binding of natively unfolded HIF-1alpha ODD domain to p53

CRINEPT-TROSY NMR reveals p53 core domain bound in an unfolded form to the chaperone Hsp90.

Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms.

Comparative binding of p53 to its promoter and DNA recognition elements

Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis

Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

Cooperative binding of tetrameric p53 to DNA.

Cooperative thermal transitions of bovine and human apo-α-lactalbumins: evidence for a new intermediate state

Core domain interactions in full-length p53 in solution

Correction: Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis.

Corrigendum to “The DNA-Binding Domain of Human PARP-1 Interacts with DNA Single-Strand Breaks as a Monomer through Its Second Zinc Finger” [J. Mol. Biol. 407 (2011) 149–170].

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

Crystal structure of the ENT domain of human EMSY.

Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein

Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.

Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).

Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA

End binding proteins are obligatory dimers

Features critical for membrane binding revealed by DivIVA crystal structure

Fine tuning the N-terminus of a calcium binding protein: alpha-lactalbumin

Fine tuning the N‐terminus of a calcium binding protein: α‐lactalbumin

High-throughput Site-directed Scanning Mutagenesis Using a Two-fragment PCR Approach

High-throughput mutagenesis using a two-fragment PCR approach

Hsp90-Tau complex reveals molecular basis for specificity in chaperone action

Human full-length Securin is a natively unfolded protein

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium

Insights into congenital stationary night blindness based on the structure of G90D rhodopsin

Insights into the Basal Activity and Activation Mechanism of the β1 Adrenergic Receptor Using Native Mass Spectrometry

Interactions of alpha-lactalbumins with lipid vesicles studied by tryptophan fluorescence.

Kinetic Instability of p53 Core Domain Mutants

Large-scale production and protein engineering of G protein-coupled receptors for structural studies

Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography

Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2.

Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists

Modulation of binding of DNA to the C-terminal domain of p53 by acetylation

Modulation of the oligomerization state of p53 by differential binding of proteins of the S100 family to p53 monomers and tetramers

Molecular basis for modulation of the p53 target selectivity by KLF4.

Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73.

Mutating aspartate in the calcium-binding site of alpha-lactalbumin: effects on the protein stability and cation binding

Native Mass Spectrometry Gives Insight into the Allosteric Binding Mechanism of M2 Pyruvate Kinase to Fructose-1,6-Bisphosphate.

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

Pb2+ and Hg2+ binding to alpha-lactalbumin

Probing Gαi1 protein activation at single-amino acid resolution.

Production and purification of human Hsp90β in Escherichia coli

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

Recognition of DNA by p53 Core Domain and Location of Intermolecular Contacts of Cooperative Binding

Regulation of DNA binding of p53 by its C-terminal domain

Sequence determinants of a microtubule tip localization signal (MtLS).

Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins

Stability of p53 homologs

Stabilization of G protein-coupled receptors by point mutations

Structural and mutational analysis of the cell division protein FtsQ

Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

Structural insight into the ESCRT-I/-II link and its role in MVB trafficking

Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies.

Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F

Structure of a human inositol 1,4,5-trisphosphate 3-kinase: substrate binding reveals why it is not a phosphoinositide 3-kinase

Structures of SAS-6 suggest its organization in centrioles

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations