Lista de obras - Matthew D Cheeseman - Dominio Público Uruguay

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.

artículo científico publicado en 2016

A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

artículo científico publicado en 2005

A temporary stereocentre approach for the asymmetric synthesis of chiral cyclopropane-carboxaldehydes

artículo científico publicado en 2009

An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56

artículo científico publicado en 2017

Asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters

artículo científico publicado en 2011

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766).

artículo científico publicado en 2017

Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9.

artículo científico publicado en 2016

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

artículo científico publicado en 2016

Efficient asymmetric synthesis of chiral hydroxy-gamma-butyrolactones

artículo científico publicado en 2009

Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70.

artículo científico publicado en 2016

Flexible strategy for the synthesis of pyrrolizidine alkaloids

artículo científico publicado en 2008

Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition

artículo científico publicado en 2015

Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72

artículo científico publicado en 2019

Lysine-Targeting Covalent Inhibitors.

artículo científico

N-N bond-forming cyclization for the one-pot synthesis of N-aryl[3,4-d]pyrazolopyrimidines.

artículo científico publicado en 2012

Privileged Structures and Polypharmacology within and between Protein Families.

artículo científico publicado en 2018

Stereoselective synthesis of (E)-trisubstituted alpha,beta-unsaturated amides and acids

scientific article published on 30 June 2005

Synthesis of (+)-DGDP and (-)-7-epialexine

artículo científico publicado en 2008

Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex

artículo científico publicado en 2017

Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines.

artículo científico publicado en 2014

Lista de obras de Matthew D Cheeseman

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.

A novel strategy for the asymmetric synthesis of chiral cyclopropane carboxaldehydes

A temporary stereocentre approach for the asymmetric synthesis of chiral cyclopropane-carboxaldehydes

An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56

Asymmetric synthesis of chiral δ-lactones containing multiple contiguous stereocenters

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766).

Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9.

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

Efficient asymmetric synthesis of chiral hydroxy-gamma-butyrolactones

Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70.

Flexible strategy for the synthesis of pyrrolizidine alkaloids

Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition

Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72

Lysine-Targeting Covalent Inhibitors.

N-N bond-forming cyclization for the one-pot synthesis of N-aryl[3,4-d]pyrazolopyrimidines.

Privileged Structures and Polypharmacology within and between Protein Families.

Stereoselective synthesis of (E)-trisubstituted alpha,beta-unsaturated amides and acids

Synthesis of (+)-DGDP and (-)-7-epialexine

Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex

Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines.