Lista de obras - Ramón García-Escudero - Dominio Público Uruguay

438 Function and Regulation of G-protein-coupled Receptor Kinase 2 (GRK2) in Tumor Progression of Stratified Epithelia

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

artículo científico publicado en 2020

A Polycomb-mir200 loop regulates clinical outcome in bladder cancer

artículo científico publicado en 2015

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours

artículo científico publicado en 2015

A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling

artículo científico publicado en 2010

A humanized mouse model of HPV-associated pathology driven by E7 expression

artículo científico publicado en 2012

A novel tumor suppressor network in squamous malignancies

artículo científico publicado en 2012

A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.

artículo científico publicado en 2017

Abstract 1451: MicroRNAs regulated by ESE3/EHF control important mediators of epithelial cell differentiation and stemness in prostate tumors

Abstract 147: Epigenetic networks and promoter-associated long noncoding RNAs (paRNAs) in prostate cancer

Abstract 2349: An RNA-based epigenetic network controls the expression of E-cadherin in epithelial normal and cancer cells

Abstract 2625: Targeting prostate cancer stem cells (CSCs) with the novel BET bromodomain (BRD) protein inhibitor OTX015

Abstract 4968: microRNA-mediated silencing of COP1 and altered ubiquitination of key oncogenic transcription factors promote cancer stem cell (CSC) phenotype and prostate cancer progression

Abstract 953: Novel inhibitors of signal transducer and activator of transcription 3 (STAT3) show potent activity in cell cultures and tumor xenografts

article

African Swine Fever Virus Structural Protein pE120R Is Essential for Virus Transport from Assembly Sites to Plasma Membrane but Not for Infectivity

artículo científico publicado en 2001

African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages.

artículo científico publicado en 2006

African swine fever virus structural protein p54 is essential for the recruitment of envelope precursors to assembly sites

artículo científico publicado en 2004

Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.

artículo científico publicado en 2009

Akt signaling leads to stem cell activation and promotes tumor development in epidermis.

artículo científico publicado en 2014

Analysis Models for HPV-Related Pathobiology

Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy.

artículo científico publicado en 2018

Bosutinib Inhibits EGFR Activation in Head and Neck Cancer

artículo científico publicado en 2018

CDK4/6 Inhibitor as a Novel Therapeutic Approach for Advanced Bladder Cancer Independently of RB1 Status

scientific article published on 21 September 2018

Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo.

artículo científico publicado en 2012

Clusterization in head and neck squamous carcinomas based on lncRNA expression: molecular and clinical correlates

Clusterization in head and neck squamous carcinomas based on lncRNA expression: molecular and clinical correlates.

artículo científico publicado en 2017

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

artículo científico publicado en 2018

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

artículo científico publicado en 2007

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

artículo científico publicado en 2017

DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA.

artículo científico publicado en 2003

Deciphering the complexity of human non-coding promoter-proximal transcriptome

artículo científico publicado en 2019

Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis

artículo científico publicado en 2007

Developmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2

artículo científico publicado en 2013

E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis

artículo científico publicado en 2012

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours

artículo científico publicado en 2012

ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progression

artículo científico publicado en 2013

Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity

scientific article published on 25 September 2014

Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12,

scientific article published on 14 October 2020

G-protein-coupled receptor kinase 2 safeguards epithelial phenotype in head and neck squamous cell carcinomas

scientific article published on 18 December 2019

Gene expression profiling as a tool for basic analysis and clinical application of human cancer.

artículo científico publicado en 2008

Gene expression profiling of mouse epidermal keratinocytes

scientific article published on January 2010

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

artículo científico publicado en 2010

Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis.

artículo científico publicado en 2008

Human papillomavirus type 77 E6 protein selectively inhibits p53-dependent transcription of proapoptotic genes following UV-B irradiation.

artículo científico publicado en 2004

Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors

artículo científico publicado en 2021

In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.

artículo científico publicado en 2014

Interaction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer.

artículo científico publicado en 2015

Keratinocyte cell lines derived from severe generalized recessive epidermolysis bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo

artículo científico publicado en 2013

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression

artículo científico publicado en 2016

Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression Profiling

artículo científico publicado en 2009

Molecular determinants of Akt-induced keratinocyte transformation

artículo científico publicado en 2006

Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes

artículo científico publicado en 2012

Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway.

artículo científico publicado en 2018

PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors

artículo científico publicado en 2013

Prostaglandin F2α-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity

scientific article published on 14 November 2019

Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression

scholarly article published 18 September 2018

Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts

artículo científico publicado en 2012

Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

artículo científico publicado en 2018

RNAi-mediated silencing of Myc transcription inhibits stem-like cell maintenance and tumorigenicity in prostate cancer.

artículo científico publicado en 2013

Repression of African swine fever virus polyprotein pp220-encoding gene leads to the assembly of icosahedral core-less particles.

artículo científico publicado en 2002

Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria

artículo científico publicado en 2006

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

artículo científico publicado en 2016

Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

scientific article published on 01 February 2008

Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage.

artículo científico publicado en 2008

Tau mRNA 3'UTR-to-CDS ratio is increased in Alzheimer disease

artículo científico publicado en 2017

The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures.

artículo científico publicado en 2011

The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin.

artículo científico publicado en 2005

The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas

artículo científico publicado en 2020

The IDH-Tau-EGFR triad defines diffuse glioma pathology by controlling mesenchymal differentiation and neo-vascular fitness

The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops

artículo científico publicado en 2013

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

artículo científico publicado en 2016

The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.

artículo científico publicado en 2012

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

artículo científico publicado en 2016

The structural protein p54 is essential for African swine fever virus viability

artículo científico publicado en 1996

Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer

artículo científico publicado en 2012

Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer.

artículo científico publicado en 2014

UV-B irradiation stimulates the promoter activity of the high-risk, cutaneous human papillomavirus 5 and 8 in primary keratinocytes

artículo científico publicado en 2004

Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

artículo científico publicado en 2018

WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth

artículo científico publicado en 2016

XPO7 is a tumor suppressor regulating p21<sup>CIP1</sup>-dependent senescence

artículo científico publicado en 2021

p107 acts as a tumor suppressor in pRb-deficient epidermis.

artículo científico publicado en 2008

p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia

artículo científico publicado en 2013

p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes

artículo científico publicado en 2011

Lista de obras de Ramón García-Escudero

438 Function and Regulation of G-protein-coupled Receptor Kinase 2 (GRK2) in Tumor Progression of Stratified Epithelia

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

A Polycomb-mir200 loop regulates clinical outcome in bladder cancer

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours

A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling

A humanized mouse model of HPV-associated pathology driven by E7 expression

A novel tumor suppressor network in squamous malignancies

A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.

Abstract 1451: MicroRNAs regulated by ESE3/EHF control important mediators of epithelial cell differentiation and stemness in prostate tumors

Abstract 147: Epigenetic networks and promoter-associated long noncoding RNAs (paRNAs) in prostate cancer

Abstract 2349: An RNA-based epigenetic network controls the expression of E-cadherin in epithelial normal and cancer cells

Abstract 2625: Targeting prostate cancer stem cells (CSCs) with the novel BET bromodomain (BRD) protein inhibitor OTX015

Abstract 4968: microRNA-mediated silencing of COP1 and altered ubiquitination of key oncogenic transcription factors promote cancer stem cell (CSC) phenotype and prostate cancer progression

Abstract 953: Novel inhibitors of signal transducer and activator of transcription 3 (STAT3) show potent activity in cell cultures and tumor xenografts

African Swine Fever Virus Structural Protein pE120R Is Essential for Virus Transport from Assembly Sites to Plasma Membrane but Not for Infectivity

African swine fever virus protein pE296R is a DNA repair apurinic/apyrimidinic endonuclease required for virus growth in swine macrophages.

African swine fever virus structural protein p54 is essential for the recruitment of envelope precursors to assembly sites

Akt activation synergizes with Trp53 loss in oral epithelium to produce a novel mouse model for head and neck squamous cell carcinoma.

Akt signaling leads to stem cell activation and promotes tumor development in epidermis.

Analysis Models for HPV-Related Pathobiology

Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy.

Bosutinib Inhibits EGFR Activation in Head and Neck Cancer

CDK4/6 Inhibitor as a Novel Therapeutic Approach for Advanced Bladder Cancer Independently of RB1 Status

Cell fusion reprogramming leads to a specific hepatic expression pattern during mouse bone marrow derived hepatocyte formation in vivo.

Clusterization in head and neck squamous carcinomas based on lncRNA expression: molecular and clinical correlates

Clusterization in head and neck squamous carcinomas based on lncRNA expression: molecular and clinical correlates.

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.

Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling

Correction: The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

DNA polymerase X of African swine fever virus: insertion fidelity on gapped DNA substrates and AP lyase activity support a role in base excision repair of viral DNA.

Deciphering the complexity of human non-coding promoter-proximal transcriptome

Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis

Developmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2

E2F1 loss induces spontaneous tumour development in Rb-deficient epidermis

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours

ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progression

Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity

Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12,

G-protein-coupled receptor kinase 2 safeguards epithelial phenotype in head and neck squamous cell carcinomas

Gene expression profiling as a tool for basic analysis and clinical application of human cancer.

Gene expression profiling of mouse epidermal keratinocytes

Gene expression profiling of mouse p53-deficient epidermal carcinoma defines molecular determinants of human cancer malignancy

Gene profiling approaches help to define the specific functions of retinoblastoma family in epidermis.

Human papillomavirus type 77 E6 protein selectively inhibits p53-dependent transcription of proapoptotic genes following UV-B irradiation.

Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors

In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.

Interaction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer.

Keratinocyte cell lines derived from severe generalized recessive epidermolysis bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression

Molecular Signature of HPV-Induced Carcinogenesis: pRb, p53 and Gene Expression Profiling

Molecular determinants of Akt-induced keratinocyte transformation

Mouse p53-deficient cancer models as platforms for obtaining genomic predictors of human cancer clinical outcomes

Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway.

PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors

Prostaglandin F2α-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity

Prostaglandin F2α-induced TGFβ-PMEPA1 pathway is a critical mediator of epithelial plasticity and ovarian carcinoma progression

Protein kinase C (PKC)ζ-mediated Gαq stimulation of ERK5 protein pathway in cardiomyocytes and cardiac fibroblasts

Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

RNAi-mediated silencing of Myc transcription inhibits stem-like cell maintenance and tumorigenicity in prostate cancer.

Repression of African swine fever virus polyprotein pp220-encoding gene leads to the assembly of icosahedral core-less particles.

Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of Retinoblastoma and Trp53 Tumor Suppressors

Susceptibility of pRb-deficient epidermis to chemical skin carcinogenesis is dependent on the p107 allele dosage.

Tau mRNA 3'UTR-to-CDS ratio is increased in Alzheimer disease

The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures.

The E7 protein of cutaneous human papillomavirus type 8 causes invasion of human keratinocytes into the dermis in organotypic cultures of skin.

The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas

The IDH-Tau-EGFR triad defines diffuse glioma pathology by controlling mesenchymal differentiation and neo-vascular fitness

The Rho exchange factors Vav2 and Vav3 favor skin tumor initiation and promotion by engaging extracellular signaling loops

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

The rho exchange factors vav2 and vav3 control a lung metastasis-specific transcriptional program in breast cancer cells.

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

The structural protein p54 is essential for African swine fever virus viability

Transcriptional and Non-Transcriptional Functions of PPARβ/δ in Non-Small Cell Lung Cancer

Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer.

UV-B irradiation stimulates the promoter activity of the high-risk, cutaneous human papillomavirus 5 and 8 in primary keratinocytes

Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth