Lista de obras - Adrienne M Gorman - Dominio Público Uruguay

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

artículo científico publicado en 2014

Antioxidant-mediated inhibition of the heat shock response leads to apoptosis

scientific article published on 01 February 1999

Antiproliferative action of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor

artículo científico publicado en 1989

Application of a fluorometric assay to detect caspase activity in thymus tissue undergoing apoptosis in vivo

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

artículo científico publicado en 2018

Cell stress and cell death

artículo científico publicado en 2010

Cellular longevity: role of apoptosis and replicative senescence

artículo científico publicado en 2002

Cellular stress responses: cell survival and cell death

artículo científico publicado en 2010

Challenging the dogmas. .

artículo científico publicado en 1999

Considerations and recent advances in neuroscience

artículo científico publicado en 2009

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases

scientific article published on 14 November 2018

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

artículo científico publicado en 2006

Dexamethasone pre-treatment interferes with apoptotic death in glioma cells.

artículo científico publicado en 2000

Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion

artículo científico publicado en 2013

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling

artículo científico publicado en 2019

Effect of functionalized micropatterned PLGA on guided neurite growth

artículo científico publicado en 2008

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

scientific article published on 04 August 2018

Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protoncogene expression

article

Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine

artículo científico publicado en 2006

Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.

artículo científico publicado en 2017

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response

artículo científico publicado en 2017

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

artículo científico publicado en 2017

Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells

artículo científico publicado en 2008

Heat shock protects PC12 cells against MPP+ toxicity

artículo científico publicado en 2003

Heat shock protein 27 in neuronal survival and neurite outgrowth

artículo científico publicado en 2009

Heat shock protein 70 reduces α-synuclein-induced predegenerative neuronal dystrophy in the α-synuclein viral gene transfer rat model of Parkinson's disease.

artículo científico publicado en 2013

Homology model of the human tRNA splicing ligase RtcB.

artículo científico publicado en 2017

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

artículo científico publicado en 2005

Hypoxia induces neurite outgrowth in PC12 cells that is mediated through adenosine A2A receptors

artículo científico publicado en 2005

Inhibition by anandamide of 6-hydroxydopamine-induced cell death in PC12 cells.

artículo científico publicado en 2010

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

artículo científico publicado en 2018

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β

scientific article published on 16 August 2019

Involvement of Akt in neurite outgrowth

artículo científico publicado en 2009

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

artículo científico publicado en 1994

Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat.

artículo científico publicado en 2010

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors

artículo científico publicado en 2019

Modulation by ionotropic excitatory amino acids and potassium of (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid-stimulated phosphoinositide hydrolysis in mouse cerebellar granule cells.

artículo científico publicado en 1995

Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells

artículo científico publicado en 2016

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

scientific journal article

Nerve growth factor in cancer cell death and survival

artículo científico publicado en 2011

Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner. ⬇️

artículo científico publicado en 2014

Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling

artículo científico publicado en 2008

Neurotrophins and B-cell malignancies

artículo científico

On the role of Hsp27 in regulating apoptosis

artículo científico publicado en 2003

RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells

artículo científico publicado en 2018

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

artículo científico publicado en 2022

Regulation of lipid metabolism by the unfolded protein response

artículo científico publicado en 2021

Stress management at the ER: regulators of ER stress-induced apoptosis

artículo científico

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

artículo científico publicado en 2012

Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors

artículo científico publicado en 1994

Sustained c-fos expression is associated with excitotoxicity during the development of neuronal cells in vitro

artículo científico publicado en 1996

Targeting the angio-proteostasis network: Combining the forces against cancer

artículo científico publicado en 2016

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

artículo científico publicado en 2009

The Unfolded Protein Response in Breast Cancer

artículo científico publicado en 2018

The eIF2α kinases: their structures and functions

artículo científico

The effect of laminin peptide gradient in enzymatically cross-linked collagen scaffolds on neurite growth

artículo científico publicado en 2010

The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats

artículo científico publicado en 2010

The effects of the peripheral-type benzodiazepine acceptor ligands, Ro 5-4864 and PK 11195, on mitochondrial respiration

artículo científico publicado el 1 de marzo de 1992

The integrated stress response.

artículo científico publicado en 2016

The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance

artículo científico publicado en 2013

The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia.

artículo científico publicado en 1996

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.

artículo científico

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

artículo científico publicado en 2011

Use of flow cytometry techniques in studying mechanisms of apoptosis in leukemic cells ⬇️

artículo científico publicado el 1 de octubre de 1997

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Adrienne M Gorman

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

Antioxidant-mediated inhibition of the heat shock response leads to apoptosis

Antiproliferative action of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor

Application of a fluorometric assay to detect caspase activity in thymus tissue undergoing apoptosis in vivo

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

Cell stress and cell death

Cellular longevity: role of apoptosis and replicative senescence

Cellular stress responses: cell survival and cell death

Challenging the dogmas. .

Considerations and recent advances in neuroscience

Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases

Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.

Dexamethasone pre-treatment interferes with apoptotic death in glioma cells.

Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling

Effect of functionalized micropatterned PLGA on guided neurite growth

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

Excitatory amino acid-induced cytotoxicity in primary cultures of mouse cerebellar granule cells correlates with elevated, sustained c-fos protoncogene expression

Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine

Generation of rationally-designed nerve growth factor (NGF) variants with receptor specificity.

Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

Heat shock enhances NGF-induced neurite elongation which is not mediated by Hsp25 in PC12 cells

Heat shock protects PC12 cells against MPP+ toxicity

Heat shock protein 27 in neuronal survival and neurite outgrowth

Heat shock protein 70 reduces α-synuclein-induced predegenerative neuronal dystrophy in the α-synuclein viral gene transfer rat model of Parkinson's disease.

Homology model of the human tRNA splicing ligase RtcB.

Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells

Hypoxia induces neurite outgrowth in PC12 cells that is mediated through adenosine A2A receptors

Inhibition by anandamide of 6-hydroxydopamine-induced cell death in PC12 cells.

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β

Involvement of Akt in neurite outgrowth

L-TRANs-Pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1, 3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters

Loss of cannabinoid CB1 receptor expression in the 6-hydroxydopamine-induced nigrostriatal terminal lesion model of Parkinson's disease in the rat.

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors

Modulation by ionotropic excitatory amino acids and potassium of (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid-stimulated phosphoinositide hydrolysis in mouse cerebellar granule cells.

Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells

Nerve growth factor blocks thapsigargin-induced apoptosis at the level of the mitochondrion via regulation of Bim

Nerve growth factor in cancer cell death and survival

Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner. ⬇️

Neuronal cell death in neurodegenerative diseases: recurring themes around protein handling

Neurotrophins and B-cell malignancies

On the role of Hsp27 in regulating apoptosis

RIP2 enhances cell survival by activation of NF-ĸB in triple negative breast cancer cells

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Regulation of lipid metabolism by the unfolded protein response

Stress management at the ER: regulators of ER stress-induced apoptosis

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

Sulphur-containing excitatory amino acid-stimulated inositol phosphate formation in primary cultures of cerebellar granule cells is mediated predominantly by N-methyl-D-aspartate receptors

Sustained c-fos expression is associated with excitotoxicity during the development of neuronal cells in vitro

Targeting the angio-proteostasis network: Combining the forces against cancer

Targeting the endoplasmic reticulum-stress response as an anticancer strategy

The Unfolded Protein Response in Breast Cancer

The eIF2α kinases: their structures and functions

The effect of laminin peptide gradient in enzymatically cross-linked collagen scaffolds on neurite growth

The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats

The effects of the peripheral-type benzodiazepine acceptor ligands, Ro 5-4864 and PK 11195, on mitochondrial respiration

The integrated stress response.

The novel toluidine sulphonamide EL102 shows pre-clinical in vitro and in vivo activity against prostate cancer and circumvents MDR1 resistance

The repression of apoptosis by activated abl oncogenes in chronic myelogenous leukaemia.

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders

Use of flow cytometry techniques in studying mechanisms of apoptosis in leukemic cells ⬇️

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)