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Lista de obras de Thomas Thum

A novel multi-parametric analysis of non-invasive methods to assess animal distress during chronic pancreatitis

scientific article published on 01 October 2019

A phenotypic screen to identify hypertrophy-modulating microRNAs in primary cardiomyocytes

artículo científico publicado en 2011

A practical guide for investigating cardiac physiology using living myocardial slices

scientific article published on 10 September 2020

A rapid and simple CYP2D6 genotyping assay--case study with the analgetic tramadol

artículo científico publicado en 2003

A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

artículo científico publicado en 2013

ADMA, endothelial progenitor cells, and cardiovascular risk.

artículo científico publicado en 2005

Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and d

artículo científico publicado en 2006

Activation of the miR-17 family and miR-21 during murine kidney ischemia-reperfusion injury.

artículo científico publicado en 2013

Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology

artículo científico publicado en 2020

Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1.

artículo científico publicado en 2007

Aldosterone mediated dysfunction of human endothelial progenitor cells - Mechanisms and therapeutic opportunities

Analytical approaches in microRNA therapeutics.

artículo científico publicado en 2014

Androgen metabolism in thymus of fetal and adult rats

artículo científico publicado en 2004

Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

artículo científico publicado en 2022

Annual meeting of the American Heart Association. Dallas, Texas, USA, 13-16 November 2005.

artículo científico publicado en 2006

Aroclor 1254 modulates gene expression of nuclear transcription factors: implications for albumin gene transcription and protein synthesis in rat hepatocyte cultures

scientific journal article

Aromatase inhibition attenuates desflurane-induced preconditioning against acute myocardial infarction in male mouse heart in vivo

artículo científico publicado en 2012

Association between Circular RNA CDR1as and Post-Infarction Cardiac Function in Pig Ischemic Heart Failure: Influence of the Anti-Fibrotic Natural Compounds Bufalin and Lycorine

artículo científico publicado en 2020

Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors

scientific article published on 02 September 2019

Biogenesis and regulation of cardiovascular microRNAs.

artículo científico publicado en 2011

Blood-based microRNA profiling in patients with cardiac amyloidosis

artículo científico publicado en 2018

Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cells

artículo científico publicado en 2006

Breakthrough in cachexia treatment through a novel selective androgen receptor modulator?!

artículo científico publicado en 2011

Butanedione monoxime increases the viability and yield of adult cardiomyocytes in primary cultures

artículo científico publicado en 2001

CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure

artículo científico publicado en 2020

Cardiac dissonance without conductors: how dicer depletion provokes chaos in the heart.

artículo científico publicado en 2008

Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

artículo científico publicado en 2014

Cardiac fibroblasts on the fast track--scleraxis: from Achilles' heel to anti-fibrotic therapy

artículo científico publicado en 2009

Cardiac fibrosis revisited by microRNA therapeutics

scientific article published on 18 July 2012

Cardiac regeneration by progenitor cells--bedside before bench?

artículo científico publicado en 2005

Cardiovascular importance of the microRNA-23/27/24 family

artículo científico publicado en 2012

Cellular dedifferentiation of endothelium is linked to activation and silencing of certain nuclear transcription factors: implications for endothelial dysfunction and vascular biology.

artículo científico

Circulating and urinary microRNAs in kidney disease.

artículo científico

Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension.

artículo científico publicado en 2008

Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure

artículo científico publicado en 2014

Circulating miR-133a and miR-423-5p fail as biomarkers for left ventricular remodeling after myocardial infarction

scientific article published on 22 January 2013

Circulating miR-210 predicts survival in critically ill patients with acute kidney injury

artículo científico publicado en 2011

Circulating miR-423_5p fails as a biomarker for systemic ventricular function in adults after atrial repair for transposition of the great arteries.

artículo científico publicado en 2011

Circulating microRNAs are not eliminated by hemodialysis

artículo científico publicado en 2012

Circulating microRNAs as biomarkers and potential paracrine mediators of cardiovascular disease

scientific article published on 01 October 2010

Circulating microRNAs as potential biomarkers of aerobic exercise capacity

artículo científico publicado en 2013

Circulating microRNAs in Fabry Disease

artículo científico publicado en 2019

Circulating microRNAs in patients with Shiga-Toxin-producing E. coli O104:H4 induced hemolytic uremic syndrome

artículo científico publicado en 2012

Common Mechanistic Pathways in Cancer and Heart Failure

artículo científico publicado en 2020

Comparison of different miR-21 inhibitor chemistries in a cardiac disease model

artículo científico publicado en 2011

Conversion from conventional in-centre thrice-weekly haemodialysis to short daily home haemodialysis ameliorates uremia-associated clinical parameters

artículo científico publicado en 2011

Cytochrome P450 mono-oxygenase gene expression and protein activity in cultures of adult cardiomyocytes of the rat.

artículo científico publicado en 2000

Detection and transport mechanisms of circulating microRNAs in neurological, cardiac and kidney diseases.

artículo científico

Detection of early signals of hepatotoxicity by gene expression profiling studies with cultures of metabolically competent human hepatocytes

scientific article published on 13 September 2007

Development and characterization of anti-fibrotic natural compound similars with improved effectivity

scientific article published on 02 March 2022

Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome

artículo científico publicado en 2011

ESC Working Group on Myocardial Function Position Paper: how to study the right ventricle in experimental models

artículo científico

Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial

artículo científico publicado en 2008

Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis

artículo científico publicado en 2008

Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence

artículo científico publicado en 2004

Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes

artículo científico publicado en 2007

Endothelial progenitor cell dysfunction: mechanisms and therapeutic approaches

artículo científico publicado en 2007

Endothelial progenitor cells in pulmonary arterial hypertension.

artículo científico publicado en 2010

Epigenetic modifications in cardiovascular disease.

artículo científico publicado en 2012

Erythropoietin in Kidney Disease and Type 2 Diabetes ⬇️

artículo científico publicado el 27 de enero de 2011

European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose-lowering drugs in patients with heart failure

scientific article published on 09 December 2019

Exosomes: new players in cell-cell communication.

artículo científico

Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers

artículo científico publicado en 2006

Functional microRNA library screening identifies the hypoxamir miR-24 as a potent regulator of smooth muscle cell proliferation and vascularization

artículo científico publicado en 2013

GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in v

artículo científico publicado en 2007

Gene expression in distinct regions of the heart

artículo científico publicado en 2000

Glucocorticoid insensitivity at the hypoxic blood-brain barrier can be reversed by inhibition of the proteasome.

artículo científico publicado en 2011

Growth hormone induces eNOS expression and nitric oxide release in a cultured human endothelial cell line.

artículo científico publicado en 2003

Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-I

scientific article published on 28 August 2007

Growth hormone treatment improves markers of systemic nitric oxide bioavailability via the insulin-like growth factor-1 Importance for endothelial progenitor cells

Hallmarks of ion channel gene expression in end-stage heart failure

artículo científico publicado en 2003

Heart Failure Association of the European Society of Cardiology Update on Sodium Glucose Co-transporter-2 Inhibitors in Heart Failure (an update on the Sodium-glucose co-transporter 2 inhibitors in heart failure: beyond glycaemic control. The positi

artículo científico publicado en 2020

Heterocellular signalling and crosstalk in the heart in ischaemia and heart failure

artículo científico publicado en 2014

Identification of cardiovascular microRNA targetomes.

artículo científico publicado en 2011

Identification of major CYP2C9 and CYP2C19 polymorphisms by fluorescence resonance energy transfer analysis

artículo científico publicado en 2002

Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model

artículo científico publicado en 2014

Impairment of endothelial progenitor cell function and vascularization capacity by aldosterone in mice and humans

artículo científico publicado en 2010

Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction

artículo científico publicado en 2008

Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper

artículo científico publicado en 2008

Induction of nuclear transcription factors, cytochrome P450 monooxygenases, and glutathione S-transferase alpha gene expression in Aroclor 1254-treated rat hepatocyte cultures.

artículo científico publicado en 2001

Inhibition of proteasome-mediated glucocorticoid receptor degradation restores nitric oxide bioavailability in myocardial endothelial cells in vitro.

artículo científico publicado en 2014

Integrative Bioinformatic Analyses of Global Transcriptome Data Decipher Novel Molecular Insights into Cardiac Anti-Fibrotic Therapies ⬇️

artículo científico publicado en 2020

Isolation and cultivation of Ca2+ tolerant cardiomyocytes from the adult rat: improvements and applications

artículo científico publicado en 2000

LC-MS/MS and GC-MS/MS measurement of plasma and urine di-paracetamol and 3-nitro-paracetamol: proof-of-concept studies on a novel human model of oxidative stress based on oral paracetamol administration

artículo científico publicado en 2014

LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases

scientific article (publication date: 21 July 2000)

LINCing MALAT1 and angiogenesis

artículo científico publicado en 2014

LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium

artículo científico publicado en 2008

Letter by Thum et al regarding article, "Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma ag

artículo científico publicado en 2008

Limitations of gait speed as an independent predictor of mortality and morbidity in cardiac patients

scientific article published on 01 August 2011

Liraglutide for weight loss in obese people

artículo científico publicado en 2010

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

artículo científico publicado en 2013

Malfunction of endothelial progenitor cells and endothelial function in patients with Fabry disease

Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease

artículo científico publicado en 2010

Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.

artículo científico publicado en 2007

Mechanistic role of cytochrome P450 monooxygenases in oxidized low-density lipoprotein-induced vascular injury: therapy through LOX-1 receptor antagonism?

artículo científico publicado en 2003

Metabolism of verapamil: 24 new phase I and phase II metabolites identified in cell cultures of rat hepatocytes by liquid chromatography-tandem mass spectrometry

artículo científico publicado en 2003

MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors

artículo científico publicado en 2013

MicroRNA target sites as genetic tools to enhance promoter-reporter specificity for the purification of pancreatic progenitor cells from differentiated embryonic stem cells.

artículo científico publicado en 2013

MicroRNA therapeutics in cardiovascular medicine ⬇️

artículo científico publicado el 13 de diciembre de 2011

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

scientific journal article

MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart ⬇️

artículo científico publicado el 27 de abril de 2012

MicroRNA-223 made its way into vascular research

artículo científico publicado en 2013

MicroRNA-24 antagonism prevents renal ischemia reperfusion injury

artículo científico publicado en 2014

MicroRNA-24 regulates vascularity after myocardial infarction

artículo científico publicado en 2011

MicroRNA-based therapy in cardiology

artículo científico publicado en 2014

MicroRNAs and vascular (dys)function.

artículo científico publicado en 2011

MicroRNAs as circulating biomarkers for heart failure: questions about MiR-423-5p

artículo científico publicado en 2010

MicroRNAs as mediators and therapeutic targets in chronic kidney disease ⬇️

artículo científico publicado el 22 de marzo de 2011

MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: protectomiRs

artículo científico publicado en 2014

MicroRNAs deciding cardiac stem cell fate

artículo científico publicado en 2012

MicroRNAs in diabetes and diabetes-associated complications ⬇️

artículo científico publicado el 1 de junio de 2012

MicroRNAs in hypertension: mechanisms and therapeutic targets.

artículo científico

MicroRNAs in idiopathic childhood nephrotic syndrome

artículo científico publicado en 2013

MicroRNAs in myocardial infarction.

artículo científico publicado en 2013

MicroRNAs in platelet biogenesis and function

scientific article published on 10 July 2012

MicroRNAs in platelet physiology and pathology.

artículo científico publicado en 2013

MicroRNAs in the bile of patients with biliary strictures after liver transplantation

artículo científico publicado en 2014

MicroRNAs in the broken heart.

artículo científico publicado en 2007

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure

artículo científico publicado en 2007

MicroRNAs in vascular biology – metabolism and atherosclerosis

artículo científico publicado en 2012

MicroRNAs looping around angiogenesis

artículo científico publicado en 2011

MicroRNAs play a role in spontaneous recovery from acute liver failure

artículo científico publicado en 2014

MicroRNAs: from basic regulation towards therapeutic approaches--passion, caution and patience required

artículo científico publicado en 2010

MicroRNA‐Based Therapeutic Approaches in the Cardiovascular System ⬇️

artículo científico publicado el 14 de octubre de 2010

Microparticles and microRNAs of endothelial progenitor cells ameliorate acute kidney injury ⬇️

artículo científico publicado el 1 de agosto de 2012

Microvesicles as novel biomarkers and therapeutic targets in transplantation medicine.

artículo científico publicado en 2011

Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function: simply effects of optimized drug treatment?

artículo científico publicado en 2005

Molecular diagnosis of a familial nonhemolytic hyperbilirubinemia (Gilbert's syndrome) in healthy subjects

artículo científico publicado en 2000

New insight into healing mechanisms of the infarcted heart

artículo científico publicado en 2010

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

scientific journal article

No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure

scientific article published on 23 August 2008

Non-coding RNAs in cardiac remodeling and heart failure.

artículo científico publicado en 2013

Non-coding RNAs in cardiovascular ageing

artículo científico

Non-coding RNAs: key players in cardiac disease

scientific article published on 10 July 2019

Novel biomarkers for acute myocardial infarction: is microRNA the new kid on the block?

artículo científico publicado en 2013

Novel non‐coding RNA‐based therapeutic approaches to prevent statin‐induced liver damage ⬇️

artículo científico publicado el 20 de agosto de 2012

Novel techniques and targets in cardiovascular microRNA research

artículo científico publicado en 2012

Nutritional iron deficiency in patients with chronic illnesses

artículo científico publicado en 2007

Obesity and risk of myocardial infarction: the INTERHEART study

artículo científico publicado en 2006

Organic nitrates differentially modulate circulating endothelial progenitor cells and endothelial function in patients with symptomatic coronary artery disease

artículo científico publicado en 2011

PCBs alter gene expression of nuclear transcription factors and other heart-specific genes in cultures of primary cardiomyocytes: possible implications for cardiotoxicity

artículo científico publicado en 2002

Pathologic endothelial response and impaired function of circulating angiogenic cells in patients with Fabry disease

artículo científico publicado en 2012

Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension.

artículo científico publicado en 2017

Preclinical development of a miR-132 inhibitor for heart failure treatment

artículo científico publicado en 2020

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

artículo científico

RNA-based diagnostic and therapeutic strategies for cardiovascular disease

scientific article published on 11 June 2019

Recent patents on cardiovascular stem cells

scientific article published on 01 January 2008

Recent patents on stem cell transplantation in cardiovascular medicine

Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study

artículo científico publicado en 2012

Regulation and function of miRNA-21 in health and disease.

artículo científico publicado en 2011

Regulation of cardiac and renal ischemia–reperfusion injury by microRNAs ⬇️

artículo científico publicado el 8 de julio de 2013

Regulatory RNAs and paracrine networks in the heart.

artículo científico

Remodelling of adult cardiac tissue subjected to physiological and pathological mechanical load in vitro

artículo científico publicado en 2022

Reprogramming of gene expression in cultured cardiomyocytes and in explanted hearts by the myosin ATPase inhibitor butanedione monoxime

artículo científico publicado en 2001

Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.

artículo científico publicado en 2010

Review focus on the role of microRNA in cardiovascular biology and disease ⬇️

artículo científico publicado el 7 de febrero de 2012

Role of miR-21 in the pathogenesis of atrial fibrosis

artículo científico publicado en 2012

Role of microRNAs in immunity and organ transplantation.

artículo científico publicado en 2011

SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway

scientific journal article

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation ⬇️

artículo científico publicado el 4 de septiembre de 2012

Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism

scientific journal article

Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes

artículo científico publicado en 2010

Sodium glucose co-transporter-2 inhibitors in heart failure: beyond glycaemic control. The Position Paper of the Heart Failure Association of the European Society of Cardiology

artículo científico publicado en 2020

Sports or statins for atheroprotection? New insight from Kruppel-like factor 2

scientific article published on 30 August 2006

Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine

artículo científico publicado en 2005

TLR-4+ peripheral blood monocytes and cardiovascular events in patients with chronic kidney disease--a prospective follow-up study

artículo científico publicado en 2011

TWIST1 regulates the activity of ubiquitin proteasome system via the miR-199/214 cluster in human end-stage dilated cardiomyopathy

artículo científico publicado en 2013

Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology

artículo científico publicado en 2014

Testosterone, cytochrome P450, and cardiac hypertrophy

artículo científico publicado en 2002

The BALANCE study too early to speculate on mortality effects

artículo científico publicado en 2010

The IGF-1 receptor as a therapeutic target to improve endothelial progenitor cell function

artículo científico publicado en 2008

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

artículo científico publicado en 2012

The smooth long noncoding RNA SENCR

artículo científico publicado en 2014

Tilarginine in patients with acute myocardial infarction and cardiogenic shock

artículo científico publicado en 2007

Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury.

artículo científico publicado en 2007

Transforming growth factor-β-induced endothelial-to-mesenchymal transition is partly mediated by microRNA-21.

artículo científico publicado en 2011

Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease ⬇️

artículo científico publicado el 14 de diciembre de 2010

Urinary miR-210 as a mediator of acute T-cell mediated rejection in renal allograft recipients

artículo científico publicado en 2011

Verapamil metabolism in distinct regions of the heart and in cultures of cardiomyocytes of adult rats.

artículo científico publicado en 2001

Verapamil: identification of novel metabolites in cultures of primary human hepatocytes and human urine by LC-MS(n) and LC-NMR.

artículo científico publicado en 2003

Verapamil: metabolism in cultures of primary human coronary arterial endothelial cells

artículo científico publicado en 2003

Verapamil: new insight into the molecular mechanism of drug oxidation in the human heart

artículo científico publicado en 2002

miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development.

artículo científico publicado en 2010

miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2.

artículo científico publicado en 2011

miRNAGE-34 induces cardiac damAGE.

artículo científico publicado en 2013

miRNAs involved in the generation, maintenance, and differentiation of pluripotent cells ⬇️

artículo científico publicado el 9 de junio de 2012

microRNA therapeutics in cardiovascular disease models.

artículo científico publicado en 2013

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