Lista de obras - Nico Lachmann - Dominio Público Uruguay

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny

artículo científico publicado en 2013

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

artículo científico publicado en 2018

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy

artículo científico publicado en 2011

Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells-Ready for Take-Off

scientific article published on 26 December 2018

Deoxycytidine-kinase knockdown as a novel myeloprotective strategy in the context of fludarabine, cytarabine or cladribine therapy.

artículo científico publicado en 2015

Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells

artículo científico publicado en 2011

Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

artículo científico publicado en 2012

Ex vivo Generation of Genetically Modified Macrophages from Human Induced Pluripotent Stem Cells.

artículo científico publicado en 2017

Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.

artículo científico publicado en 2014

Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions

artículo científico publicado en 2016

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

artículo científico publicado en 2017

Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-γR1 Deficiency

artículo científico publicado en 2020

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages

artículo científico publicado en 2017

In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application

artículo científico publicado en 2012

Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies

artículo científico publicado en 2015

Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.

artículo científico publicado en 2014

Lost in translation: pluripotent stem cell-derived hematopoiesis

artículo científico publicado en 2015

Lung surfactant metabolism: early in life, early in disease and target in cell therapy.

artículo científico publicado en 2016

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy

artículo científico publicado en 2011

MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.

artículo científico publicado en 2016

Monocyte/macrophage lineage commitment and distribution are affected by the lack of regulatory T cells in scurfy mice.

artículo científico publicado en 2016

Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.

artículo científico

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway

scientific article published on 19 February 2020

Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.

artículo científico publicado en 2013

Pulmonary Transplantation of Human iPSC-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.

artículo científico publicado en 2018

Pulmonary macrophage transplantation therapy

artículo científico publicado en 2014

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

artículo científico publicado en 2014

TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells

artículo científico publicado en 2015

TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis.

artículo científico publicado en 2017

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages

scientific article published on 03 April 2020

Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy.

artículo científico publicado en 2015

iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice

artículo científico publicado en 2018

Lista de obras de Nico Lachmann

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy

Concise Review: Towards the Clinical Translation of Induced Pluripotent Stem Cell-Derived Blood Cells-Ready for Take-Off

Deoxycytidine-kinase knockdown as a novel myeloprotective strategy in the context of fludarabine, cytarabine or cladribine therapy.

Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells

Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.

Ex vivo Generation of Genetically Modified Macrophages from Human Induced Pluripotent Stem Cells.

Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis.

Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions

Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections

Human Lentiviral Gene Therapy Restores the Cellular Phenotype of Autosomal Recessive Complete IFN-γR1 Deficiency

Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages

In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application

Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies

Lentiviral MGMT(P140K)-mediated in vivo selection employing a ubiquitous chromatin opening element (A2UCOE) linked to a cellular promoter.

Lost in translation: pluripotent stem cell-derived hematopoiesis

Lung surfactant metabolism: early in life, early in disease and target in cell therapy.

MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy

MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.

Monocyte/macrophage lineage commitment and distribution are affected by the lack of regulatory T cells in scurfy mice.

Myeloprotection by cytidine deaminase gene transfer in antileukemic therapy.

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway

Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy.

Pulmonary Transplantation of Human iPSC-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis.

Pulmonary macrophage transplantation therapy

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells

TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis.

Targeted Integration of Inducible Caspase-9 in Human iPSCs Allows Efficient in vitro Clearance of iPSCs and iPSC-Macrophages

Tightly regulated 'all-in-one' lentiviral vectors for protection of human hematopoietic cells from anticancer chemotherapy.

iPSC-Derived Macrophages Effectively Treat Pulmonary Alveolar Proteinosis in Csf2rb-Deficient Mice