Lista de obras - Kevin Wickman - Dominio Público Uruguay

A Role for the GIRK3 Subunit in Methamphetamine-Induced Attenuation of GABAB Receptor-Activated GIRK Currents in VTA Dopamine Neurons

artículo científico publicado en 2016

Abnormal heart rate regulation in GIRK4 knockout mice.

artículo científico publicado en 1998

Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.

artículo científico publicado en 2008

Acute cocaine exposure weakens GABA(B) receptor-dependent G-protein-gated inwardly rectifying K+ signaling in dopamine neurons of the ventral tegmental area.

artículo científico publicado en 2011

Altered neurotransmission in the mesolimbic reward system of Girk mice

artículo científico publicado en 2010

Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.

artículo científico publicado en 2013

Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.

artículo científico publicado en 2008

Behavioral characterization of mice lacking Trek channels ⬇️

artículo científico publicado el 7 de septiembre de 2012

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation

artículo científico publicado en 2014

Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum

artículo científico publicado en 2007

Cocaine-induced adaptations in metabotropic inhibitory signaling in the mesocorticolimbic system.

artículo científico publicado en 2012

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.

artículo científico publicado en 2006

Contribution of the Kir3.1 subunit to the muscarinic-gated atrial potassium channel IKACh

artículo científico publicado en 2002

Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain

artículo científico publicado en 2011

Differential GABAB-receptor-mediated effects in perisomatic- and dendrite-targeting parvalbumin interneurons

artículo científico publicado en 2013

Discovery and Characterization of 1H-Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2 Potassium Channel Activators

artículo científico publicado en 2017

Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels

artículo científico publicado en 2006

Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model.

artículo científico publicado en 2001

Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.

artículo científico publicado en 2007

G Protein-Gated K+ Channel Ablation in Forebrain Pyramidal Neurons Selectively Impairs Fear Learning.

artículo científico publicado en 2015

G beta gamma binds directly to the G protein-gated K+ channel, IKACh

scientific article published on 01 December 1995

G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.

artículo científico publicado en 2016

G-protein regulation of ion channels.

artículo científico publicado en 1995

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

artículo científico publicado en 2013

G-protein-gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by Opioids

artículo científico publicado en 2015

GIRK Channel Activity in Dopamine Neurons of the Ventral Tegmental Area Bidirectionally Regulates Behavioral Sensitivity to Cocaine

artículo científico publicado en 2019

GIRK Channel Plasticity and Implications for Drug Addiction.

artículo científico publicado en 2015

GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner

artículo científico publicado en 2015

GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior

artículo científico publicado en 2017

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol.

artículo científico publicado en 2015

GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells

artículo científico publicado en 2020

Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling.

artículo científico publicado en 2010

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways

artículo científico publicado en 2014

Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice

artículo científico publicado en 2002

ICln is essential for cellular and early embryonic viability.

artículo científico publicado en 2000

Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene.

artículo científico publicado en 2011

Impact of acute and persistent excitation of prelimbic pyramidal neurons on motor activity and trace fear learning

artículo científico publicado en 2021

Inhibition of Pyramidal Neurons in the Basal Amygdala Promotes Fear Learning

artículo científico publicado en 2018

Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol.

artículo científico publicado en 2009

Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.

artículo científico publicado en 2014

Molecular and cellular diversity of neuronal G-protein-gated potassium channels.

artículo científico publicado en 2005

New insights into the therapeutic potential of Girk channels.

artículo científico publicado en 2013

Partial structure, chromosome localization, and expression of the mouse Girk4 gene.

artículo científico publicado en 1997

Partial structure, chromosome localization, and expression of the mouse Icln gene

artículo científico publicado en 1997

Preface

Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes

artículo científico publicado en 2008

RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.

artículo científico publicado en 2007

RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate

artículo científico publicado en 2013

RGS6/Gβ5 Complex Accelerates I KACh Gating Kinetics in Atrial Myocytes and Modulates Parasympathetic Regulation of Heart Rate ⬇️

artículo científico publicado el 30 de septiembre de 2010

RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.

artículo científico publicado en 2014

Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex.

artículo científico publicado en 2013

Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice.

artículo científico publicado en 2016

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels

scientific journal article

Sex differences in GABA(B)R-GIRK signaling in layer 5/6 pyramidal neurons of the mouse prelimbic cortex

artículo científico publicado en 2015

Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.

artículo científico publicado en 2004

Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids.

artículo científico publicado en 2005

Structural characterization of the mouse Girk genes.

artículo científico publicado en 2002

Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel, IKACh

artículo científico publicado en 1999

Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.

artículo científico publicado en 2009

Suppression of inhibitory G protein signaling in forebrain pyramidal neurons triggers plasticity of glutamatergic neurotransmission in the nucleus accumbens core.

artículo científico publicado en 2017

Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice

scientific article published in 2021

Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism

scientific article published on 16 March 2020

The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I.

artículo científico publicado en 2005

Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress.

artículo científico publicado en 2005

VU0810464, a non-urea G protein-gated inwardly rectifying K+ (Kir 3/GIRK) channel activator, exhibits enhanced selectivity for neuronal Kir 3 channels and reduces stress-induced hyperthermia in mice

artículo científico publicado en 2019

Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons

artículo científico publicado en 2004

pICln Binds to a Mammalian Homolog of a Yeast Protein Involved in Regulation of Cell Morphology ⬇️

artículo científico publicado el 1 de mayo de 1998

Lista de obras de Kevin Wickman

A Role for the GIRK3 Subunit in Methamphetamine-Induced Attenuation of GABAB Receptor-Activated GIRK Currents in VTA Dopamine Neurons

Abnormal heart rate regulation in GIRK4 knockout mice.

Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.

Acute cocaine exposure weakens GABA(B) receptor-dependent G-protein-gated inwardly rectifying K+ signaling in dopamine neurons of the ventral tegmental area.

Altered neurotransmission in the mesolimbic reward system of Girk mice

Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.

Behavioral characterization of mice lacking GIRK/Kir3 channel subunits.

Behavioral characterization of mice lacking Trek channels ⬇️

Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation

Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum

Cocaine-induced adaptations in metabotropic inhibitory signaling in the mesocorticolimbic system.

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.

Contribution of the Kir3.1 subunit to the muscarinic-gated atrial potassium channel IKACh

Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain

Differential GABAB-receptor-mediated effects in perisomatic- and dendrite-targeting parvalbumin interneurons

Discovery and Characterization of 1H-Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2 Potassium Channel Activators

Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels

Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model.

Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases.

G Protein-Gated K+ Channel Ablation in Forebrain Pyramidal Neurons Selectively Impairs Fear Learning.

G beta gamma binds directly to the G protein-gated K+ channel, IKACh

G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.

G-protein regulation of ion channels.

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

G-protein-gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by Opioids

GIRK Channel Activity in Dopamine Neurons of the Ventral Tegmental Area Bidirectionally Regulates Behavioral Sensitivity to Cocaine

GIRK Channel Plasticity and Implications for Drug Addiction.

GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner

GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior

GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol.

GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells

Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling.

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways

Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice

ICln is essential for cellular and early embryonic viability.

Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene.

Impact of acute and persistent excitation of prelimbic pyramidal neurons on motor activity and trace fear learning

Inhibition of Pyramidal Neurons in the Basal Amygdala Promotes Fear Learning

Mapping a barbiturate withdrawal locus to a 0.44 Mb interval and analysis of a novel null mutant identify a role for Kcnj9 (GIRK3) in withdrawal from pentobarbital, zolpidem, and ethanol.

Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297.

Molecular and cellular diversity of neuronal G-protein-gated potassium channels.

New insights into the therapeutic potential of Girk channels.

Partial structure, chromosome localization, and expression of the mouse Girk4 gene.

Partial structure, chromosome localization, and expression of the mouse Icln gene

Preface

Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes

RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area.

RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate

RGS6/Gβ5 Complex Accelerates I KACh Gating Kinetics in Atrial Myocytes and Modulates Parasympathetic Regulation of Heart Rate ⬇️

RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.

Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex.

Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice.

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels

Sex differences in GABA(B)R-GIRK signaling in layer 5/6 pyramidal neurons of the mouse prelimbic cortex

Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia.

Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids.

Structural characterization of the mouse Girk genes.

Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel, IKACh

Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.

Suppression of inhibitory G protein signaling in forebrain pyramidal neurons triggers plasticity of glutamatergic neurotransmission in the nucleus accumbens core.

Suppression of pyramidal neuron G protein-gated inwardly rectifying K+ channel signaling impairs prelimbic cortical function and underlies stress-induced deficits in cognitive flexibility in male, but not female, mice

Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism

The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I.

Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress.

VU0810464, a non-urea G protein-gated inwardly rectifying K+ (Kir 3/GIRK) channel activator, exhibits enhanced selectivity for neuronal Kir 3 channels and reduces stress-induced hyperthermia in mice

Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons

pICln Binds to a Mammalian Homolog of a Yeast Protein Involved in Regulation of Cell Morphology ⬇️