Lista de obras - Jérémie Mortier - Dominio Público Uruguay

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

artículo científico publicado en 2015

An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides

artículo científico publicado en 2014

Anthocyanin composition, antioxidant efficiency, and α-amylase inhibitor activity of different Hungarian sour cherry varieties (Prunus cerasus L.).

artículo científico publicado en 2015

Anti-virulence strategy against Brucella suis: synthesis, biological evaluation and molecular modeling of selective histidinol dehydrogenase inhibitors

artículo científico publicado en 2011

Arginase Structure and Inhibition: Catalytic Site Plasticity Reveals New Modulation Possibilities

artículo científico publicado en 2017

Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics.

artículo científico publicado en 2015

Computational tools for in silico fragment-based drug design.

artículo científico publicado en 2012

Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C

scientific article published on 01 April 2020

Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity

artículo científico publicado en 2014

Design, synthesis and structure-activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor.

artículo científico publicado en 2013

Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans

artículo científico publicado en 2012

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

artículo científico publicado en 2014

From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors

artículo científico publicado en 2015

Identification of PPARγ Agonists from Natural Sources Using Different In Silico Approaches

artículo científico publicado en 2014

Impact of fluorination on proteolytic stability of peptides in human blood plasma

artículo científico publicado en 2013

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

artículo científico publicado en 2014

In silico virtual screening approaches for anti-viral drug discovery ⬇️

artículo científico publicado el 1 de enero de 2012

Inhibitory potency of flavonoid derivatives on influenza virus neuraminidase.

artículo científico publicado en 2014

KinFragLib: Exploring the Kinase Inhibitor Space Using Subpocket-Focused Fragmentation and Recombination

artículo científico publicado en 2020

More than a look into a crystal ball: protein structure elucidation guided by molecular dynamics simulations.

artículo científico publicado en 2016

NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening.

artículo científico publicado en 2010

Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation

artículo científico publicado en 2010

Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells

artículo científico publicado en 2013

Synthesis, biological evaluation, and docking studies of new 2-furylbenzimidazoles as anti-angiogenic agents: part II.

artículo científico publicado en 2014

Synthesis, crystallographic characterization, molecular docking and biological activity of isoquinoline derivatives.

artículo científico publicado en 2017

Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting

artículo científico publicado en 2015

The impact of molecular dynamics on drug design: applications for the characterization of ligand-macromolecule complexes

artículo científico publicado en 2015

Truly Target-Focused Pharmacophore Modeling: A Novel Tool for Mapping Intermolecular Surfaces

artículo científico publicado en 2018

α-Amylase Modulation: Discovery of Inhibitors Using a Multi-Pharmacophore Approach for Virtual Screening

artículo científico publicado en 2016

β- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils

artículo científico publicado en 2014

Lista de obras de Jérémie Mortier

3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties

An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides

Anthocyanin composition, antioxidant efficiency, and α-amylase inhibitor activity of different Hungarian sour cherry varieties (Prunus cerasus L.).

Anti-virulence strategy against Brucella suis: synthesis, biological evaluation and molecular modeling of selective histidinol dehydrogenase inhibitors

Arginase Structure and Inhibition: Catalytic Site Plasticity Reveals New Modulation Possibilities

Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics.

Computational tools for in silico fragment-based drug design.

Computationally Empowered Workflow Identifies Novel Covalent Allosteric Binders for KRASG12C

Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity

Design, synthesis and structure-activity relationship of novel quinoxaline derivatives as cancer chemopreventive agent by inhibition of tyrosine kinase receptor.

Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors

Identification of PPARγ Agonists from Natural Sources Using Different In Silico Approaches

Impact of fluorination on proteolytic stability of peptides in human blood plasma

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

In silico virtual screening approaches for anti-viral drug discovery ⬇️

Inhibitory potency of flavonoid derivatives on influenza virus neuraminidase.

KinFragLib: Exploring the Kinase Inhibitor Space Using Subpocket-Focused Fragmentation and Recombination

More than a look into a crystal ball: protein structure elucidation guided by molecular dynamics simulations.

NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening.

Pyrazolo[4,3-c]isoquinolines as potential inhibitors of NF-kappaB activation

Synthesis, biological activity and structure-activity relationships of new benzoic acid-based protein tyrosine phosphatase inhibitors endowed with insulinomimetic effects in mouse C2C12 skeletal muscle cells

Synthesis, biological evaluation, and docking studies of new 2-furylbenzimidazoles as anti-angiogenic agents: part II.

Synthesis, crystallographic characterization, molecular docking and biological activity of isoquinoline derivatives.

Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting

The impact of molecular dynamics on drug design: applications for the characterization of ligand-macromolecule complexes

Truly Target-Focused Pharmacophore Modeling: A Novel Tool for Mapping Intermolecular Surfaces

α-Amylase Modulation: Discovery of Inhibitors Using a Multi-Pharmacophore Approach for Virtual Screening

β- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils