Lista de obras - Davide Lecca - Dominio Público Uruguay

A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro

artículo científico publicado en 2016

Agonist-Induced Desensitization/Resensitization of Human G Protein-Coupled Receptor 17: A Functional Cross-Talk between Purinergic and Cysteinyl-Leukotriene Ligands

scientific article published on 29 April 2011

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

artículo científico publicado en 2016

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

artículo científico publicado en 2013

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

scientific journal article

Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1.

artículo científico publicado en 2011

Deorphanisation of G protein-coupled receptors: A tool to provide new insights in nervous system pathophysiology and new targets for psycho-active drugs

artículo científico publicado en 2007

Different properties of P2X(7) receptor in hippocampal and cortical astrocytes

artículo científico publicado en 2009

Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

artículo científico publicado en 2018

Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?

artículo científico publicado en 2014

Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor.

artículo científico publicado en 2010

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells

artículo científico publicado en 2009

Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug

scientific article published on 25 February 2019

In vivo silencing of miR-125a-3p promotes myelin repair in models of white matter demyelination

artículo científico publicado en 2020

Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival, proliferation and final fate

artículo científico publicado en 2016

Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9D374Y Pathway: in vitro Characterization of its Dual Hypocholesterolemic Behavior

scientific article published on 20 July 2019

MicroRNAs change the games in central nervous system pharmacology

scientific article published on 25 June 2019

Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor

artículo científico publicado en 2014

Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes

artículo científico publicado en 2008

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

artículo científico publicado en 2017

Pathway-Focused Profiling of Oligodendrocytes Over-Expressing miR-125a-3p Reveals Alteration of Wnt and Cell-to-Cell Signaling

artículo científico publicado en 2020

Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.

artículo científico publicado en 2017

Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation

artículo científico publicado en 2011

Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

artículo científico publicado en 2020

Purinergic transmission in brain tumors and its impact on drug development

artículo científico publicado en 2015

Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death ⬇️

artículo científico publicado el 12 de abril de 2012

Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain: Role of Microglia

artículo científico publicado en 2018

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

scientific article published on 22 February 2020

Regulation of Oligodendrocyte Functions: Targeting Lipid Metabolism and Extracellular Matrix for Myelin Repair

scientific article published on 08 February 2020

Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17.

artículo científico publicado en 2010

Role of purinergic signalling in neuro-immune cells and adult neural progenitors ⬇️

artículo científico publicado el 1 de junio de 2011

SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation

artículo científico publicado en 2016

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

artículo científico publicado en 2006

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

artículo científico publicado en 2008

The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells

artículo científico publicado en 2013

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

artículo científico publicado en 2015

Uracil nucleotides: from metabolic intermediates to neuroprotection and neuroinflammation

artículo científico publicado en 2008

Ventral tegmental area/substantia nigra and prefrontal cortex rodent organotypic brain slices as an integrated model to study the cellular changes induced by oxygen/glucose deprivation and reperfusion: Effect of neuroprotective agents

article

Lista de obras de Davide Lecca

A new role for the P2Y-like GPR17 receptor in the modulation of multipotency of oligodendrocyte precursor cells in vitro

Agonist-Induced Desensitization/Resensitization of Human G Protein-Coupled Receptor 17: A Functional Cross-Talk between Purinergic and Cysteinyl-Leukotriene Ligands

CNS remyelination as a novel reparative approach to neurodegenerative diseases: The roles of purinergic signaling and the P2Y-like receptor GPR17

Changes of the GPR17 receptor, a new target for neurorepair, in neurons and glial cells in patients with traumatic brain injury

Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor

Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1.

Deorphanisation of G protein-coupled receptors: A tool to provide new insights in nervous system pathophysiology and new targets for psycho-active drugs

Different properties of P2X(7) receptor in hippocampal and cortical astrocytes

Differential local tissue permissiveness influences the final fate of GPR17-expressing oligodendrocyte precursors in two distinct models of demyelination

Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways?

Frontal affinity chromatography-mass spectrometry useful for characterization of new ligands for GPR17 receptor.

Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells

Improvement of fiber connectivity and functional recovery after stroke by montelukast, an available and safe anti-asthmatic drug

In vivo silencing of miR-125a-3p promotes myelin repair in models of white matter demyelination

Intertwining extracellular nucleotides and their receptors with Ca2+ in determining adult neural stem cell survival, proliferation and final fate

Lupin Peptide T9 (GQEQSHQDEGVIVR) Modulates the Mutant PCSK9D374Y Pathway: in vitro Characterization of its Dual Hypocholesterolemic Behavior

MicroRNAs change the games in central nervous system pharmacology

Microglia is a key player in the reduction of stroke damage promoted by the new antithrombotic agent ticagrelor

Opposite effects of uracil and adenine nucleotides on the survival of murine cardiomyocytes

Pathophysiological Role of Purines and Pyrimidines in Neurodevelopment: Unveiling New Pharmacological Approaches to Congenital Brain Diseases

Pathway-Focused Profiling of Oligodendrocytes Over-Expressing miR-125a-3p Reveals Alteration of Wnt and Cell-to-Cell Signaling

Pharmacological Properties and Biological Functions of the GPR17 Receptor, a Potential Target for Neuro-Regenerative Medicine.

Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation

Prenatal Stress Impairs Spinal Cord Oligodendrocyte Maturation via BDNF Signaling in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Purinergic transmission in brain tumors and its impact on drug development

Purinergic trophic signalling in glial cells: functional effects and modulation of cell proliferation, differentiation, and death ⬇️

Purple Corn Extract as Anti-allodynic Treatment for Trigeminal Pain: Role of Microglia

Regulation and signaling of the GPR17 receptor in oligodendroglial cells

Regulation of Oligodendrocyte Functions: Targeting Lipid Metabolism and Extracellular Matrix for Myelin Repair

Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17.

Role of purinergic signalling in neuro-immune cells and adult neural progenitors ⬇️

SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair

The regulated expression, intracellular trafficking, and membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells

The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization

Uracil nucleotides: from metabolic intermediates to neuroprotection and neuroinflammation

Ventral tegmental area/substantia nigra and prefrontal cortex rodent organotypic brain slices as an integrated model to study the cellular changes induced by oxygen/glucose deprivation and reperfusion: Effect of neuroprotective agents