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Lista de obras de Bernadette Breiden

Accumulation of glucosylceramide in the absence of the beta-glucosidase GBA2 alters cytoskeletal dynamics.

artículo científico publicado en 2015

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2.

artículo científico publicado en 2014

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis.

artículo científico publicado en 2006

Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements

artículo científico publicado en 2018

Development of an assay for the intermembrane transfer of cholesterol by Niemann-Pick C2 protein

article

Emerging mechanisms of drug-induced phospholipidosis

scientific article published on 01 December 2019

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease

artículo científico publicado en 2013

Ganglioside GM2 catabolism is inhibited by storage compounds of mucopolysaccharidoses and by cationic amphiphilic drugs

artículo científico publicado en 2019

Ganglioside Metabolism and Its Inherited Diseases

artículo científico publicado en 2018

Human acid ceramidase: processing, glycosylation, and lysosomal targeting

artículo científico publicado en 2001

Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

artículo científico publicado en 2017

Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.

artículo científico publicado en 2018

Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase.

artículo científico publicado en 2017

Loss of keratin 10 is accompanied by increased sebocyte proliferation and differentiation

artículo científico publicado en 2004

Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease

scientific article published on 07 April 2020

Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles

artículo científico publicado en 2019

Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity

artículo científico publicado en 2015

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

artículo científico publicado en 2015

Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation

artículo científico publicado en 2007

Optimization of submerged keratinocyte cultures for the synthesis of barrier ceramides

artículo científico publicado en 2007

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. ⬇️

artículo científico publicado en 2011

Physiological relevance of sphingolipid activator proteins in cultured human fibroblasts

artículo científico publicado en 2003

Postnatal requirement of the epithelial sodium channel for maintenance of epidermal barrier function

artículo científico publicado en 2007

Regulation of the NPC2 protein-mediated cholesterol trafficking by membrane lipids

artículo científico publicado en 2011

Role for LAMP-2 in endosomal cholesterol transport

artículo científico publicado en 2011

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

artículo científico publicado en 2010

Saposin A Mobilizes Lipids from Low Cholesterol and High Bis(monoacylglycerol)phosphate-containing Membranes

artículo científico publicado en 2006

Saposin B mobilizes lipids from cholesterol-poor and bis(monoacylglycero)phosphate-rich membranes at acidic pH. Unglycosylated patient variant saposin B lacks lipid-extraction capacity

artículo científico

Saposin B-dependent reconstitution of arylsulfatase A activity in vitro and in cell culture models of metachromatic leukodystrophy

artículo científico publicado en 2009

Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila

scientific article published on 15 October 2009

Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.

artículo científico publicado en 2011

Synthetic Glycoforms Reveal Carbohydrate-Dependent Bioactivity of Human Saposin D.

artículo científico publicado en 2017

TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function

artículo científico publicado en 2011

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

artículo científico publicado en 2005

The role of sphingolipid metabolism in cutaneous permeability barrier formation

artículo científico

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