Lista de obras - Juan Murga - Dominio Público Uruguay

Aldol reactions between L-erythrulose derivatives and chiral alpha-amino and alpha-fluoro aldehydes: competition between Felkin-Anh and Cornforth transition states.

artículo científico publicado en 2008

Arylpyridines, arylpyrimidines and related compounds as potential modulator agents of the VEGF, hTERT and c-Myc oncogenes

artículo científico publicado en 2019

Chlorodicyclohexylborane-mediated aldol additions of alpha,alpha'-dioxygenated ketones

artículo científico publicado en 2001

Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and M.

artículo científico publicado en 2009

Design and synthesis of pironetin analogue/colchicine hybrids and study of their cytotoxic activity and mechanisms of interaction with tubulin

scientific article published on 12 December 2014

Design and synthesis of pironetin analogue/combretastatin A-4 hybrids containing a 1,2,3-triazole ring and evaluation of their cytotoxic activity

scientific article published on 16 September 2014

Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules

artículo científico publicado en 2011

Diastereoselectivity in Organometallic Additions to the Carbonyl Group of Protected Erythrulose Derivatives

artículo científico publicado en 1998

Diastereoselectivity of the reactions of organolithium reagents with protected erythrulose oximes

Double diastereoselection in aldol reactions mediated by dicyclohexylchloroborane between L-erythrulose derivatives and chiral aldehydes. The Felkin-Anh versus Cornforth dichotomy.

artículo científico publicado en 2003

Double diastereoselection in aldol reactions mediated by dicyclohexylchloroborane between chiral aldehydes and a chiral ethyl ketone derived from L-erythrulose. synthesis of a C1-C9 fragment of the structure of the antifungal metabolite soraphen A1a

artículo científico publicado en 2005

Double diastereoselection in anti aldol reactions mediated by dicyclohexylchloroborane between an L-erythrulose derivative and chiral aldehydes

artículo científico publicado en 2012

Effects on tubulin polymerization and down-regulation of c-Myc, hTERT and VEGF genes by colchicine haloacetyl and haloaroyl derivatives.

artículo científico publicado en 2018

Inhibition of VEGF expression in cancer cells and endothelial cell differentiation by synthetic stilbene derivatives.

artículo científico publicado en 2013

Inhibitory effect of cytotoxic stilbenes related to resveratrol on the expression of the VEGF, hTERT and c-Myc genes.

artículo científico publicado en 2015

Inhibitory effect of pironetin analogue/colchicine hybrids on the expression of the VEGF, hTERT and c-Myc genes

artículo científico publicado en 2015

Interactions of long-chain homologues of colchicine with tubulin.

artículo científico publicado en 2016

On the structure of passifloricin A: asymmetric synthesis of the delta-lactones of (2Z,5S,7R,9S,11S)- and (2Z,5R,7R,9S,11S)tetrahydroxyhexacos-2-enoic acid

artículo científico publicado en 2003

Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation

artículo científico publicado en 2016

Stereoselective 1,3-dipolar cycloadditions of a chiral nitrone derived from erythrulose. An experimental and DFT theoretical study

artículo científico publicado en 2000

Stereoselective anti aldol reactions of erythrulose derivatives. Functionalized chiral d3 and d4 synthons

artículo científico publicado en 2004

Stereoselective synthesis and determination of the cytotoxic properties of spicigerolide and three of its stereoisomers

artículo científico publicado en 2003

Stereoselective synthesis and structural correction of the naturally occurring lactone stagonolide G

artículo científico publicado en 2010

Stereoselective synthesis of microcarpalide

scientific article published in 2002

Stereoselective synthesis of the antiprotozoal lactone passifloricin A and seven isomers thereof

scientific article published on 01 October 2004

Stereoselective synthesis of the cytotoxic 14-membered macrolide aspergillide A

artículo científico publicado en 2010

Stereoselective synthesis of the cytotoxic macrolide FD-891

artículo científico publicado en 2006

Stereoselective synthesis of the naturally occurring styryllactones (+)-goniofufurone and (+)-cardiobutanolide

artículo científico publicado en 2005

Stereoselective synthesis of the published structure of feigrisolide A. Structural revision of feigrisolides A and B

artículo científico publicado en 2006

Stereoselective total synthesis and absolute configuration of the natural decanolides (-)-microcarpalide and (+)-lethaloxin. Identity of (+)-lethaloxin and (+)-pinolidoxin

artículo científico publicado en 2005

Synthesis and biological evaluation as antiangiogenic agents of ureas derived from 3'-aminocombretastatin A-4

artículo científico publicado en 2018

Synthesis and biological evaluation of cyclic derivatives of combretastatin A-4 containing group 14 elements

scientific article published on 01 August 2018

Synthesis and biological evaluation of simplified pironetin analogues with modifications in the side chain and the lactone ring

artículo científico publicado en 2016

Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.

artículo científico publicado en 2013

Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B.

artículo científico publicado en 2010

Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions

artículo científico publicado en 2016

Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and downregulation of c-Myc

artículo científico publicado en 2020

Synthesis of combretastatin A-4 O-alkyl derivatives and evaluation of their cytotoxic, antiangiogenic and antitelomerase activity

artículo científico publicado en 2013

Synthesis of honokiol analogues and evaluation of their modulating action on VEGF protein secretion and telomerase-related gene expressions

artículo científico publicado en 2016

The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with Tubulin.

artículo científico publicado en 2015

Lista de obras de Juan Murga

Aldol reactions between L-erythrulose derivatives and chiral alpha-amino and alpha-fluoro aldehydes: competition between Felkin-Anh and Cornforth transition states.

Arylpyridines, arylpyrimidines and related compounds as potential modulator agents of the VEGF, hTERT and c-Myc oncogenes

Chlorodicyclohexylborane-mediated aldol additions of alpha,alpha'-dioxygenated ketones

Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines D and M.

Design and synthesis of pironetin analogue/colchicine hybrids and study of their cytotoxic activity and mechanisms of interaction with tubulin

Design and synthesis of pironetin analogue/combretastatin A-4 hybrids containing a 1,2,3-triazole ring and evaluation of their cytotoxic activity

Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules

Diastereoselectivity in Organometallic Additions to the Carbonyl Group of Protected Erythrulose Derivatives

Diastereoselectivity of the reactions of organolithium reagents with protected erythrulose oximes

Double diastereoselection in aldol reactions mediated by dicyclohexylchloroborane between L-erythrulose derivatives and chiral aldehydes. The Felkin-Anh versus Cornforth dichotomy.

Double diastereoselection in aldol reactions mediated by dicyclohexylchloroborane between chiral aldehydes and a chiral ethyl ketone derived from L-erythrulose. synthesis of a C1-C9 fragment of the structure of the antifungal metabolite soraphen A1a

Double diastereoselection in anti aldol reactions mediated by dicyclohexylchloroborane between an L-erythrulose derivative and chiral aldehydes

Effects on tubulin polymerization and down-regulation of c-Myc, hTERT and VEGF genes by colchicine haloacetyl and haloaroyl derivatives.

Inhibition of VEGF expression in cancer cells and endothelial cell differentiation by synthetic stilbene derivatives.

Inhibitory effect of cytotoxic stilbenes related to resveratrol on the expression of the VEGF, hTERT and c-Myc genes.

Inhibitory effect of pironetin analogue/colchicine hybrids on the expression of the VEGF, hTERT and c-Myc genes

Interactions of long-chain homologues of colchicine with tubulin.

On the structure of passifloricin A: asymmetric synthesis of the delta-lactones of (2Z,5S,7R,9S,11S)- and (2Z,5R,7R,9S,11S)tetrahydroxyhexacos-2-enoic acid

Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation

Stereoselective 1,3-dipolar cycloadditions of a chiral nitrone derived from erythrulose. An experimental and DFT theoretical study

Stereoselective anti aldol reactions of erythrulose derivatives. Functionalized chiral d3 and d4 synthons

Stereoselective synthesis and determination of the cytotoxic properties of spicigerolide and three of its stereoisomers

Stereoselective synthesis and structural correction of the naturally occurring lactone stagonolide G

Stereoselective synthesis of microcarpalide

Stereoselective synthesis of the antiprotozoal lactone passifloricin A and seven isomers thereof

Stereoselective synthesis of the cytotoxic 14-membered macrolide aspergillide A

Stereoselective synthesis of the cytotoxic macrolide FD-891

Stereoselective synthesis of the naturally occurring styryllactones (+)-goniofufurone and (+)-cardiobutanolide

Stereoselective synthesis of the published structure of feigrisolide A. Structural revision of feigrisolides A and B

Stereoselective total synthesis and absolute configuration of the natural decanolides (-)-microcarpalide and (+)-lethaloxin. Identity of (+)-lethaloxin and (+)-pinolidoxin

Synthesis and biological evaluation as antiangiogenic agents of ureas derived from 3'-aminocombretastatin A-4

Synthesis and biological evaluation of cyclic derivatives of combretastatin A-4 containing group 14 elements

Synthesis and biological evaluation of simplified pironetin analogues with modifications in the side chain and the lactone ring

Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.

Synthesis and biological properties of the cytotoxic 14-membered macrolides aspergillide A and B.

Synthesis and evaluation of biphenyl derivatives as potential downregulators of VEGF protein secretion and telomerase-related gene expressions

Synthesis of N-acyl Derivatives of Aminocombretastatin A-4 and Study of their Interaction with Tubulin and downregulation of c-Myc

Synthesis of combretastatin A-4 O-alkyl derivatives and evaluation of their cytotoxic, antiangiogenic and antitelomerase activity

Synthesis of honokiol analogues and evaluation of their modulating action on VEGF protein secretion and telomerase-related gene expressions

The Mechanism of the Interactions of Pironetin Analog/Combretastatin A-4 Hybrids with Tubulin.