Lista de obras - Priscille Brodin - Dominio Público Uruguay

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

artículo científico publicado en 2015

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

artículo científico publicado en 2017

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

article

A combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis

artículo científico publicado en 2022

A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening

artículo científico publicado en 2008

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters

artículo científico publicado en 2016

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening

artículo científico publicado en 2014

A new evolutionary scenario for the Mycobacterium tuberculosis complex

artículo científico publicado en 2002

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation

scientific article published on 10 May 2019

A novel specific edge effect correction method for RNA interference screenings

scientific article published on 26 November 2011

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice

artículo científico publicado en 2021

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

artículo científico publicado en 2006

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis

artículo científico publicado en 2011

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

artículo científico publicado en 2017

Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure

artículo científico publicado en 2009

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

artículo científico publicado en 2002

Benzofuro[3,2-f][1]benzopyrans: A new class of antitubercular agents

scientific article published on 17 April 2006

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family

scientific journal article

Cell Microbiology Interview

artículo científico publicado en 2020

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

artículo científico publicado en 2004

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections

artículo científico publicado en 2017

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

artículo científico publicado en 2017

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

scientific journal article

Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls

artículo científico publicado en 2019

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

artículo científico publicado en 2017

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs

artículo científico

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

artículo científico publicado en 2015

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication

artículo científico publicado en 2019

Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase

artículo científico publicado en 2000

Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides

artículo científico publicado en 2002

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

artículo científico publicado en 2006

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

artículo científico publicado en 2007

ESAT-6 proteins: protective antigens and virulence factors?

artículo científico publicado en 2004

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens

artículo científico publicado en 2004

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

artículo científico publicado en 2012

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

artículo científico publicado en 2011

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

artículo científico

Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity

artículo científico publicado en 2020

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays

artículo científico publicado en 2017

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity

artículo científico publicado en 2005

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

scientific journal article

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

artículo científico publicado en 2016

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria

artículo científico publicado en 2018

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

scientific journal article

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

artículo científico publicado en 2009

High content screening in chemical biology: overview and main challenges

artículo científico publicado en 2015

High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection

artículo científico publicado en 2006

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery

artículo científico publicado en 2010

High-content screening in infectious diseases

artículo científico publicado en 2011

High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.

artículo científico publicado en 2014

Host-directed therapies offer novel opportunities for the fight against tuberculosis

artículo científico publicado en 2017

Host-pathogen systems for early drug discovery against tuberculosis

artículo científico publicado en 2017

How can nanoparticles contribute to antituberculosis therapy?

artículo científico publicado en 2017

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.

artículo científico publicado en 2018

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

artículo científico publicado en 2016

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

artículo científico publicado en 2005

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

artículo científico publicado en 2007

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

artículo científico publicado en 2017

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

scientific journal article

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

artículo científico publicado en 2015

Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides

artículo científico publicado en 1999

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

scientific article published on 08 March 2019

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

artículo científico publicado en 2016

La mycolactone

scientific article published on 01 February 2016

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

artículo científico publicado en 2017

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

artículo científico publicado en 2014

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting

artículo científico publicado en 2009

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

artículo científico publicado en 2002

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

artículo científico publicado en 2016

Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex

artículo científico publicado en 2004

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

scientific article published on 01 January 2019

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.

artículo científico publicado en 2018

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

artículo científico publicado en 2014

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

artículo científico publicado en 2017

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

artículo científico publicado en 2016

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

artículo científico publicado en 2017

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters

scientific article published on 12 April 2019

Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis

artículo científico publicado en 2018

Phenotypic assays for Mycobacterium tuberculosis infection

artículo científico publicado en 2017

Polyphenols Inhibit Hepatitis C Virus Entry by a New Mechanism of Action

artículo científico publicado en 2015

Potent antiviral activity of Solanum rantonnetii and the isolated compounds against hepatitis C virus in vitro

Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva

artículo científico publicado en 2007

Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions

scientific journal article

Proteomics of Mycobacterium Infection: Moving towards a Better Understanding of Pathogen-Driven Immunomodulation

artículo científico publicado en 2018

Publisher Correction: Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles.

artículo científico publicado en 2018

Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis

artículo científico publicado en 2003

Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.

artículo científico publicado en 2017

STAT3 Represses Nitric Oxide Synthesis in Human Macrophages upon Mycobacterium tuberculosis Infection

artículo científico publicado en 2016

SUPPORT VECTOR MACHINES FOR AUTOMATIC DETECTION OF TUBERCULOSIS BACTERIA IN CONFOCAL MICROSCOPY IMAGES

Spatiotemporal changes of the phagosomal proteome in dendritic cells in response to LPS stimulation

artículo científico publicado en 2019

Synergy between Circular Bacteriocin AS-48 and Ethambutol against Mycobacterium tuberculosis

scholarly article by Clara Aguilar-Pérez et al published September 2018 in Antimicrobial Agents and Chemotherapy

Synthesis and antimycobacterial evaluation of benzofurobenzopyran analogues

artículo científico publicado en 2006

Systematic genetic nomenclature for type VII secretion systems.

artículo científico publicado en 2009

Testing chemical and genetic Modulators in Mycobacterium tuberculosis infected cells using phenotypic assays

artículo científico publicado en 2015

The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase

The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence

artículo científico publicado en 2012

Tuberculosis: from genome to vaccine

artículo científico publicado en 2005

[Aquatic insects and transmission of Mycobacterium ulcerans].

artículo científico publicado en 2007

Lista de obras de Priscille Brodin

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone.

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

A combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis

A fast, fully automated cell segmentation algorithm for high-throughput and high-content screening

A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening

A new evolutionary scenario for the Mycobacterium tuberculosis complex

A novel codrug made of the combination of ethionamide and its potentiating booster: synthesis, self-assembly into nanoparticles and antimycobacterial evaluation

A novel specific edge effect correction method for RNA interference screenings

Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice

An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis

Analogous mechanisms of resistance to benzothiazinones and dinitrobenzamides in Mycobacterium smegmatis

ArfGAP1 restricts Mycobacterium tuberculosis entry by controlling the actin cytoskeleton.

Automated high-throughput siRNA transfection in raw 264.7 macrophages: a case study for optimization procedure

Bacterial artificial chromosome-based comparative genomic analysis identifies Mycobacterium microti as a natural ESAT-6 deletion mutant

Benzofuro[3,2-f][1]benzopyrans: A new class of antitubercular agents

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

CD8+-T-cell responses of Mycobacterium-infected mice to a newly identified major histocompatibility complex class I-restricted epitope shared by proteins of the ESAT-6 family

Cell Microbiology Interview

Cell envelope protein PPE68 contributes to Mycobacterium tuberculosis RD1 immunogenicity independently of a 10-kilodalton culture filtrate protein and ESAT-6.

Clofazimine encapsulation in nanoporous silica particles for the oral treatment of antibiotic-resistant Mycobacterium tuberculosis infections

Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections

Control of M. tuberculosis ESAT-6 secretion and specific T cell recognition by PhoP

Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls

Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.

Cyclodextrin-based nanocarriers containing a synergic drug combination: A potential formulation for pulmonary administration of antitubercular drugs

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

Dehydrojuncusol, a Natural Phenanthrene Compound Extracted from Juncus maritimus, Is a New Inhibitor of Hepatitis C Virus RNA Replication

Determinants of Mg2+-dependent activities of recombinant human immunodeficiency virus type 1 integrase

Disruption of HIV-1 integrase-DNA complexes by short 6-oxocytosine-containing oligonucleotides

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

ESAT-6 proteins: protective antigens and virulence factors?

Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors

Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis

Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity

Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays

Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity

Functional characterization of the Mycobacterium tuberculosis serine/threonine kinase PknJ

Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

Heparin-Binding Hemagglutinin Adhesin (HBHA) Is Involved in Intracytosolic Lipid Inclusions Formation in Mycobacteria

High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling

High content screening identifies decaprenyl-phosphoribose 2' epimerase as a target for intracellular antimycobacterial inhibitors

High content screening in chemical biology: overview and main challenges

High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection

High-content imaging of Mycobacterium tuberculosis-infected macrophages: an in vitro model for tuberculosis drug discovery

High-content screening in infectious diseases

High-content screening technology combined with a human granuloma model as a new approach to evaluate the activities of drugs against Mycobacterium tuberculosis.

Host-directed therapies offer novel opportunities for the fight against tuberculosis

Host-pathogen systems for early drug discovery against tuberculosis

How can nanoparticles contribute to antituberculosis therapy?

Identification of Piperazinylbenzenesulfonamides as New Inhibitors of Claudin-1 Trafficking and Hepatitis C Virus Entry.

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

Immunogenic membrane-associated proteins of Mycobacterium tuberculosis revealed by proteomics

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

Impact of pe_pgrs33 Gene Polymorphisms on Mycobacterium tuberculosis Infection and Pathogenesis

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence

Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system

Inhibition of HIV-1 integration by mono- & bi-functionalized triple helix forming oligonucleotides

Intrinsic Antibacterial Activity of Nanoparticles Made of β-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis

Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro

La mycolactone

Legionella pneumophila Modulates Mitochondrial Dynamics to Trigger Metabolic Repurposing of Infected Macrophages

Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches

Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

LppM impact on the colonization of macrophages by Mycobacterium tuberculosis

Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex

Mitochondrial Dynamics and Activity in Legionella-Infected Cells

Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors.

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling

Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization

Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters