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Lista de obras de Andrew J. Wiemer

A live imaging cell motility screen identifies prostaglandin E2 as a T cell stop signal antagonist

artículo científico publicado en 2011

A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens

artículo científico publicado en 2018

Calpain inhibition impairs TNF-alpha-mediated neutrophil adhesion, arrest and oxidative burst

artículo científico publicado en 2009

Cyclopropene cycloadditions with annulated furans: total synthesis of (+)- and (-)-frondosin B and (+)-frondosin A.

artículo científico publicado en 2014

Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase.

artículo científico publicado en 2006

Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation.

artículo científico publicado en 2017

HMBPP Analog Prodrugs Bypass Energy-Dependent Uptake To Promote Efficient BTN3A1-Mediated Malignant Cell Lysis by Vγ9Vδ2 T Lymphocyte Effectors

artículo científico publicado en 2016

Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes.

artículo científico publicado en 2007

Live Imaging of LFA-1-Dependent T-Cell Motility and Stop Signals ⬇️

artículo científico publicado el 1 de enero de 2012

Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation

artículo científico publicado en 2016

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis.

artículo científico publicado en 2016

Phosphinophosphonates and Their Tris-pivaloyloxymethyl Prodrugs Reveal a Negatively Cooperative Butyrophilin Activation Mechanism.

artículo científico publicado en 2017

Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation

scientific article published on 26 September 2018

Probing the Ligand-Binding Pocket of BTN3A1

scientific article published on 03 July 2019

Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue

artículo científico publicado en 2008

Regulation of the Notch-ATM-abl axis by geranylgeranyl diphosphate synthase inhibition

scientific article published on 30 September 2019

Stability and Efficiency of Mixed Aryl Phosphonate Prodrugs

scientific article published on 24 July 2019

Structure-Activity Relationships of Butyrophilin 3 Ligands

scientific article published on 27 April 2020

Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.

artículo científico publicado en 2016

The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation.

artículo científico publicado en 2013

Toward Broad Spectrum Dihydrofolate Reductase Inhibitors Targeting Trimethoprim Resistant Enzymes Identified in Clinical Isolates of Methicillin Resistant Staphylococcus aureus

artículo científico publicado en 2019

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