Lista de obras - Michael D. Urbaniak - Dominio Público Uruguay

A Novel Allosteric Inhibitor of the Uridine Diphosphate N -Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

artículo científico publicado en 2013

A mechanism-inspired UDP-<i>N</i>-acetylglucosamine pyrophosphorylase inhibitor

artículo científico publicado en 2020

A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology

artículo científico publicado en 2010

Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication

artículo científico publicado en 2017

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

artículo científico publicado en 2012

Chemical synthesis and cytotoxicity of dihydroxylated cyclopentenone analogues of neocarzinostatin chromophore.

artículo científico publicado en 2003

Chromosome-scale genome sequencing, assembly and annotation of six genomes from subfamily Leishmaniinae

publication published on 06 September 2021

Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages.

artículo científico publicado en 2012

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

scientific article published in Nature

Design and synthesis of a nitrogen mustard derivative stabilized by apo-neocarzinostatin

artículo científico publicado en 2004

Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome

article

Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3'UTR

artículo científico publicado en 2018

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

artículo científico publicado en 2016

Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase.

artículo científico publicado en 2013

Genetic and structural validation ofAspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target

artículo científico publicado en 2013

Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

artículo científico publicado en 2015

Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei.

artículo científico publicado en 2013

High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics.

artículo científico publicado en 2014

Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.

artículo científico publicado en 2006

Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

artículo científico publicado en 2012

LGAAP: <i>Leishmaniinae</i> Genome Assembly and Annotation Pipeline

publication published on 22 July 2021

Molecular control of irreversible bistability during trypanosome developmental commitment

artículo científico publicado en 2015

Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

scientific article published on 12 December 2019

Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues

artículo científico publicado en 2008

Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues

artículo científico publicado en 2008

Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues.

artículo científico publicado en 2014

Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic.

artículo científico publicado en 2007

Proteome-Wide Quantitative Phosphoproteomic Analysis of Trypanosoma brucei Insect and Mammalian Life Cycle Stages

artículo científico publicado en 2020

Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

artículo científico publicado en 2008

Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei.

artículo científico publicado en 2011

The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

artículo científico publicado en 2014

The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.

artículo científico publicado en 2005

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

artículo científico publicado en 2014

Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose

artículo científico publicado en 2006

Lista de obras de Michael D. Urbaniak

A Novel Allosteric Inhibitor of the Uridine Diphosphate N -Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei

A mechanism-inspired UDP-<i>N</i>-acetylglucosamine pyrophosphorylase inhibitor

A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology

Cell cycle synchronisation of Trypanosoma brucei by centrifugal counter-flow elutriation reveals the timing of nuclear and kinetoplast DNA replication

Chemical proteomic analysis reveals the drugability of the kinome of Trypanosoma brucei.

Chemical synthesis and cytotoxicity of dihydroxylated cyclopentenone analogues of neocarzinostatin chromophore.

Chromosome-scale genome sequencing, assembly and annotation of six genomes from subfamily Leishmaniinae

Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages.

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Design and synthesis of a nitrogen mustard derivative stabilized by apo-neocarzinostatin

Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome

Dynamic regulation of the Trypanosoma brucei transferrin receptor in response to iron starvation is mediated via the 3'UTR

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase.

Genetic and structural validation ofAspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target

Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei.

High-confidence glycosome proteome for procyclic form Trypanosoma brucei by epitope-tag organelle enrichment and SILAC proteomics.

Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.

Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

LGAAP: <i>Leishmaniinae</i> Genome Assembly and Annotation Pipeline

Molecular control of irreversible bistability during trypanosome developmental commitment

Organising the cell cycle in the absence of transcriptional control: Dynamic phosphorylation co-ordinates the Trypanosoma brucei cell cycle post-transcriptionally

Probing Trypanosoma brucei glycosylphosphatidylinositol biosynthesis using novel precursor-analogues

Probing enzymes late in the trypanosomal glycosylphosphatidylinositol biosynthetic pathway with synthetic glycosylphosphatidylinositol analogues

Probing the substrate specificity of Trypanosoma brucei GlcNAc-PI de-N-acetylase with synthetic substrate analogues.

Protein-small molecule interactions in neocarzinostatin, the prototypical enediyne chromoprotein antibiotic.

Proteome-Wide Quantitative Phosphoproteomic Analysis of Trypanosoma brucei Insect and Mammalian Life Cycle Stages

Synthesis of 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei.

The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

The N-acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme.

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

Trypanosoma brucei UDP-galactose-4'-epimerase in ternary complex with NAD+ and the substrate analogue UDP-4-deoxy-4-fluoro-alpha-D-galactose