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Lista de obras de Peter K. Sorger

3D Printed frames to enable reuse and improve the fit of N95 and KN95 respirators

artículo científico publicado en 2020

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

article

A Crisis-Responsive Framework for Medical Device Development Applied to the COVID-19 Pandemic

publication published on 22 March 2021

A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling.

artículo científico publicado en 2018

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

scientific article published on 10 July 2019

A compendium of signals and responses triggered by prodeath and prosurvival cytokines

artículo científico publicado en 2005

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

artículo científico publicado en 2019

A data-driven computational model of the ErbB receptor signaling network.

artículo científico publicado en 2006

A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins

artículo científico publicado en 2012

A dual role for Bub1 in the spindle checkpoint and chromosome congression

artículo científico publicado en 2005

A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line

scientific article published on 19 February 2019

A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.

artículo científico publicado en 2007

A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: application to sepsis-apoptosis

scientific article published on 26 June 2003

A multi-center study on factors influencing the reproducibility of in vitro drug-response studies

A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses

artículo científico publicado en 2022

A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks

artículo científico publicado en 2014

A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers.

artículo científico publicado en 2019

A noncanonical Frizzled2 pathway regulates epithelial-mesenchymal transition and metastasis

artículo científico publicado en 2014

A proof of concept for biomarker-guided targeted therapy against ovarian cancer based on patient-derived tumor xenografts

artículo científico publicado en 2020

A reductionist's systems biology: opinion

artículo científico publicado en 2005

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

artículo científico publicado en 2001

A single-cell landscape of high-grade serous ovarian cancer

artículo científico publicado en 2020

A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis

artículo científico publicado en 2005

Adaptation of Human iPSC-Derived Cardiomyocytes to Tyrosine Kinase Inhibitors Reduces Acute Cardiotoxicity via Metabolic Reprogramming

scientific article published on 08 May 2019

Adaptive informatics for multifactorial and high-content biological data

artículo científico publicado en 2011

Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state

artículo científico publicado en 2017

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics

artículo científico publicado en 2017

An expanding role for cell biologists in drug discovery and pharmacology.

artículo científico publicado en 2012

Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE

artículo científico

Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE: a quality improvement study

artículo científico publicado en 2020

Analysis of growth factor signaling in genetically diverse breast cancer lines

artículo científico publicado en 2014

Analysis of kinesin motor function at budding yeast kinetochores.

artículo científico publicado en 2006

Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.

artículo científico publicado en 2011

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

artículo científico publicado en 2007

Assessing the filtration efficiency and regulatory status of N95s and nontraditional filtering face-piece respirators available during the COVID-19 pandemic

artículo científico

Assessing the quality of nontraditional N95 filtering face-piece respirators available during the COVID-19 pandemic

scientific article published on 27 July 2020

Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 18 May 2020

Automated assembly of molecular mechanisms at scale from text mining and curated databases

preprint published on 31 August 2022

Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement.

artículo científico publicado en 2002

BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response

artículo científico publicado en 2013

Bayesian network approach to cell signaling pathway modeling

artículo científico publicado en 2002

Biophysical prediction of protein-peptide interactions and signaling networks using machine learning

artículo científico publicado en 2020

CRAN-11. MULTIPLEXED IMMUNOFLUORESCENCE REVEALS POTENTIAL PD-1/PD-L1 PATHWAY VULNERABILITIES IN CRANIOPHARYNGIOMA

Cell biology: the more MAD, the merrier

artículo científico publicado en 2005

Cell stimulus and lysis in a microfluidic device with segmented gas-liquid flow

artículo científico publicado en 2005

Cells on chips

artículo científico publicado en 2006

Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes

artículo científico publicado en 2013

Centromeric chromatin and epigenetic effects in kinetochore assembly

artículo científico publicado en 1998

Changing Mad2 levels affects chromosome segregation and spindle assembly checkpoint control in female mouse meiosis I.

artículo científico publicado en 2007

Channel Embedding for Informative Protein Identification from Highly Multiplexed Images

artículo científico

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

scientific article published on 04 August 2020

Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries

scientific article published on 04 April 2019

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

artículo científico publicado en 2014

Classic and contemporary approaches to modeling biochemical reactions

artículo científico publicado en 2010

Clinical efficacy and molecular response correlates of the WEE1 inhibitor adavosertib combined with cisplatin in patients with metastatic triple-negative breast cancer (mTNBC)

artículo científico publicado en 2020

Collecting and organizing systematic sets of protein data

artículo científico publicado en 2006

Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or Synergy

artículo científico publicado en 2017

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

artículo científico publicado en 2017

Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast.

artículo científico publicado en 2006

Comparing signaling networks between normal and transformed hepatocytes using discrete logical models

artículo científico publicado en 2011

Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials

artículo científico publicado en 2020

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

scientific article published on 25 November 2020

Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway

artículo científico publicado en 2016

Coupling cell division and cell death to microtubule dynamics

artículo científico publicado en 1997

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks

artículo científico publicado en 2012

Crowdsourcing network inference: the DREAM predictive signaling network challenge

artículo científico publicado en 2011

Crystal Structure of the Yeast Inner Kinetochore Subunit Cep3p

artículo científico publicado en 2007

Cue-signal-response analysis of TNF-induced apoptosis by partial least squares regression of dynamic multivariate data

artículo científico publicado en 2004

Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single-cell Imaging

artículo científico publicado en 2016

Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation

artículo científico publicado en 2010

Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states

artículo científico publicado en 2013

Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma

artículo científico publicado en 2017

Designing Drug-Response Experiments and Quantifying their Results.

artículo científico publicado en 2017

Development and Characterization of a Wee1 Kinase Degrader

artículo científico publicado en 2019

Development of CDK2 and CDK5 Dual Degrader TMX-2172

artículo científico publicado en 2020

Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype

artículo científico publicado en 2019

Differentiable biology: using deep learning for biophysics-based and data-driven modeling of molecular mechanisms

artículo científico

Direct Lyapunov exponent analysis enables parametric study of transient signalling governing cell behaviour

artículo científico publicado en 2006

Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE).

artículo científico publicado en 2013

Discovery and resistance mechanism of a selective CDK12 degrader

artículo científico

Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity

scientific article published on 28 March 2019

Discovery of Potent and Selective Covalent Inhibitors of JNK

artículo científico publicado en 2012

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction

artículo científico publicado en 2009

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

artículo científico publicado en 2016

Electronic detection of DNA by its intrinsic molecular charge

artículo científico publicado en 2002

Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line

artículo científico publicado en 2010

Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases.

artículo científico publicado en 2018

Evolution of delayed resistance to immunotherapy in a melanoma responder

artículo científico publicado en 2021

Exceptional response and multisystem autoimmune-like toxicities associated with the same T cell clone in a patient with uveal melanoma treated with immune checkpoint inhibitors

article

Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis

artículo científico publicado en 2012

Facetto: Combining Unsupervised and Supervised Learning for Hierarchical Phenotype Analysis in Multi-Channel Image Data

artículo científico publicado en 2019

Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro.

artículo científico publicado en 1994

Failure analysis of clinical trials to test the amyloid hypothesis.

artículo científico publicado en 2014

FamPlex: a resource for entity recognition and relationship resolution of human protein families and complexes in biomedical text mining.

artículo científico publicado en 2018

Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways

scientific article published on 29 June 2020

Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models

artículo científico publicado en 2022

Flexible informatics for linking experimental data to mathematical models via DataRail

artículo científico publicado en 2008

Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold

artículo científico publicado en 2015

From word models to executable models of signaling networks using automated assembly.

artículo científico publicado en 2017

Fundamental trade-offs between information flow in single cells and cellular populations.

artículo científico publicado en 2017

Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling

artículo científico publicado en 2009

GRcalculator: an online tool for calculating and mining dose-response data.

artículo científico publicado en 2017

Genetic selection of peptide inhibitors of biological pathways.

artículo científico publicado en 1999

Genome-encoded cytoplasmic double-stranded RNAs, found in <i>C9ORF72</i> ALS-FTD brain, propagate neuronal loss

artículo científico

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

artículo científico publicado en 2016

HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

artículo científico

HSF1 phase transition mediates stress adaptation and cell fate decisions

artículo científico publicado en 2020

Heat shock factor and the heat shock response

artículo científico publicado en 1991

Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in <i>TP53-</i> and <i>BRCA1</i>-Deficient Cells

artículo científico

Hierarchical assembly of the budding yeast kinetochore from multiple subcomplexes

artículo científico publicado en 2003

Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method.

artículo científico publicado en 2015

Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer

artículo científico publicado en 2019

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

artículo científico publicado en 2018

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

INDRA-IPM: interactive pathway modeling using natural language with automated assembly

scientific article published on 01 November 2019

INNV-13. ALLELE: A CONSORTIUM FOR PROSPECTIVE GENOMICS AND FUNCTIONAL DIAGNOSTICS TO GUIDE PATIENT CARE AND TRIAL ANALYSIS IN NEWLY-DIAGNOSED GLIOBLASTOMA

Identification of essential components of the S. cerevisiae kinetochore

artículo científico publicado en 1993

Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

scientific article published on 19 March 2020

Impaired SHP2-mediated extracellular signal-regulated kinase activation contributes to gefitinib sensitivity of lung cancer cells with epidermal growth factor receptor-activating mutations

artículo científico publicado en 2010

In vitro assays for studying Saccharomyces cerevisiae kinetochore activity

artículo científico publicado en 1999

Inferring reaction network structure from single-cell, multiplex data, using toric systems theory

scientific article published on 06 December 2019

Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.

artículo científico publicado en 2018

Informatics and quantitative analysis in biological imaging

artículo científico publicado en 2003

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity

artículo científico publicado en 2019

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

artículo científico publicado en 2009

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

preprint published on 09 August 2021

Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes

artículo científico publicado en 2022

Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis

artículo científico publicado en 2014

Kinetochores distinguish GTP from GDP forms of the microtubule lattice

artículo científico publicado en 1997

Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics

artículo científico publicado en 2012

L1000CDS2: LINCS L1000 characteristic direction signatures search engine

artículo científico publicado en 2016

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures

artículo científico publicado en 2014

Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome

scientific article published on 11 April 2019

Live cell imaging of yeast.

artículo científico publicado en 2011

Logic-based models for the analysis of cell signaling networks

artículo científico publicado en 2010

Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

artículo científico publicado en 2011

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

scientific journal article

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

artículo científico

MITI minimum information guidelines for highly multiplexed tissue images

scientific article published on 01 March 2022

Machine learning identifies candidates for drug repurposing in Alzheimer's disease

artículo científico

Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells

artículo científico publicado en 2017

Measuring and Modeling Apoptosis in Single Cells

artículo científico publicado el 18 de marzo de 2011

Mechanistic model of <scp>MAPK</scp> signaling reveals how allostery and rewiring contribute to drug resistance

artículo científico publicado en 2023

Metrics other than potency reveal systematic variation in responses to cancer drugs.

artículo científico publicado en 2013

Microfluidics closes in on point-of-care assays

artículo científico publicado en 2008

Minerva: a light-weight, narrative image browser for multiplexed tissue images

artículo científico

Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade

artículo científico publicado en 2018

Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.

artículo científico publicado en 2006

Modeling a snap-action, variable-delay switch controlling extrinsic cell death

artículo científico publicado en 2008

Modulating cell-to-cell variability and sensitivity to death ligands by co-drugging

artículo científico publicado en 2013

Molecular analysis of kinetochore-microtubule attachment in budding yeast.

artículo científico publicado en 2001

Mps1 at kinetochores is essential for female mouse meiosis I

scientific journal article

Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity

scientific article published on 06 June 2019

Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma.

artículo científico publicado en 2018

Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation

artículo científico

Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data

artículo científico

Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes

artículo científico publicado en 2010

New approaches to modeling complex biochemistry

artículo científico publicado el 1 de febrero de 2011

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

artículo científico publicado en 2009

OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization

artículo científico publicado en 2024

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

artículo científico publicado en 2021

Phenotypic clustering of yeast mutants based on kinetochore microtubule dynamics

artículo científico publicado en 2007

Phosphotyrosine signaling proteins that drive oncogenesis tend to be highly interconnected

artículo científico publicado en 2013

Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins

artículo científico publicado en 2006

Physicochemical modelling of cell signalling pathways.

artículo científico publicado en 2006

Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors

artículo científico

Probing the Architecture of a Simple Kinetochore Using DNA–Protein Crosslinking

artículo científico publicado el 15 de diciembre de 1997

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines

artículo científico publicado en 2013

Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation

artículo científico publicado en 2016

Programming biological models in Python using PySB

artículo científico publicado en 2013

Properties of cell death models calibrated and compared using Bayesian approaches

artículo científico publicado en 2013

Protein structure prediction by AlphaFold2: are attention and symmetries all you need?

Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging

scientific article published on 18 September 2019

Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics

artículo científico publicado en 2017

Quantitative analysis of pathways controlling extrinsic apoptosis in single cells

artículo científico publicado en 2008

Quantitative microscopy of green fluorescent protein-labeled yeast.

artículo científico publicado en 2002

Rapid phospho-turnover by receptor tyrosine kinases impacts downstream signaling and drug binding

artículo científico publicado en 2011

Rapid prototyping and clinical testing of a reusable face shield for health care workers responding to the COVID-19 pandemic

scientific article published on 15 April 2020

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

artículo científico publicado en 2020

Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks

artículo científico publicado en 2020

Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

artículo científico

Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008)

artículo científico publicado en 2008

Reproducibility will only come with data liberation

artículo científico publicado en 2016

Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1

artículo científico publicado en 2020

S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase

artículo científico publicado en 2013

SARS-CoV-2 infection protects against rechallenge in rhesus macaques

artículo científico publicado en 2020

SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma

artículo científico publicado en 2020

Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data

artículo científico

Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism

artículo científico publicado en 2020

Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

artículo científico publicado en 2012

Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma

artículo científico publicado en 2022

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo.

artículo científico publicado en 2013

Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

scientific article published in 2022

Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.

artículo científico publicado en 2018

Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions

artículo científico publicado en 2011

Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

artículo científico publicado en 2013

Spindle checkpoint proteins and chromosome-microtubule attachment in budding yeast

artículo científico publicado en 2004

Structure and assembly of turnip crinkle virus. II. Mechanism of reassembly in vitro

artículo científico publicado en 1986

Structure, Function, and Regulation of Budding Yeast Kinetochores

artículo científico publicado el 1 de enero de 2003

Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine

scientific article published on 30 January 2020

Structure-guided development of covalent TAK1 inhibitors

artículo científico publicado en 2016

Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors

artículo científico publicado en 2016

Surviving apoptosis: life-death signaling in single cells.

artículo científico

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

artículo científico publicado en 2009

Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

artículo científico publicado en 2015

Systematic calibration of a cell signaling network model

artículo científico publicado en 2010

Systems biology and combination therapy in the quest for clinical efficacy.

artículo científico publicado en 2006

Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

artículo científico

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

artículo científico publicado en 2017

The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution

artículo científico publicado en 2022

The glucose-regulated protein grp94 is related to heat shock protein hsp90.

artículo científico publicado en 1987

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

artículo científico publicado en 2006

The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation

The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data

artículo científico publicado en 2009

The response of human epithelial cells to TNF involves an inducible autocrine cascade

artículo científico publicado en 2006

The yeast DASH complex forms closed rings on microtubules.

artículo científico publicado en 2005

Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling

artículo científico

Timing and checkpoints in the regulation of mitotic progression

artículo científico publicado en 2004

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

scientific article published on 04 December 2019

Towards a rigorous assessment of systems biology models: the DREAM3 challenges

artículo científico publicado en 2010

Tracing the pathway of spindle assembly checkpoint signaling

artículo científico publicado en 2001

Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli

artículo científico publicado en 2011

Trimerization of a yeast transcriptional activator via a coiled-coil motif

artículo científico publicado en 1989

Two genes required for the binding of an essential Saccharomyces cerevisiae kinetochore complex to DNA.

artículo científico publicado en 1995

Yeast heat shock factor contains separable transient and sustained response transcriptional activators

artículo científico publicado en 1990

Yeast heat shock factor is an essential DNA-binding protein that exhibits temperature-dependent phosphorylation

artículo científico publicado en 1988

Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy

artículo científico publicado en 2005

p31(comet) acts to ensure timely spindle checkpoint silencing subsequent to kinetochore attachment

artículo científico publicado en 2011