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Lista de obras de Miguel A. Valvano

A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.

artículo científico publicado en 2016

A Burkholderia cenocepacia MurJ (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability

artículo científico publicado en 2014

A Burkholderia cenocepacia gene encoding a non-functional tyrosine phosphatase is required for the delayed maturation of the bacteria-containing vacuoles in macrophages.

artículo científico publicado en 2014

A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo.

artículo científico publicado en 2006

A decade of Burkholderia cenocepacia virulence determinant research

artículo científico publicado en 2010

A general protein O-glycosylation machinery conserved in Burkholderia species improves bacterial fitness and elicits glycan immunogenicity in humans

scientific article published on 26 July 2019

A glycoengineered antigen exploiting a conserved protein O-glycosylation pathway in the Burkholderia genus for detection of glanders infections

artículo científico publicado en 2021

A markerless deletion method for genetic manipulation of Burkholderia cenocepacia and other multidrug-resistant gram-negative bacteria

artículo científico publicado en 2014

A minor catalase/peroxidase from Burkholderia cenocepacia is required for normal aconitase activity

artículo científico publicado en 2005

A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability

artículo científico publicado en 2007

A quorum-quenching approach to investigate the conservation of quorum-sensing-regulated functions within the Burkholderia cepacia complex

artículo científico publicado en 2006

A system for the construction of targeted unmarked gene deletions in the genus Burkholderia

artículo científico publicado en 2008

A two-tier model of polymyxin B resistance in Burkholderia cenocepacia

artículo científico publicado en 2010

Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepacia

artículo científico publicado en 2015

Activation of the pyrin inflammasome by intracellular Burkholderia cenocepacia

artículo científico publicado en 2012

Akt-mediated proinflammatory response of mononuclear phagocytes infected with Burkholderia cenocepacia occurs by a novel GSK3β-dependent, IκB kinase-independent mechanism.

artículo científico publicado en 2011

Aminoarabinose is essential for lipopolysaccharide export and intrinsic antimicrobial peptide resistance inBurkholderia cenocepacia†

artículo científico publicado en 2012

An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling.

artículo científico publicado en 2007

An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

artículo científico publicado en 2003

An evolutionary conserved detoxification system for membrane lipid-derived peroxyl radicals in Gram-negative bacteria

artículo científico publicado en 2022

An expression vector containing a rhamnose-inducible promoter provides tightly regulated gene expression in Burkholderia cenocepacia

artículo científico publicado en 2005

An in vitro screen of bacterial lipopolysaccharide biosynthetic enzymes identifies an inhibitor of ADP-heptose biosynthesis.

artículo científico publicado en 2006

Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance

artículo científico publicado en 2017

Antimicrobial heteroresistance: an emerging field in need of clarity.

artículo científico

ArnT proteins that catalyze the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases.

artículo científico publicado en 2015

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance

artículo científico publicado en 2009

Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.

artículo científico publicado en 2011

BcsKC is an essential protein for the type VI secretion system activity in Burkholderia cenocepacia that forms an outer membrane complex with BcsLB

artículo científico publicado en 2010

Biological efficacy of electroless-deposited silver on plasma activated polyurethane

artículo científico publicado en 2003

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B

artículo científico publicado en 2009

Biosynthesis of inner core lipopolysaccharide in enteric bacteria identification and characterization of a conserved phosphoheptose isomerase

artículo científico publicado en 1996

Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli

artículo científico publicado en 2002

Burkholderia cenocepacia BC2L-C Is a Super Lectin with Dual Specificity and Proinflammatory Activity

artículo científico publicado en 2011

Burkholderia cenocepacia C5424 produces a pigment with antioxidant properties using a homogentisate intermediate.

artículo científico publicado en 2007

Burkholderia cenocepacia Lipopolysaccharide Modification and Flagellin Glycosylation Affect Virulence but Not Innate Immune Recognition in Plants

artículo científico publicado en 2015

Burkholderia cenocepacia O polysaccharide chain contributes to caspase-1-dependent IL-1beta production in macrophages.

artículo científico publicado en 2010

Burkholderia cenocepacia and Salmonella enterica ArnT proteins that transfer 4-amino-4-deoxy-l-arabinose to lipopolysaccharide share membrane topology and functional amino acids.

artículo científico publicado en 2015

Burkholderia cenocepacia disrupts host cell actin cytoskeleton by inactivating Rac and Cdc42

artículo científico publicado en 2011

Burkholderia cenocepacia requires a periplasmic HtrA protease for growth under thermal and osmotic stress and for survival in vivo

artículo científico publicado en 2007

Burkholderia cenocepacia requires the RpoN sigma factor for biofilm formation and intracellular trafficking within macrophages

artículo científico publicado en 2008

Burkholderia cenocepacia-induced delay of acidification and phagolysosomal fusion in cystic fibrosis transmembrane conductance regulator (CFTR)-defective macrophages

artículo científico publicado en 2008

Burkholderia cepacia complex isolates survive intracellularly without replication within acidic vacuoles of Acanthamoeba polyphaga

artículo científico publicado en 2004

Burkholderia multivorans survival and trafficking within macrophages.

artículo científico publicado en 2012

Characterization of the AtsR hybrid sensor kinase phosphorelay pathway and identification of its response regulator in Burkholderia cenocepacia.

artículo científico publicado en 2013

Characterization of the exopolysaccharide biosynthesis pathway in Myxococcus xanthus

artículo científico publicado en 2020

Characterization of the highly conserved VFMGD motif in a bacterial polyisoprenyl-phosphate N-acetylaminosugar-1-phosphate transferase.

artículo científico publicado en 2012

Chemical communication of antibiotic resistance by a highly resistant subpopulation of bacterial cells

artículo científico publicado en 2013

Cofactor- and substrate-binding domains in flavin-dependent N-hydroxylating enzymes

artículo científico publicado en 1998

Common themes in glycoconjugate assembly using the biogenesis of O-antigen lipopolysaccharide as a model system.

artículo científico publicado en 2011

Communication is key: do bacteria use a universal 'language' to spread resistance?

artículo científico publicado en 2013

Construction and evaluation of plasmid vectors optimized for constitutive and regulated gene expression in Burkholderia cepacia complex isolates.

artículo científico publicado en 2002

Construction of aminoglycoside-sensitive Burkholderia cenocepacia strains for use in studies of intracellular bacteria with the gentamicin protection assay.

artículo científico publicado en 2010

Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia

artículo científico publicado en 2009

Current Advances in <i>Burkholderia</i> Vaccines Development

artículo científico publicado en 2020

Dam methylation controls O-antigen chain length in Salmonella enterica serovar enteritidis by regulating the expression of Wzz protein

artículo científico publicado en 2009

Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery

scientific journal article

Different sugar residues of the lipopolysaccharide outer core are required for early interactions of Salmonella enterica serovars Typhi and Typhimurium with epithelial cells

artículo científico publicado en 2010

Diphenylamine increases cloacin DF13 sensitivity in avian septicemic strains of Escherichia coli

artículo científico publicado el 1 de septiembre de 1992

Distinct functional domains of the Salmonella enterica WbaP transferase that is involved in the initiation reaction for synthesis of the O antigen subunit

artículo científico publicado en 2008

Diverse pathogenicity of Burkholderia cepacia complex strains in the Caenorhabditis elegans host model

scientific article published on 01 September 2005

Draft Genome Sequence of a Pseudomonas aeruginosa Sequence Type 3351 Strain Exhibiting High-Level Resistance to Polymyxins in a Pediatric Patient with Cystic Fibrosis in Mexico

artículo científico publicado en 2020

Elucidation of the Burkholderia cenocepacia hopanoid biosynthesis pathway uncovers functions for conserved proteins in hopanoid-producing bacteria.

artículo científico publicado en 2014

Engineering N-linked protein glycosylation with diverse O antigen lipopolysaccharide structures in Escherichia coli.

artículo científico publicado en 2005

Escherichia coli and Pseudomonas aeruginosa lipopolysaccharide O-antigen ligases share similar membrane topology and biochemical properties

artículo científico publicado en 2018

Export of O-specific lipopolysaccharide.

artículo científico publicado en 2003

Extreme antimicrobial peptide and polymyxin B resistance in the genus Burkholderia.

artículo científico publicado en 2011

Functional analysis of predicted coiled-coil regions in the Escherichia coli K-12 O-antigen polysaccharide chain length determinant Wzz.

artículo científico publicado en 2008

Functional analysis of the C-terminal domain of the WbaP protein that mediates initiation of O antigen synthesis in Salmonella enterica

artículo científico publicado en 2010

Functional analysis of the glycero-manno-heptose 7-phosphate kinase domain from the bifunctional HldE protein, which is involved in ADP-L-glycero-D-manno-heptose biosynthesis

artículo científico publicado en 2005

Functional analysis of the large periplasmic loop of the Escherichia coli K-12 WaaL O-antigen ligase

artículo científico publicado en 2008

Functional characterization and membrane topology of Escherichia coli WecA, a sugar-phosphate transferase initiating the biosynthesis of enterobacterial common antigen and O-antigen lipopolysaccharide

artículo científico publicado en 2007

Functional characterization of the initiation enzyme of S-layer glycoprotein glycan biosynthesis in Geobacillus stearothermophilus NRS 2004/3a

artículo científico publicado en 2007

Global changes in gene expression by the opportunistic pathogen Burkholderia cenocepacia in response to internalization by murine macrophages

artículo científico publicado en 2012

Growth-phase regulation of lipopolysaccharide O-antigen chain length influences serum resistance in serovars of Salmonella.

artículo científico publicado en 2008

High confidence prediction of essential genes in Burkholderia cenocepacia

artículo científico publicado en 2012

Hopanoid production is required for low-pH tolerance, antimicrobial resistance, and motility in Burkholderia cenocepacia

artículo científico publicado en 2011

Identification and molecular analysis of cable pilus biosynthesis genes in Burkholderia cepacia

artículo científico publicado en 2003

Identification of Burkholderia cenocepacia genes required for bacterial survival in vivo

artículo científico publicado en 2004

Identification of a UDP-Gal: GlcNAc-R galactosyltransferase activity in Escherichia coli VW187.

artículo científico publicado en 2005

Identification of a general secretory pathway in a human isolate of Burkholderia vietnamiensis (formerly B. cepacia complex genomovar V) that is required for the secretion of hemolysin and phospholipase C activities

artículo científico publicado en 2002

Identification of synergists that potentiate the action of polymyxin B against Burkholderia cenocepacia.

artículo científico publicado en 2015

Identification of the Wzx flippase, Wzy polymerase and sugar-modifying enzymes for spore coat polysaccharide biosynthesis in Myxococcus xanthus

artículo científico publicado en 2020

Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses

artículo científico publicado en 2014

Identification of the lipopolysaccharide O-antigen biosynthesis priming enzyme and the O-antigen ligase in Myxococcus xanthus: critical role of LPS O-antigen in motility and development

artículo científico publicado en 2019

Inactivation of macrophage Rab7 by Burkholderia cenocepacia.

artículo científico publicado en 2010

Infections by Burkholderia spp.: the psychodramatic life of an opportunistic pathogen

artículo científico publicado en 2006

Interplay of the Wzx translocase and the corresponding polymerase and chain length regulator proteins in the translocation and periplasmic assembly of lipopolysaccharide o antigen

artículo científico publicado en 2006

Intracellular survival of Burkholderia cepacia complex in phagocytic cells

artículo científico publicado en 2015

Lipopolysaccharide modification in Gram-negative bacteria during chronic infection.

artículo científico publicado en 2016

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

artículo científico publicado en 2019

Macrophage dysfunction in cystic fibrosis: Nature or nurture?

scientific article published on 17 July 2020

Membrane Topology and Identification of Critical Amino Acid Residues in the Wzx O-Antigen Translocase from Escherichia coli O157:H7.

artículo científico publicado en 2011

Membrane topology and identification of critical amino acid residues in the Wzx O-antigen translocase from Escherichia coli O157:H4.

artículo científico publicado en 2010

Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death.

artículo científico publicado en 2007

Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies signal analogues

scientific article published on 27 May 2019

Nasal immunization with Burkholderia multivorans outer membrane proteins and the mucosal adjuvant adamantylamide dipeptide confers efficient protection against experimental lung infections with B. multivorans and B. cenocepacia

artículo científico publicado en 2007

Non-genetic mechanisms communicating antibiotic resistance: rethinking strategies for antimicrobial drug design.

artículo científico

Novel antibiotic combinations proposed for treatment of Burkholderia cepacia complex infections.

artículo científico publicado en 2017

O-antigen modal chain length in Shigella flexneri 2a is growth-regulated through RfaH-mediated transcriptional control of the wzy gene

artículo científico publicado en 2007

Phage life cycles behind bacterial biodiversity.

artículo científico publicado en 2017

Phenotypic characterization of an international Pseudomonas aeruginosa reference panel: strains of cystic fibrosis (CF) origin show less in vivo virulence than non-CF strains.

artículo científico publicado en 2015

Physico-chemical characterization of a recombinant cytoplasmic form of lysine: N6-hydroxylase

artículo científico publicado en 1993

Polysaccharide co-polymerases: the enigmatic conductors of the O-antigen assembly orchestra.

artículo científico

Prevalence of indeterminate genetic species of Burkholderia cepacia complex in a cystic fibrosis center in Argentina

artículo científico publicado en 2008

Putrescine reduces antibiotic-induced oxidative stress as a mechanism of modulation of antibiotic resistance in Burkholderia cenocepacia.

artículo científico publicado en 2014

Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.

artículo científico publicado en 2015

Reconstitution of O-specific lipopolysaccharide expression in Burkholderia cenocepacia strain J2315, which is associated with transmissible infections in patients with cystic fibrosis

artículo científico publicado en 2005

RpoS and RpoN are involved in the growth-dependent regulation of rfaH transcription and O antigen expression in Salmonella enterica serovar Typhi

artículo científico publicado en 2004

Structural and kinetic characterization of the LPS biosynthetic enzyme D-alpha,beta-D-heptose-1,7-bisphosphate phosphatase (GmhB) from Escherichia coli

artículo científico publicado en 2010

Structural–Functional Studies of Burkholderia cenocepacia d -Glycero-β- d -manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties

artículo científico publicado en 2013

Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants

artículo científico publicado en 2008

Structure of O-Antigen and Hybrid Biosynthetic Locus in Burkholderia cenocepacia Clonal Variants Recovered from a Cystic Fibrosis Patient.

artículo científico publicado en 2017

Structure-guided investigation of lipopolysaccharide O-antigen chain length regulators reveals regions critical for modal length control

artículo científico publicado en 2011

Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity

artículo científico publicado en 2010

Subfunctionalization influences the expansion of bacterial multidrug antibiotic resistance.

artículo científico publicado en 2017

Substrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems

artículo científico publicado en 2006

Surface expression of O-specific lipopolysaccharide in Escherichia coli requires the function of the TolA protein

scientific article published on 01 October 2000

Survival and persistence of opportunistic Burkholderia species in host cells.

artículo científico publicado en 2005

Synthetic Phosphodiester-Linked 4-Amino-4-deoxy-l-arabinose Derivatives Demonstrate that ArnT is an Inverting Aminoarabinosyl Transferase

scientific article published on 22 October 2019

The ArcAB two-component regulatory system promotes resistance to reactive oxygen species and systemic infection by Salmonella Typhimurium

artículo científico publicado en 2018

The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation

artículo científico publicado en 2016

The Burkholderia cenocepacia sensor kinase hybrid AtsR is a global regulator modulating quorum-sensing signalling

artículo científico publicado en 2012

The C-terminal domain of the Salmonella enterica WbaP (UDP-galactose:Und-P galactose-1-phosphate transferase) is sufficient for catalytic activity and specificity for undecaprenyl monophosphate

artículo científico publicado en 2011

The GalF protein of Escherichia coli is not a UDP-glucose pyrophosphorylase but interacts with the GalU protein possibly to regulate cellular levels of UDP-glucose.

artículo científico publicado en 1996

The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia

artículo científico publicado en 2017

The N-terminal region of the Escherichia coli WecA (Rfe) protein, containing three predicted transmembrane helices, is required for function but not for membrane insertion.

artículo científico publicado en 2000

The Type VI secretion system of Burkholderia cenocepacia affects multiple Rho family GTPases disrupting the actin cytoskeleton and the assembly of NADPH oxidase complex in macrophages.

artículo científico publicado en 2011

The WaaL O-antigen lipopolysaccharide ligase has features in common with metal ion-independent inverting glycosyltransferases.

artículo científico publicado en 2011

The activity of a putative polyisoprenol-linked sugar translocase (Wzx) involved in Escherichia coli O antigen assembly is independent of the chemical structure of the O repeat

artículo científico publicado en 1999

The cellular level of O-antigen polymerase Wzy determines chain length regulation by WzzB and WzzpHS-2 in Shigella flexneri 2a.

artículo científico publicado en 2009

The mgtC gene of Burkholderia cenocepacia is required for growth under magnesium limitation conditions and intracellular survival in macrophages.

artículo científico

The normal chain length distribution of the O antigen is required for the interaction of Shigella flexneri 2a with polarized Caco-2 cells

artículo científico publicado en 2012

The outer core lipopolysaccharide of Salmonella enterica serovar Typhi is required for bacterial entry into epithelial cells.

artículo científico publicado en 2006

The rfaE gene from Escherichia coli encodes a bifunctional protein involved in biosynthesis of the lipopolysaccharide core precursor ADP-L-glycero-D-manno-heptose

artículo científico publicado en 2000

The suhB gene of Burkholderia cenocepacia is required for protein secretion, biofilm formation, motility and polymyxin B resistance.

artículo científico publicado en 2012

The temperate Burkholderia phage AP3 of the Peduovirinae shows efficient antimicrobial activity against B. cenocepacia of the IIIA lineage.

artículo científico publicado en 2016

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia

artículo científico publicado en 2013

The wbbD gene of E. coli strain VW187 (O7:K1) encodes a UDP-Gal: GlcNAc{alpha}-pyrophosphate-R {beta}1,3-galactosyltransferase involved in the biosynthesis of O7-specific lipopolysaccharide

artículo científico publicado en 2004

Topological analysis of the Escherichia coli WcaJ protein reveals a new conserved configuration for the polyisoprenyl-phosphate hexose-1-phosphate transferase family.

artículo científico publicado en 2015

Transcriptional responses of Burkholderia cenocepacia to polymyxin B in isogenic strains with diverse polymyxin B resistance phenotypes.

artículo científico publicado en 2011

Two distinct but interchangeable mechanisms for flipping of lipid-linked oligosaccharides

scientific journal article

Tyrosine Phosphorylation and Dephosphorylation in Burkholderia cenocepacia Affect Biofilm Formation, Growth under Nutritional Deprivation, and Pathogenicity

artículo científico publicado en 2015

Undecaprenyl phosphate recycling comes out of age.

artículo científico publicado en 2007

Validation of membrane protein topology models by oxidative labeling and mass spectrometry.

artículo científico publicado en 2012

Vitamin E Increases Antimicrobial Sensitivity by Inhibiting Bacterial Lipocalin Antibiotic Binding

scientific article published in 2018

Wzx proteins involved in biosynthesis of O antigen function in association with the first sugar of the O-specific lipopolysaccharide subunit

artículo científico publicado en 2004

tolQ is required for cloacin DF13 susceptibility in Escherichia coli expressing the aerobactin/cloacin DF13 receptor IutA.

artículo científico publicado en 1992